We narrowed to 15,831 results for: grna

1. pX458-AAVS1-sg

   Plasmid

   #194721

   Purpose

   px458 with guide RNA that target hAAVS1

   Depositor

   Rudolf Jaenisch

   Article

   Haiting et al bioRxiv

   Insert

   Cas9 (AAVS1 Streptococcus pyogenes)
   

   Use

   CRISPR

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available Since

   Jan. 10, 2023

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

2. pX459-puro-hGSDMD

   Plasmid

   #185377

   Purpose

   For mammalian expression of guide RNA: CGCGCCAGACGCGCCACCCT that targets human GSDMD (Gasdermin D)

   Depositor

   Ayaz Najafov

   Insert

   GSDMD (GSDMD Human)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   WT

   Promoter

   Available Since

   June 6, 2022

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

3. LT3GEPIR-HDACshRNA

   Plasmid

   #220573

   Purpose

   To inducibly knockdown HDAC3 expression

   Depositor

   Sean Lee

   Insert

   HDAC3 shRNA (HDAC3 Human)
   

   Use

   Lentiviral

   Tags

   Expression

   Mutation

   Promoter

   TRE3G (TetOP) promoter

   Available Since

   July 3, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

4. LT3GEPIR-NEK1shRNA2

   Plasmid

   #220539

   Purpose

   To inducibly knockdown NEK1 expression

   Depositor

   Sean Lee

   Insert

   NEK1 shRNA2 (NEK1 Human)
   

   Use

   Lentiviral

   Tags

   Expression

   Mutation

   Promoter

   TRE3G (TetOP) promoter

   Available Since

   July 31, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

5. ipUSEPR-sg-Hs-TMPRSS2-A6

   Plasmid

   #188690

   Purpose

   sgRNA

   Depositor

   Lewis Cantley

   Insert

   sgTMPRSS2 (TMPRSS2 Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mutation

   WT

   Promoter

   Available Since

   Oct. 21, 2022

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

6. pAIO-Ef1a-PE2-GFP:KCNQ2-C201R

   Plasmid

   #185060

   Purpose

   Ef1a driven PE2 plasmid with pegRNA for editing C201R mutation in KCNQ2 gene. See Addgene plasmid #184445

   Depositor

   Bobby Koeleman

   Insert

   U6:pegRNA:scaffold:PBS+RT template
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   U6

   Available Since

   Nov. 7, 2022

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

7. pAAV-CMV-FLEX-SaCas9-U6-sgSlc6a3

   Plasmid

   #159902

   Purpose

   Mutagenesis of Slc6a3

   Depositor

   Larry Zweifel

   Insert

   Slc6a3 (Slc6a3 Mouse)
   

   Use

   AAV, CRISPR, and Mouse Targeting

   Tags

   Expression

   Mutation

   Promoter

   Available Since

   Nov. 16, 2020

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

8. pSpCas9_mouse_Adar1_ccB

   Plasmid

   #158122

   Purpose

   deletion mAdar1

   Depositor

   Emanuela Felley-Bosco

   Insert

   Adar1 (Adar Mouse)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available Since

   Oct. 4, 2022

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

9. pSpCas9_mouse_Adar1_ccA

   Plasmid

   #158120

   Purpose

   deletion mAdar1

   Depositor

   Emanuela Felley-Bosco

   Insert

   Adar1 (Adar Mouse)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available Since

   Oct. 4, 2022

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. pResQ shFEN3 3XF-FEN1 wt

    Plasmid

    #17752

    Depositor

    Sheila Stewart

    Insert

    Flap Endonuclease I (FEN1 Human)
    

    Use

    Lentiviral and RNAi

    Tags

    Triple Flag

    Expression

    Mammalian

    Mutation

    Promoter

    Available Since

    April 29, 2008

    Availability

    Academic Institutions and Nonprofits only

11. pX459-puro-hMYC

    Plasmid

    #185376

    Purpose

    For mammalian expression of guide RNA: TGCTGCCAAGAGGGTCAAGT that targets human MYC

    Depositor

    Ayaz Najafov

    Insert

    MYC (MYC Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    WT

    Promoter

    Available Since

    June 6, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. pX459-puro-hPKAalpha

    Plasmid

    #185379

    Purpose

    For mammalian expression of guide RNA: caccgTTTGAACGAATCAAGACCCT that targets human PKA subunit alpha

    Depositor

    Ayaz Najafov

    Insert

    PRKACA (PRKACA Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    WT

    Promoter

    Available Since

    June 6, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

13. ipUSEPR-sg-Hs-BCL2L1-A1

    Plasmid

    #188692

    Purpose

    sgRNA

    Depositor

    Lewis Cantley

    Insert

    sgBCL2L1 (BCL2L1 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mutation

    WT

    Promoter

    Available Since

    Oct. 20, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. pAAV-CMV-FLEXfrt-SaCas9-U6-sgNtsr1

    Plasmid

    #159910

    Purpose

    Mutagenesis of Ntsr1

    Depositor

    Larry Zweifel

    Insert

    Ntsr1 (Ntsr1 Mouse)
    

    Use

    AAV, CRISPR, and Mouse Targeting

    Tags

    Expression

    Mutation

    Promoter

    Available Since

    Nov. 16, 2020

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. pMV_AA101

    Plasmid

    #245323

    Purpose

    Cas9 CRISPRa positive control guide; targets CD274

    Depositor

    David Root, John Doench

    Insert

    sgRNA CD274 (CD274 Synthetic)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    None

    Promoter

    Available Since

    Oct. 2, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. pRDB_510

    Plasmid

    #245337

    Purpose

    Cas9 CBE positive control guide; targets CD274

    Depositor

    David Root, John Doench

    Insert

    sgRNA CD274 (CD274 Synthetic)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    None

    Promoter

    Available Since

    Oct. 2, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. pRDB_509

    Plasmid

    #245336

    Purpose

    Cas9 ABE positive control guide; targets CD274

    Depositor

    David Root, John Doench

    Insert

    sgRNA CD274 (CD274 Synthetic)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    None

    Promoter

    Available Since

    Oct. 2, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. pRDB_248

    Plasmid

    #245335

    Purpose

    Cas12a CRISPRko positive control guide; targets CD63

    Depositor

    David Root, John Doench

    Insert

    sgRNA CD63 (CD63 Synthetic)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    None

    Promoter

    Available Since

    Oct. 2, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. pLenti-shDLD #1

    Plasmid

    #242706

    Purpose

    shRNA knockdown human DLD gene

    Depositor

    Xingguo Zhu

    Insert

    DLD (DLD Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available Since

    Oct. 1, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. pLenti-shDLD #2

    Plasmid

    #242707

    Purpose

    shRNA knockdown human DLD gene

    Depositor

    Xingguo Zhu

    Insert

    DLD (DLD Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available Since

    Oct. 1, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

21. pQdCas12a.sggfp(A)

    Plasmid

    #236038

    Purpose

    The plasmid pQdCas12a.sggfp(A) expresses the dCas12a endonuclease and the sgRNA (design A) targeting the gfp gene.

    Depositor

    Radhakrishnan Mahadevan

    Insert

    quorum sensing cassette luxI, luxR, and the LuxR-dependent promoter pLuxI , dCas12a and sgRNA design (A) of gfp gene
    

    Use

    CRISPR

    Tags

    Expression

    Mutation

    Promoter

    quorum sensing promoter

    Available Since

    April 24, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

22. LT3GEPIR-NEK1shRNA1

    Plasmid

    #220538

    Purpose

    To inducibly knockdown NEK1 expression

    Depositor

    Sean Lee

    Insert

    NEK1 shRNA1 (NEK1 Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    TRE3G (TetOP) promoter

    Available Since

    Nov. 20, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

23. LT3GEPIR-CDK1shRNA2

    Plasmid

    #220570

    Purpose

    To inducibly knockdown CDK1 expression

    Depositor

    Sean Lee

    Insert

    CDK1 shRNA2 (CDK1 Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    TRE3G (TetOP) promoter

    Available Since

    July 3, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

24. pCFD3-dUG-DH1

    Plasmid

    #138963

    Purpose

    Used to edit the endogenous Drosophila kkv gene to encode a fluorescent Chitin Synthase.

    Depositor

    Paul Adler

    Article

    Adler et al bioRxiv 2020

    Insert

    DH1 oligo
    

    Use

    CRISPR

    Tags

    Expression

    Insect

    Mutation

    Promoter

    Available Since

    Sept. 27, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

25. pAAV-CMV-FLEXfrt-SaCas9-U6-sgNtsr1(guide_2)

    Plasmid

    #205417

    Purpose

    Mutagenesis of Ntsr1, second guide

    Depositor

    Larry Zweifel

    Insert

    Ntsr1 (Ntsr1 Mouse)
    

    Use

    AAV and CRISPR

    Tags

    Expression

    Mutation

    Promoter

    U6

    Available Since

    Sept. 21, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

26. ipUSEPR-sg-Hs-ACE2-A2

    Plasmid

    #188687

    Purpose

    sgRNA

    Depositor

    Lewis Cantley

    Insert

    sgACE2 (ACE2 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mutation

    WT

    Promoter

    Available Since

    Oct. 21, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

27. ipUSEPR-sg-Hs-ACE2-A4

    Plasmid

    #188688

    Purpose

    sgRNA

    Depositor

    Lewis Cantley

    Insert

    sgACE2 (ACE2 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mutation

    WT

    Promoter

    Available Since

    Oct. 21, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

28. ipUSEPR-sg-Hs-TMPRSS2-A5

    Plasmid

    #188689

    Purpose

    sgRNA

    Depositor

    Lewis Cantley

    Insert

    sgTMPRSS2 (TMPRSS2 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mutation

    WT

    Promoter

    Available Since

    Oct. 21, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

29. pSpCas9_mouse_Adar1_ccC

    Plasmid

    #158121

    Purpose

    deletion mAdar1

    Depositor

    Emanuela Felley-Bosco

    Insert

    Adar1 (Adar Mouse)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available Since

    Oct. 4, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

30. HCP4

    Plasmid

    #166106

    Purpose

    This plasmid encodes a Cas9 protein as well as two sgRNAs, one targets the center of Cyr1 and the other targets a non-coding region on chromosome X (location X1)

    Depositor

    Matthias Heinemann

    Insert

    Cyr1Del-sgRNA/X1-sgRNA (CYR1 Budding Yeast)
    

    Use

    CRISPR

    Tags

    Expression

    Yeast

    Mutation

    Promoter

    Available Since

    April 14, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge