We narrowed to 17,819 results for: Mut

1. pCMV-PE7-mutant (Q20A_Y23A_Y24F_F35A)

   Plasmid

   #224123

   Purpose

   Mammalian expression of SpCas9 PE7 mutant prime editor (Q20A_Y23A_Y24F_F35A)

   Depositor

   Brittany Adamson

   Article

   Yan et al Nature. 2024 Apr 3. doi: 10.1038/s41586-

   Insert

   PE7-mutant (Q20A_Y23A_Y24F_F35A)
   

   Use

   Tags

   SV40 bpNLS and c-Myc NLS

   Expression

   Mammalian

   Mutation

   Q20A_Y23A_Y24F_F35A in La(SSB)1-194

   Promoter

   CMV

   Available Since

   Aug. 19, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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2. pCAG-Kir2.1Mut-T2A-tdTomato

   Plasmid

   #60644

   Purpose

   Expresses Kir2.1Mut-T2A-tdTomato

   Depositor

   Massimo Scanziani

   Article

   Xue et al Nature. 2014 Jul 31;511(7511):596-600. d

   Insert

   Kcnj2 (Kcnj2 Mouse)
   

   Use

   Tags

   myc

   Expression

   Mammalian

   Mutation

   GYG to AAA (aa144-146)

   Promoter

   Available Since

   Oct. 27, 2014

   Availability

   Academic Institutions and Nonprofits only

   

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3. pcDNA3.1+-mutTornado-split-nLuc

   Plasmid

   #212707

   Purpose

   Tornado split nLuc with a mutated 3' ribozyme so that circularization cannot occur.

   Depositor

   Samie Jaffrey

   Article

   Unti et al Cell Chem Biol. 2023 Oct 13:S2451-9456(2

   Insert

   mutTornado-CVB3-split-nLuc
   

   Use

   Tags

   Expression

   Mutation

   Deleted the partial 3'ribozyme sequence in T…

   Promoter

   Available Since

   Feb. 5, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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4. pcDNA3-Flag-Tet2 CD Mut

   Plasmid

   #72220

   Purpose

   Express flag-tagged mouse Tet2 catalytic domain - catalytic dead mutant.

   Depositor

   Yi Zhang

   Article

   Ito et al Science. 2011 Sep 2;333(6047):1300-3. do

   Insert

   Ten-Eleven Translocation 2 (Tet2 Mouse)
   

   Use

   Tags

   flag

   Expression

   Mammalian

   Mutation

   The plasmid expresses TET2 catalytic domain (cata…

   Promoter

   CMV

   Available Since

   May 1, 2018

   Availability

   Academic Institutions and Nonprofits only

5. pCS2 GFP-GSK3mut-MAPK

   Plasmid

   #29690

   Purpose

   GFP reporter protein fused to three mutated GSK3 phosphorylation sites

   Depositor

   Edward De Robertis

   Article

   Taelman et al Cell. 2010 Dec 23. 143(7):1136-48.

   Insert

   GFP glycogen synthase kinase 3 recognition site mutated primed by MAPK
   

   Use

   Tags

   Flag and Flag-EGFP

   Expression

   Mammalian

   Mutation

   recognition sites only, and E3 ligase site, GSK3 …

   Promoter

   SP6

   Available Since

   Jan. 6, 2012

   Availability

   Academic Institutions and Nonprofits only

   

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6. pPB_TRE3G_scFV-sfGFP-Kmt5cFL-CatMut

   Plasmid

   #235590

   Purpose

   Dox-inducible expression of control catalytic-mutant Kmt5c CD fused with scFV

   Depositor

   Jamie Hackett

   Article

   Policarpi et al Nat Genet. 2024 Jun;56(6):1168-1180. doi

   Insert

   Kmt5c (Kmt5c Mouse)
   

   Use

   CRISPR

   Tags

   Expression

   Mutation

   NHDC182-185AAAG

   Promoter

   Available Since

   April 30, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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7. pAAV-hSyn-GRAB_g5-HT3.0mut

   Plasmid

   #208718

   Purpose

   Expresses the green 5-HT sensor GRAB_g5-HT3.0mut in neurons

   Depositor

   Yulong Li

   Article

   Deng et al bioRxiv 2023.05.27.542566

   Insert

   Green fluorescent 5-HT sensor GRAB_g5-HT3.0mut
   

   Use

   AAV

   Tags

   Expression

   Mutation

   Promoter

   hSyn

   Available Since

   Oct. 30, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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8. pBV-Luc mut MBS1-4

   Plasmid

   #16565

   Depositor

   Bert Vogelstein

   Article

   Hermeking et al Proc Natl Acad Sci U S A. 2000 Feb 29. 9

   Insert

   c-MYC binding sites (MYC Human)
   

   Use

   Luciferase

   Tags

   Luciferase

   Expression

   Mammalian

   Mutation

   Mutant MBS1-4

   Promoter

   Available Since

   March 24, 2008

   Availability

   Academic Institutions and Nonprofits only

9. pPB_TRE3G_scFV-sfGFP-Prdm9CD-CatMut

   Plasmid

   #235586

   Purpose

   Dox-inducible expression of control catalytic-mutant Prdm9 CD fused with scFV

   Depositor

   Jamie Hackett

   Article

   Policarpi et al Nat Genet. 2024 Jun;56(6):1168-1180. doi

   Insert

   Prdm9 (Prdm9 Mouse)
   

   Use

   CRISPR

   Tags

   Expression

   Mutation

   G282A

   Promoter

   Available Since

   April 30, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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10. pSC101-GFPmut2-mScarlet-I TAA

    Plasmid

    #208187

    Purpose

    nonsense mistranslation, TAA stop

    Depositor

    Tanel Tenson

    Article

    Hinnu et al Sci Rep. 2024 Mar 22;14(1):6883. doi: 10

    Inserts

    GFPmut2
    mScarlet-I
    

    Use

    Reporter

    Tags

    Expression

    Bacterial

    Mutation

    Insertion 6TAA*(stop) 7AGT(Ser)

    Promoter

    Ptet+dnaK P1

    Available Since

    March 25, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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11. pARC8-LambdaRedBeta-EcSSB-EcMutLE32K

    Plasmid

    #162576

    Purpose

    Arabinose inducible recombineering plasmid encoding Lambda-Red Beta with EcSSB for use with dsDNA templates and enhanced recombination efficiency. Contains a dominant negative mismatch repair protein.

    Depositor

    George Church

    Article

    Filsinger et al Nat Chem Biol. 2021 Jan 18. pii: 10.1038

    Inserts

    Lambda Red-Beta
    E. coli SSB
    EcMutLE32K
    

    Use

    Tags

    Expression

    Bacterial

    Mutation

    E32K mutated to give dominant negative phenotype

    Promoter

    pBAD

    Available Since

    May 22, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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12. pAAV-hsyn-GRAB_rDA-mut

    Plasmid

    #140558

    Purpose

    Expresses the red fluorescent DA-insensitive control sensor GRAB_rDA-mut in neurons

    Depositor

    Yulong Li

    Article

    Sun et al Nat Methods. 2020 Nov;17(11):1156-1166.

    Has Service

    AAV9

    Insert

    Red fluorescent DA-insensitive sensor GRAB_rDA-mut (control sensor)
    

    Use

    AAV

    Tags

    Expression

    Mutation

    Promoter

    hSyn

    Available Since

    July 29, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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13. pPB_TRE3G_scFV-sfGFP-Ring1bCD-CatMut

    Plasmid

    #235583

    Purpose

    Dox-inducible expression of control catalytic-mutant Ring1b CD fused with scFV

    Depositor

    Jamie Hackett

    Article

    Policarpi et al Nat Genet. 2024 Jun;56(6):1168-1180. doi

    Insert

    Ring1b (Rnf2 Mouse)
    

    Use

    CRISPR

    Tags

    Expression

    Mutation

    I53S

    Promoter

    Available Since

    April 30, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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14. Marathon-RT pentamutant for Split-PE (pEH107)

    Plasmid

    #190110

    Purpose

    Expresses Marathon-RT pentamutant (D14R-N26R-D74R-N116K-N197R)

    Depositor

    Keith Joung

    Article

    Grunewald et al Nat Biotechnol. 2023 Mar;41(3):337-343.

    Insert

    Marathon-RT
    

    Use

    Tags

    bpNLS

    Expression

    Mammalian

    Mutation

    D14R, N26R, D74R, N116K, N197R

    Promoter

    CMV

    Available Since

    Sept. 26, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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15. pIS1-Eef25UTR-TOPmut-renilla

    Plasmid

    #38236

    Depositor

    David Sabatini

    Article

    Thoreen et al Nature. 2012 May 2;485(7396):109-13. doi

    Insert

    Eef2_TOPm_5UTR/Renilla (Eef2 Mouse)
    

    Use

    Luciferase

    Tags

    Expression

    Mammalian

    Mutation

    The first nucleotides of the 5' UTR were cha…

    Promoter

    Endogenous Eef2

    Available Since

    Nov. 7, 2012

    Availability

    Academic Institutions and Nonprofits only

16. pQdCas9.luxR(mut)-sggfp

    Plasmid

    #236185

    Purpose

    The plasmid pQdCas9.luxR(mut)-sggfp expresses the dCas9 endonuclease and the sgRNA targeting the GFP gene. Additionally, this plasmid contains a mutation in the luxR gene.

    Depositor

    Radhakrishnan Mahadevan

    Insert

    Quorum sensing cassette luxI, mutated luxR, and the LuxR-dependent promoter pLuxI , dCas9, and sgRNA for GFP gene
    

    Use

    Tags

    Expression

    Mutation

    Promoter

    Quorum sensing promoter

    Available Since

    May 6, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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17. pMUT2-pFF-41.5-mCherry

    Plasmid

    #192863

    Purpose

    pMUT2 based vector for sensing oxygen in E. coli Nissle 1917

    Depositor

    Morten Sommer

    Article

    Vaaben et al ACS Synth Biol. 2022 Dec 16;11(12):4184-

    Insert

    Oxygen inducible promoter
    

    Use

    Tags

    Expression

    Bacterial

    Mutation

    Promoter

    Available Since

    July 5, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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18. BcatMutS33/S37.T41/S45

    Plasmid

    #24204

    Depositor

    David Rimm

    Insert

    beta catenin (CTNNB1 Human)
    

    Use

    Tags

    FLAG

    Expression

    Mammalian

    Mutation

    S33A, S37A, T41A,S45A

    Promoter

    CMV

    Available Since

    March 9, 2010

    Availability

    Academic Institutions and Nonprofits only

    

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19. pAAV-hSyn-GRAB-rDA3mut

    Plasmid

    #208706

    Purpose

    Expresses the genetically-encoded fluorescent dopamine (DA) control sensor GRAB_rDA3mut in neurons

    Depositor

    Yulong Li

    Article

    Zhuo et al Nat Methods. 2023 Nov 30. doi: 10.1038/s

    Insert

    GPCR activation based dopamine (DA) control sensor GRAB_rDA3mut
    

    Use

    AAV

    Tags

    Expression

    Mutation

    Promoter

    hSyn

    Available Since

    Oct. 26, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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20. pAAV-hSyn-GRAB_r5-HTmut

    Plasmid

    #208720

    Purpose

    Expresses the red 5-HT sensor GRAB_r5-HTmut in neurons

    Depositor

    Yulong Li

    Article

    Deng et al bioRxiv 2023.05.27.542566

    Insert

    Red fluorescent 5-HT sensor GRAB_r5-HTmut
    

    Use

    AAV

    Tags

    Expression

    Mutation

    Promoter

    hSyn

    Available Since

    Oct. 24, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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