We narrowed to 8 results for: HA

1. CHyMErA Exon-deletion hgRNA Library

   Pooled Library

   #155200

   Purpose

   Hybrid guide RNA library targeting human alternative cassette exons for deletion and disruption

   Depositor

   Jason Moffat, Benjamin Blencowe

   Article

   Gonatopoulos-Pournatzis et al Nat Biotechnol. 2020 May;38(5):638-648.

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   Sept. 2, 2020

   Availability

   Academic Institutions and Nonprofits only

2. CHyMErA Paralog&Dual-targeting hgRNA Library

   Pooled Library

   #155199

   Purpose

   Hybrid guide RNA library targetings human paralog pairs and other protein-coding genes.

   Depositor

   Jason Moffat, Benjamin Blencowe

   Article

   Gonatopoulos-Pournatzis et al Nat Biotechnol. 2020 May;38(5):638-648.

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   Sept. 2, 2020

   Availability

   Academic Institutions and Nonprofits only

3. mU6-CR1-CRISPRiv2_hU6-CR3-EMC2-guide_EF1a-PuroR-T2A-BFP

   Pooled Library

   #197349

   Purpose

   To allow for genome-wide genetic modifier screening, the library has a second fixed guide targeting EMC2.

   Depositor

   Jonathan Weissman, Rebecca Voorhees

   Article

   Guna et al BMC Genomics. 2023 Oct 30;24(1):651. doi

   Species

   Homo sapiens

   Use

   Lentiviral

   Available since

   May 25, 2023

   Availability

   Academic Institutions and Nonprofits only

4. mU6-CR1-CRISPRiv2_hU6-CR3-NT-ctrl-guide_EF1a-PuroR-T2A-BFP

   Pooled Library

   #197348

   Purpose

   To allow for genome-wide genetic modifier screening, the library has a second fixed non-targeting control guide.

   Depositor

   Jonathan Weissman, Rebecca Voorhees

   Article

   Guna et al BMC Genomics. 2023 Oct 30;24(1):651. doi

   Species

   Homo sapiens

   Use

   Lentiviral

   Available since

   May 25, 2023

   Availability

   Academic Institutions and Nonprofits only

5. ALL-PAM sensor Library

   Pooled Library

   #179219

   Purpose

   10 human and mouse sgRNAs each where for each sgRNA the tethered target site has 1 of 64 possible 3 bp PAM sequences.

   Depositor

   Lukas Dow

   Article

   Sanchez-Rivera et al Nat Biotechnol. 2022 Feb 14. pii: 10.103

   Expression

   Mammalian

   Use

   Lentiviral

   Available since

   June 16, 2022

   Availability

   Academic Institutions and Nonprofits only

6. plIG-123_HA-GD2-28z_CAR_TF_Library

   Pooled Library

   #207478

   Purpose

   HA-GD2-28z CAR in combination with 100 transcription factors (and related proteins) and 2 controls (GFP/RFP). Library can be used to generate HDR templates for modular pooled knockin (ModPoKI) into th

   Depositor

   Alexander Marson

   Article

   Blaeschke et al Cell. 2023 Sep 14;186(19):4216-4234.e33.

   Species

   Homo sapiens

   Use

   CRISPR

   Available since

   Jan. 26, 2024

   Availability

   Academic Institutions and Nonprofits only

7. plIG-128_HA-GD2-28z_CAR_TFxTF_Library

   Pooled Library

   #207480

   Purpose

   HA-GD2-28z CAR in combination with ~10,000 transcription factor combinations (and related proteins) and controls (GFP/RFP combinations). Library can be used to generate HDR templates for modular poole

   Depositor

   Alexander Marson

   Article

   Blaeschke et al Cell. 2023 Sep 14;186(19):4216-4234.e33.

   Use

   CRISPR

   Available since

   Jan. 26, 2024

   Availability

   Academic Institutions and Nonprofits only

8. plIG-124_HA-GD2-28z_CAR_SR_Library

   Pooled Library

   #207479

   Purpose

   HA-GD2-28z CAR in combination with 129 surface receptors and 2 controls (GFP/RFP). Library can be used to generate HDR templates for modular pooled knockin (ModPoKI) into the TRAC locus of human T cel

   Depositor

   Alexander Marson

   Article

   Blaeschke et al Cell. 2023 Sep 14;186(19):4216-4234.e33.

   Species

   Homo sapiens

   Use

   CRISPR

   Available since

   Jan. 26, 2024

   Availability

   Academic Institutions and Nonprofits only