We narrowed to 241 results for: Gene

1. mU6-CR1-CRISPRiv2_hU6-CR3-NT-ctrl-guide_EF1a-PuroR-T2A-BFP

   Pooled Library

   #197348

   Purpose

   To allow for genome-wide genetic modifier screening, the library has a second fixed non-targeting control guide.

   Depositor

   Jonathan Weissman, Rebecca Voorhees

   Article

   Guna et al BMC Genomics. 2023 Oct 30;24(1):651. doi

   Species

   Homo sapiens

   Use

   Lentiviral

   Available Since

   May 25, 2023

   Availability

   Academic Institutions and Nonprofits only

2. mU6-CR1-CRISPRiv2_hU6-CR3-EMC2-guide_EF1a-PuroR-T2A-BFP

   Pooled Library

   #197349

   Purpose

   To allow for genome-wide genetic modifier screening, the library has a second fixed guide targeting EMC2.

   Depositor

   Jonathan Weissman, Rebecca Voorhees

   Article

   Guna et al BMC Genomics. 2023 Oct 30;24(1):651. doi

   Species

   Homo sapiens

   Use

   Lentiviral

   Available Since

   May 25, 2023

   Availability

   Academic Institutions and Nonprofits only

3. Human SLC SAM Library

   Pooled Library

   #132561

   Purpose

   Expresses gRNAs for activation of human Solute Carrier family genes

   Depositor

   Giulio Superti-Furga

   Article

   Rebsamen et al Life Sci Alliance. 2022 Sep 16;5(11):e20

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available Since

   May 18, 2020

   Availability

   Academic Institutions and Nonprofits only

4. Human sgRNA library Brunello in lentiCRISPRv2

   Pooled Library

   #73179

   Purpose

   Human sgRNA library in backbone lentiCRISPRv2 targeting 19,114 genes and containing 76,441 unique sgRNAs along with 1000 non-targeting controls

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Has Service

   Lentiviral Prep

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available Since

   Feb. 9, 2016

   Availability

   Academic Institutions and Nonprofits only

5. Human sgRNA library Brunello in lentiGuide-Puro

   Pooled Library

   #73178

   Purpose

   Human sgRNA library in backbone lentiGuide-Puro targeting 19,114 genes and containing 76,441 unique sgRNAs along with 1000 non-targeting controls

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Has Service

   Lentiviral Prep

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available Since

   Feb. 9, 2016

   Availability

   Academic Institutions and Nonprofits only

6. Mouse sgRNA library Brie in lentiCRISPRv2

   Pooled Library

   #73632

   Purpose

   Mouse sgRNA library in backbone lentiCRISPRv2 containing 78,637 unique sgRNAs targeting 19,674 genes along with 1000 non-targeting controls

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available Since

   Feb. 25, 2016

   Availability

   Academic Institutions and Nonprofits only

7. Mouse sgRNA library Brie in lentiGuide-Puro

   Pooled Library

   #73633

   Purpose

   Mouse sgRNA library in backbone lentiGuide-Puro containing 78,637 unique sgRNAs targeting 19,674 genes along with 1000 non-targeting controls

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Has Service

   Lentiviral Prep

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available Since

   Feb. 25, 2016

   Availability

   Academic Institutions and Nonprofits only

8. Human Lipid Droplet and Metabolism Library

   Pooled Library

   #191535

   Purpose

   Lentiviral CRISPR library targeting 1,196 genes related to lipid droplet biology and cell metabolism.

   Depositor

   James Olzmann

   Article

   Roberts et al Dev Cell. 2023 Jul 18:S1534-5807(23)0033

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available Since

   March 1, 2023

   Availability

   Academic Institutions and Nonprofits only

9. Mouse metabolism knockout library

   Pooled Library

   #160129

   Purpose

   CRISPR library targets mouse metabolic genes

   Depositor

   Kivanc Birsoy

   Article

   Zhu et al Cell Metab. 2020 Oct 28. pii: S1550-4131

   Expression

   Mammalian

   Species

   Mus musculus

   Use

   CRISPR and Lentiviral

   Available Since

   Nov. 10, 2020

   Availability

   Academic Institutions and Nonprofits only

10. Mouse Brie kinome pooled library, guides 1-4 in lentiGuide-Puro backbone

    Pooled Library

    #75316

    Purpose

    Mouse sgRNA library in backbone lentiGuide-Puro targeting 713 kinase genes and containing 2,852 unique sgRNAs along with 100 non-targeting controls

    Depositor

    David Root, John Doench

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Available Since

    June 27, 2016

    Availability

    Academic Institutions and Nonprofits only

11. Mouse Brie kinome pooled library, guides 1-4 in lentiCRISPRv2 backbone

    Pooled Library

    #75317

    Purpose

    Mouse sgRNA library in backbone lentiCRISPRv2 targeting 713 kinase genes and containing 2,852 unique sgRNAs along with 100 non-targeting controls

    Depositor

    David Root, John Doench

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Available Since

    June 27, 2016

    Availability

    Academic Institutions and Nonprofits only

12. Human Brunello kinome pooled library, guides 1-4 in lentiCRISPRv2 backbone

    Pooled Library

    #75314

    Purpose

    Human sgRNA library in backbone lentiCRISPRv2 targeting 763 kinase genes and containing 3,052 unique sgRNAs along with 100 non-targeting controls

    Depositor

    David Root, John Doench

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available Since

    June 27, 2016

    Availability

    Academic Institutions and Nonprofits only

13. DNA repair library with 1,513 sgRNAs

    Pooled Library

    #177670

    Purpose

    CRISPR-interference (CRISPRi) library designed to target 476 genes involved in DNA repair and associated processes. It contains 1,513 sgRNAs and 60 non-targeting control sgRNAs.

    Depositor

    Brittany Adamson

    Article

    Chen et al Cell. 2021 Oct 28;184(22):5635-5652.e29.

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available Since

    July 11, 2023

    Availability

    Academic Institutions and Nonprofits only

14. Human Brunello kinome pooled library, guides 5-8 in lentiCRISPRv2 backbone

    Pooled Library

    #75315

    Purpose

    Human sgRNA library in backbone lentiCRISPRv2 targeting 763 kinase genes and containing 3,052 unique sgRNAs along with 100 non-targeting controls

    Depositor

    David Root, John Doench

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available Since

    June 27, 2016

    Availability

    Academic Institutions and Nonprofits only

15. Pooled sgRNA Libraries Set 1 for Pseudomonas aeruginosa PA14

    Pooled Library

    #234855

    Purpose

    A CRISPRi library for inducible, genome-wide gene repression in Pseudomonas aeruginosa PA14.

    Depositor

    Xue Liu

    Article

    Zhang et al Nat Commun. 2025 Jul 1;16(1):5870. doi:

    Expression

    Bacterial

    Available Since

    June 5, 2025

    Availability

    Academic Institutions and Nonprofits only

16. CHyMErA Paralog&Dual-targeting hgRNA Library

    Pooled Library

    #155199

    Purpose

    Hybrid guide RNA library targetings human paralog pairs and other protein-coding genes.

    Depositor

    Benjamin Blencowe, Jason Moffat

    Article

    Gonatopoulos-Pournatzis et al Nat Biotechnol. 2020 May;38(5):638-648.

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available Since

    Sept. 2, 2020

    Availability

    Academic Institutions and Nonprofits only

17. Humagne Set C

    Pooled Library

    #172650

    Purpose

    Set C contains best-ranked guides 1 and 4.

    Depositor

    David Root, John Doench

    Article

    DeWeirdt et al Nat Biotechnol. 2020 Jul 13. pii: 10.103

    Expression

    Mammalian

    Available Since

    Nov. 10, 2021

    Availability

    Academic Institutions and Nonprofits only

18. Humagne Set D

    Pooled Library

    #172651

    Purpose

    Set D contains best-ranked guides 2 and 3.

    Depositor

    David Root, John Doench

    Article

    DeWeirdt et al Nat Biotechnol. 2020 Jul 13. pii: 10.103

    Expression

    Mammalian

    Available Since

    Nov. 10, 2021

    Availability

    Academic Institutions and Nonprofits only

19. sgRNA pool for Streptococcus pneumoniae

    Pooled Library

    #170432

    Purpose

    CRISPR library targeting S. pneumoniae D39V

    Depositor

    Jan-Willem Veening

    Article

    Liu et al Cell Host Microbe. 2021 Jan 13;29(1):107

    Expression

    Bacterial

    Use

    CRISPR

    Available Since

    Aug. 31, 2021

    Availability

    Academic Institutions and Nonprofits only

20. Mouse Chromatin Regulator Library

    Pooled Library

    #200011

    Purpose

    CRISPR KO library targeting a comprehensive set of genes with annotated function as chromatin regulators.

    Depositor

    Robert Manguso, Gabriel Griffin, Bradley Bernstein

    Article

    Griffin et al Nature. 2021 Jul;595(7866):309-314. doi:

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available Since

    Dec. 15, 2023

    Availability

    Academic Institutions and Nonprofits only