We narrowed to 29 results for: tec

1. Large-scale mismatched sgRNA library for gene titration (human essential genes, CRISPRi)

   Pooled Library

   #136478

   Purpose

   Expresses gRNAs for gene titration of ~2400 human genes using CRISPRi

   Depositor

   Jonathan Weissman

   Article

   Jost et al Nat Biotechnol. 2020 Jan 13. pii: 10.103

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   Feb. 25, 2020

   Availability

   Academic Institutions and Nonprofits only

2. CHyMErA Exon-deletion hgRNA Library

   Pooled Library

   #155200

   Purpose

   Hybrid guide RNA library targeting human alternative cassette exons for deletion and disruption

   Depositor

   Benjamin Blencowe, Jason Moffat

   Article

   Gonatopoulos-Pournatzis et al Nat Biotechnol. 2020 May;38(5):638-648.

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   Sept. 2, 2020

   Availability

   Academic Institutions and Nonprofits only

3. CHyMErA Paralog&Dual-targeting hgRNA Library

   Pooled Library

   #155199

   Purpose

   Hybrid guide RNA library targetings human paralog pairs and other protein-coding genes.

   Depositor

   Benjamin Blencowe, Jason Moffat

   Article

   Gonatopoulos-Pournatzis et al Nat Biotechnol. 2020 May;38(5):638-648.

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   Sept. 2, 2020

   Availability

   Academic Institutions and Nonprofits only

4. Human Base Editing Sensor Library

   Pooled Library

   #179218

   Purpose

   sgRNAs that target frequently occurring cancer associated mutations identified in the MSK IMPACT dataset that can be modeled with cytosine base editing.

   Depositor

   Lukas Dow

   Article

   Sanchez-Rivera et al Nat Biotechnol. 2022 Feb 14. pii: 10.103

   Expression

   Mammalian

   Use

   Lentiviral

   Available since

   June 16, 2022

   Availability

   Academic Institutions and Nonprofits only

5. Mouse Base Editing Sensor Library

   Pooled Library

   #179217

   Purpose

   sgRNAs that target frequently occurring cancer associated mutations identified in the MSK IMPACT dataset that can be modeled with cytosine base editing.

   Depositor

   Lukas Dow

   Article

   Sanchez-Rivera et al Nat Biotechnol. 2022 Feb 14. pii: 10.103

   Expression

   Mammalian

   Use

   Lentiviral

   Available since

   June 16, 2022

   Availability

   Academic Institutions and Nonprofits only

6. ALL-PAM sensor Library

   Pooled Library

   #179219

   Purpose

   10 human and mouse sgRNAs each where for each sgRNA the tethered target site has 1 of 64 possible 3 bp PAM sequences.

   Depositor

   Lukas Dow

   Article

   Sanchez-Rivera et al Nat Biotechnol. 2022 Feb 14. pii: 10.103

   Expression

   Mammalian

   Use

   Lentiviral

   Available since

   June 16, 2022

   Availability

   Academic Institutions and Nonprofits only

7. Wei lab paired-guide RNA (pgRNA) CRISPR–Cas9 library for human long non-coding RNAs (lncRNAs)

   Pooled Library

   #89640

   Purpose

   Paired sgRNA library containing 12,472 pgRNAs targeting 671 human long non-coding RNAs (lncRNAs)

   Depositor

   Wensheng Wei

   Article

   Zhu et al Nat Biotechnol. 2016 Dec;34(12):1279-128

   Expression

   Mammalian

   Use

   Lentiviral

   Available since

   May 17, 2017

   Availability

   Academic Institutions and Nonprofits only

8. CROPseq-iT7 Human CRISPR Knockout Pooled Library (Brunello)

   Pooled Library

   #223064

   Purpose

   Optical pooled genome-scale CRISPR KO screening using Nuclear In-Situ Sequencing (NIS-Seq)

   Depositor

   Jonathan Schmid-Burgk

   Article

   Fandrey et al Nat Biotechnol. 2024 Dec 19. doi: 10.103

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   May 23, 2025

   Availability

   Academic Institutions and Nonprofits only

9. pMuSIC pool v1.0

   Pooled Library

   #227193

   Purpose

   Two-way barcodes from 18 fluorescent proteins for mammalian expression. Can be used for clone tracing, or for pairing with perturbations for single cell resolution in spectral detection measurements.

   Depositor

   Marc Birtwistle

   Article

   Lu et al bioRxiv [Preprint]. 2024 Oct 24:2024.10.

   Expression

   Mammalian

   Available since

   Dec. 18, 2024

   Availability

   Academic Institutions and Nonprofits only