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Showing: 41 - 60 of 135 results

  1. ACER

    Pooled library
    #226117
    Purpose
    Contains 748 traditional and newly predicted epigenetic regulators using epigenetic network analyses that integrated gene codependency (DepMap) and protein-protein interaction data (BioPlex).
    Depositor
    Rui Lu
    Publication
    Zhou et al Blood. 2024 Aug 16:blood.2023023644. doi
    Expression
    Mammalian
    Species
    Homo sapiens
    Use
    CRISPR and Lentiviral
    Available since
    Oct. 29, 2024
    Availability
    Academic Institutions and Nonprofits only

  2. Barcode Library 0 (BCL0)

    Pooled library
    #179851
    Purpose
    Lentiviral barcode library that consists of 10^6 unique barcodes. Barcodes consist of 12bp degenerate region followed by two stable bases (C or G) and 4bp unique library code ACGT.
    Depositor
    Jason Moffat
    Publication
    Rehman et al Cell. 2021 Jan 7;184(1):226-242.e21. doi
    Expression
    Mammalian
    Use
    Lentiviral
    Available since
    May 12, 2022
    Availability
    Academic Institutions and Nonprofits only

  9. SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library N501Y Tile 2 (positions 437-527)

    Pooled library
    #174296
    Purpose
    This library contains mutations to SARS-CoV-2 Spike RBD N501Y variant in which all surface exposed residues on S RBD (Tile 2, positions 437-527) were mutated to every other amino acid.
    Depositor
    Timothy Whitehead
    Publication
    Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:
    Expression
    Yeast
    Available since
    Sept. 13, 2021
    Availability
    Academic Institutions and Nonprofits only

  10. SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library N501Y Tile 1 (positions 333-436)

    Pooled library
    #174295
    Purpose
    This library contains mutations to SARS-CoV-2 Spike RBD N501Y variant in which all surface exposed residues on S RBD (Tile 1, positions 333-436) were mutated to every other amino acid.
    Depositor
    Timothy Whitehead
    Publication
    Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:
    Expression
    Yeast
    Available since
    Sept. 13, 2021
    Availability
    Academic Institutions and Nonprofits only

  11. SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library E484K Tile 2 (positions 437-527)

    Pooled library
    #174294
    Purpose
    This library contains mutations to SARS-CoV-2 Spike RBD E484K variant in which all surface exposed residues on S RBD (Tile 2, positions 437-527) were mutated to every other amino acid.
    Depositor
    Timothy Whitehead
    Publication
    Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:
    Expression
    Yeast
    Available since
    Sept. 13, 2021
    Availability
    Academic Institutions and Nonprofits only

  12. SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library E484K Tile 1 (positions 333-436)

    Pooled library
    #174293
    Purpose
    This library contains mutations to SARS-CoV-2 Spike RBD E484K variant in which all surface exposed residues on S RBD (Tile 1, positions 333-436) were mutated to every other amino acid.
    Depositor
    Timothy Whitehead
    Publication
    Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:
    Expression
    Yeast
    Available since
    Sept. 13, 2021
    Availability
    Academic Institutions and Nonprofits only

  13. Mouse Validation (mVAL) CRISPR Library

    Pooled library
    #159391
    Purpose
    Targets 182 immune evasion genes. Designed for loss-of-function screening against genes shown to increase sensistivity or resistance of cancer cells to cytotoxic T lymphocyte-mediated toxicity.
    Depositor
    Jason Moffat
    Publication
    Lawson et al Nature. 2020 Oct;586(7827):120-126. doi:
    Expression
    Mammalian
    Species
    Mus musculus
    Use
    CRISPR and Lentiviral
    Available since
    Nov. 9, 2020
    Availability
    Academic Institutions and Nonprofits only

  14. Julianna (split-vector)

    Pooled library
    #247028
    Purpose
    Enriched for effective guides through prioritization of guides with strong on-target activity. Designed against current gene annotations, offering coverage of the contemporary mouse genome.
    Depositor
    John Doench, David Root
    Publication
    Drepanos et al Cell Genom. 2026 May 13;6(5):101190. doi
    Has service
    Lentiviral Prep
    Expression
    Mammalian
    Species
    Mus musculus
    Use
    CRISPR and Lentiviral
    Available since
    Oct. 2, 2025
    Availability
    Academic Institutions and Nonprofits only

  17. BARBEKO sgRNA library

    Pooled library
    #174163
    Purpose
    Cytosine base editors for genome-scale knockout screens in human cells. Targets gene start codons, splice sites, or introduces premature termination codons.
    Depositor
    Wensheng Wei
    Publication
    Xu et al Nat Biotechnol. 2021 Jun 21. pii: 10.103
    Expression
    Mammalian
    Species
    Homo sapiens
    Use
    CRISPR and Lentiviral
    Available since
    Aug. 31, 2021
    Availability
    Academic Institutions and Nonprofits only

  18. pCVSN2c-MCP-oScarlet-KASH-6xMS2 Barcode Library

    Pooled library
    #227672
    Purpose
    RVdG genome plasmids that carry an error-correctable barcode compatible with 3’ capture single cell or single nuclei RNA sequencing readout. For the production of CVS N2c strain G-deleted rabies virus
    Depositor
    Cathryn Cadwell, Tomasz Nowakowski
    Publication
    Shin et al bioRxiv [Preprint]. 2024 Dec 11:2024.10.
    Expression
    Mammalian
    Species
    Synthetic
    Available since
    Feb. 12, 2025
    Availability
    Academic Institutions and Nonprofits only
Showing: 41 - 60 of 135 results