We narrowed to 14,509 results for: SHR;

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pLKO.1puro-shWillin-A

Plasmid

#40885

Depositor

Paul Reynolds

Article

Angus et al Oncogene. 2012 Jan 12;31(2):238-50. doi:

Insert

shWillin-A (FRMD6 Human)

Use

Lentiviral and RNAi

Expression

Mammalian

Available Since

Nov. 5, 2012

Availability

Academic Institutions and Nonprofits only
pX330_H1.2

Plasmid

#247480

Purpose

Expresses SpCas9 and a sgRNA targeting the human histone H1.2 loci for knock-in.

Depositor

Kazuhiro Maeshima

Article

Shimazoe et al Sci Adv. 2026 Apr 10;12(15):eaec9801. do

Insert

H1.2 (HIST1H1C) (H1-2 Human)

Use

CRISPR

Promoter

U6

Available Since

April 13, 2026

Availability

Academic Institutions and Nonprofits only

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huCofilin K22Q SSR-mRFP

Plasmid

#252617

Purpose

Expresses shRNA resistant human cofilin with K22Q mutation that reduces nuclear uptake and serves as a cofilactin rod reporter

Depositor

James Bamburg

Article

Wiggan et al Dev Cell. 2012 Mar 13;22(3):530-43. doi:

Insert

cofilin 1 (CFL1 Human)

Tags

mRFP

Expression

Mammalian

Mutation

K22Q; silent mutations at nt 67 to 75 in which TC…

Promoter

CMV

Available Since

March 5, 2026

Availability

Industry, Academic Institutions, and Nonprofits

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pscAAV-U6-gIl1r1-CBh-mCherry-SV40late

Plasmid

#249121

Purpose

expression of gIl1r1 and mCherry

Depositor

Matthew Krummel

Article

Kuhn et al J Exp Med. 2026 May 4;223(5):e20251228.

Insert

gIl1r1 (Il1r1 Mouse)

Use

AAV

Promoter

hU6

Available Since

March 4, 2026

Availability

Academic Institutions and Nonprofits only

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pscAAV-U6-gTnfrfs1a-CBh-mCherry-SV40late

Plasmid

#249127

Purpose

expression of gTnfrsf1a and mCherry

Depositor

Matthew Krummel

Article

Kuhn et al J Exp Med. 2026 May 4;223(5):e20251228.

Insert

gTnfrsf1a (Tnfrsf1a Mouse)

Use

AAV

Promoter

hU6

Available Since

March 4, 2026

Availability

Academic Institutions and Nonprofits only

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pscAAV-U6-gCtnnb1-CBh-mCherry-SV40late

Plasmid

#249119

Purpose

expression of gCtnnb1 and mCherry

Depositor

Matthew Krummel

Article

Kuhn et al J Exp Med. 2026 May 4;223(5):e20251228.

Insert

gCtnnb1 (Ctnnb1 Mouse)

Use

AAV

Promoter

hU6

Available Since

March 4, 2026

Availability

Academic Institutions and Nonprofits only

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pX459-TMEM217-gRNA#1

Plasmid

#249417

Purpose

pX459-gRNA#1 targeting the 5′ coding region of human TMEM217

Depositor

Masahito Ikawa

Article

Iida-Norita et al Proc Natl Acad Sci U S A. 2025 Oct 21;12

Insert

TMEM217 (TMEM217 Human)

Use

CRISPR

Available Since

Feb. 25, 2026

Availability

Academic Institutions and Nonprofits only

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pX459-TMEM217-gRNA#2

Plasmid

#249418

Purpose

pX459 plasmid containing gRNA#2 targeting the end of the coding exon of human TMEM217

Depositor

Masahito Ikawa

Article

Iida-Norita et al Proc Natl Acad Sci U S A. 2025 Oct 21;12

Insert

TMEM217 (TMEM217 Human)

Use

CRISPR

Available Since

Feb. 25, 2026

Availability

Academic Institutions and Nonprofits only

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pLV-KLF17-CRa1-MS2

Plasmid

#251117

Purpose

sgRNA1 for KLF17 activation cloned into lenti sgRNA(MS2)_puro backbone

Depositor

Ting Zhou

Article

Wu et al Stem Cell Reports. 2025 Apr 25:102499. d

Insert

sgRNA1 targeting KLF17 promoter (KLF17 Human, Synthetic)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

U6

Available Since

Feb. 3, 2026

Availability

Academic Institutions and Nonprofits only

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lentiCRISPR v2-sgMT1E-1

Plasmid

#251690

Purpose

gRNA to knock out MT1E in mammalian cells

Depositor

Boyi Gan

Article

Lei et al Cancer Cell. 2025 Jun 9;43(6):1076-1092.

Insert

MT1E metallothionein 1E (MT1E Human)

Use

CRISPR and Lentiviral

Available Since

Feb. 3, 2026

Availability

Academic Institutions and Nonprofits only

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lentiCRISPR v2-sgMT1E-2

Plasmid

#251691

Purpose

gRNA to knock out MT1E in mammalian cells

Depositor

Boyi Gan

Article

Lei et al Cancer Cell. 2025 Jun 9;43(6):1076-1092.

Insert

MT1E metallothionein 1E (MT1E Human)

Use

CRISPR and Lentiviral

Available Since

Feb. 3, 2026

Availability

Academic Institutions and Nonprofits only

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lentiCRISPR v2-sgMT1X-1

Plasmid

#251692

Purpose

gRNA to knock out MT1X in mammalian cells

Depositor

Boyi Gan

Article

Lei et al Cancer Cell. 2025 Jun 9;43(6):1076-1092.

Insert

MT1X metallothionein 1X (MT1X Human)

Use

CRISPR and Lentiviral

Available Since

Feb. 3, 2026

Availability

Academic Institutions and Nonprofits only

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lentiCRISPR v2-sgMT1X-2

Plasmid

#251693

Purpose

gRNA to knock out MT1X in mammalian cells

Depositor

Boyi Gan

Article

Lei et al Cancer Cell. 2025 Jun 9;43(6):1076-1092.

Insert

MT1X metallothionein 1X (MT1X Human)

Use

CRISPR and Lentiviral

Available Since

Feb. 3, 2026

Availability

Academic Institutions and Nonprofits only

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pLV-KLF17-CRa2-MS2

Plasmid

#251118

Purpose

sgRNA2 for KLF17 activation cloned into lenti sgRNA(MS2)_puro backbone

Depositor

Ting Zhou

Article

Wu et al Stem Cell Reports. 2025 Apr 25:102499. d

Insert

sgRNA2 targeting KLF17 promoter (KLF17 Human, Synthetic)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

U6

Available Since

Feb. 3, 2026

Availability

Academic Institutions and Nonprofits only

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pLCV2-AAVS1(hU6-sg1-mU6-sg2)-Blast

Plasmid

#208343

Purpose

pLentiCRISPRv2-Blast backbone with two separate sgRNAs against AAVS1. Serves as a negative control by targeting a safe harbor locus.

Depositor

Peter S Nelson

Article

Frank et al eLife 2025

Insert

AAVS1 (AAVS1 Human)

Use

CRISPR and Lentiviral

Promoter

hU6, mU6

Available Since

Jan. 29, 2026

Availability

Academic Institutions and Nonprofits only

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Setd1a gRNA#1

Plasmid

#235250

Purpose

Cas9-mediated knockout of Setd1a in mammalian cells

Depositor

Takeshi Imai

Article

Egashira et al Sci Adv. 2026 Jan 16;12(3):eadw8458. doi

Insert

Setd1a (Setd1a Mouse)

Use

CRISPR

Expression

Mammalian

Available Since

Jan. 22, 2026

Availability

Academic Institutions and Nonprofits only

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Setd1a gRNA#2

Plasmid

#235251

Purpose

Cas9-mediated knockout of Setd1a in mammalian cells

Depositor

Takeshi Imai

Article

Egashira et al Sci Adv. 2026 Jan 16;12(3):eadw8458. doi

Insert

Setd1a (Setd1a Mouse)

Use

CRISPR

Expression

Mammalian

Available Since

Jan. 22, 2026

Availability

Academic Institutions and Nonprofits only

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Setd1a gRNA#3

Plasmid

#235252

Purpose

Cas9-mediated knockout of Setd1a in mammalian cells

Depositor

Takeshi Imai

Article

Egashira et al Sci Adv. 2026 Jan 16;12(3):eadw8458. doi

Insert

Setd1a (Setd1a Mouse)

Use

CRISPR

Expression

Mammalian

Available Since

Jan. 22, 2026

Availability

Academic Institutions and Nonprofits only

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pEHE51

Plasmid

#250522

Purpose

Vector for sgRNA expression in Acinetobacter baumannii (CRISPRi). Modified version of pYDE007 (Plasmid #194152) made Golden Gate compatible (BsaI) for sgRNA oligo insertion.

Depositor

Ralph Isberg

Article

Hamami et al bioRxiv [Preprint]. 2025 Aug 4:2024.01.0

Insert

Two BsaI sites (T-BsaI-BfuI-BsaI-A) inserted between the J23119 promoter and dCas9 handle/gRNA scaffold

Expression

Bacterial

Promoter

J23119

Available Since

Jan. 21, 2026

Availability

Academic Institutions and Nonprofits only

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pCBS-4804

Plasmid

#249320

Purpose

Expresses Non-targeting sgRNA and contains the Repair Template to replace the KanR* on the genome of E. coli MG1655

Depositor

Chase Beisel

Article

Gupta et al Nat Biotechnol. 2025 Sep 4. doi: 10.1038

Insert

nontargeting sgRNA

Expression

Bacterial

Mutation

N/A

Available Since

Jan. 13, 2026

Availability

Academic Institutions and Nonprofits only

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