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Showing: 5721 - 5740 of 5873 results

  2. pAAV-SCP1-dSa VPR mini.-2X snRP-1 Neurog2

    Plasmid
    #99694
    Purpose
    Expresses dSa Cas9 fused to optimized combination of truncated activation domains from SCP1 promoter with dual snRP1 poly adenylation signal, and Sa sgRNA for Actc1, vector allows for strong activation of mouse Actc1, can be packaged and delivered as AAV
    Depositor
    George Church
    Article
    Vora et al bioRxiv 2018. 298620
    Insert
    dCas9 and gRNA targeting Actc1 (gRNA: GGTATATAAGGGGTTTTAAG) (Actc1 Synthetic, Mouse)
    Use
    AAV and CRISPR
    Tags
    VPR mini
    Mutation
    dead Cas9
    Available Since
    Jan. 16, 2020
    Availability
    Academic Institutions and Nonprofits only
    99694-plasmid-map-sequence-id-194587

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  11. pKlab1157-HBEGF-2a-3xFLAG-BRCA1(full-length)-P1749S-2a-mRuby3-HBBIVS2-WPRE

    Plasmid
    #248997
    Purpose
    This plasmid expresses the BRCA1 sequence with P1749S mutation, the construct includes a HBBIVS2 intron sequence at the 3' end of the mRuby sequence to improve the stable integration into cell lines
    Depositor
    Georgios Karras
    Article
    Gracia et al Mol Cell. 2025 Nov 19:S1097-2765(25)0086
    Insert
    BRCA1 (BRCA1 Human)
    Use
    CRISPR
    Tags
    3x-FLAG-V5
    Mutation
    P1749S
    Available Since
    Jan. 21, 2026
    Availability
    Academic Institutions and Nonprofits only
    248997-plasmid-map-sequence-id-495753

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  12. pKlab1158-HBEGF-2a-3xFLAG-BRCA1(full-length)-R1699Q-2a-mRuby3-HBBIVS2-WPRE

    Plasmid
    #248998
    Purpose
    This plasmid expresses the BRCA1 sequence with R1699Q mutation, the construct includes a HBBIVS2 intron sequence at the 3' end of the mRuby sequence to improve the stable integration into cell lines
    Depositor
    Georgios Karras
    Article
    Gracia et al Mol Cell. 2025 Nov 19:S1097-2765(25)0086
    Insert
    BRCA1 (BRCA1 Human)
    Use
    CRISPR
    Tags
    3x-FLAG-V5
    Mutation
    R1699Q
    Available Since
    Jan. 21, 2026
    Availability
    Academic Institutions and Nonprofits only
    248998-plasmid-map-sequence-id-495728

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  13. pKlab1159-HBEGF-2a-3xFLAG-BRCA1(full-length)-R1699W-2a-mRuby3-HBBIVS2-WPRE

    Plasmid
    #248999
    Purpose
    This plasmid expresses the BRCA1 sequence with R1699W mutation, the construct includes a HBBIVS2 intron sequence at the 3' end of the mRuby sequence to improve the stable integration into cell lines
    Depositor
    Georgios Karras
    Article
    Gracia et al Mol Cell. 2025 Nov 19:S1097-2765(25)0086
    Insert
    BRCA1 (BRCA1 Human)
    Use
    CRISPR
    Tags
    3x-FLAG-V5
    Mutation
    R1699W
    Available Since
    Jan. 21, 2026
    Availability
    Academic Institutions and Nonprofits only
    248999-plasmid-map-sequence-id-495730

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  14. pKlab1160-HBEGF-2a-3xFLAG-BRCA1(full-length)-S1655F-2a-mRuby3-HBBIVS2-WPRE

    Plasmid
    #249000
    Purpose
    This plasmid expresses the BRCA1 sequence with S1655F mutation, the construct includes a HBBIVS2 intron sequence at the 3' end of the mRuby sequence to improve the stable integration into cell lines
    Depositor
    Georgios Karras
    Article
    Gracia et al Mol Cell. 2025 Nov 19:S1097-2765(25)0086
    Insert
    BRCA1 (BRCA1 Human)
    Use
    CRISPR
    Tags
    3x-FLAG-V5
    Mutation
    S1655F
    Available Since
    Jan. 21, 2026
    Availability
    Academic Institutions and Nonprofits only
    249000-plasmid-map-sequence-id-495994

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  15. pKlab1161-HBEGF-2a-3xFLAG-BRCA1(full-length)-V1736A-2a-mRuby3-HBBIVS2-WPRE

    Plasmid
    #249001
    Purpose
    This plasmid expresses the BRCA1 sequence with V1736A mutation, the construct includes a HBBIVS2 intron sequence at the 3' end of the mRuby sequence to improve the stable integration into cell lines
    Depositor
    Georgios Karras
    Article
    Gracia et al Mol Cell. 2025 Nov 19:S1097-2765(25)0086
    Insert
    BRCA1 (BRCA1 Human)
    Use
    CRISPR
    Tags
    3x-FLAG-V5
    Mutation
    V1736A
    Available Since
    Jan. 21, 2026
    Availability
    Academic Institutions and Nonprofits only
    249001-plasmid-map-sequence-id-495997

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  16. pKlab1069-HBEGF-2a-3xFLAG-BRCA1(full-length)-A1708V-2a-mRuby3-HBBIVS2-WPRE

    Plasmid
    #248989
    Purpose
    This plasmid expresses the BRCA1 sequence with A1708V mutation, the construct includes a HBBIVS2 intron sequence at the 3' end of the mRuby sequence to improve the stable integration into cell lines
    Depositor
    Georgios Karras
    Article
    Gracia et al Mol Cell. 2025 Nov 19:S1097-2765(25)0086
    Insert
    BRCA1 (BRCA1 Human)
    Use
    CRISPR
    Tags
    3x-FLAG-V5
    Mutation
    A1708V
    Available Since
    Jan. 21, 2026
    Availability
    Academic Institutions and Nonprofits only
    248989-plasmid-map-sequence-id-495734

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  17. pKlab1066-HBEGF-2a-3xFLAG-BRCA1(full-length)-L1705R-2a-mRuby3-HBBIVS2-WPRE

    Plasmid
    #248990
    Purpose
    This plasmid expresses the BRCA1 sequence with L1705R mutation, the construct includes a HBBIVS2 intron sequence at the 3' end of the mRuby sequence to improve the stable integration into cell lines
    Depositor
    Georgios Karras
    Article
    Gracia et al Mol Cell. 2025 Nov 19:S1097-2765(25)0086
    Insert
    BRCA1 (BRCA1 Human)
    Use
    CRISPR
    Tags
    3x-FLAG-V5
    Mutation
    L1705R
    Available Since
    Jan. 21, 2026
    Availability
    Academic Institutions and Nonprofits only
    248990-plasmid-map-sequence-id-495976

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  18. pKlab1070-HBEGF-2a-3xFLAG-BRCA1(full-length)-Y1845D-2a-mRuby3-HBBIVS2-WPRE

    Plasmid
    #248991
    Purpose
    This plasmid expresses the BRCA1 sequence with Y1845D mutation, the construct includes a HBBIVS2 intron sequence at the 3' end of the mRuby sequence to improve the stable integration into cell lines
    Depositor
    Georgios Karras
    Article
    Gracia et al Mol Cell. 2025 Nov 19:S1097-2765(25)0086
    Insert
    BRCA1 (BRCA1 Human)
    Use
    CRISPR
    Tags
    3x-FLAG-V5
    Mutation
    Y1845D
    Available Since
    Jan. 21, 2026
    Availability
    Academic Institutions and Nonprofits only
    248991-plasmid-map-sequence-id-495978

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  19. pKlab1067-HBEGF-2a-3xFLAG-BRCA1(full-length)-S1715R-2a-mRuby3-HBBIVS2-WPRE

    Plasmid
    #248992
    Purpose
    This plasmid expresses the BRCA1 sequence with S1715R mutation, the construct includes a HBBIVS2 intron sequence at the 3' end of the mRuby sequence to improve the stable integration into cell lines
    Depositor
    Georgios Karras
    Article
    Gracia et al Mol Cell. 2025 Nov 19:S1097-2765(25)0086
    Insert
    BRCA1 (BRCA1 Human)
    Use
    CRISPR
    Tags
    3x-FLAG-V5
    Mutation
    S1715R
    Available Since
    Jan. 21, 2026
    Availability
    Academic Institutions and Nonprofits only
    248992-plasmid-map-sequence-id-496009

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  20. pKlab1153-HBEGF-2a-3xFLAG-BRCA1(full-length)-D1692N-2a-mRuby3-HBBIVS2-WPRE

    Plasmid
    #248993
    Purpose
    This plasmid expresses the BRCA1 sequence with D1692N mutation, the construct includes a HBBIVS2 intron sequence at the 3' end of the mRuby sequence to improve the stable integration into cell lines
    Depositor
    Georgios Karras
    Article
    Gracia et al Mol Cell. 2025 Nov 19:S1097-2765(25)0086
    Insert
    BRCA1 (BRCA1 Human)
    Use
    CRISPR
    Tags
    3x-FLAG-V5
    Mutation
    D1692N
    Available Since
    Jan. 21, 2026
    Availability
    Academic Institutions and Nonprofits only
    248993-plasmid-map-sequence-id-495723

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Showing: 5721 - 5740 of 5873 results