We narrowed to 9,550 results for: APP

Showing: 8261 - 8280 of 9550 results

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pUAS-hhN-HA

Plasmid

#240236

Purpose

Expression of hhN-HA under control of UAS promoter. Can be used to generate transgenic fly lines by white+ fly eye selection and phiC31 integration.

Depositor

Justin Bosch, Norbert Perrimon

Article

Bosch et al Nat Commun. 2026 Apr 20. doi: 10.1038/s4

Insert

hedgehog N-terminal fragment (hh Fly)

Tags

HA-spGFP11

Expression

Insect

Mutation

aa 1-257

Promoter

UAS

Available Since

July 11, 2025

Availability

Academic Institutions and Nonprofits only

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pcDNA3.1-GSDMD_Q29A

Plasmid

#224702

Purpose

Expression of mutated Gasdermin D_Q29A (GSDMD_Q29A) in transfected mammalian cell lines

Depositor

Christopher Overall

Article

Grin et al Cell Rep. 2024 Dec 24;43(12):115080. doi

Insert

GSDMD_Q29A (GSDMD Human)

Tags

FLAG

Expression

Mammalian

Mutation

Q29A

Promoter

CMV

Available Since

July 2, 2025

Availability

Industry, Academic Institutions, and Nonprofits

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pcDNA3.1-GSDMD_Q29A_H270A

Plasmid

#224703

Purpose

Expression of mutant Gasdermin D_Q29A_H270A (GSDMD_Q29A_H270A) in transfected mammalian cell lines

Depositor

Christopher Overall

Article

Grin et al Cell Rep. 2024 Dec 24;43(12):115080. doi

Insert

GSDMD_Q29A_H270A (GSDMD Human)

Tags

FLAG

Expression

Mammalian

Mutation

Q29A and H270A

Promoter

CMV

Available Since

July 2, 2025

Availability

Industry, Academic Institutions, and Nonprofits

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pcDNA3.1-GSDMD_D275A

Plasmid

#224704

Purpose

Expression of mutated Gasdermin D_D275A (GSDMD_D275A) in transfected mammalian cell lines

Depositor

Christopher Overall

Article

Grin et al Cell Rep. 2024 Dec 24;43(12):115080. doi

Insert

GSDMD_D275A (GSDMD Human)

Tags

FLAG

Expression

Mammalian

Mutation

D275A

Promoter

CVM

Available Since

July 2, 2025

Availability

Industry, Academic Institutions, and Nonprofits

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pcDNA3.1-GSDMD_H270A_D275A

Plasmid

#224705

Purpose

Expression of mutated Gasdermin D_H270A_D275A (GSDMD_D275A) in transfected mammalian cell lines

Depositor

Christopher Overall

Article

Grin et al Cell Rep. 2024 Dec 24;43(12):115080. doi

Insert

GSDMD_Q29A_H270A (GSDMD Human)

Tags

FLAG

Expression

Mammalian

Mutation

H270A and D275A

Promoter

CMV

Available Since

July 2, 2025

Availability

Industry, Academic Institutions, and Nonprofits

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pcDNA3.1-GSDMD_H270A

Plasmid

#224701

Purpose

Expression of mutated Gasdermin D_H270A (GSDMD_H270A) in transfected mammalian cell lines

Depositor

Christopher Overall

Article

Grin et al Cell Rep. 2024 Dec 24;43(12):115080. doi

Insert

GSDMD_H270A (GSDMD Human)

Tags

FLAG

Expression

Mammalian

Mutation

H270A

Promoter

CMV

Available Since

July 2, 2025

Availability

Industry, Academic Institutions, and Nonprofits

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pKLV2-U6gRNA5(hBIRC2_1k)-PGKpuro2ABFP-W

Plasmid

#208416

Purpose

Lentiviral gRNA plasmid targeting human BIRC2 gene, co-expression of BFP tag

Depositor

Sok Ching Cheong

Article

Chai et al Cancer Res Commun. 2024 Nov 1;4(11):2919

Insert

BIRC2 (BIRC2 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Mutation

N/A

Promoter

human U6

Available Since

July 1, 2025

Availability

Academic Institutions and Nonprofits only

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pKLV2-U6gRNA5(hBIRC2_2b)-PGKpuro2ABFP-W

Plasmid

#208417

Purpose

Lentiviral gRNA plasmid targeting human BIRC2 gene, co-expression of BFP tag

Depositor

Sok Ching Cheong

Article

Chai et al Cancer Res Commun. 2024 Nov 1;4(11):2919

Insert

BIRC2 (BIRC2 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Mutation

N/A

Promoter

human U6

Available Since

July 1, 2025

Availability

Academic Institutions and Nonprofits only

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pKLV2-U6gRNA5(hIKBKG_1k)-PGKpuro2ABFP-W

Plasmid

#208410

Purpose

Lentiviral gRNA plasmid targeting human IKBKG gene, co-expression of BFP tag

Depositor

Sok Ching Cheong

Article

Chai et al Cancer Res Commun. 2024 Nov 1;4(11):2919

Insert

IKBKG (IKBKG Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Mutation

N/A

Promoter

human U6

Available Since

July 1, 2025

Availability

Academic Institutions and Nonprofits only

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pKLV2-U6gRNA5(hIKBKG_2m)-PGKpuro2ABFP-W

Plasmid

#208411

Purpose

Lentiviral gRNA plasmid targeting human IKBKG gene, co-expression of BFP tag

Depositor

Sok Ching Cheong

Article

Chai et al Cancer Res Commun. 2024 Nov 1;4(11):2919

Insert

IKBKG (IKBKG Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Mutation

N/A

Promoter

human U6

Available Since

July 1, 2025

Availability

Academic Institutions and Nonprofits only

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pKLV2-U6gRNA5(hMAP3K7_1k)-PGKpuro2ABFP-W

Plasmid

#208412

Purpose

Lentiviral gRNA plasmid targeting human MAP3K7 gene, co-expression of BFP tag

Depositor

Sok Ching Cheong

Article

Chai et al Cancer Res Commun. 2024 Nov 1;4(11):2919

Insert

MAP3K7 (MAP3K7 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Mutation

N/A

Promoter

human U6

Available Since

July 1, 2025

Availability

Academic Institutions and Nonprofits only

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pKLV2-U6gRNA5(hMAP3K7_2m)-PGKpuro2ABFP-W

Plasmid

#208413

Purpose

Lentiviral gRNA plasmid targeting human MAP3K7 gene, co-expression of BFP tag

Depositor

Sok Ching Cheong

Article

Chai et al Cancer Res Commun. 2024 Nov 1;4(11):2919

Insert

MAP3K7 (MAP3K7 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Mutation

N/A

Promoter

human U6

Available Since

July 1, 2025

Availability

Academic Institutions and Nonprofits only

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TRAV38-2/DV8

Plasmid

#237992

Purpose

Encodes TRAV38-2/DV8 allele, P2A, and TRBC to generate TCRs via cloning

Depositor

Michael Birnbaum

Article

Gaglione et al Immunity. 2026 Feb 10;59(2):477-493.e9.

Insert

TRBC-P2A-TRAV38-2/DV8 (TRAV38-2DV8 Human)

Use

Synthetic Biology

Mutation

None

Available Since

June 12, 2025

Availability

Academic Institutions and Nonprofits only

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TRAV36/DV7

Plasmid

#237990

Purpose

Encodes TRAV36/DV7 allele, P2A, and TRBC to generate TCRs via cloning

Depositor

Michael Birnbaum

Article

Gaglione et al Immunity. 2026 Feb 10;59(2):477-493.e9.

Insert

TRBC-P2A-TRAV36/DV7 (TRAV36DV7 Human)

Use

Synthetic Biology

Mutation

None

Available Since

June 12, 2025

Availability

Academic Institutions and Nonprofits only

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TRAV23/DV6

Plasmid

#237980

Purpose

Encodes TRAV23/DV6 allele, P2A, and TRBC to generate TCRs via cloning

Depositor

Michael Birnbaum

Article

Gaglione et al Immunity. 2026 Feb 10;59(2):477-493.e9.

Insert

TRBC-P2A-TRAV23/DV6 (TRAV23DV6 Human)

Use

Synthetic Biology

Mutation

None

Available Since

June 12, 2025

Availability

Academic Institutions and Nonprofits only

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TRAV18

Plasmid

#237975

Purpose

Encodes TRAV18 allele, P2A, and TRBC to generate TCRs via cloning

Depositor

Michael Birnbaum

Article

Gaglione et al Immunity. 2026 Feb 10;59(2):477-493.e9.

Insert

TRBC-P2A-TRAV18 (TRAV18, TRBC1 Human)

Use

Synthetic Biology

Mutation

None

Available Since

June 12, 2025

Availability

Academic Institutions and Nonprofits only

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pRCA378 - pBA904 Puro-T2A-GFP CD45 CRISPRa guide 3 (pRCA360 backbone)

Plasmid

#238169

Purpose

Lentiviral CRISPR guide vector expressing PTPRC targeting sgRNA with cs1 incorporated in the loop of the sgRNA constant region for 10X Direct Capture

Depositor

Thomas Norman

Article

Southard et al Nat Genet. 2025 Aug 6. doi: 10.1038/s415

Insert

CD45 sgRNA CRISPRa (PTPRC Human, Synthetic)

Use

CRISPR and Lentiviral

Tags

GFP

Available Since

June 3, 2025

Availability

Academic Institutions and Nonprofits only

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pMCB320 sgCdkn1a.1

Plasmid

#227945

Purpose

sgRNA targeting Cdkn1a, mCherry, puromycin resistance, Mammalian expression, Mouse targeting, lentiviral, CRISPR

Depositor

Laura Attardi

Article

Boutelle et al Cell Death Differ. 2025 Apr 22. doi: 10.

Insert

Cdkn1a.1 (Cdkn1a Mouse)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

mouse U6

Available Since

April 24, 2025

Availability

Academic Institutions and Nonprofits only

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pMCB320 sgCdkn1a.2

Plasmid

#227946

Purpose

sgRNA targeting Cdkn1a, mCherry, puromycin resistance, Mammalian expression, Mouse targeting, lentiviral, CRISPR

Depositor

Laura Attardi

Article

Boutelle et al Cell Death Differ. 2025 Apr 22. doi: 10.

Insert

Cdkn1a.2 (Cdkn1a Mouse)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

mouse U6

Available Since

April 24, 2025

Availability

Academic Institutions and Nonprofits only

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TH1150-pOCC177-FUS(Nhe)-PLD_YtoF_RGG_RtoK

Plasmid

#221889

Purpose

Shuttle vector for baculovirus production, using FlashBac bacmid

Depositor

Anthony Hyman

Article

Wang et al Cell. 2018 Jul 26;174(3):688-699.e16. do

Insert

FUS (FUS Human)

Tags

6xHis-MBP-PreScission and TEV-SNAP-tag

Expression

Insect

Mutation

In PLD all Tyr (Y) changed to Phe (F), in RGG (aa…

Promoter

PH promoter

Available Since

March 26, 2025

Availability

Academic Institutions and Nonprofits only

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