384 results

1. mCRISPRi-v2, genome-wide, top 5 sgRNAs/gene

   Pooled Library

   #83987

   Purpose

   Version 2 of the mouse CRISPRi genome wide library

   Depositor

   Jonathan Weissman

   Article

   Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

   Use

   Lentiviral

   Available Since

   Nov. 15, 2016

   Availability

   Academic Institutions and Nonprofits only

2. Mouse Brie kinome pooled library, guides 1-4 in lentiGuide-Puro backbone

   Pooled Library

   #75316

   Purpose

   Mouse sgRNA library in backbone lentiGuide-Puro targeting 713 kinase genes and containing 2,852 unique sgRNAs along with 100 non-targeting controls

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Available Since

   June 27, 2016

   Availability

   Academic Institutions and Nonprofits only

3. Bassik lab Human CRISPR-Cas9 Deletion Library - Apoptosis and cancer

   Pooled Library

   #101926

   Purpose

   Bassik lab Human CRISPR-Cas9 Deletion Library - Apoptosis and cancer. Coexpresses mCherry.

   Depositor

   Michael Bassik

   Article

   Morgens et al Nat Commun. 2017 May 5;8:15178. doi: 10.

   Expression

   Mammalian

   Use

   CRISPR

   Available Since

   May 23, 2018

   Availability

   Academic Institutions and Nonprofits only

4. hCRISPRa-v2, Membrane Proteins (h6), top 5 sgRNAs/gene

   Pooled Library

   #83985

   Purpose

   Human CRISPRa Pooled Library targeting membrane proteins

   Depositor

   Jonathan Weissman

   Article

   Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

   Available Since

   Jan. 12, 2017

   Availability

   Academic Institutions and Nonprofits only

5. hCRISPRi-v2, Membrane Proteins (h6), top 5 sgRNAs/gene

   Pooled Library

   #83976

   Purpose

   Human CRISPRi Pooled Library targeting membrane proteins

   Depositor

   Jonathan Weissman

   Article

   Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

   Available Since

   Dec. 14, 2016

   Availability

   Academic Institutions and Nonprofits only

6. psgRNA Library

   Pooled Library

   #115927

   Purpose

   Genome-wide knockdown of E. coli genes

   Depositor

   David Bikard

   Article

   Cui et al Nat Commun. 2018 May 15;9(1):1912. doi:

   Expression

   Bacterial

   Species

   Escherichia coli

   Use

   CRISPR

   Available Since

   June 6, 2019

   Availability

   Academic Institutions and Nonprofits only

7. Mouse lipid metabolism knockout library

   Pooled Library

   #206248

   Purpose

   The lipid metabolism library contains guide RNAs against 295 genes targeting mouse genes encoding enzymes that directly impact lipid metabolism.

   Depositor

   Kivanc Birsoy

   Article

   Soula et al Nature. 2024 Aug 7. doi: 10.1038/s41586-

   Use

   CRISPR and Lentiviral

   Available Since

   Aug. 29, 2024

   Availability

   Academic Institutions and Nonprofits only

8. SPLINTR mCHERRY v1

   Pooled Library

   #179775

   Purpose

   SPLINTR (Single-cell Profiling and LINeage TRacing) is a high diversity lentiviral barcode library for tracing clonal lineages using bulk and single-cell readouts.

   Depositor

   Mark Dawson

   Article

   Fennell et al Nature. 2022 Jan;601(7891):125-131. doi:

   Expression

   Mammalian

   Use

   Lentiviral

   Available Since

   May 11, 2022

   Availability

   Academic Institutions and Nonprofits only

9. pre-associated oBC-minP-GFP-mBC backbone (p043)

   Pooled Library

   #194098

   Purpose

   pre-associated oBC-minP-GFP-mBC backbone (p043), can directly be used to deposit library of regulatory elements

   Depositor

   Jay Shendure

   Article

   Lalanne et al bioRxiv 2022.12.10.519236

   Expression

   Bacterial and Mammalian

   Use

   RNAi

   Available Since

   April 3, 2024

   Availability

   Academic Institutions and Nonprofits only

10. BARBEKO sgRNA library

    Pooled Library

    #174163

    Purpose

    iBARed cytosine Base Editing-mediated gene KnockOut (BARBEKO) sgRNA library; This library leverages CRISPR cytosine base editors for genome-scale knockout screens.

    Depositor

    Wensheng Wei

    Article

    Xu et al Nat Biotechnol. 2021 Jun 21. pii: 10.103

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available Since

    Aug. 31, 2021

    Availability

    Academic Institutions and Nonprofits only