We narrowed to 125 results for: nes

1. TP53 MITE Library

   Pooled Library

   #113569

   Purpose

   Pooled lentiviral plasmid library containing ~8,000 single amino acid substitution and nonsense mutant variants of p53

   Depositor

   William Hahn, David Root

   Article

   Giacomelli et al Nat Genet. 2018 Oct;50(10):1381-1387. do

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   Lentiviral

   Available Since

   Jan. 4, 2019

   Availability

   Academic Institutions and Nonprofits only

2. CHyMErA LbCas12a Nuclease Optimization hgRNA Library

   Pooled Library

   #209734

   Purpose

   CHyMErA Cas12a Nuclease Optimization hgRNA Libraries allows assessment and comparison of the efficacy of different LbCas12a nucleases in the context of the Cas9-Cas12a CHyMErA system.

   Depositor

   Thomas Gonatopoulos-Pournatzis

   Article

   Xiao et al Mol Cell. 2024 Jul 11;84(13):2553-2572.e

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available Since

   June 20, 2024

   Availability

   Academic Institutions and Nonprofits only

3. CHyMErA AsCas12a Nuclease Optimization hgRNA Library

   Pooled Library

   #209735

   Purpose

   CHyMErA Cas12a Nuclease Optimization hgRNA Libraries allows assessment and comparison of the efficacy of different AsCas12a nucleases in the context of the Cas9-Cas12a CHyMErA system.

   Depositor

   Thomas Gonatopoulos-Pournatzis

   Article

   Xiao et al Mol Cell. 2024 Jul 11;84(13):2553-2572.e

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available Since

   June 20, 2024

   Availability

   Academic Institutions and Nonprofits only

4. HR700_TP53Exon5mut

   Pooled Library

   #229137

   Purpose

   Donor vector library to introduce TP53 mutations into the endogenous gene locus at exon 5 of human cells via CRISPR-HDR.

   Depositor

   Thorsten Stiewe

   Article

   Funk et al Nat Genet. 2025 Jan;57(1):140-153. doi:

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Cre/Lox

   Available Since

   Feb. 24, 2025

   Availability

   Industry, Academic Institutions, and Nonprofits

5. HR700_TP53Exon6mut

   Pooled Library

   #229138

   Purpose

   Donor vector library to introduce TP53 mutations into the endogenous gene locus at exon 6 of human cells via CRISPR-HDR.

   Depositor

   Thorsten Stiewe

   Article

   Funk et al Nat Genet. 2025 Jan;57(1):140-153. doi:

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Cre/Lox

   Available Since

   Feb. 24, 2025

   Availability

   Industry, Academic Institutions, and Nonprofits

6. HR700_TP53Exon7mut

   Pooled Library

   #229139

   Purpose

   Donor vector library to introduce TP53 mutations into the endogenous gene locus at exon 7 of human cells via CRISPR-HDR.

   Depositor

   Thorsten Stiewe

   Article

   Funk et al Nat Genet. 2025 Jan;57(1):140-153. doi:

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Cre/Lox

   Available Since

   Feb. 24, 2025

   Availability

   Industry, Academic Institutions, and Nonprofits

7. HR700_TP53Exon8mut

   Pooled Library

   #229140

   Purpose

   Donor vector library to introduce TP53 mutations into the endogenous gene locus at exon 8 of human cells via CRISPR-HDR.

   Depositor

   Thorsten Stiewe

   Article

   Funk et al Nat Genet. 2025 Jan;57(1):140-153. doi:

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Cre/Lox

   Available Since

   Feb. 24, 2025

   Availability

   Industry, Academic Institutions, and Nonprofits

8. Barcode Library 0 (BCL0)

   Pooled Library

   #179851

   Purpose

   Lentiviral barcode library that consists of 10^6 unique barcodes. Barcodes consist of 12bp degenerate region followed by two stable bases (C or G) and 4bp unique library code ACGT.

   Depositor

   Jason Moffat

   Article

   Rehman et al Cell. 2021 Jan 7;184(1):226-242.e21. doi

   Expression

   Mammalian

   Use

   Lentiviral

   Available Since

   May 12, 2022

   Availability

   Academic Institutions and Nonprofits only

9. Barcode Library 1 (BCL1)

   Pooled Library

   #179852

   Purpose

   Lentiviral barcode library that consists of 10^6 unique barcodes. Barcodes consist of 12bp degenerate region followed by two stable bases (C or G) and 4bp unique library code CCAA.

   Depositor

   Jason Moffat

   Article

   Rehman et al Cell. 2021 Jan 7;184(1):226-242.e21. doi

   Expression

   Mammalian

   Use

   Lentiviral

   Available Since

   May 12, 2022

   Availability

   Academic Institutions and Nonprofits only

10. Human SAM library in lentiSAMv2 backbone

    Pooled Library

    #1000000078

    Purpose

    Genome-wide CRISPR gRNA pooled library for activation of human genes

    Depositor

    Feng Zhang

    Available Since

    June 27, 2016

    Availability

    Academic Institutions and Nonprofits only

11. hCRISPRa-v2, genome-wide, 10 sgRNAs/gene

    Pooled Library

    #1000000091

    Purpose

    Genome-wide CRISPR gRNA pooled library for activation of human genes

    Depositor

    Jonathan Weissman

    Available Since

    Nov. 15, 2016

    Availability

    Academic Institutions and Nonprofits only

12. mCRISPRa-v2, genome-wide, 10 sgRNAs/gene

    Pooled Library

    #1000000093

    Purpose

    Genome-wide CRISPR gRNA pooled library for activation of mouse genes

    Depositor

    Jonathan Weissman

    Available Since

    Nov. 15, 2016

    Availability

    Academic Institutions and Nonprofits only

13. mCRISPRi-v2, genome-wide, 10 sgRNAs/gene

    Pooled Library

    #1000000092

    Purpose

    Genome-wide CRISPR gRNA pooled library for inhibition of mouse genes

    Depositor

    Jonathan Weissman

    Available Since

    Nov. 15, 2016

    Availability

    Academic Institutions and Nonprofits only

14. Human SAM library in lenti sgRNA(MS2)_puro backbone

    Pooled Library

    #1000000074

    Purpose

    Genome-wide CRISPR gRNA pooled library for activation of mouse genes

    Depositor

    Feng Zhang

    Available Since

    March 17, 2016

    Availability

    Academic Institutions and Nonprofits only

15. Human CRISPRi sgRNA library Dolcetto in backbone XPR_050

    Pooled Library

    #1000000114

    Purpose

    Genome-wide CRISPR gRNA pooled library for inhibition of human genes

    Depositor

    John Doench, David Root

    Available Since

    July 13, 2018

    Availability

    Academic Institutions and Nonprofits only

16. Mouse CRISPRi sgRNA library Dolomiti in backbone XPR_050

    Pooled Library

    #1000000131

    Purpose

    Genome-wide CRISPR gRNA pooled library for inhibition of mouse genes

    Depositor

    John Doench, David Root

    Available Since

    July 13, 2018

    Availability

    Academic Institutions and Nonprofits only

17. Human SAM Library in lenti sgRNA(MS2)_zeo backbone

    Pooled Library

    #1000000057

    Purpose

    Genome-wide CRISPR gRNA pooled library for activation of human genes

    Depositor

    Feng Zhang

    Available Since

    Jan. 16, 2015

    Availability

    Academic Institutions and Nonprofits only

18. Mouse SAM Library in lenti sgRNA(MS2)_puro optimized backbone

    Pooled Library

    #1000000075

    Purpose

    Genome-wide CRISPR gRNA pooled library for activation of mouse genes

    Depositor

    Feng Zhang

    Available Since

    March 17, 2016

    Availability

    Academic Institutions and Nonprofits only

19. Human CRISPRa sgRNA library Calabrese in backbone XPR_502 (P65 HSF)

    Pooled Library

    #1000000111

    Purpose

    Genome-wide CRISPR gRNA pooled library for activation of human genes

    Depositor

    John Doench, David Root

    Available Since

    Aug. 3, 2017

    Availability

    Academic Institutions and Nonprofits only

20. Mouse CRISPRa sgRNA library Caprano in backbone XPR_502 (P65 HSF)

    Pooled Library

    #1000000113

    Purpose

    Genome-wide CRISPR gRNA pooled library for activation of mouse genes

    Depositor

    John Doench, David Root

    Available Since

    July 13, 2018

    Availability

    Academic Institutions and Nonprofits only