We narrowed to 18,548 results for: MUT

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pTH394-SUP45-L34S

Plasmid

#29373

Depositor

Tobias von der Haar

Article

Merritt et al Nucleic Acids Res. 2010 Sep . 38(16):547

Insert

SUP45 gene encoding translation release factor 1 from S. cerevisiae (SUP45 Budding Yeast)

Expression

Yeast

Mutation

L34S mutant gene (corresponding to the sup45-36ts…

Available Since

May 23, 2011

Availability

Academic Institutions and Nonprofits only
pTH355-SUP45-T55A

Plasmid

#29377

Depositor

Tobias von der Haar

Article

Merritt et al Nucleic Acids Res. 2010 Sep . 38(16):547

Insert

SUP45 gene encoding translation release factor 1 from S. cerevisiae (SUP45 Budding Yeast)

Expression

Yeast

Mutation

T55A mutant gene including genomic sequence 1432 …

Available Since

May 23, 2011

Availability

Academic Institutions and Nonprofits only
pTH373-SUP45-S61A

Plasmid

#29380

Depositor

Tobias von der Haar

Article

Merritt et al Nucleic Acids Res. 2010 Sep . 38(16):547

Insert

SUP45 gene encoding translation release factor 1 from S. cerevisiae (SUP45 Budding Yeast)

Expression

Yeast

Mutation

S61A mutant gene including genomic sequence 1432 …

Available Since

May 23, 2011

Availability

Academic Institutions and Nonprofits only
pTH401-SUP45-R65C

Plasmid

#29381

Depositor

Tobias von der Haar

Article

Merritt et al Nucleic Acids Res. 2010 Sep . 38(16):547

Insert

SUP45 gene encoding translation release factor 1 from S. cerevisiae (SUP45 Budding Yeast)

Expression

Yeast

Mutation

R65C mutant gene (corresponding to the sup45-3 al…

Available Since

May 23, 2011

Availability

Academic Institutions and Nonprofits only
pTH627-SUP45-V107D

Plasmid

#29382

Depositor

Tobias von der Haar

Article

Merritt et al Nucleic Acids Res. 2010 Sep . 38(16):547

Insert

SUP45 gene encoding translation release factor 1 from S. cerevisiae (SUP45 Budding Yeast)

Expression

Yeast

Mutation

V107D mutant gene including genomic sequence 1432…

Available Since

May 23, 2011

Availability

Academic Institutions and Nonprofits only
pTH441-SUP45-K175T

Plasmid

#29384

Depositor

Tobias von der Haar

Article

Merritt et al Nucleic Acids Res. 2010 Sep . 38(16):547

Insert

SUP45 gene encoding translation release factor 1 from S. cerevisiae (SUP45 Budding Yeast)

Expression

Yeast

Mutation

K175T mutant gene including genomic sequence 1432…

Available Since

May 23, 2011

Availability

Academic Institutions and Nonprofits only
pTH442-SUP45-K176T

Plasmid

#29385

Depositor

Tobias von der Haar

Article

Merritt et al Nucleic Acids Res. 2010 Sep . 38(16):547

Insert

SUP45 gene encoding translation release factor 1 from S. cerevisiae (SUP45 Budding Yeast)

Expression

Yeast

Mutation

K176T mutant gene including genomic sequence 1432…

Available Since

May 23, 2011

Availability

Academic Institutions and Nonprofits only
pTH444-SUP45-G181A

Plasmid

#29387

Depositor

Tobias von der Haar

Article

Merritt et al Nucleic Acids Res. 2010 Sep . 38(16):547

Insert

SUP45 gene encoding translation release factor 1 from S. cerevisiae (SUP45 Budding Yeast)

Expression

Yeast

Mutation

G181A mutant gene including genomic sequence 1432…

Available Since

May 23, 2011

Availability

Academic Institutions and Nonprofits only
pTH374-SUP45-R62A

Plasmid

#29391

Depositor

Tobias von der Haar

Article

Merritt et al Nucleic Acids Res. 2010 Sep . 38(16):547

Insert

SUP45 gene encoding translation release factor 1 from S. cerevisiae (SUP45 Budding Yeast)

Expression

Yeast

Mutation

R62A mutant gene including genomic sequence 1432 …

Available Since

May 23, 2011

Availability

Academic Institutions and Nonprofits only
pTH356-SUP45-T295A

Plasmid

#29389

Depositor

Tobias von der Haar

Article

Merritt et al Nucleic Acids Res. 2010 Sep . 38(16):547

Insert

SUP45 gene encoding translation release factor 1 from S. cerevisiae (SUP45 Budding Yeast)

Expression

Yeast

Mutation

T295A mutant gene including genomic sequence 1432…

Available Since

May 5, 2011

Availability

Academic Institutions and Nonprofits only
pTH393-SUP45-T357A

Plasmid

#29392

Depositor

Tobias von der Haar

Article

Merritt et al Nucleic Acids Res. 2010 Sep . 38(16):547

Insert

SUP45 gene encoding translation release factor 1 from S. cerevisiae (SUP45 Budding Yeast)

Expression

Yeast

Mutation

T357A mutant gene including genomic sequence 1432…

Available Since

May 5, 2011

Availability

Academic Institutions and Nonprofits only
pTH357-SUP45-T388A

Plasmid

#29393

Depositor

Tobias von der Haar

Article

Merritt et al Nucleic Acids Res. 2010 Sep . 38(16):547

Insert

SUP45 gene encoding translation release factor 1 from S. cerevisiae (SUP45 Budding Yeast)

Expression

Yeast

Mutation

T388A mutant gene including genomic sequence 1432…

Available Since

May 5, 2011

Availability

Academic Institutions and Nonprofits only
pTH363-SUP45-F401Y

Plasmid

#29394

Depositor

Tobias von der Haar

Article

Merritt et al Nucleic Acids Res. 2010 Sep . 38(16):547

Insert

SUP45 gene encoding translation release factor 1 from S. cerevisiae (SUP45 Budding Yeast)

Expression

Yeast

Mutation

F401Y mutant gene including genomic sequence 1432…

Available Since

May 5, 2011

Availability

Academic Institutions and Nonprofits only
pTH364-SUP45-Y410F

Plasmid

#29395

Depositor

Tobias von der Haar

Article

Merritt et al Nucleic Acids Res. 2010 Sep . 38(16):547

Insert

SUP45 gene encoding translation release factor 1 from S. cerevisiae (SUP45 Budding Yeast)

Expression

Yeast

Mutation

Y410F mutant gene including genomic sequence 1432…

Available Since

May 5, 2011

Availability

Academic Institutions and Nonprofits only
23SrRNA.RAV12(wt).2508-2580.GAAAC.G2553U

Plasmid

#26191

Depositor

David McKay

Article

Hardin et al J Mol Biol. 2010 Sep 17;402(2):412-27. d

Insert

23S ribosomal RNA fragment (modified) with G2553U mutation

Expression

Bacterial

Mutation

fragment 2508-2580 of E. coli rRNA, with nucleoti…

Available Since

Oct. 28, 2010

Availability

Academic Institutions and Nonprofits only

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pcDNA3-S33Y Beta-catenin

Plasmid

#19286

Purpose

Mammalian expression of human beta-catenin with Flag tag and S33Y mutation

Depositor

Eric Fearon

Article

Kolligs et al Mol Cell Biol. 1999 Aug . 19(8):5696-706

Insert

beta-catenin (CTNNB1 Human)

Tags

Flag

Expression

Mammalian

Mutation

S33Y (presumptive GSK3β phosphorylation site)

Available Since

Sept. 15, 2008

Availability

Academic Institutions and Nonprofits only

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LentiV_Neo_SIK3_CR_K95M

Plasmid

#108106

Purpose

Lentiviral expression plasmid of human SIK3 cDNA (CRISPR-resistant silent mutation & kinase-dead mutation) with neomycin resistance gene

Depositor

Christopher Vakoc

Article

Tarumoto et al Mol Cell. 2018 Feb 28. pii: S1097-2765(1

Insert

SIK3 (SIK3 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Mutation

change guanine 501 to cytosine (silent mutation),…

Promoter

EFS promoter

Available Since

April 5, 2018

Availability

Academic Institutions and Nonprofits only

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pcDNA3-FLAG-MTOR-E1799K

Plasmid

#69009

Purpose

activating MTOR mutation

Depositor

David Sabatini

Article

Grabiner et al Cancer Discov. 2014 May;4(5):554-63. doi

Insert

MTOR-E1799K (MTOR Human)

Tags

FLAG

Expression

Mammalian

Mutation

change Glutamate 1799 to Lysine

Available Since

Dec. 17, 2015

Availability

Academic Institutions and Nonprofits only

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pcDNA3-FLAG-MTOR-F1888L

Plasmid

#69010

Purpose

activating MTOR mutation

Depositor

David Sabatini

Article

Grabiner et al Cancer Discov. 2014 May;4(5):554-63. doi

Insert

MTOR-F1888L (MTOR Human)

Tags

FLAG

Expression

Mammalian

Mutation

change Phenylalanine 1888 to Leucine

Available Since

Jan. 20, 2016

Availability

Academic Institutions and Nonprofits only
pKLV-EF1aGFP2AKAT7(E508Q)-W

Plasmid

#159293

Purpose

Lentiviral vector expressing GFP and KAT7 (gRNA-resistant, E508Q mutant) driven by human EF1a promoter

Depositor

Kosuke Yusa

Article

Au et al Leukemia. 2021 Apr;35(4):1012-1022. doi:

Insert

KAT7 E508Q

Use

Lentiviral

Expression

Mammalian

Mutation

CRISPR sites mutated (gRNA ID. 5 and A10) and E50…

Promoter

human EF1a promoter

Available Since

Dec. 3, 2020

Availability

Academic Institutions and Nonprofits only

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EGFR L858R

Plasmid

#11012

Purpose

Retroviral construct for expressing human EGFR with L858R mutation in human cells

Depositor

Matthew Meyerson

Article

Greulich et al PLoS Med. 2005 Oct 4. 2(11):e313.

Insert

EGFR L858R (EGFR Human)

Use

Retroviral

Expression

Mammalian

Mutation

L858R (tumor-derived)

Available Since

Aug. 4, 2006

Availability

Academic Institutions and Nonprofits only

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pET21a Lm-iPGM

Plasmid

#180242

Purpose

Bacterial expression plasmid for production of recombinant Leishmania mexicana iPGM His10

Depositor

James Inglese

Article

van Neer et al ACS Chem Biol. 2022 Aug 19;17(8):2284-22

Insert

Leishmania mexicana iPGM-10His

Tags

His

Expression

Bacterial

Promoter

T7

Available Since

Sept. 19, 2022

Availability

Academic Institutions and Nonprofits only

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pCMV/myc/mito-hOGG1

Plasmid

#18706

Depositor

David Sidransky

Article

Chatterjee et al BMC Cancer. 2006 Oct 3;6:235. doi: 10.11

Insert

8-oxoguanine DNA glycosylase (OGG1 Human)

Expression

Mammalian

Mutation

N/A

Available Since

July 3, 2008

Availability

Academic Institutions and Nonprofits only
pZVsE_SC12

Plasmid

#219722

Purpose

Zika virus stable E dimer with fusion loop mutation and increased expression

Depositor

Brian Kuhlman

Article

Phan et al J Biol Chem. 2022 Jul;298(7):102079. doi

Insert

ZKV sE SC12

Tags

8xHis and human serum albumin (HSA)

Expression

Mammalian

Mutation

G106D, A264W, T267R, S286W, S287P, G29K, A25M

Available Since

May 17, 2024

Availability

Academic Institutions and Nonprofits only

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pAAV-FLEX-SaCas9-U6-sgGrin1

Plasmid

#124852

Purpose

Mutagenesis of Grin1

Depositor

Larry Zweifel

Article

Hunker et al Cell Rep. 2020 Mar 24;30(12):4303-4316.e

Insert

Grin1 (Grin1 Mouse)

Use

AAV, CRISPR, and Mouse Targeting

Available Since

May 3, 2019

Availability

Academic Institutions and Nonprofits only

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pD3sE_SC12

Plasmid

#219720

Purpose

DV3 E dimer with fusion loop mutation and increased expression

Depositor

Brian Kuhlman

Article

Phan et al J Biol Chem. 2022 Jul;298(7):102079. doi

Insert

DV3 sE SC12

Tags

8xHis and human serum albumin (HSA)

Expression

Mammalian

Mutation

G106D, A257W, T260R, F277W, A278P, G29K, T33V, A3…

Available Since

May 17, 2024

Availability

Academic Institutions and Nonprofits only

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pD4sE_SC12

Plasmid

#219721

Purpose

DV4 stable E dimer with fusion loop mutation and increased expression

Depositor

Brian Kuhlman

Article

Phan et al J Biol Chem. 2022 Jul;298(7):102079. doi

Insert

DV4 sE SC12

Tags

8xHis and human serum albumin (HSA)

Expression

Mammalian

Mutation

G106D, A259W, S262R, F279W, A280P, G29K, T33V, A2…

Available Since

May 17, 2024

Availability

Academic Institutions and Nonprofits only

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pD1sE_SC12

Plasmid

#219718

Purpose

DV1 E dimer with fusion loop mutation and increased expression

Depositor

Brian Kuhlman

Article

Phan et al J Biol Chem. 2022 Jul;298(7):102079. doi

Insert

DV1 sE SC12

Tags

8xHis and human serum albumin (HSA)

Expression

Mammalian

Mutation

G106D, A259W, T262R, F279W, A280P, S29K, T33V, A2…

Available Since

May 14, 2024

Availability

Academic Institutions and Nonprofits only

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pD2sE_SC12

Plasmid

#219719

Purpose

DV2 stable E dimer with fusion loop mutation and increased expression

Depositor

Brian Kuhlman

Article

Phan et al J Biol Chem. 2022 Jul;298(7):102079. doi

Insert

DV2 sE SC12

Tags

8xHis and human serum albumin (HSA)

Expression

Mammalian

Mutation

G106D, A259W, T262R, F279W, T280P, S29K, T33V, A2…

Available Since

May 17, 2024

Availability

Academic Institutions and Nonprofits only

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MO91-dCas9-AID(P182X)

Plasmid

#83260

Purpose

Expresses fusion of human codon-optimized S. pyogenes dCas9 (D10A, H840A ) protein with a human AID mutant protein (p182X). MSCV Retroviral backbone.

Depositor

Xing Chang

Article

Ma et al Nat Methods. 2016 Dec;13(12):1029-1035.

Insert

dCas9-AID P182X

Use

Retroviral

Tags

3xFLAG-NLS and FLAG

Expression

Mammalian

Mutation

D10A and H840A in Cas9; P182X in AID

Promoter

MSCV

Available Since

May 4, 2017

Availability

Academic Institutions and Nonprofits only