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Showing: 901 - 930 of 1018 results

  1. Nav1.5_1-2linker411-717_PPSYtoAASA1960-1996

    Plasmid
    #187732
    Purpose
    Express a chimera of the Nav1.5 linker between the first and second transmembrane domain with the motif surrounding PPSY; residues 1974-1977 PPSY mutated to AASA
    Depositor
    Sandra Gabelli
    Article
    Wright et al J Biol Chem. 2024 Mar;300(3):105715. doi
    Insert
    Nav1.5 1,2linker residues 411-717 and Nav1.5 residues 1960-1996 PPSY mutated to AASA (SCN5A Human)
    Use
    Tags
    His-TEV
    Expression
    Bacterial
    Mutation
    deletion of residues 1-410 and 718-1959 and 1997-…
    Promoter
    Available since
    Oct. 24, 2024
    Availability
    Academic Institutions and Nonprofits only
    187732-plasmid-map-sequence-id-372456

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  3. KRD22_HBA1(HBA1reg-HBB-longHAs)

    Plasmid
    #232403
    Purpose
    AAV production plasmid for HBA1 long HAs vector from Figs. 3-6 that mediates HDR at HBA1 locus using HBA1 sg5 gRNA. HBB gene includes introns; HBA1 UTRs flank full HBA1-2A-YFP cassette. HAs are ~900bp
    Depositor
    Kyle Cromer, Matthew Porteus
    Article
    Cromer et al Nat Med. 2021 Apr;27(4):677-687. doi: 10
    Inserts
    Hemoglobin Subunit Alpha 1 (HBA1 Human)
    Human Hemoglobin Subunit Beta (HBB Human)
    Use
    Tags
    Expression
    Mammalian
    Mutation
    Promoter
    Available since
    April 18, 2025
    Availability
    Academic Institutions and Nonprofits only
    232403-plasmid-map-sequence-id-466149

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  4. pCG_SARS-CoV2 NSP7/bat-CoV RaTG13 C-V5-tag

    Plasmid
    #179974
    Purpose
    Mammalian expression vector for SARS-CoV-2 Nsp7 or bat RaTG13 Nsp7, V5-tagged (SARS-CoV-2 Nsp7 and RaTG13 Nsp7 have the same amino acid sequence and codon optimized sequence).
    Depositor
    Konstantin Sparrer
    Article
    Hayn et al Cell Rep. 2021 May 18;35(7):109126.
    Insert
    SARS-CoV-2 Nsp7 (ORF1ab Synthetic)
    Use
    Tags
    Expression
    Mammalian
    Mutation
    human codon-optimized
    Promoter
    Available since
    Feb. 7, 2022
    Availability
    Academic Institutions and Nonprofits only
    179974-plasmid-map-sequence-id-353863

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  5. pSG5-hPXR-K62Q

    Plasmid
    #67766
    Purpose
    Expression hPXR mutant K62Q in Mammalian Cells
    Depositor
    Sridhar Mani
    Insert
    human pregnane X receptor (PXR) (NR1I2 Human)
    Use
    Tags
    Expression
    Mammalian
    Mutation
    lysine 62 to Glutamine
    Promoter
    SV40
    Available since
    July 22, 2015
    Availability
    Academic Institutions and Nonprofits only
    67766-plasmid-map-sequence-id-119289

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  6. pSG5-hPXR-K62R

    Plasmid
    #67765
    Purpose
    Expression hPXR mutant K62R in Mammalian Cells
    Depositor
    Sridhar Mani
    Insert
    human pregnane X receptor (PXR) (NR1I2 Human)
    Use
    Tags
    Expression
    Mammalian
    Mutation
    lysine 62 to Arginine
    Promoter
    SV40
    Available since
    July 22, 2015
    Availability
    Academic Institutions and Nonprofits only
    67765-plasmid-map-sequence-id-119285

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  7. pCMX-hPXR-K62R

    Plasmid
    #67768
    Purpose
    Expression hPXR mutant K62R in Mammalian Cells
    Depositor
    Sridhar Mani
    Insert
    human pregnane X receptor (PXR) (NR1I2 Human)
    Use
    Tags
    Expression
    Mammalian
    Mutation
    lysine 62 to Arginine
    Promoter
    CMV
    Available since
    July 22, 2015
    Availability
    Academic Institutions and Nonprofits only

  8. pCMX-hPXR-K62Q

    Plasmid
    #67767
    Purpose
    Expression hPXR mutant K62Q in Mammalian Cells
    Depositor
    Sridhar Mani
    Insert
    human pregnane X receptor (PXR) (NR1I2 Human)
    Use
    Tags
    Expression
    Mammalian
    Mutation
    lysine 62 to Glutamine
    Promoter
    CMV
    Available since
    July 22, 2015
    Availability
    Academic Institutions and Nonprofits only

  10. pCDNA3-hPXR-FL-T248E

    Plasmid
    #41617
    Depositor
    Sridhar Mani
    Insert
    hPXR-FL-T248E (NR1I2 Human)
    Use
    Tags
    Expression
    Mammalian
    Mutation
    N10D and T248E
    Promoter
    CMV
    Available since
    March 11, 2013
    Availability
    Academic Institutions and Nonprofits only

  11. 8061-E48

    Plasmid
    #234285
    Purpose
    Gateway ORF Entry clone of mouse Amhr2 with stop codon (for native or N-terminal fusions)
    Depositor
    Dominic Esposito
    Insert
    Amhr2 (Amhr2 Mouse)
    Use
    Gateway entry clone
    Tags
    Expression
    Mutation
    Promoter
    Available since
    May 5, 2025
    Availability
    Academic Institutions and Nonprofits only
    234285-plasmid-map-sequence-id-469782

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  12. pCDNA3-hPXR-FL-K277Q

    Plasmid
    #41618
    Depositor
    Sridhar Mani
    Insert
    hPXR-FL-K277Q (NR1I2 Human)
    Use
    Tags
    Expression
    Mammalian
    Mutation
    N10D and K277Q
    Promoter
    CMV
    Available since
    March 11, 2013
    Availability
    Academic Institutions and Nonprofits only

  19. ACVR1A

    Plasmid
    #74650
    Purpose
    Baculovirus expression for structure determination; may not be full ORF
    Depositor
    Nicola Burgess-Brown
    Insert
    ACVR1A (ACVR1 Human)
    Use
    Baculovirus
    Tags
    His-6-TEV
    Expression
    Mutation
    R206H
    Promoter
    PH
    Available since
    April 21, 2016
    Availability
    Academic Institutions and Nonprofits only

  20. pSH-hPXR-LBD-T248E

    Plasmid
    #41619
    Depositor
    Sridhar Mani
    Insert
    hPXR-LBD-T248E (NR1I2 Human)
    Use
    Tags
    Expression
    Mammalian
    Mutation
    contains human PXR ligand binding domain (LBD, aa…
    Promoter
    pEN1 (chimeric HIV-1 LTR enhancer and HTLV-I LTR …
    Available since
    April 24, 2013
    Availability
    Academic Institutions and Nonprofits only

  21. pSH-hPXR-LBD-K277Q

    Plasmid
    #41620
    Depositor
    Sridhar Mani
    Insert
    hPXR-LBD-K277Q (NR1I2 Human)
    Use
    Tags
    Expression
    Mammalian
    Mutation
    contains human PXR ligand binding domain (LBD, aa…
    Promoter
    pEN1 (chimeric HIV-1 LTR enhancer and HTLV-I LTR …
    Available since
    May 31, 2013
    Availability
    Academic Institutions and Nonprofits only

  22. ACVR1

    Plasmid
    #39177
    Purpose
    Baculovirus expression for structure determination; may not be full ORF
    Depositor
    Nicola Burgess-Brown
    Insert
    ACVR1 (ACVR1 Human)
    Use
    Baculovirus expression
    Tags
    His Tev
    Expression
    Mutation
    Activating mutation Q207D
    Promoter
    Available since
    March 18, 2013
    Availability
    Academic Institutions and Nonprofits only

  23. ACVR1 (ACVR1Z-c041)

    Plasmid
    #110269
    Purpose
    Baculovirus expression for structure determination; may not be full ORF
    Depositor
    Nicola Burgess-Brown
    Insert
    ACVR1 (ACVR1 Human)
    Use
    Tags
    His-TEV
    Expression
    Insect
    Mutation
    Promoter
    polyhedrin promoter
    Available since
    June 7, 2018
    Availability
    Academic Institutions and Nonprofits only
    110269-plasmid-map-sequence-id-212278

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  28. Donor_eGP2AP_RC

    Plasmid
    #133784
    Purpose
    Library reporter vector/integration vector. Contains library cloning sites MluI and SpeI upstream of a terminator and downstream of a BxB1 attB site. Library integration occurs through BxB1 site.
    Depositor
    Sriram Kosuri
    Article
    Davis et al Cell Syst. 2020 Jul 22;11(1):75-85.e7. d
    Type
    Empty backbone
    Use
    Tags
    eGFP-P2A-Puro
    Expression
    Mammalian
    Mutation
    Promoter
    Available since
    June 30, 2020
    Availability
    Academic Institutions and Nonprofits only
    133784-plasmid-map-sequence-id-274492

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Showing: 901 - 930 of 1018 results