We narrowed to 15,955 results for: GRN

1. p426_Cas9_gRNA-R-ARS805a

   Plasmid

   #87408

   Purpose

   p426_Cas9_gRNA-ARS805a without ribozyme All-in-one CRISPR plasmid for integrating, deleting, or replacing a gene in S. cerevisiae. High-copy, URA3 plasmid contains human codon-optimized Cas9 and a guide RNA targeting ARS805a sequence TTATTTGAATGATATTTAGT in yeast chromosome 8.

   Depositor

   Aindrila Mukhopadhyay

   Article

   Reider Apel et al Nucleic Acids Res. 2017 Jan 9;45(1):496-

   Insert

   Human Optimized S. pyogenes Cas9 and guide RNA targeting ARS805a
   

   Use

   CRISPR

   Promoter

   ADH1, pTyrosine

   Available Since

   April 5, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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2. p426_Cas9_gRNA-RDS1a

   Plasmid

   #87385

   Purpose

   All-in-one CRISPR plasmid for integrating, deleting, or replacing a gene in S. cerevisiae. High-copy, URA3 plasmid contains human codon-optimized Cas9 and a guide RNA targeting RDS1a sequence ATTCAATACGAAATGTGTGC in yeast chromosome 3

   Depositor

   Aindrila Mukhopadhyay

   Article

   Reider Apel et al Nucleic Acids Res. 2017 Jan 9;45(1):496-

   Insert

   Human Optimized S. pyogenes Cas9 and guide RNA targeting RDS1a
   

   Use

   CRISPR

   Promoter

   ADH1, pTyrosine

   Available Since

   April 5, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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3. AAT_g1 gRNA

   Plasmid

   #86005

   Purpose

   plasmid vector encoding for U6-driven AAT_g1 gRNA

   Depositor

   Tobias Cantz

   Article

   Eggenschwiler et al Sci Rep. 2016 Dec 2;6:38198. doi: 10.103

   Insert

   pU6-AAT_g1 sgRNA
   

   Use

   CRISPR

   Expression

   Mammalian

   Promoter

   pU6

   Available Since

   Feb. 1, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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4. AAT_g2 gRNA

   Plasmid

   #86006

   Purpose

   plasmid vector encoding for U6-driven AAT_g2 gRNA (Z-allele specific)

   Depositor

   Tobias Cantz

   Article

   Eggenschwiler et al Sci Rep. 2016 Dec 2;6:38198. doi: 10.103

   Insert

   pU6-AAT_g2 sgRNA
   

   Use

   CRISPR

   Expression

   Mammalian

   Promoter

   U6

   Available Since

   Feb. 1, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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5. pHU6_Ch5_155183064-gRNA-for

   Plasmid

   #81214

   Purpose

   pHu6-gRNA-NT1_SpecR backbone, gRNA for targeting the 3' region of pCALNL_Ch5 reporter

   Depositor

   David Liu

   Article

   Chaikind et al Nucleic Acids Res. 2016 Aug 11. pii: gkw

   Insert

   hU6 expression of gRNA
   

   Expression

   Mammalian

   Promoter

   U6

   Available Since

   Nov. 4, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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6. pHU6_gRNA_Ch10-for2

   Plasmid

   #81209

   Purpose

   for targeting Ch10 psuedo gix site in PCDH15 gene (five base pairs from the cas9 site and 3' of gix site)

   Depositor

   David Liu

   Article

   Chaikind et al Nucleic Acids Res. 2016 Aug 11. pii: gkw

   Insert

   hU6 expression of gRNA
   

   Expression

   Mammalian

   Promoter

   U6

   Available Since

   Nov. 4, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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7. GK gRNA (BRDN0001146383)

   Plasmid

   #76329

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human GK

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   GK (GK Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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8. GK gRNA (BRDN0001148115)

   Plasmid

   #76326

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human GK

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   GK (GK Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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9. GK gRNA (BRDN0001145307)

   Plasmid

   #76327

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human GK

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   GK (GK Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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10. GK gRNA (BRDN0001146936)

    Plasmid

    #76328

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human GK

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    GK (GK Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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11. pT7-gRNA:Asip

    Plasmid

    #60968

    Purpose

    Expression vector of rat Asip guide RNA

    Depositor

    Tomoji Mashimo

    Article

    Yoshimi et al Nat Commun. 2014 Jun 26;5:4240. doi: 10.

    Insert

    Agouti signaling protein gRNA (Asip Rat)
    

    Use

    CRISPR

    Available Since

    Jan. 5, 2015

    Availability

    Academic Institutions and Nonprofits only

12. pT7-gRNA:kit-1

    Plasmid

    #60969

    Purpose

    Expression vector of rat Kit-1 guide RNA

    Depositor

    Tomoji Mashimo

    Article

    Yoshimi et al Nat Commun. 2014 Jun 26;5:4240. doi: 10.

    Insert

    v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog gRNA (Kit Rat)
    

    Use

    CRISPR

    Available Since

    Jan. 5, 2015

    Availability

    Academic Institutions and Nonprofits only

13. pT7-gRNA:kit-2-1

    Plasmid

    #60970

    Purpose

    Expression vector of rat Kit-2-1 guide RNA

    Depositor

    Tomoji Mashimo

    Article

    Yoshimi et al Nat Commun. 2014 Jun 26;5:4240. doi: 10.

    Insert

    v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog gRNA (Kit Rat)
    

    Use

    CRISPR

    Available Since

    Jan. 5, 2015

    Availability

    Academic Institutions and Nonprofits only

14. pT7-gRNA:kit-2-2

    Plasmid

    #60971

    Purpose

    Expression vector of rat Kit-2-2 guide RNA

    Depositor

    Tomoji Mashimo

    Article

    Yoshimi et al Nat Commun. 2014 Jun 26;5:4240. doi: 10.

    Insert

    v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog gRNA (Kit Rat)
    

    Use

    CRISPR

    Available Since

    Jan. 5, 2015

    Availability

    Academic Institutions and Nonprofits only

15. pU6-pegRNA-GG-acceptor

    Plasmid

    #132777

    Purpose

    Prime editing in mammalian cells

    Depositor

    David Liu

    Article

    Anzalone et al Nature. 2019 Oct 21. pii: 10.1038/s41586

    Insert

    Exchangeable cassette
    

    Expression

    Mammalian

    Mutation

    See manuscript

    Promoter

    U6

    Available Since

    Oct. 21, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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16. pU6_empty-sgRNA(PP7)

    Plasmid

    #232432

    Purpose

    empty gRNA backbone which contains the PP7 aptamer in the scaffold tetraloop

    Depositor

    Gil Westmeyer

    Article

    Geilenkeuser et al Cell. 2025 May 15;188(10):2637-2655.e31.

    Insert

    PP7-tagged sgRNA scaffold driven by human U6 promoter
    

    Use

    CRISPR

    Promoter

    U6

    Available Since

    April 10, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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17. pU6-Osp.gRNA-MS2in

    Plasmid

    #229772

    Purpose

    Contains the U6 promoter and an optimized gRNA backbone inserted with two copies of the MS2 stem loop.

    Depositor

    Yujia Cai

    Article

    Ling et al Nat Nanotechnol. 2025 Apr;20(4):543-553.

    Insert

    gRNA cassette with two MS2 stem loops
    

    Use

    CRISPR

    Expression

    Mammalian

    Promoter

    U6

    Available Since

    Aug. 22, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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18. Dual-sgRNA_hU6-mU6

    Plasmid

    #154194

    Purpose

    Lentiviral expression plasmid for two sgRNAs from a hU6 and a mU6 promoter. The cloning site design allows a one-step cloning strategy of both sgRNAs. Expresses a Thy1.1 marker.

    Depositor

    Anna Obenauf

    Article

    Umkehrer et al Nat Biotechnol. 2020 Jul 27. pii: 10.103

    Type

    Empty backbone

    Use

    Lentiviral

    Expression

    Mammalian

    Available Since

    Dec. 2, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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19. pCFD4-U6:1_U6:3tandemgRNAs

    Plasmid

    #49411

    Purpose

    expression of two gRNAs from Drosophila U6:1 and U6:3

    Depositor

    Simon Bullock

    Article

    Port et al Proc Natl Acad Sci U S A. 2014 Jul 7. pi

    Inserts

    dU6-1:gRNA
    dU6-3:gRNA
    

    Use

    CRISPR

    Expression

    Insect

    Promoter

    dU6-1 and dU6-3

    Available Since

    Jan. 10, 2014

    Availability

    Academic Institutions and Nonprofits only

    

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20. hNTa2-qgRNA-pYJA5

    Plasmid

    #217780

    Purpose

    Non-targeting control 2 qgRNA-pYJA5 plasmid from the T.gonfio library; it can be used as a ready-to-go control and provides the three constant regions for the three-fragment PCRs for qgRNA cloning

    Depositor

    Adriano Aguzzi

    Article

    Yin et al Nat Biomed Eng. 2024 Dec 4. doi: 10.1038

    Insert

    Quadruple sgRNA-expression cassette for nontargeting control for gene activation and epigenetic silencing
    

    Use

    CRISPR, Lentiviral, and Synthetic Biology

    Expression

    Mammalian

    Promoter

    human U6, mouse U6, human H1, human 7SK

    Available Since

    April 17, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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