We narrowed to 9,959 results for: CAG

Showing: 9281 - 9300 of 9959 results

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MAP3K2 gRNA (BRDN0001145545)

Plasmid

#75509

Purpose

3rd generation lentiviral gRNA plasmid targeting human MAP3K2

Depositor

John Doench, David Root

Publication

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

MAP3K2 (MAP3K2 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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TEX14 gRNA (BRDN0001146944)

Plasmid

#76831

Purpose

3rd generation lentiviral gRNA plasmid targeting human TEX14

Depositor

John Doench, David Root

Publication

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

TEX14 (TEX14 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available since

June 28, 2016

Availability

Academic Institutions and Nonprofits only

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OXSR1 gRNA (BRDN0001148375)

Plasmid

#77750

Purpose

3rd generation lentiviral gRNA plasmid targeting human OXSR1

Depositor

John Doench, David Root

Publication

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

OXSR1 (OXSR1 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available since

June 24, 2016

Availability

Academic Institutions and Nonprofits only

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pMIR-192-Reporter

Plasmid

#71872

Purpose

Mammalian expression vector for the analysis of miR-19α activity

Depositor

Mien-Chie Hung

Publication

Shen et al Nature. 2013 May 16;497(7449):383-7. doi

Insert

Reverse complementary sequence of miR-192

Tags

firefly luciferase

Expression

Mammalian

Promoter

CMV

Available since

May 4, 2016

Availability

Academic Institutions and Nonprofits only
pRDB-054_4x_crAAVS1

Plasmid

#261344

Purpose

Lentiviral vector encoding enAsCas12a and a four-guide casette targeting the human AAVS1 safe-harbor locus under puro selection

Depositor

Samuel McBrayer

Publication

Abdullah et al Cell. 2026 Sep 15:S0092-8674(26)01010-X.

Insert

AAVS1 (AAVS1 Human)

Use

CRISPR and Lentiviral

Tags

Nucleoplasmin NLS, 3xHA

Expression

Mammalian

Promoter

EF-1alpha

Available since

Sept. 15, 2026

Availability

Academic Institutions and Nonprofits only

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pKLV2-U6gRNA5(sgCXCR1-2)-PGKpuro2ABFP-W

Plasmid

#252916

Purpose

Expression vector for gRNA with Puro and tagBFP selection markers

Depositor

Sok Ching Cheong

Insert

CXCR1 (CXCR1 Human)

Use

CRISPR

Promoter

human U6 promoter, mouse PGK promoter

Available since

April 2, 2026

Availability

Academic Institutions and Nonprofits only

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pKLV2-U6gRNA5(sgCXCR1-1)-PGKpuro2ABFP-W

Plasmid

#252915

Purpose

Expression vector for gRNA with Puro and tagBFP selection markers

Depositor

Sok Ching Cheong

Insert

CXCR1 (CXCR1 Human)

Use

CRISPR

Promoter

human U6 promoter, mouse PGK promoter

Available since

April 2, 2026

Availability

Academic Institutions and Nonprofits only

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rDNA-adj gRNA #3

Plasmid

#247549

Purpose

negative control for Crispri KD

Depositor

Miguel Ramalho-Santos

Publication

Ataei et al Genes Dev. 2025 Feb 3;39(3-4):280-298. d

Insert

negative control sgRNA targeting region adjacent to 5' end of ribosomal DNA repeats of distal junction

Use

CRISPR

Expression

Mammalian

Mutation

none

Available since

March 16, 2026

Availability

Academic Institutions and Nonprofits only

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pLenti-hITGA3-gRNA1

Plasmid

#249219

Purpose

ITGA3 CRISPR KO

Depositor

Weihong Tan

Publication

Luo et al Science. 2026 Jan;391(6780):eadv6127. do

Insert

ITGA3 (ITGA3 Human)

Use

CRISPR and Lentiviral

Promoter

U6

Available since

Feb. 11, 2026

Availability

Academic Institutions and Nonprofits only

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LentiCRISPR-B_sgRNA_EXOSC7 (pP18(T)_C4-AVA4066)

Plasmid

#239305

Purpose

Lentiviral vector expressing Cas9-P2A-Blasticidin and an sgRNA targeting EXOSC7

Depositor

Andrei Alexandrov

Publication

Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

Insert

U6-driven sgRNA targeting EXOSC7 (EXOSC7 Human)

Use

CRISPR and Lentiviral

Available since

Aug. 4, 2025

Availability

Academic Institutions and Nonprofits only

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LentiCRISPR-B_sgRNA_EXOSC2 (pP18(T)_C3-AVA4067)

Plasmid

#239301

Purpose

Lentiviral vector expressing Cas9-P2A-Blasticidin and an sgRNA targeting EXOSC2

Depositor

Andrei Alexandrov

Publication

Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

Insert

U6-driven sgRNA targeting EXOSC2 (EXOSC2 Human)

Use

CRISPR and Lentiviral

Available since

Aug. 4, 2025

Availability

Academic Institutions and Nonprofits only

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pRCA376 - pBA904 Puro-T2A-GFP NTC guide (pRCA360 backbone)

Plasmid

#238167

Purpose

Lentiviral CRISPR guide vector expressing a non-targeting sgRNA with cs1 incorporated in the loop of the sgRNA constant region for 10X Direct Capture

Depositor

Thomas Norman

Publication

Southard et al Nat Genet. 2025 Aug 6. doi: 10.1038/s415

Insert

Non-targeting sgRNA

Use

CRISPR and Lentiviral

Tags

GFP

Available since

June 3, 2025

Availability

Academic Institutions and Nonprofits only

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pMCB320 sgCdkn1a.1

Plasmid

#227945

Purpose

sgRNA targeting Cdkn1a, mCherry, puromycin resistance, Mammalian expression, Mouse targeting, lentiviral, CRISPR

Depositor

Laura Attardi

Publication

Boutelle et al Cell Death Differ. 2025 Apr 22. doi: 10.

Insert

Cdkn1a.1 (Cdkn1a Mouse)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

mouse U6

Available since

April 24, 2025

Availability

Academic Institutions and Nonprofits only

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pcDNA3.1-hSyncytin-1(AAAR)

Plasmid

#182442

Purpose

hSyncytin-1, furin cleavage site RNKR>AAAR(314-317)

Depositor

Masaharu Somiya

Insert

ERVW-1 (ERVW-1 Human)

Expression

Mammalian

Mutation

furin cleacage site RNKR>>AAAR(314-317)

Promoter

CMV

Available since

April 1, 2025

Availability

Academic Institutions and Nonprofits only

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sgMST1/2-1

Plasmid

#229429

Purpose

knockout of MST1 and MST2

Depositor

Christopher Vakoc

Publication

Klingbeil et al Cancer Discov. 2024 Jul 26. doi: 10.1158

Insert

sgMST1/2-1 (MST1, STK3 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6;bU6;EFS

Available since

Dec. 18, 2024

Availability

Academic Institutions and Nonprofits only

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pUC19-U6-SpCas9_gRNA-OPA1-del_exon5-gRNA2a_(CJT91)

Plasmid

#226991

Purpose

pUC19 plasmid with U6 promoter and SpCas9 gRNA to create an OPA1-del_exon5 cell line via nuclease mediate excision, gRNA 2a must be used with gRNA 1a or 1b

Depositor

Benjamin Kleinstiver

Publication

Fry et al EMBO J. 2024 Feb;43(3):391-413. doi: 10.

Insert

SpCas9 gRNA 2a to create OPA1-del_exon5

Use

CRISPR

Expression

Mammalian

Promoter

U6

Available since

Nov. 21, 2024

Availability

Academic Institutions and Nonprofits only

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pUC19-U6-SpCas9_gRNA-OPA1-createR194G-A6-gRNA_(CJT88)

Plasmid

#226987

Purpose

pUC19 plasmid with U6 promoter and SpCas9 gRNA to create an OPA1-R194G cell line via adenine base editing (target base in position A6)

Depositor

Benjamin Kleinstiver

Publication

Fry et al EMBO J. 2024 Feb;43(3):391-413. doi: 10.

Insert

SpCas9 gRNA A6 to create OPA1-R194G

Use

CRISPR

Expression

Mammalian

Promoter

U6

Available since

Nov. 6, 2024

Availability

Academic Institutions and Nonprofits only

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pUC19-U6-SpCas9_gRNA-OPA1-createR194G-A7-gRNA_(CJT89)

Plasmid

#226986

Purpose

pUC19 plasmid with U6 promoter and SpCas9 gRNA to create an OPA1-R194G cell line via adenine base editing (target base in position A7)

Depositor

Benjamin Kleinstiver

Publication

Fry et al EMBO J. 2024 Feb;43(3):391-413. doi: 10.

Insert

SpCas9 gRNA A7 to create OPA1-R194G

Use

CRISPR

Expression

Mammalian

Promoter

U6

Available since

Nov. 6, 2024

Availability

Academic Institutions and Nonprofits only

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pUC19-U6-SpCas9_gRNA-OPA1-del_exon5-gRNA2b_(CJT93)

Plasmid

#226992

Purpose

pUC19 plasmid with U6 promoter and SpCas9 gRNA to create an OPA1-del_exon5 cell line via nuclease mediate excision, gRNA 2b must be used with gRNA 1a or 1b

Depositor

Benjamin Kleinstiver

Publication

Fry et al EMBO J. 2024 Feb;43(3):391-413. doi: 10.

Insert

SpCas9 gRNA 2b to create OPA1-del_exon5

Use

CRISPR

Expression

Mammalian

Promoter

U6

Available since

Nov. 5, 2024

Availability

Academic Institutions and Nonprofits only

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pUC19-U6-SpCas9_gRNA-OPA1-createR194G-A9-gRNA_(CJT87)

Plasmid

#226988

Purpose

pUC19 plasmid with U6 promoter and SpCas9 gRNA to create an OPA1-R194G cell line via adenine base editing (target base in position A9)

Depositor

Benjamin Kleinstiver

Publication

Fry et al EMBO J. 2024 Feb;43(3):391-413. doi: 10.

Insert

SpCas9 gRNA A9 to create OPA1-R194G

Use

CRISPR

Expression

Mammalian

Promoter

U6

Available since

Nov. 5, 2024

Availability

Academic Institutions and Nonprofits only

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