We narrowed to 88,932 results for: Mal;

1. pWZL-hygro-FAKS722A

   Plasmid

   #216545

   Purpose

   This retroviral plasmid expresses a mutated cDNA (dominant negative: S722A) of human PTK2

   Depositor

   Georgia Konstantinidou

   Article

   Pozzato et al EMBO Mol Med. 2024 Sep 13. doi: 10.1038/

   Insert

   PTK2 (S722A) (PTK2 Human)
   

   Use

   Retroviral

   Tags

   No

   Expression

   Mammalian

   Mutation

   FAK dominant negative mutation S722A

   Available Since

   Sept. 16, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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2. pWZL-hygro-FAKY861F

   Plasmid

   #216546

   Purpose

   This retroviral plasmid expresses a mutated cDNA (dominant negative: Y861F) of human PTK2

   Depositor

   Georgia Konstantinidou

   Article

   Pozzato et al EMBO Mol Med. 2024 Sep 13. doi: 10.1038/

   Insert

   PTK2 (Y861F) (PTK2 Human)
   

   Use

   Retroviral

   Tags

   No

   Expression

   Mammalian

   Mutation

   FAK dominant negative mutation Y861F

   Available Since

   Sept. 16, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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3. pWZL-hygro-FAKY397F

   Plasmid

   #216677

   Purpose

   This retroviral plasmid expresses a mutated cDNA (dominant negative: Y397F) of human PTK2

   Depositor

   Georgia Konstantinidou

   Article

   Pozzato et al EMBO Mol Med. 2024 Sep 13. doi: 10.1038/

   Insert

   PTK2 (Y397F) (PTK2 Human)
   

   Use

   Retroviral

   Tags

   No

   Expression

   Mammalian

   Mutation

   FAK dominant negative mutation Y397F

   Available Since

   Sept. 16, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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4. pWZL-hygro-FAKS732A

   Plasmid

   #216541

   Purpose

   This retroviral plasmid expresses a mutated cDNA (dominant negative: S732A) of human PTK2

   Depositor

   Georgia Konstantinidou

   Article

   Pozzato et al EMBO Mol Med. 2024 Sep 13. doi: 10.1038/

   Insert

   PTK2 (S732A) (PTK2 Human)
   

   Use

   Retroviral

   Tags

   No

   Expression

   Mammalian

   Mutation

   FAK dominant negative mutation S732A

   Available Since

   Sept. 16, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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5. pWZL-hygro-FAKS910A

   Plasmid

   #216542

   Purpose

   This retroviral plasmid expresses a mutated cDNA (dominant negative: S910A) of human PTK2

   Depositor

   Georgia Konstantinidou

   Article

   Pozzato et al EMBO Mol Med. 2024 Sep 13. doi: 10.1038/

   Insert

   PTK2 (S910A) (PTK2 Human)
   

   Use

   Retroviral

   Tags

   No

   Expression

   Mammalian

   Mutation

   FAK dominant negative mutation S910A

   Available Since

   Sept. 16, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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6. pET21b-Cdc42/13C-FKBP-MBP

   Plasmid

   #214291

   Purpose

   Express split-Cdc42 fragment fused with FKBP and MBP

   Depositor

   Cliff Stains

   Article

   He et al Angew Chem Int Ed Engl. 2024 Jul 26:e202

   Insert

   Split-Cdc42 fragment fused with FKBP (CDC42 Human)
   

   Tags

   Maltose-binding protein (MBP)

   Expression

   Bacterial

   Mutation

   Cdc42-Q61L

   Promoter

   T7

   Available Since

   July 29, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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7. pET21b-Rac1/13C-FKBP-MBP

   Plasmid

   #214295

   Purpose

   Express split-Rac1 fragment fused with FKBP and MBP

   Depositor

   Cliff Stains

   Article

   He et al Angew Chem Int Ed Engl. 2024 Jul 26:e202

   Insert

   Split-Rac1 fragment fused with FKBP (RAC1 Human)
   

   Tags

   Maltose-binding protein (MBP)

   Expression

   Bacterial

   Mutation

   Rac1-Q61L

   Promoter

   T7

   Available Since

   July 29, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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8. pET21b-RhoA/13C-FKBP-MBP

   Plasmid

   #214299

   Purpose

   Express split-RhoA fragment fused with FKBP and MBP

   Depositor

   Cliff Stains

   Article

   He et al Angew Chem Int Ed Engl. 2024 Jul 26:e202

   Insert

   Split-RhoA fragment fused with FKBP (RHOA Human)
   

   Tags

   Maltose-binding protein (MBP)

   Expression

   Bacterial

   Mutation

   RhoA-Q63L

   Promoter

   T7

   Available Since

   July 29, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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9. pTFG011_Spike_Parental_D614G_3xFlag

   Plasmid

   #191571

   Purpose

   SARS-CoV-2 Spike protein under CMV with D614G, C-term 19 amino acid truncation, and 3x FLAG. For expression and pseudotyping lentiviral particles.

   Depositor

   Joshua Leonard

   Article

   Gunnels et al Small. 2022 May;18(19):e2200125. doi: 10

   Insert

   SARS-CoV-2 Spike Protein (S Synthetic)
   

   Tags

   3x FLAG

   Expression

   Mammalian

   Mutation

   D614G mutation. Last 19 amino acids truncated.

   Promoter

   CMV

   Available Since

   July 25, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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10. PX458-SPNS1-sg1

    Plasmid

    #198566

    Purpose

    SPNS1-targeting sgRNA in PX458 vector

    Depositor

    Monther Abu-Remaileh

    Article

    Scharenberg et al Sci Adv. 2023 Apr 21;9(16):eadf8966. doi

    Insert

    SPNS1-sg1 (SPNS1 Human)
    

    Use

    CRISPR

    Expression

    Mammalian

    Available Since

    July 12, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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11. PX458-SPNS1-sg2

    Plasmid

    #198567

    Purpose

    SPNS1-targeting sgRNA in PX458 vector

    Depositor

    Monther Abu-Remaileh

    Article

    Scharenberg et al Sci Adv. 2023 Apr 21;9(16):eadf8966. doi

    Insert

    SPNS1-sg2 (SPNS1 Human)
    

    Use

    CRISPR

    Expression

    Mammalian

    Available Since

    July 12, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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12. pAAV-G12-hFGF1

    Plasmid

    #219554

    Purpose

    hFGF1 expression in mammalian cells. pAAV vector. Reporter plasmid.

    Depositor

    Vladislav Verkhusha

    Article

    Baloban et al Protein Sci. 2024 May;33(5):e4993. doi:

    Insert

    hFGF1 (FGF1 Human)
    

    Use

    AAV

    Expression

    Mammalian

    Promoter

    12xUAS with TATA-box minimal promoter

    Available Since

    May 23, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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13. pSLQ7578 pHR (hU6-crPROX-EFS-PuroR-WPRE)

    Plasmid

    #214882

    Purpose

    Lentiviral vector encoding RfxCas13d targeting PROX guide array

    Depositor

    Stanley Qi

    Article

    Tieu et al Cell. 2024 Feb 29;187(5):1278-1295.e20.

    Insert

    hU6-crPROX-EFS-PuroR-WPRE
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    April 4, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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14. pCRISPR-cBEST-v2-SF14P

    Plasmid

    #209448

    Purpose

    improved pCRISPR-cBEST plasmid with optimized sgRNA cloning site and expression of the sgRNA from the SF14P promoter

    Depositor

    Tilmann Weber

    Article

    Maleckis et al ACS Chem Biol. 2024 Feb 10. doi: 10.1021

    Insert

    Codon optimized APOBEC1-nCas9-UGI fusion protein
    

    Use

    CRISPR and Synthetic Biology

    Promoter

    PtipA; sgRNA expression from SF14P promoter

    Available Since

    March 13, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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15. pCRISPR-cBEST-v2-kasOP*

    Plasmid

    #209447

    Purpose

    improved pCRISPR-cBEST plasmid with optimized sgRNA cloning site and expression of the sgRNA from the kasOP* promoter

    Depositor

    Tilmann Weber

    Article

    Maleckis et al ACS Chem Biol. 2024 Feb 10. doi: 10.1021

    Insert

    Codon optimized APOBEC1-nCas9-UGI fusion protein
    

    Use

    CRISPR and Synthetic Biology

    Promoter

    PtipA; sgRNA expression from kasOP* promoter

    Available Since

    March 13, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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16. pCMV-dCas12a-AID

    Plasmid

    #193647

    Purpose

    Expression of base editor dCas12a-AID in mammalian cells for base editing, along with non-fused EGFP fluorescence

    Depositor

    Liangxue Lai

    Article

    Chen et al Commun Biol. 2022 Nov 2;5(1):1163. doi:

    Insert

    dLbCas12a-hAID, EGFP
    

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    Feb. 20, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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17. pCMV-dCas12a-BE

    Plasmid

    #193648

    Purpose

    Expression of base editor dCas12a-BE in mammalian cells for base editing, along with non-fused EGFP fluorescence

    Depositor

    Liangxue Lai

    Article

    Chen et al Commun Biol. 2022 Nov 2;5(1):1163. doi:

    Insert

    dLbCas12a-rAPOBEC1, EGFP
    

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    Feb. 20, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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18. pCMV-dCas12a-CDA1

    Plasmid

    #193649

    Purpose

    Expression of base editor dCas12a-CDA1 in mammalian cells for base editing, along with non-fused EGFP fluorescence

    Depositor

    Liangxue Lai

    Article

    Chen et al Commun Biol. 2022 Nov 2;5(1):1163. doi:

    Insert

    dLbCas12a-PmCDA1, EGFP
    

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    Feb. 20, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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19. pCMV-dCas12a-eAID

    Plasmid

    #193650

    Purpose

    Expression of base editor dCas12a-eAID in mammalian cells for base editing, along with non-fused EGFP fluorescence

    Depositor

    Liangxue Lai

    Article

    Chen et al Commun Biol. 2022 Nov 2;5(1):1163. doi:

    Insert

    dLbCas12a-eAID, EGFP
    

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    Feb. 20, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. pcDNA3.1-VcnTS-E1015A-E1021A

    Plasmid

    #213417

    Purpose

    Vinculin tension sensor (VcnTS) with both directionally asymmetric, force strengthening (DAFS) variant point mutations (E1015A and E1021A).

    Depositor

    Brenton Hoffman

    Article

    Chirasani et al Nat Commun. 2023 Dec 14;14(1):8300. doi:

    Insert

    VcnTS-E1015A-E1021A (VCL Synthetic, Chicken)
    

    Expression

    Mammalian

    Mutation

    Mutated vinculin glutamic acid 1015 and 1021 to a…

    Promoter

    CMV

    Available Since

    Feb. 15, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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