Addgene

This website uses cookies to ensure you get the best experience. By continuing to use this site, you agree to the use of cookies.

Please note: Your browser does not support the features used on Addgene's website. You may not be able to create an account or request plasmids through this website until you upgrade your browser. Learn more

Please note: Your browser does not fully support some of the features used on Addgene's website. If you run into any problems registering, depositing, or ordering please contact us at [email protected]. Learn more

We narrowed to 158 results for: mecp2

Showing: 61 - 80 of 158 results

Results per page:

pDEST-hMeCP2-GFP-R270X

Plasmid

#48079

Purpose

Mammalian expression of GFP tagged MeCP2-R270X

Depositor

Huda Zoghbi

Article

Baker et al Cell. 2013 Feb 28;152(5):984-96. doi: 10

Insert

Methyl-CpG Binding Protein 2 (Rett Syndrome) (MECP2 Human)

Use

Tags

GFP

Expression

Mammalian

Mutation

expresses AT-Hook R270X

Promoter

CMV

Availability

Academic Institutions and Nonprofits only

Enlarge
pDEST-hMeCP2-GFP-G273X

Plasmid

#48080

Purpose

Mammalian expression of GFP tagged MeCP2-G273X

Depositor

Huda Zoghbi

Article

Baker et al Cell. 2013 Feb 28;152(5):984-96. doi: 10

Insert

Methyl-CpG Binding Protein 2 (Rett Syndrome) (MECP2 Human)

Use

Tags

GFP

Expression

Mammalian

Mutation

expresses AT-Hook G273X

Promoter

CMV

Availability

Academic Institutions and Nonprofits only

Enlarge
pCMX-Gal4-hMeCP2-R270X

Plasmid

#48083

Purpose

Mammalian expression of Gal4 tagged MeCP2-R270X

Depositor

Huda Zoghbi

Article

Baker et al Cell. 2013 Feb 28;152(5):984-96. doi: 10

Insert

Methyl-CpG Binding Protein 2 (Rett Syndrome) (MECP2 Human)

Use

Tags

Gal4

Expression

Mammalian

Mutation

expresses AT-Hook R270X

Promoter

Availability

Academic Institutions and Nonprofits only
pCMX-Gal4-hMeCP2-G273X

Plasmid

#48084

Purpose

Mammalian expression of Gal4 tagged MeCP2-G273X

Depositor

Huda Zoghbi

Article

Baker et al Cell. 2013 Feb 28;152(5):984-96. doi: 10

Insert

Methyl-CpG Binding Protein 2 (Rett Syndrome) (MECP2 Human)

Use

Tags

Gal4

Expression

Mammalian

Mutation

expresses AT-Hook G273X

Promoter

Availability

Academic Institutions and Nonprofits only
pCMX-Gal4-hMeCP2-R111G

Plasmid

#48085

Purpose

Mammalian expression of Gal4 tagged MeCP2-WT-R111G

Depositor

Huda Zoghbi

Article

Baker et al Cell. 2013 Feb 28;152(5):984-96. doi: 10

Insert

Methyl-CpG Binding Protein 2 (Rett Syndrome) (MECP2 Human)

Use

Tags

Gal4

Expression

Mammalian

Mutation

R111G mutant MeCP2

Promoter

Availability

Academic Institutions and Nonprofits only
PB-TRE-dCas9-KRAB-MeCP2

Plasmid

#122267

Purpose

SP-dCas9-KRAB-MeCP2 with doxycycline-inducible expression

Depositor

Andrea Califano

Article

Tan et al bioRxiv 2021.06.28.449297

Insert

dCas9-KRAB-MeCP2

Use

Tags

dCas9-KRAB-MeCP2

Expression

Mammalian

Mutation

Promoter

Availability

Academic Institutions and Nonprofits only

Enlarge
pAAV-CAG-GFP-mirMecp2

Plasmid

#163704

Purpose

pAAV plasmid to induce expression of micro-RNA targeted against mouse Mecp2 and EGFP

Depositor

Michisuke Yuzaki

Article

Ito-Ishida et al J Neurosci. 2020 Nov 4;40(45):8746-8766.

Insert

mirMecp2 and EGFP (Mecp2 Mouse, Aequorea victoria)

Use

AAV

Tags

Expression

Mutation

Promoter

CAG

Availability

Academic Institutions and Nonprofits only

Enlarge
rAAV-U6-MeCP2shRNA-CamKIIa-mCherry

Plasmid

#169704

Purpose

MeCP2 Knockdown

Depositor

Ana Oliveira

Article

Gulmez Karaca et al Neurobiol Learn Mem. 2018 Mar;149:84-97.

Insert

shRNA against MeCp2 (Mecp2 Mouse)

Use

AAV

Tags

Expression

Mutation

Promoter

Availability

Academic Institutions and Nonprofits only

Enlarge
Anti-MECP2 [N227/21R]

Plasmid

#177518

Purpose

Mammalian Expression Plasmid of anti-MECP2 (Human). Derived from hybridoma N227/21.

Depositor

James Trimmer

Article

Mitchell et al Sci Rep. 2023 Sep 27;13(1):16200. doi: 1

Insert

anti-MECP2 (Homo sapiens) recombinant mouse monoclonal antibody (MECP2 Mouse)

Use

Tags

Expression

Mammalian

Mutation

Promoter

Dual CMV

Availability

Academic Institutions and Nonprofits only

Enlarge
pOTTC1124 - pAAV MeCP2 SpCas9(D10A)

Plasmid

#112719

Purpose

An AAV vector that expresses SpCas9 nickase under a neuronal cell promoter

Depositor

Brandon Harvey

Article

Back et al Neuron. 2019 Feb 8. pii: S0896-6273(19)3

Insert

SpCas9

Use

AAV

Tags

Expression

Mutation

D10A

Promoter

Mecp2

Availability

Academic Institutions and Nonprofits only

Enlarge
pCMX-Gal4-hMeCP2-R270X-R111G

Plasmid

#48086

Purpose

Mammalian expression of Gal4 tagged MeCP2-R270X-R111G

Depositor

Huda Zoghbi

Article

Baker et al Cell. 2013 Feb 28;152(5):984-96. doi: 10

Insert

Methyl-CpG Binding Protein 2 (Rett Syndrome) (MECP2 Human)

Use

Tags

Gal4

Expression

Mammalian

Mutation

R111G mutant MeCP2, expresses AT-hook R270X

Promoter

Availability

Academic Institutions and Nonprofits only
pCMX-Gal4-hMeCP2-G273X-R111G

Plasmid

#48087

Purpose

Mammalian expression of Gal4 tagged MeCP2-G273X-R111G

Depositor

Huda Zoghbi

Article

Baker et al Cell. 2013 Feb 28;152(5):984-96. doi: 10

Insert

Methyl-CpG Binding Protein 2 (Rett Syndrome) (MECP2 Human)

Use

Tags

Gal4

Expression

Mammalian

Mutation

R111G mutant MeCP2, expresses AT-hook G273X

Promoter

Availability

Academic Institutions and Nonprofits only
pGEX-5x3-hMeCP2-delN256-R270X

Plasmid

#48089

Purpose

Bacterial expression of GST tagged AT-Hook2-R270X

Depositor

Huda Zoghbi

Article

Baker et al Cell. 2013 Feb 28;152(5):984-96. doi: 10

Insert

Methyl-CpG Binding Protein 2 (Rett Syndrome) (MECP2 Human)

Use

Tags

GST

Expression

Bacterial

Mutation

deleted the N-terminal 256 codons, expresses AT-H…

Promoter

Availability

Academic Institutions and Nonprofits only
pGEX-5x3-hMeCP2-delN256-G273X

Plasmid

#48090

Purpose

Bacterial expression of GST tagged AT-Hook2-G273X

Depositor

Huda Zoghbi

Article

Baker et al Cell. 2013 Feb 28;152(5):984-96. doi: 10

Insert

Methyl-CpG Binding Protein 2 (Rett Syndrome) (MECP2 Human)

Use

Tags

GST

Expression

Bacterial

Mutation

deleted the N-terminal 256 codons, expresses AT-H…

Promoter

Availability

Academic Institutions and Nonprofits only
lenti SYN-dCas9-KRAB-MeCP2

Plasmid

#155365

Purpose

Expresses dCas9-KRAB-MeCP2 fusion driven by human SYN promoter

Depositor

Jeremy Day

Article

Duke et al Front Genome Ed. 2020 Sep 15;2:9. doi: 1

Insert

dCas9-KRAB-MeCP2

Use

CRISPR and Lentiviral

Tags

3x FLAG and 7x His

Expression

Mammalian

Mutation

Promoter

SYN

Availability

Academic Institutions and Nonprofits only

Enlarge
pAAV-pMecp2-SaCas9-pU6-sgRNA

Plasmid

#159173

Purpose

Vector A encodes pAAV-pMecp2-SaCas9-spA-pU6-sgRNA (BsaI) transgenes for AAV packaging and expression of SaCas9-sgRNA in neurons

Depositor

Chung Tin

Article

Lau et al Mol Ther Nucleic Acids. 2019 Jun 7;16:63

Insert

SaCas9

Use

AAV and CRISPR

Tags

Expression

Mammalian

Mutation

Promoter

pMecp2

Availability

Academic Institutions and Nonprofits only

Enlarge
pAAV-pMecp2-dSaCas9-pU6-sgRNA

Plasmid

#159174

Purpose

Vector B encodes pAAV-pMecp2-dSaCas9-spA-pU6-sgRNA (BsaI) transgenes for AAV packaging and expression of dSaCas9-sgRNA in neurons

Depositor

Chung Tin

Article

Lau et al Mol Ther Nucleic Acids. 2019 Jun 7;16:63

Insert

dSaCas9

Use

AAV and CRISPR

Tags

Expression

Mammalian

Mutation

Promoter

pMecp2

Availability

Academic Institutions and Nonprofits only

Enlarge
pAAV-hSyn-DIO-hMECP2-cycle3GFP

Plasmid

#163706

Purpose

pAAV plasmid for Cre-dependent expression of human MECP2 fused with cycle3 GFP under Syn promoter

Depositor

Michisuke Yuzaki

Article

Ito-Ishida et al J Neurosci. 2020 Nov 4;40(45):8746-8766.

Insert

hMECP2-cycle3GFP (MECP2 Human, Aequorea victoria)

Use

AAV

Tags

Expression

Mutation

Promoter

hSyn

Availability

Academic Institutions and Nonprofits only

Enlarge
Lenti-EF1alpha-dCas9-KRAB-MeCP2_Hygro

Plasmid

#192664

Purpose

3rd generation lenti vector encoding dCas9-KRAB-MeCP2 with 2A Hygro resistance marker

Depositor

Jeffrey Miner

Insert

dCas9-KRAB-MeCP2

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

D10A, D839A, H840A and N863A in Cas9

Promoter

EF1a

Availability

Academic Institutions and Nonprofits only

Enlarge
lenti GFAABC1D-dCas9-KRAB-MeCP2

Plasmid

#194701

Purpose

Expresses dCas9-KRAB-MeCP2 in Astrocytes

Depositor

Timothy Jarome

Article

Farrell et al Learn Mem. 2023 Mar 15;30(3):70-73. doi:

Insert

GFAABC1D promoter

Use

CRISPR and Lentiviral

Tags

3xFLAG

Expression

Mammalian

Mutation

None

Promoter

GFAABC1D

Availability

Academic Institutions and Nonprofits only

Enlarge