We narrowed to 708 results for: th

1. MEK1C218C222

   Plasmid

   #164640

   Purpose

   Bacterial expression plasmid for His6-MEK1C218C222

   Depositor

   Ben Davis

   Article

   Lai et al Cell. 2021 Apr 27. pii: S0092-8674(21)00

   Insert

   mitogen-activated protein kinase kinase 1 (MAP2K1 Human)
   

   Tags

   His6-tag

   Expression

   Bacterial

   Mutation

   G(-19)F/S218C/S222C/C277S/C376S

   Promoter

   T7

   Available Since

   May 5, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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2. pU6_rd6_pegRNA_(PP7-C4-Q1)

   Plasmid

   #232433

   Purpose

   pegRNA with optimized 3' modifications to correct the rd6 mutation

   Depositor

   Gil Westmeyer

   Article

   Geilenkeuser et al Cell. 2025 May 15;188(10):2637-2655.e31.

   Insert

   3'-PP7-tagged pegRNA for rd6 correction driven by human U6 promoter
   

   Use

   CRISPR

   Promoter

   U6

   Available Since

   April 10, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

3. pU6_empty-sgRNA(PP7)

   Plasmid

   #232432

   Purpose

   empty gRNA backbone which contains the PP7 aptamer in the scaffold tetraloop

   Depositor

   Gil Westmeyer

   Article

   Geilenkeuser et al Cell. 2025 May 15;188(10):2637-2655.e31.

   Insert

   PP7-tagged sgRNA scaffold driven by human U6 promoter
   

   Use

   CRISPR

   Promoter

   U6

   Available Since

   April 10, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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4. PCR4-Shh::lacZ-H11

   Plasmid

   #139098

   Purpose

   enSERT LacZ reporter vector for site-specific integration into the H11 locus (contains Shh minimal promoter)

   Depositor

   Len Pennacchio

   Article

   Kvon et al Cell. 2020 Mar 6. pii: S0092-8674(20)302

   Type

   Empty backbone

   Use

   CRISPR and Mouse Targeting

   Expression

   Mammalian

   Promoter

   Shh

   Available Since

   March 12, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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5. pU6_HEK3_nsgRNA(PP7)

   Plasmid

   #232444

   Purpose

   nsgRNA for PE3 facilitation of a +1 T to A prime edit on the HEK3 locus, contains a PP7 in the scaffold tetraloop

   Depositor

   Gil Westmeyer

   Article

   Geilenkeuser et al Cell. 2025 May 15;188(10):2637-2655.e31.

   Insert

   PP7-tagged nicking gRNA (PE3) for HEK3+1t>a edit driven by human U6 promoter
   

   Use

   CRISPR

   Promoter

   U6

   Available Since

   April 10, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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6. PCR4-Hsp68::lacZ-H11

   Plasmid

   #139099

   Purpose

   enSERT LacZ reporter vector for site-specific integration into the H11 locus (contains Hsp68 minimal promoter)

   Depositor

   Len Pennacchio

   Article

   Kvon et al Cell. 2020 Mar 6. pii: S0092-8674(20)302

   Type

   Empty backbone

   Use

   CRISPR and Mouse Targeting

   Expression

   Mammalian

   Promoter

   Hsp68

   Available Since

   March 12, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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7. pBABEpuro-gateway

   Plasmid

   #51070

   Purpose

   gateway adapted mammalian expression vector

   Depositor

   Matthew Meyerson

   Article

   Greulich et al Proc Natl Acad Sci U S A. 2012 Sep 4;109

   Type

   Empty backbone

   Use

   Retroviral

   Expression

   Mammalian

   Promoter

   SV40

   Available Since

   Feb. 25, 2014

   Availability

   Academic Institutions and Nonprofits only

   

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8. p-Tet-O-RUNX1T1-Puro

   Plasmid

   #221666

   Purpose

   Expresses RUNX1T1 in mammalian cells

   Depositor

   Vanessa Hall

   Article

   Bergmann et al Front Cell Dev Biol. 2022 Aug 15;10:9765

   Insert

   RUNX1T1 (RUNX1T1 Human)
   

   Use

   Lentiviral

   Available Since

   July 25, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

9. pU6_rd6_nsgRNA(PP7)

   Plasmid

   #232434

   Purpose

   nsgRNA for PE3b correction of the rd6 mutation, contains a PP7 in the scaffold tetraloop

   Depositor

   Gil Westmeyer

   Article

   Geilenkeuser et al Cell. 2025 May 15;188(10):2637-2655.e31.

   Insert

   PP7-tagged nicking gRNA (PE3b) for rd6 correction driven by human U6 promoter
   

   Use

   CRISPR

   Promoter

   U6

   Available Since

   April 10, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. pU6_rd12_pegRNA_(PP7-C4-Q1)

    Plasmid

    #232435

    Purpose

    pegRNA with optimized 3' modifications to correct the rd12 mutation

    Depositor

    Gil Westmeyer

    Article

    Geilenkeuser et al Cell. 2025 May 15;188(10):2637-2655.e31.

    Insert

    3'-PP7-tagged pegRNA for rd12 correction driven by human U6 promoter
    

    Use

    CRISPR

    Promoter

    U6

    Available Since

    April 10, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

11. pU6_rd12_nsgRNA(PP7)

    Plasmid

    #232436

    Purpose

    nsgRNA for PE3b correction of the rd12 mutation, contains a PP7 in the scaffold tetraloop

    Depositor

    Gil Westmeyer

    Article

    Geilenkeuser et al Cell. 2025 May 15;188(10):2637-2655.e31.

    Insert

    PP7-tagged nicking gRNA (PE3b) for rd12 correction driven by human U6 promoter
    

    Use

    CRISPR

    Promoter

    U6

    Available Since

    April 10, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. R979-X58-008: Hs.KRAS4b(1-188)

    Plasmid

    #159691

    Purpose

    Baculovirus protein expression of KRAS4b (1-188)

    Depositor

    Dominic Esposito

    Article

    Dharmaiah et al Sci Rep. 2019 Jul 19;9(1):10512. doi: 10

    Insert

    Hs.KRAS4b(1-188) (KRAS Human)
    

    Expression

    Insect

    Available Since

    Sept. 29, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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13. R717-X61-566: His6-MBP-tev-Hs.RAF1(52-192)

    Plasmid

    #159687

    Purpose

    E. coli protein expression of His6-MBP-tev-Hs.RAF1(52-192)

    Depositor

    Dominic Esposito

    Article

    Tran et al Nat Commun. 2021 Feb 19;12(1):1176. doi:

    Insert

    His6-MBP-tev-Hs.RAF1(52-192) (RAF1 Human)
    

    Tags

    His6-MBP-tev

    Expression

    Bacterial

    Available Since

    Sept. 29, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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14. ERK1C202

    Plasmid

    #164647

    Purpose

    Bacterial expression plasmid for His6-ERK1C202

    Depositor

    Ben Davis

    Article

    Lai et al Cell. 2021 Apr 27. pii: S0092-8674(21)00

    Insert

    ERK1C202 (MAPK1 Human)
    

    Tags

    His6-tag

    Expression

    Bacterial

    Mutation

    K71R/C82S/C144S/C178S/C183S/T202C/C271S

    Promoter

    T7

    Available Since

    May 5, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. ERK1C82C202

    Plasmid

    #164650

    Purpose

    Bacterial expression plasmid for His6-ERK1C82C202

    Depositor

    Ben Davis

    Article

    Lai et al Cell. 2021 Apr 27. pii: S0092-8674(21)00

    Insert

    ERK1C82C202 (MAPK1 Human)
    

    Tags

    His6-tag

    Expression

    Bacterial

    Mutation

    K71R/C144S/C178S/C183S/T202C/C271S

    Promoter

    T7

    Available Since

    May 5, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. p-Tet-O-EYA2-Puro

    Plasmid

    #221669

    Purpose

    Expresses EYA2 in mammalian cells

    Depositor

    Vanessa Hall

    Article

    Bergmann et al Front Cell Dev Biol. 2022 Aug 15;10:9765

    Insert

    EYA2 (EYA2 Human)
    

    Use

    Lentiviral

    Available Since

    July 25, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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17. p-Tet-O-Foxp1A-Puro

    Plasmid

    #221665

    Purpose

    Expresses Foxp1A in mammalian cells

    Depositor

    Vanessa Hall

    Article

    Bergmann et al Front Cell Dev Biol. 2022 Aug 15;10:9765

    Insert

    Foxp1A (Foxp1 Mouse)
    

    Use

    Lentiviral

    Available Since

    July 23, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. Δ1-60MEK1C222

    Plasmid

    #164641

    Purpose

    Bacterial expression plasmid for His6-ΔMEK1C222

    Depositor

    Ben Davis

    Article

    Lai et al Cell. 2021 Apr 27. pii: S0092-8674(21)00

    Insert

    N-terminal truncated mitogen-activated protein kinase kinase 1 (MAP2K1 Human)
    

    Tags

    His6-tag

    Expression

    Bacterial

    Mutation

    S222C/C277S/C376S; residues 1-60 at N-terminus we…

    Promoter

    T7

    Available Since

    May 5, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. Δ1-60MEK1C218

    Plasmid

    #164643

    Purpose

    Bacterial expression plasmid for His6-ΔMEK1C218

    Depositor

    Ben Davis

    Article

    Lai et al Cell. 2021 Apr 27. pii: S0092-8674(21)00

    Insert

    N-terminal truncated mitogen-activated protein kinase kinase 1 (MAP2K1 Human)
    

    Tags

    His6-tag

    Expression

    Bacterial

    Mutation

    S218C/C277S/C376S; residues 1-60 at N-terminus we…

    Promoter

    T7

    Available Since

    May 5, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. Δ1-60MEK1C218C222

    Plasmid

    #164645

    Purpose

    Bacterial expression plasmid for His6-ΔMEK1C218C222

    Depositor

    Ben Davis

    Article

    Lai et al Cell. 2021 Apr 27. pii: S0092-8674(21)00

    Insert

    N-terminal truncated mitogen-activated protein kinase kinase 1 (MAP2K1 Human)
    

    Tags

    His6-tag

    Expression

    Bacterial

    Mutation

    S218C/S222C/C277S/C376S; residues 1-60 at N-termi…

    Promoter

    T7

    Available Since

    May 5, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge