We narrowed to 82 results for: LIS

1. Lenti-human-TF-gRNA-puromycin

   Pooled Library

   #162275

   Purpose

   Knockout library targeting a set of human transcription factors for loss-of-function screening.

   Depositor

   Chunliang Li

   Article

   Zhang et al Elife. 2020 Oct 1;9. pii: 57858. doi: 10

   Species

   Homo sapiens

   Use

   Lentiviral

   Available Since

   Dec. 15, 2020

   Availability

   Academic Institutions and Nonprofits only

2. Lenti-human-UBDUB-gRNA-puromycin-IRES-CFP

   Pooled Library

   #171531

   Purpose

   Knockout library targeting ubiquitination and de-ubiquitination complex genes.

   Depositor

   Chunliang Li

   Article

   Wright et al Proc Natl Acad Sci U S A. 2023 Apr 18;12

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   Lentiviral

   Available Since

   June 22, 2021

   Availability

   Academic Institutions and Nonprofits only

3. Mouse Metabolism Library

   Pooled Library

   #163966

   Purpose

   Knockout library targeting mouse metabolic genes.

   Depositor

   Alec Kimmelman

   Article

   Biancur et al Cell Metab. 2020 Oct 28. pii: S1550-4131

   Use

   CRISPR and Lentiviral

   Available Since

   July 1, 2021

   Availability

   Academic Institutions and Nonprofits only

4. Mouse metabolism knockout library

   Pooled Library

   #160129

   Purpose

   Targets mouse metabolic genes and includes most metabolic enzymes and transporters.

   Depositor

   Kivanc Birsoy

   Article

   Zhu et al Cell Metab. 2020 Oct 28. pii: S1550-4131

   Expression

   Mammalian

   Species

   Mus musculus

   Use

   CRISPR and Lentiviral

   Available Since

   Nov. 10, 2020

   Availability

   Academic Institutions and Nonprofits only

5. Mouse lipid metabolism knockout library

   Pooled Library

   #206248

   Purpose

   The lipid metabolism library contains guide RNAs against 295 genes targeting mouse genes encoding enzymes that directly impact lipid metabolism.

   Depositor

   Kivanc Birsoy

   Article

   Soula et al Nature. 2024 Aug 7. doi: 10.1038/s41586-

   Use

   CRISPR and Lentiviral

   Available Since

   Aug. 29, 2024

   Availability

   Academic Institutions and Nonprofits only

6. Human Lipid Droplet and Metabolism Library

   Pooled Library

   #191535

   Purpose

   Targets 1,196 genes related to lipid droplet biology and cell metabolism.

   Depositor

   James Olzmann

   Article

   Roberts et al Dev Cell. 2023 Jul 18:S1534-5807(23)0033

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available Since

   March 1, 2023

   Availability

   Academic Institutions and Nonprofits only

7. Mouse sphingolipid metabolism knockout library

   Pooled Library

   #206249

   Purpose

   The sphingolipid metabolism library targets 82 mouse genes in the de novo ceramide and downstream sphingolipid metabolism pathways.

   Depositor

   Kivanc Birsoy

   Article

   Soula et al Nature. 2024 Aug 7. doi: 10.1038/s41586-

   Use

   CRISPR and Lentiviral

   Available Since

   Aug. 29, 2024

   Availability

   Academic Institutions and Nonprofits only

8. Liu Lab MusCK Library A

   Pooled Library

   #174196

   Purpose

   MusCK library contains 23,622 unique sgRNAs targeting 4,787 gene locations in the genome. Sub-library MusCK A contains 5 gRNAs per gene.

   Depositor

   Xiaole Shirley Liu

   Article

   Wang et al Cell. 2021 Oct 14;184(21):5357-5374.e22.

   Expression

   Mammalian

   Species

   Mus musculus

   Use

   CRISPR and Lentiviral

   Available Since

   Oct. 29, 2021

   Availability

   Academic Institutions and Nonprofits only

9. Liu Lab MusCK Library B

   Pooled Library

   #174197

   Purpose

   MusCK library contains 23,622 unique sgRNAs targeting 4,787 gene locations in the genome. Sub-library MusCK M_b contains 5 gRNAs per gene.

   Depositor

   Xiaole Shirley Liu

   Article

   Wang et al Cell. 2021 Oct 14;184(21):5357-5374.e22.

   Expression

   Mammalian

   Species

   Mus musculus

   Use

   CRISPR and Lentiviral

   Available Since

   Oct. 29, 2021

   Availability

   Academic Institutions and Nonprofits only

10. pUC57kan-T7-mt-gRNA library

    Pooled Library

    #82480

    Purpose

    This library is intended to be used as a technical tool for removal of mitochondrial DNA from mouse genomic DNA preparations.

    Depositor

    Wei Xie

    Article

    Wu et al Nature. 2016 Jun 30;534(7609):652-7.

    Available Since

    April 5, 2017

    Availability

    Academic Institutions and Nonprofits only

11. Human genome-wide lentiviral CRISPR gRNA library version 1

    Pooled Library

    #67989

    Purpose

    Knockout library targeting 18,010 human genes. gRNAs were improved using a new design pipeline and improved gRNA scaffold.

    Depositor

    Kosuke Yusa

    Article

    Tzelepis et al Cell Rep. 2016 Oct 18;17(4):1193-1205. d

    Species

    Homo sapiens, Mus musculus, and Synthetic

    Use

    CRISPR and Lentiviral

    Available Since

    Oct. 14, 2016

    Availability

    Academic Institutions and Nonprofits only

12. Mouse genome-wide lentiviral CRISPR gRNA library version 2

    Pooled Library

    #67988

    Purpose

    Knockout library targeting 18,424 mouse genes. gRNAs were improved using a new design pipeline and improved gRNA scaffold.

    Depositor

    Kosuke Yusa

    Article

    Tzelepis et al Cell Rep. 2016 Oct 18;17(4):1193-1205. d

    Species

    Homo sapiens, Mus musculus, and Synthetic

    Use

    CRISPR and Lentiviral

    Available Since

    Oct. 14, 2016

    Availability

    Academic Institutions and Nonprofits only

13. Drosophila_sgRNA_group_2

    Pooled Library

    #134583

    Purpose

    Targets Drosophila orthologs of vertebrate genes that have undergone expansion in the vertebrate line

    Depositor

    Norbert Perrimon

    Article

    Viswanatha et al Elife. 2018 Jul 27;7. pii: 36333. doi: 1

    Expression

    Insect

    Species

    Drosophila melanogaster

    Use

    CRISPR

    Available Since

    Feb. 25, 2020

    Availability

    Academic Institutions and Nonprofits only

14. Drosophila_sgRNA_group_1

    Pooled Library

    #134582

    Purpose

    Targets kinases, phosphatases, and Drosophila orthologs of drug targets

    Depositor

    Norbert Perrimon

    Article

    Viswanatha et al Elife. 2018 Jul 27;7. pii: 36333. doi: 1

    Expression

    Insect

    Species

    Drosophila melanogaster

    Use

    CRISPR

    Available Since

    Feb. 25, 2020

    Availability

    Academic Institutions and Nonprofits only

15. Drosophila_sgRNA_group_3

    Pooled Library

    #134584

    Purpose

    Targets all other Drosophila genes not included in Groups 1 and 2

    Depositor

    Norbert Perrimon

    Article

    Viswanatha et al Elife. 2018 Jul 27;7. pii: 36333. doi: 1

    Expression

    Insect

    Species

    Drosophila melanogaster

    Use

    CRISPR

    Available Since

    Feb. 25, 2020

    Availability

    Academic Institutions and Nonprofits only

16. pre-associated oBC-mBC backbone (p025)

    Pooled Library

    #194097

    Purpose

    pre-associated oBC-mBC backbone (p025), can insert additional reporter constructs

    Depositor

    Jay Shendure

    Article

    Lalanne et al bioRxiv 2022.12.10.519236

    Expression

    Bacterial and Mammalian

    Use

    RNAi

    Available Since

    April 3, 2024

    Availability

    Academic Institutions and Nonprofits only

17. scQers promoter control #2 (low: no promoter, p029)

    Pooled Library

    #217421

    Purpose

    scQers promoter control #2 (low: no promoter, p029)

    Depositor

    Jay Shendure

    Article

    Lalanne et al bioRxiv 2022.12.10.519236

    Expression

    Bacterial and Mammalian

    Use

    RNAi

    Available Since

    April 3, 2024

    Availability

    Academic Institutions and Nonprofits only

18. pre-associated oBC-minP-GFP-mBC backbone (p043)

    Pooled Library

    #194098

    Purpose

    pre-associated oBC-minP-GFP-mBC backbone (p043), can directly be used to deposit library of regulatory elements

    Depositor

    Jay Shendure

    Article

    Lalanne et al bioRxiv 2022.12.10.519236

    Expression

    Bacterial and Mammalian

    Use

    RNAi

    Available Since

    April 3, 2024

    Availability

    Academic Institutions and Nonprofits only

19. scQers promoter control #1 (low: minimal promoter, p027)

    Pooled Library

    #217420

    Purpose

    scQers promoter control #1 (low: minimal promoter, p027)

    Depositor

    Jay Shendure

    Article

    Lalanne et al bioRxiv 2022.12.10.519236

    Expression

    Bacterial and Mammalian

    Use

    RNAi

    Available Since

    April 3, 2024

    Availability

    Academic Institutions and Nonprofits only

20. scQers promoter control #5 (high: EEF1A1 promoter, p028)

    Pooled Library

    #217424

    Purpose

    scQers promoter control #5 (high: EEF1A1 promoter, p028)

    Depositor

    Jay Shendure

    Article

    Lalanne et al bioRxiv 2022.12.10.519236

    Expression

    Bacterial and Mammalian

    Use

    RNAi

    Available Since

    April 3, 2024

    Availability

    Academic Institutions and Nonprofits only