We narrowed to 241 results for: Gene

1. BLaER1 pgRNA CRISPR library

   Pooled Library

   #183825

   Purpose

   CRISPR-Cas9 library to target lncRNAs and protein coding genes with a potential role in B-cell to macrophage transdifferentiation.

   Depositor

   Roderic Guigo

   Article

   Arnan et al BMC Genomics. 2022 May 26;23(1):402. doi

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available Since

   Aug. 25, 2022

   Availability

   Academic Institutions and Nonprofits only

2. Drosophila_sgRNA_group_1

   Pooled Library

   #134582

   Purpose

   Targets kinases, phosphatases, and Drosophila orthologs of drug targets

   Depositor

   Norbert Perrimon

   Article

   Viswanatha et al Elife. 2018 Jul 27;7. pii: 36333. doi: 1

   Expression

   Insect

   Species

   Drosophila melanogaster

   Use

   CRISPR

   Available Since

   Feb. 25, 2020

   Availability

   Academic Institutions and Nonprofits only

3. Human SAM library in lentiSAMv2 backbone

   Pooled Library

   #1000000078

   Purpose

   Genome-wide CRISPR gRNA pooled library for activation of human genes

   Depositor

   Feng Zhang

   Available Since

   June 27, 2016

   Availability

   Academic Institutions and Nonprofits only

4. DDR_MKOv4

   Pooled Library

   #140219

   Purpose

   CRISPR DNA damage response library

   Depositor

   Junjie Chen

   Article

   Su et al DNA Repair (Amst). 2020 Jan 16;87:102803

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available Since

   Aug. 20, 2021

   Availability

   Academic Institutions and Nonprofits only

5. Human CRISPRi sgRNA library Dolcetto in backbone XPR_050

   Pooled Library

   #1000000114

   Purpose

   Genome-wide CRISPR gRNA pooled library for inhibition of human genes

   Depositor

   David Root, John Doench

   Available Since

   July 13, 2018

   Availability

   Academic Institutions and Nonprofits only

6. Mouse CRISPRi sgRNA library Dolomiti in backbone XPR_050

   Pooled Library

   #1000000131

   Purpose

   Genome-wide CRISPR gRNA pooled library for inhibition of mouse genes

   Depositor

   David Root, John Doench

   Available Since

   July 13, 2018

   Availability

   Academic Institutions and Nonprofits only

7. Human SAM library in lenti sgRNA(MS2)_puro backbone

   Pooled Library

   #1000000074

   Purpose

   Genome-wide CRISPR gRNA pooled library for activation of mouse genes

   Depositor

   Feng Zhang

   Available Since

   March 17, 2016

   Availability

   Academic Institutions and Nonprofits only

8. Human SAM Library in lenti sgRNA(MS2)_zeo backbone

   Pooled Library

   #1000000057

   Purpose

   Genome-wide CRISPR gRNA pooled library for activation of human genes

   Depositor

   Feng Zhang

   Available Since

   Jan. 16, 2015

   Availability

   Academic Institutions and Nonprofits only

9. Mouse SAM Library in lenti sgRNA(MS2)_puro optimized backbone

   Pooled Library

   #1000000075

   Purpose

   Genome-wide CRISPR gRNA pooled library for activation of mouse genes

   Depositor

   Feng Zhang

   Available Since

   March 17, 2016

   Availability

   Academic Institutions and Nonprofits only

10. Human CRISPRa sgRNA library Calabrese in backbone XPR_502 (P65 HSF)

    Pooled Library

    #1000000111

    Purpose

    Genome-wide CRISPR gRNA pooled library for activation of human genes

    Depositor

    David Root, John Doench

    Available Since

    Aug. 3, 2017

    Availability

    Academic Institutions and Nonprofits only

11. Mouse CRISPRa sgRNA library Caprano in backbone XPR_502 (P65 HSF)

    Pooled Library

    #1000000113

    Purpose

    Genome-wide CRISPR gRNA pooled library for activation of mouse genes

    Depositor

    David Root, John Doench

    Available Since

    July 13, 2018

    Availability

    Academic Institutions and Nonprofits only

12. RLC12

    Pooled Library

    #163954

    Purpose

    RLC12 pooled library

    Depositor

    Jeremy Rock

    Article

    Bosch et al Cell. 2021 Jul 16. pii: S0092-8674(21)00

    Expression

    Bacterial

    Use

    CRISPR

    Available Since

    Oct. 1, 2021

    Availability

    Academic Institutions and Nonprofits only

13. Mouse Metabolism Library

    Pooled Library

    #163966

    Purpose

    Lentiviral CRISPR library targets 2,918 mouse metabolic genes with ~18,000 guide RNAs. The library contains ~6 gRNAs per gene.

    Depositor

    Alec Kimmelman

    Article

    Biancur et al Cell Metab. 2020 Oct 28. pii: S1550-4131

    Use

    CRISPR and Lentiviral

    Available Since

    July 1, 2021

    Availability

    Academic Institutions and Nonprofits only

14. RLC11

    Pooled Library

    #163955

    Purpose

    RLC11 pooled library

    Depositor

    Jeremy Rock

    Article

    Bosch et al Cell. 2021 Jul 16. pii: S0092-8674(21)00

    Expression

    Bacterial

    Use

    CRISPR

    Available Since

    Oct. 1, 2021

    Availability

    Academic Institutions and Nonprofits only

15. pSMAL-CellTag-multi-v1 barcode library

    Pooled Library

    #206045

    Purpose

    The CellTag multi library of barcodes can be used to clonally label cells with DNA barcodes. These barcodes can be profiled directly with single-cell RNA and ATAC sequencing, to allow clonal tracking

    Depositor

    Samantha Morris

    Article

    Jindal et al Nat Biotechnol. 2023 Sep 25. doi: 10.103

    Use

    Lentiviral

    Available Since

    Nov. 2, 2023

    Availability

    Academic Institutions and Nonprofits only

16. Oxford Drosophila melanogaster Genome-wide CRISPR Library

    Pooled Library

    #64750

    Purpose

    A genome-wide CRISPR library covering 13,501 genes (98.8% of the Drosophila melanogaster genome), among which 8,989 genes are targeted by three or more independent single guide RNAs (sgRNAs).

    Depositor

    Ji-Long Liu

    Article

    Bassett et al J Genet Genomics. 2015 Jun 20;42(6):301-

    Expression

    Insect

    Species

    Drosophila melanogaster, Streptococcus pyogenes, and Synthetic

    Use

    CRISPR

    Available Since

    March 7, 2016

    Availability

    Academic Institutions and Nonprofits only

17. The Human Druggable CRISPR library

    Pooled Library

    #200013

    Purpose

    The library contains ~10,000 sgRNAs targeting 1,980 human genes (5 sgRNAs per gene and 100 nontargeting control sgRNAs).

    Depositor

    Lianxin Liu

    Article

    Zheng et al Adv Sci (Weinh). 2023 Aug;10(22):e220679

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available Since

    May 9, 2023

    Availability

    Academic Institutions and Nonprofits only

18. Mouse lipid metabolism knockout library

    Pooled Library

    #206248

    Purpose

    The lipid metabolism library contains guide RNAs against 295 genes targeting mouse genes encoding enzymes that directly impact lipid metabolism.

    Depositor

    Kivanc Birsoy

    Article

    Soula et al Nature. 2024 Aug 7. doi: 10.1038/s41586-

    Use

    CRISPR and Lentiviral

    Available Since

    Aug. 29, 2024

    Availability

    Academic Institutions and Nonprofits only

19. Pan-Druggable Cancer Library

    Pooled Library

    #182133

    Purpose

    All-in-one CRISPR/Cas system with 74 individual elements. 63 elements target cancer-related genes with FDA-approved drug treatments, and 3 elements target key medulloblastoma driver genes.

    Depositor

    Prashant Mali

    Article

    Hu et al Biomaterials. 2022 Jan;280:121276. doi:

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available Since

    Aug. 26, 2022

    Availability

    Academic Institutions and Nonprofits only

20. Mouse Cardiac Transcriptional Regulators CRISPR Knockout Library

    Pooled Library

    #138015

    Purpose

    This library can be used to investigate cardiac gene regulation. It targets transcriptional regulators that are expressed in mouse cardiomyocytes. A subset of GATA4 regulated genes are also included.

    Depositor

    William Pu

    Article

    VanDusen et al bioRxiv 2019, 808402v1; doi: https://doi

    Species

    Mus musculus

    Use

    AAV, CRISPR, and Cre/Lox

    Available Since

    April 17, 2020

    Availability

    Academic Institutions and Nonprofits only