We narrowed to 251 results for: Gene

#247027

Human genome-wide CRISPR knockout library for the use of S. pyogenes Cas9. Each gene is targeted by 3 constructs.

John Doench, David Root

Drepanos et al bioRxiv 2025.08.26.672375; doi: https://

Oct. 2, 2025

Academic Institutions and Nonprofits only

#247026

Human genome-wide CRISPR knockout library for the use of S. pyogenes Cas9. Each gene is targeted by 3 constructs.

John Doench, David Root

Drepanos et al bioRxiv 2025.08.26.672375; doi: https://

Oct. 2, 2025

Academic Institutions and Nonprofits only

#163966

Knockout library targeting mouse metabolic genes.

Alec Kimmelman

Biancur et al Cell Metab. 2020 Oct 28. pii: S1550-4131

July 1, 2021

Academic Institutions and Nonprofits only

#247028

Enriched for effective guides through prioritization of guides with strong on-target activity. Designed against current gene annotations, offering coverage of the contemporary mouse genome.

John Doench, David Root

Drepanos et al bioRxiv 2025.08.26.672375; doi: https://

Oct. 2, 2025

Academic Institutions and Nonprofits only

#168791

Knockout library targeting human mRNA binding proteins with 10 sgRNAs/gene.

Martin Turner

Turner et al CRISPR J. 2021 Jun;4(3):427-437. doi: 10

July 30, 2021

Academic Institutions and Nonprofits only

#170432

Concise library targeting the whole genome of S. pneumoniae D39V with one sgRNA per operon or gene.

Jan-Willem Veening

Liu et al Cell Host Microbe. 2021 Jan 13;29(1):107

Aug. 31, 2021

Academic Institutions and Nonprofits only

#182133

Knockout library targeting cancer-related genes.

Prashant Mali

Hu et al Biomaterials. 2022 Jan;280:121276. doi:

Aug. 26, 2022

Academic Institutions and Nonprofits only

#123361

CRISPR-Cpf1/Cas12a double knockout library. Targets 26 genes, chosen from analysis of human metastasis cohorts. It can be used to interrogate the genetic interactions driving metastasis.

Sidi Chen

Chow et al Nat Methods. 2019 May;16(5):405-408. doi

June 10, 2019

Academic Institutions and Nonprofits only

#64750

Library designed for genomic targeting and screening in Drosophila cells. All possible gRNA target sites within the shared exonic regions on either DNA strand of the Drosophila genome were computed.

Ji-Long Liu

Bassett et al J Genet Genomics. 2015 Jun 20;42(6):301-

March 7, 2016

Academic Institutions and Nonprofits only

#136986

Designed for assays with limited cell numbers with 2 guides per gene. Compatible with John Doench’s Brunello human genome-wide library.

John Doench

DeWeirdt et al Nat Commun. 2020 Feb 6;11(1):752. doi: 1

Feb. 24, 2020

Academic Institutions and Nonprofits only

#177663

CRISPR-interference (CRISPRi) library of 1,573 sgRNAs targeting 476 genes encoding factors involved in DNA repair and associated processes

Brittany Adamson

Hussmann et al Cell. 2021 Oct 28;184(22):5653-5669.e25.

July 11, 2023

Academic Institutions and Nonprofits only

#136987

Designed for assays with limited cell numbers with 2 guides per gene. Compatible with John Doench’s Brie mouse genome-wide library.

John Doench

DeWeirdt et al Nat Commun. 2020 Feb 6;11(1):752. doi: 1

Feb. 24, 2020

Academic Institutions and Nonprofits only

#206249

The sphingolipid metabolism library targets 82 mouse genes in the de novo ceramide and downstream sphingolipid metabolism pathways.

Kivanc Birsoy

Soula et al Nature. 2024 Aug 7. doi: 10.1038/s41586-

Aug. 29, 2024

Academic Institutions and Nonprofits only

#164084

Knockout library targeting human genes required for mTORC1 activation and inhibition.

David Sabatini

Condon et al Proc Natl Acad Sci U S A. 2021 Jan 26;11

Jan. 11, 2021

Academic Institutions and Nonprofits only

#113585

AAV-CRISPR library for pool mutagenesis of top tumor suppressor genes in mouse liver

Sidi Chen

Wang et al Sci Adv. 2018 Feb 28;4(2):eaao5508. doi:

July 23, 2019

Academic Institutions and Nonprofits only

#113584

AAV-CRISPR library for pool mutagenesis of top tumor suppressor genes

Sidi Chen

Wang et al Sci Adv. 2018 Feb 28;4(2):eaao5508. doi:

July 23, 2019

Academic Institutions and Nonprofits only

#190744

Targets proximal poly(A) signal sequences in genes identified to be differentially polyadenylated in the mouse B16-F10 melanoma system.

Robert Bradley

Gabel et al Nat Commun. 2024 Feb 1;15(1):959. doi: 1

Feb. 2, 2024

Academic Institutions and Nonprofits only

#177664

CRISPR-interference (CRISPRi) library of 366 sgRNAs targeting 118 genes encoding factors involved in DNA repair and associated processes

Brittany Adamson

Hussmann et al Cell. 2021 Oct 28;184(22):5653-5669.e25.

Nov. 29, 2023

Academic Institutions and Nonprofits only

#226117

Contains 748 traditional and newly predicted epigenetic regulators using epigenetic network analyses that integrated gene codependency (DepMap) and protein-protein interaction data (BioPlex).

Rui Lu

Zhou et al Blood. 2024 Aug 16:blood.2023023644. doi

Oct. 29, 2024

Academic Institutions and Nonprofits only

#229137

Donor vector library to introduce TP53 mutations into the endogenous gene locus at exon 5 of human cells via CRISPR-HDR.

Thorsten Stiewe

Funk et al Nat Genet. 2025 Jan;57(1):140-153. doi:

Feb. 24, 2025

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