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gCBEv2

Plasmid

#220617

Purpose

vector for encoding an engineered glycosylase-based cytosine (C) base editor (gCBEv2) driven by EF1a promoter, guide RNAs compatible with SpCas9 driven by hU6, mCherry driven by CBh promoter

Depositor

Huawei Tong

Article

Tong et al Nat Commun. 2024 Jun 8;15(1):4897. doi:

Insert

hUNG2-nSpCas9

Expression

Mammalian

Mutation

hUNG2(del1-88;N213D,K184A,A214V), SpCas9(D10A)

Promoter

hU6, EF1a

Available Since

June 21, 2024

Availability

Academic Institutions and Nonprofits only

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pAAV-G88P3-HA-hM3Dq

Plasmid

#213972

Purpose

AAV vector with G88P3 promoter that can drive robust gene expression in MSNs

Depositor

Zhonghua Lu

Article

Chen et al Cell. 2023 Nov 22;186(24):5394-5410.e18.

Insert

hM3D (Gq)

Use

AAV

Promoter

G88P3

Available Since

May 15, 2024

Availability

Academic Institutions and Nonprofits only

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pcDNA 3.3 N-MYC RMDN3

Plasmid

#227878

Purpose

Used for transfection of cells for expression of C-MYC RMDN3

Depositor

Sheng-cai Lin

Article

Li et al Cell Res. 2024 Jun 19. doi: 10.1038/s414

Insert

RMDN3 (RMDN3 Human)

Tags

MYC

Expression

Mammalian

Available Since

July 8, 2025

Availability

Academic Institutions and Nonprofits only

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pcDNA 3.3 C-HA ZO1

Plasmid

#227883

Purpose

Used for transfection of cells for expression of N-HA ZO1

Depositor

Sheng-cai Lin

Article

Li et al Cell Res. 2024 Jun 19. doi: 10.1038/s414

Insert

ZO1 (TJP1 Human)

Tags

HA

Expression

Mammalian

Available Since

Oct. 15, 2025

Availability

Academic Institutions and Nonprofits only

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pcDNA 3.3 N-MYC TB182

Plasmid

#227882

Purpose

Used for transfection of cells for expression of C-MYC TB182

Depositor

Sheng-cai Lin

Article

Li et al Cell Res. 2024 Jun 19. doi: 10.1038/s414

Insert

TB182 (TNKS1BP1 Human)

Tags

MYC

Expression

Mammalian

Available Since

July 8, 2025

Availability

Academic Institutions and Nonprofits only

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pcDNA 3.3 N-MYC PDHA1

Plasmid

#227877

Purpose

Used for transfection of cells for expression of C-MYC PDHA1

Depositor

Sheng-cai Lin

Article

Li et al Cell Res. 2024 Jun 19. doi: 10.1038/s414

Insert

PDHA1 (PDHA1 Human)

Tags

MYC

Expression

Mammalian

Available Since

July 8, 2025

Availability

Academic Institutions and Nonprofits only

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pcDNA 3.3 C-MYC pdzd-8(536A)

Plasmid

#227885

Purpose

Used for transfection of cells for expression of C-MYC pdzd-8(536A)

Depositor

Sheng-cai Lin

Article

Li et al Cell Res. 2024 Jun 19. doi: 10.1038/s414

Insert

pdzd-8 (C53B4.4 Nematode)

Tags

MYC

Expression

Mammalian

Mutation

S536A

Available Since

July 8, 2025

Availability

Academic Institutions and Nonprofits only

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pcDNA 3.3 N-MYC pdzd-8

Plasmid

#227844

Purpose

Used for transfection of cells for expression of C-MYC pdzd-8

Depositor

Sheng-cai Lin

Article

Li et al Cell Res. 2024 Jun 19. doi: 10.1038/s414

Insert

pdzd-8 (C53B4.4 Nematode)

Tags

MYC

Expression

Mammalian

Available Since

June 27, 2025

Availability

Academic Institutions and Nonprofits only

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pH-ePPE

Plasmid

#183097

Purpose

For plant prime editing in rice plants

Depositor

Caixia Gao

Article

Zong et al Nat Biotechnol. 2022 Mar 24. doi: 10.103

Insert

Nls-nCas9-NC-nls-MLV-Nls

Use

CRISPR

Expression

Plant

Mutation

D10A in SpCas9

Available Since

April 6, 2022

Availability

Academic Institutions and Nonprofits only

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ePPE-spG

Plasmid

#183096

Purpose

For plant prime editing in rice plants or monocotyledons protoplasts

Depositor

Caixia Gao

Article

Zong et al Nat Biotechnol. 2022 Mar 24. doi: 10.103

Insert

Nls-nspGCas9-NC-nls-MLV-Nls

Use

CRISPR

Expression

Plant

Mutation

D10A in SpGCas9

Available Since

April 6, 2022

Availability

Academic Institutions and Nonprofits only

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ePPE

Plasmid

#183095

Purpose

For plant prime editing in rice plants or monocotyledons protoplasts

Depositor

Caixia Gao

Article

Zong et al Nat Biotechnol. 2022 Mar 24. doi: 10.103

Insert

Nls-nCas9-NC-nls-MLV-Nls

Use

CRISPR

Expression

Plant

Mutation

D10A in SpCas9

Available Since

April 6, 2022

Availability

Academic Institutions and Nonprofits only

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pCMX-Gal4-TEAD3

Plasmid

#33106

Depositor

Kunliang Guan

Article

Zhao et al Genes Dev. 2008 Jul 15. 22(14):1962-71.

Insert

TEAD3 (TEAD3 Human)

Tags

Gal4

Expression

Mammalian

Available Since

Feb. 10, 2012

Availability

Academic Institutions and Nonprofits only
pEGFP-C1-A20

Plasmid

#22141

Depositor

Yihong Ye

Article

Li et al Biochim Biophys Acta. 2008 Jun . 1783(6)

Insert

A20 (TNFAIP3 Human)

Tags

GFP

Expression

Mammalian

Available Since

Oct. 5, 2009

Availability

Academic Institutions and Nonprofits only

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p3xFLAG-zDrosha

Plasmid

#171540

Purpose

Encodes Zebrafish Drosha protein

Depositor

Yan Zeng

Article

Li et al Biochem Biophys Res Commun. 2019 Jun 18;

Insert

drosha (rnasen Zebrafish)

Expression

Mammalian

Available Since

July 20, 2021

Availability

Academic Institutions and Nonprofits only

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pNA0306

Plasmid

#169452

Purpose

pRS415-TEF1p-Cas9-CYC1t; Cas9 expression plasmid

Depositor

Jef Boeke

Article

Xie et al G3 (Bethesda). 2018 Jan 4;8(1):173-183.

Insert

Cas9

Expression

Yeast

Promoter

TEF1p

Available Since

July 6, 2021

Availability

Academic Institutions and Nonprofits only

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pCMV-Flag-YAP-S94A

Plasmid

#33102

Depositor

Kunliang Guan

Article

Zhao et al Genes Dev. 2008 Jul 15. 22(14):1962-71.

Insert

YAP (YAP1 )

Tags

Flag

Expression

Mammalian

Mutation

S94A

Available Since

March 21, 2012

Availability

Academic Institutions and Nonprofits only

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pCMX-Gal4-TEAD2

Plasmid

#33107

Depositor

Kunliang Guan

Article

Zhao et al Genes Dev. 2008 Jul 15. 22(14):1962-71.

Insert

TEAD2 (TEAD2 Human)

Tags

Gal4

Expression

Mammalian

Available Since

Feb. 10, 2012

Availability

Academic Institutions and Nonprofits only

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pXZX352

Plasmid

#169456

Purpose

MATA fragment in pTOPO vector

Depositor

Jef Boeke

Article

Xie et al G3 (Bethesda). 2018 Jan 4;8(1):173-183.

Insert

Mata locus

Expression

Bacterial

Promoter

lac

Available Since

July 21, 2021

Availability

Academic Institutions and Nonprofits only

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pXZX353

Plasmid

#169457

Purpose

MATα (alpha) fragment in pTOPO vector

Depositor

Jef Boeke

Article

Xie et al G3 (Bethesda). 2018 Jan 4;8(1):173-183.

Insert

MatA

Expression

Bacterial

Promoter

lac

Available Since

June 10, 2021

Availability

Academic Institutions and Nonprofits only

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p23-NLS-RfxCas13d-mcherry-NLS-Flag

Plasmid

#165077

Purpose

overexpression of RfxCas13d in human cells

Depositor

Ling-Ling Chen

Article

Li et al Nat Methods. 2021 Jan;18(1):51-59. doi:

Insert

RfxCas13d

Expression

Mammalian

Available Since

May 7, 2021

Availability

Academic Institutions and Nonprofits only

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