We narrowed to 285 results for: Spr
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Pooled Library#209735PurposeCHyMErA Cas12a Nuclease Optimization hgRNA Libraries allows assessment and comparison of the efficacy of different AsCas12a nucleases in the context of the Cas9-Cas12a CHyMErA system.DepositorExpressionMammalianUseCRISPR and LentiviralAvailable SinceJune 20, 2024AvailabilityAcademic Institutions and Nonprofits only
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CHyMErA Large-Scale Exon Deletion hgRNA Library
Pooled Library#209736PurposeCHyMErA Exon Deletion hgRNA Library allows identification of frame-preserving exons that affect cell fitness in human cells using the CHyMErA screening platform.DepositorExpressionMammalianUseCRISPR and LentiviralAvailable SinceJune 20, 2024AvailabilityAcademic Institutions and Nonprofits only -
plIG-123_HA-GD2-28z_CAR_TF_Library
Pooled Library#207478PurposeHA-GD2-28z CAR in combination with 100 transcription factors (and related proteins) and 2 controls (GFP/RFP). Library can be used to generate HDR templates for modular pooled knockin (ModPoKI) into thDepositorSpeciesHomo sapiensUseCRISPRAvailable SinceJan. 26, 2024AvailabilityAcademic Institutions and Nonprofits only -
plIG-128_HA-GD2-28z_CAR_TFxTF_Library
Pooled Library#207480PurposeHA-GD2-28z CAR in combination with ~10,000 transcription factor combinations (and related proteins) and controls (GFP/RFP combinations). Library can be used to generate HDR templates for modular pooleDepositorUseCRISPRAvailable SinceJan. 26, 2024AvailabilityAcademic Institutions and Nonprofits only -
plIG-106_NY-ESO-1_TCR_SR_Library
Pooled Library#207474PurposeNY-ESO-1 TCR in combination with 129 surface receptors and 2 controls (GFP/RFP). Library can be used to generate HDR templates for modular pooled knockin (ModPoKI) into the TRAC locus of human T cellsDepositorSpeciesHomo sapiensUseCRISPRAvailable SinceJan. 26, 2024AvailabilityAcademic Institutions and Nonprofits only -
plIG-107_NY-ESO-1_TCR_TF_Library
Pooled Library#207475PurposeNY-ESO-1 TCR in combination with 100 transcription factors (and related proteins) and 2 controls (GFP/RFP). Library can be used to generate HDR templates for modular pooled knockin (ModPoKI) into theDepositorSpeciesHomo sapiensUseCRISPRAvailable SinceJan. 26, 2024AvailabilityAcademic Institutions and Nonprofits only -
plIG-109_CD19-BBz_CAR_SR_Library
Pooled Library#207476PurposeCD19-BBz CAR in combination with 129 surface receptors and 2 controls (GFP/RFP). Library can be used to generate HDR templates for modular pooled knockin (ModPoKI) into the TRAC locus of human T cellsDepositorUseCRISPRAvailable SinceJan. 26, 2024AvailabilityAcademic Institutions and Nonprofits only -
plIG-110_CD19-BBz_CAR_TF_Library
Pooled Library#207477PurposeCD19-BBz CAR in combination with 100 transcription factors (and related proteins) and 2 controls (GFP/RFP). Library can be used to generate HDR templates for modular pooled knockin (ModPoKI) into theDepositorSpeciesHomo sapiensUseCRISPRAvailable SinceJan. 26, 2024AvailabilityAcademic Institutions and Nonprofits only -
plIG-124_HA-GD2-28z_CAR_SR_Library
Pooled Library#207479PurposeHA-GD2-28z CAR in combination with 129 surface receptors and 2 controls (GFP/RFP). Library can be used to generate HDR templates for modular pooled knockin (ModPoKI) into the TRAC locus of human T celDepositorSpeciesHomo sapiensUseCRISPRAvailable SinceJan. 26, 2024AvailabilityAcademic Institutions and Nonprofits only -
plIG-132_CD19-28z_CAR_TF_and_SR_Library
Pooled Library#207481PurposeCD19-28z CAR in combination with 129 surface receptors, 100 transcription factors (and related proteins) and 2 controls (GFP/RFP). Library can be used to generate HDR templates for modular pooled knocDepositorSpeciesHomo sapiensUseCRISPRAvailable SinceJan. 26, 2024AvailabilityAcademic Institutions and Nonprofits only -
SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library N501Y Tile 2 (positions 437-527)
Pooled Library#174296PurposeThis library contains mutations to SARS-CoV-2 Spike RBD N501Y variant in which all surface exposed residues on S RBD (Tile 2, positions 437-527) were mutated to every other amino acid.DepositorExpressionYeastAvailable SinceSept. 13, 2021AvailabilityAcademic Institutions and Nonprofits only -
SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library N501Y Tile 1 (positions 333-436)
Pooled Library#174295PurposeThis library contains mutations to SARS-CoV-2 Spike RBD N501Y variant in which all surface exposed residues on S RBD (Tile 1, positions 333-436) were mutated to every other amino acid.DepositorExpressionYeastAvailable SinceSept. 13, 2021AvailabilityAcademic Institutions and Nonprofits only -
SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library E484K Tile 2 (positions 437-527)
Pooled Library#174294PurposeThis library contains mutations to SARS-CoV-2 Spike RBD E484K variant in which all surface exposed residues on S RBD (Tile 2, positions 437-527) were mutated to every other amino acid.DepositorExpressionYeastAvailable SinceSept. 13, 2021AvailabilityAcademic Institutions and Nonprofits only -
SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library E484K Tile 1 (positions 333-436)
Pooled Library#174293PurposeThis library contains mutations to SARS-CoV-2 Spike RBD E484K variant in which all surface exposed residues on S RBD (Tile 1, positions 333-436) were mutated to every other amino acid.DepositorExpressionYeastAvailable SinceSept. 13, 2021AvailabilityAcademic Institutions and Nonprofits only -
Liu Lab MusCK (A + B)
Pooled Library#1000000178DepositorAvailable SinceOct. 29, 2021AvailabilityAcademic Institutions and Nonprofits only -
LibTest
Pooled Library#113147PurposeCustomized sgRNA library targeting 86 E. coli genesDepositorExpressionBacterialAvailable SinceMay 14, 2019AvailabilityAcademic Institutions and Nonprofits only -
E.coli_GW-sgRNA_Lib5
Pooled Library#113138PurposeGenome-wide gRNA library for E. coli, sub5DepositorExpressionBacterialAvailable SinceMay 14, 2019AvailabilityAcademic Institutions and Nonprofits only -
Humagne Set C
Pooled Library#172650PurposeSet C contains best-ranked guides 1 and 4.DepositorExpressionMammalianAvailable SinceNov. 10, 2021AvailabilityAcademic Institutions and Nonprofits only -
PB-EF1a-Puro-V8.2
Pooled Library#178943PurposeBarcoding library for the macsGESTALT inducible lineage recording systemDepositorExpressionMammalianAvailable SinceMarch 22, 2022AvailabilityAcademic Institutions and Nonprofits only -
Humagne Set D
Pooled Library#172651PurposeSet D contains best-ranked guides 2 and 3.DepositorExpressionMammalianAvailable SinceNov. 10, 2021AvailabilityAcademic Institutions and Nonprofits only