We narrowed to 4,233 results for: gca

1. pLCHKOv3-CD46 Ex3_2-Lb

   Plasmid

   #209028

   Purpose

   Lentiviral vector expressing U6 driven hybrid guide (hgRNA) targeting human CD46 Exon 3 for deletion using SpCas9 and LbCas12a nucleases (CHyMErA system)

   Depositor

   Thomas Gonatopoulos-Pournatzis

   Article

   Xiao et al Mol Cell. 2024 Jul 11;84(13):2553-2572.e

   Insert

   hgRNA for deletion of CD46 Exon 3 with SpCas9 tracrRNAv1 & LbCas12a DR
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   U6

   Available since

   June 20, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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2. pLCHKOv3-CD46 Ex3_2-As

   Plasmid

   #209032

   Purpose

   Lentiviral vector expressing U6 driven hybrid guide (hgRNA) targeting human CD46 Exon 3 for deletion using SpCas9 and AsCas12a nucleases (CHyMErA system)

   Depositor

   Thomas Gonatopoulos-Pournatzis

   Article

   Xiao et al Mol Cell. 2024 Jul 11;84(13):2553-2572.e

   Insert

   hgRNA for deletion of CD46 Exon 3 with SpCas9 tracrRNAv1 & AsCas12a DR
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   U6

   Available since

   June 20, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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3. pLV-GG-hUbC-EBPF2-gRNA-RBMS3

   Plasmid

   #185557

   Purpose

   Lentiviral backbone with EBFP2 reporter and gRNA targeting RBMS3

   Depositor

   Andrew Wilson

   Article

   Werder et al Sci Adv. 2022 Jul 15;8(28):eabo6566. doi

   Insert

   RBMS3 gRNAs
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   Dec. 7, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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4. pU6-pegRNA-SNCA-A53T

   Plasmid

   #181738

   Purpose

   Transiently expressing a pegRNA to introduce SNCA-A53T mutation in human cells

   Depositor

   Dirk Hockemeyer

   Article

   Li et al Elife. 2022 Sep 7;11:e79208. doi: 10.755

   Insert

   Prime editing pegRNA for SNCA-A53T (SNCA Synthetic)
   

   Use

   CRISPR

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Human U6

   Available since

   Sept. 8, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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5. pAAV-hSyn-mCherry-Rorb sesRNA-2a-msFlag-2a-tTA2-WPRE

   Plasmid

   #239029

   Purpose

   Expression of mCherry, sesRNA in mammalian cells, with msFlag and tTA2 as efRNA.

   Depositor

   Josh Huang

   Article

   Qian et al Nature. 2022 Oct;610(7933):713-721. doi:

   Insert

   sesRNA for mouse Rorb (Rorb Mouse)
   

   Use

   AAV

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hSyn

   Available since

   May 14, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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6. pMVP-SEC24C-G220C

   Plasmid

   #231560

   Purpose

   pMVP expression vector for human SEC24C (G220C mutation, closed, resistant to sgSEC24C #1 and #2) (Blasticidin selection marker)

   Depositor

   Rizwan Haq

   Article

   Schiantarelli et al Cancer Cell. 2025 Feb 10;43(2):308-316.e

   Insert

   SEC24C (G220C) (SEC24C Human)
   

   Use

   Lentiviral

   Tags

   V5

   Expression

   Mammalian

   Mutation

   G220C, silent PAM mutations (G67 (GGG>GGA) and…

   Promoter

   CMV

   Available since

   Feb. 3, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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7. pMVP-SEC24C

   Plasmid

   #231559

   Purpose

   pMVP expression vector for human SEC24C (wild type, closed, resistant to sgSEC24C #1 and #2) (Blasticidin selection marker)

   Depositor

   Rizwan Haq

   Article

   Schiantarelli et al Cancer Cell. 2025 Feb 10;43(2):308-316.e

   Insert

   SEC24C (SEC24C Human)
   

   Use

   Lentiviral

   Tags

   V5

   Expression

   Mammalian

   Mutation

   silent PAM mutations (G67 (GGG>GGA) and A115 (…

   Promoter

   CMV

   Available since

   Jan. 30, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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8. pMVP-SEC24C-S107F

   Plasmid

   #231561

   Purpose

   pMVP expression vector for human SEC24C (S107F mutation, closesd, resistant to sgSEC24C #1 and #2) (Blasticidin selection marker)

   Depositor

   Rizwan Haq

   Article

   Schiantarelli et al Cancer Cell. 2025 Feb 10;43(2):308-316.e

   Insert

   SEC24C (S107F) (SEC24C Human)
   

   Use

   Lentiviral

   Tags

   V5

   Expression

   Mammalian

   Mutation

   S107F, silent PAM mutations (G67 (GGG>GGA) and…

   Promoter

   CMV

   Available since

   Jan. 30, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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9. pAAV CAG Barcode2

   Plasmid

   #229063

   Purpose

   Expression mapping

   Depositor

   Scott Sternson

   Insert

   CAG Barcode2
   

   Use

   AAV

   Tags

   Expression

   Mutation

   Promoter

   Available since

   Dec. 3, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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10. pAAV Syn Barcode19

    Plasmid

    #226196

    Purpose

    Expression mapping

    Depositor

    Scott Sternson

    Insert

    Syn Barcode19
    

    Use

    AAV

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Oct. 30, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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11. pAAV Syn Barcode22

    Plasmid

    #226193

    Purpose

    Expression mapping

    Depositor

    Scott Sternson

    Insert

    Syn Barcode22
    

    Use

    AAV

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Oct. 30, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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12. pCfb13201

    Plasmid

    #219876

    Purpose

    The base plasmid of TUNEYALI forTF11

    Depositor

    Irina Borodina

    Insert

    Contains gRNA targeting TF11 (YALI1_E11341g) and homologous arm matching TF11
    

    Use

    Tags

    Expression

    Yeast

    Mutation

    Promoter

    Available since

    June 4, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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13. pAAVS1-CAG-hCAS9-neo

    Plasmid

    #166026

    Purpose

    AAVS1 targeting vector carrying CAG-SpCas9-neo

    Depositor

    Kosuke Yusa

    Insert

    AAVS1-CAGCas9IRESneo
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    March 18, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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14. pICSL4723_ Rac4

    Plasmid

    #126884

    Purpose

    Genome editing of the wheat homolog of a susceptibility gene of O. sativa. Encodes wheat optimized Cas9 module, nptII resistance gene, and specific sgRNA modules on the binary plasmid pICSL4723.

    Depositor

    Sophien Kamoun

    Insert

    Wheat_live_Cas9
    

    Use

    CRISPR

    Tags

    Expression

    Mutation

    Promoter

    Available since

    July 24, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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15. pENTRY4_ Rac4

    Plasmid

    #126896

    Purpose

    Gateway pENTR-plasmid to generate a binary construct for genome editing of the wheat homolog of a susceptibility gene of O. sativa. Encodes wheat optimized Cas9 and gene specific sgRNA modules.

    Depositor

    Sophien Kamoun

    Insert

    Wheat_live_Cas9
    

    Use

    CRISPR

    Tags

    Expression

    Mutation

    Promoter

    Available since

    July 16, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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16. bU6-sgNeo1-mU6-sgNT-hU6-sgSnrk

    Plasmid

    #177236

    Purpose

    Expresses neomycin (bU6), non-targeting (mU6) and Snrk (hU6) gRNAs and Cre-recombinase

    Depositor

    Monte Winslow

    Insert

    sgNeo1/sgNT1/sgSnrk
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    bU6/mU6/hU6

    Available since

    Jan. 24, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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17. pHnS KI;Actb Donor;3xV5 KO;Dlg4

    Plasmid

    #240292

    Purpose

    KI:Actb Donor:3xV5 KO:Dlg4

    Depositor

    Yuki Ogawa

    Insert

    KI gRNA for Actb
    

    Use

    AAV

    Tags

    Expression

    Mutation

    NA

    Promoter

    Available since

    July 11, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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18. pUCsRNAP

    Plasmid

    #182746

    Purpose

    Swapping in small RNA promoter, 23-bp spacer sequence, & 19-bp repeats into pJC005 plasmids

    Depositor

    James Collins

    Article

    Chua et al Microbiol Spectr. 2022 Feb 2:e0242721. d

    Insert

    small RNA promoter, a 23-bp spacer sequence, & 19-bp repeats
    

    Use

    CRISPR

    Tags

    Expression

    Mutation

    Promoter

    Available since

    March 29, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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19. pHK352.3

    Plasmid

    #235473

    Purpose

    Message phagemid carrying sgRNA3 (prom. J23110, backbone RSF1030)

    Depositor

    Yolanda Schaerli

    Article

    et al Nat Commun 16, 3569 (2025)

    Insert

    sgRNA3
    

    Use

    Synthetic Biology

    Tags

    Expression

    Mutation

    Promoter

    Available since

    April 30, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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20. pcDNA-LUCI-GECO1

    Plasmid

    #113675

    Purpose

    Genetically-encoded ratiometric bioluminescent Ca2+ indicator based on GCaMP6s

    Depositor

    Robert Campbell

    Article

    Qian et al Chembiochem. 2018 Jun 22. doi: 10.1002/c

    Insert

    LUCI-GECO1
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    Aug. 10, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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