963 results

1. pAAV-CaMKIIa-HA-hM4D(Gi)-IRES-mCitrine (AAV8)

   Viral Prep

   #50467-AAV8

   Purpose

   Ready-to-use AAV8 particles produced from pAAV-CaMKIIa-HA-hM4D(Gi)-IRES-mCitrine (#50467). In addition to the viral particles, you will also receive purified pAAV-CaMKIIa-HA-hM4D(Gi)-IRES-mCitrine plasmid DNA. CaMKIIa-driven HA-tagged hM4D(Gi) and bicistronic mCitrine expression, for chemogenetic inhibition. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Bryan Roth

   Promoter

   CaMKII

   Tags

   mCitrine

   Available since

   May 29, 2020

   Availability

   Academic Institutions and Nonprofits only

2. pAAV-nEF-Con/Foff 2.0-iC++-EYFP (AAV8)

   Viral Prep

   #137156-AAV8

   Purpose

   Ready-to-use AAV8 particles produced from pAAV-nEF-Con/Foff 2.0-iC++-EYFP (#137156). In addition to the viral particles, you will also receive purified pAAV-nEF-Con/Foff 2.0-iC++-EYFP plasmid DNA. nEF-driven, Cre-dependent expression of chloride-conducting channelrhodopsin iC++-EYFP (inhibited in presence of Flp) for optogenetic inhibition. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Karl Deisseroth, INTRSECT 2.0 Project

   Article

   Fenno et al Neuron. 2020 Jun 20. pii: S0896-6273(20)

   Promoter

   nEF

   Tags

   EYFP (Cre-dependent)

   Available since

   Nov. 25, 2020

   Availability

   Academic Institutions and Nonprofits only

3. pGP-AAV-CAG-FLEX-jGCaMP7s-WPRE (AAV1)

   Viral Prep

   #104495-AAV1

   Purpose

   Ready-to-use AAV1 particles produced from pGP-AAV-CAG-FLEX-jGCaMP7s-WPRE (#104495). In addition to the viral particles, you will also receive purified pGP-AAV-CAG-FLEX-jGCaMP7s-WPRE plasmid DNA. CAG-driven, Cre-dependent GCaMP7s calcium sensor. These AAV preparations are suitable purity for injection into animals.

   Depositor

   GENIE Project, Douglas Kim

   Article

   Dana et al Nat Methods. 2019 Jul;16(7):649-657. doi

   Promoter

   CAG

   Tags

   None

   Available since

   Aug. 24, 2020

   Availability

   Academic Institutions and Nonprofits only

4. pAAV-CAG-eYFP (AAV PHP.eB)

   Viral Prep

   #104055-PHPeB

   Purpose

   Ready-to-use AAV PHP.eB particles produced from pAAV-CAG-eYFP (#104055). In addition to the viral particles, you will also receive purified pAAV-CAG-eYFP plasmid DNA. CAG-driven eYFP expression control. These AAV were produced with the PHPeB serotype, which permits efficient transduction of the central nervous system. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Viviana Gradinaru

   Article

   Challis et al Nat Protoc. 2019 Feb;14(2):379-414. doi:

   Promoter

   CAG

   Tags

   EYFP

   Available since

   June 13, 2023

   Availability

   Academic Institutions and Nonprofits only

5. pENN.AAV.EF1a.eGFP.WPRE.rBG (AAV Retrograde)

   Viral Prep

   #105547-AAVrg

   Purpose

   Ready-to-use AAV Retrograde particles produced from pENN.AAV.EF1a.eGFP.WPRE.rBG (#105547). In addition to the viral particles, you will also receive purified pENN.AAV.EF1a.eGFP.WPRE.rBG plasmid DNA. EF1a-driven EGFP expression. These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.

   Depositor

   James M. Wilson

   Promoter

   EF1a

   Tags

   EGFP

   Available since

   Oct. 18, 2021

   Availability

   Academic Institutions and Nonprofits only

6. pZac2.1-GfaABC1D-lck-jGCaMP8f (AAV9)

   Viral Prep

   #176759-AAV9

   Purpose

   Ready-to-use AAV9 particles produced from pZac2.1-GfaABC1D-lck-jGCaMP8f (#176759). In addition to the viral particles, you will also receive purified pZac2.1-GfaABC1D-lck-jGCaMP8f plasmid DNA. GfaABC1D-driven expression of membrane-bound calcium sensor GCaMP8f. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Loren Looger

   Promoter

   GfaABC1D

   Tags

   None

   Available since

   Feb. 24, 2023

   Availability

   Academic Institutions and Nonprofits only

7. AAV-mDlx-jGCaMP8f-WPRE (AAV9)

   Viral Prep

   #176753-AAV9

   Purpose

   Ready-to-use AAV9 particles produced from AAV-mDlx-jGCaMP8f-WPRE (#176753). In addition to the viral particles, you will also receive purified AAV-mDlx-jGCaMP8f-WPRE plasmid DNA. mDlx enhancer-driven expression of calcium sensor GCaMP8f in GABA-ergic interneurons. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Loren Looger

   Promoter

   mDlx

   Tags

   None

   Available since

   Feb. 24, 2023

   Availability

   Academic Institutions and Nonprofits only

8. pGP-AAV-CAG-FLEX-jGCaMP7s-WPRE (AAV PHP.eB)

   Viral Prep

   #104495-PHPeB

   Purpose

   Ready-to-use AAV PHP.eB particles produced from pGP-AAV-CAG-FLEX-jGCaMP7s-WPRE (#104495). In addition to the viral particles, you will also receive purified pGP-AAV-CAG-FLEX-jGCaMP7s-WPRE plasmid DNA. CAG-driven, Cre-dependent GCaMP7s calcium sensor. These AAV were produced with the PHPeB serotype, which permits efficient transduction of the central nervous system. These AAV preparations are suitable purity for injection into animals.

   Depositor

   GENIE Project, Douglas Kim

   Article

   Dana et al Nat Methods. 2019 Jul;16(7):649-657. doi

   Promoter

   CAG

   Tags

   None

   Available since

   Feb. 5, 2024

   Availability

   Academic Institutions and Nonprofits only

9. pAAV-Ef1a-Con/Foff 2.0-mCherry (AAV8)

   Viral Prep

   #137133-AAV8

   Purpose

   Ready-to-use AAV8 particles produced from pAAV-Ef1a-Con/Foff 2.0-mCherry (#137133). In addition to the viral particles, you will also receive purified pAAV-Ef1a-Con/Foff 2.0-mCherry plasmid DNA. EF1a-driven, Cre-dependent expression of mCherry (inhibited in presence of Flp). These AAV preparations are suitable purity for injection into animals.

   Depositor

   Karl Deisseroth, INTRSECT 2.0 Project

   Article

   Fenno et al Neuron. 2020 Jun 20. pii: S0896-6273(20)

   Promoter

   EF1a

   Tags

   mCherry (Cre-dependent)

   Available since

   April 5, 2021

   Availability

   Academic Institutions and Nonprofits only

10. pAAV-CAG-Flex-mRuby2-GSG-P2A-GCaMP6s-WPRE-pA (AAV1)

    Viral Prep

    #68717-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV-CAG-Flex-mRuby2-GSG-P2A-GCaMP6s-WPRE-pA (#68717). In addition to the viral particles, you will also receive purified pAAV-CAG-Flex-mRuby2-GSG-P2A-GCaMP6s-WPRE-pA plasmid DNA. CAG-driven, Cre dependent, GCaMP6s calcium sensor and bicistronic, physically separate mRuby2 expression. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Tobias Rose, Mark Huebener, Tobias Bonhoeffer

    Article

    Rose et al Science. 2016 Jun 10;352(6291):1319-22.

    Promoter

    CAG-FLEX

    Tags

    mRuby2 (Cre-dependent)

    Available since

    May 4, 2018

    Availability

    Academic Institutions and Nonprofits only

11. pAAV-S5E2-Gq-P2A-dTomato (AAV1)

    Viral Prep

    #135635-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV-S5E2-Gq-P2A-dTomato (#135635). In addition to the viral particles, you will also receive purified pAAV-S5E2-Gq-P2A-dTomato plasmid DNA. Expression of Gq-DREADD and dTomato (physically separate) under the control of the E2 regulatory element. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Jordane Dimidschstein

    Article

    Vormstein-Schneider et al Nat Neurosci. 2020 Dec;23(12):1629-1636.

    Promoter

    Tags

    dTomato (physically separate, not a fusion protein)

    Available since

    Nov. 29, 2021

    Availability

    Academic Institutions and Nonprofits only

12. pAAV-Ef1a-Con/Foff 2.0-EYFP (AAV8)

    Viral Prep

    #137162-AAV8

    Purpose

    Ready-to-use AAV8 particles produced from pAAV-Ef1a-Con/Foff 2.0-EYFP (#137162). In addition to the viral particles, you will also receive purified pAAV-Ef1a-Con/Foff 2.0-EYFP plasmid DNA. EF1a-driven expression of EYFP in the presence of Cre (inhibited in the presence of Flp). These AAV preparations are suitable purity for injection into animals.

    Depositor

    Karl Deisseroth, INTRSECT 2.0 Project

    Article

    Fenno et al Neuron. 2020 Jun 20. pii: S0896-6273(20)

    Promoter

    EF1a

    Tags

    EYFP (Cre-dependent)

    Available since

    Feb. 2, 2021

    Availability

    Academic Institutions and Nonprofits only

13. pAAV-Ef1a-fDIO-ChrimsonR-tdTomato (AAV1)

    Viral Prep

    #171027-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV-Ef1a-fDIO-ChrimsonR-tdTomato (#171027). In addition to the viral particles, you will also receive purified pAAV-Ef1a-fDIO-ChrimsonR-tdTomato plasmid DNA. Flp-dependent, Ef1a-driven expression of ChrimsonR-tdTomato fusion for optogenetic activation. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Patricia Jensen

    Article

    Sciolino et al Sci Adv. 2022 Aug 19;8(33):eabn9134. doi

    Promoter

    EF1a

    Tags

    tdTomato

    Available since

    July 21, 2023

    Availability

    Academic Institutions and Nonprofits only

14. pAAV-S5E2-C1V1-eYFP (AAV9)

    Viral Prep

    #135633-AAV9

    Purpose

    Ready-to-use AAV9 particles produced from pAAV-S5E2-C1V1-eYFP (#135633). In addition to the viral particles, you will also receive purified pAAV-S5E2-C1V1-eYFP plasmid DNA. Expression of red-shifted opsin C1V1 fused to EYFP under the control of the E2 regulatory element. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Jordane Dimidschstein

    Article

    Vormstein-Schneider et al Nat Neurosci. 2020 Dec;23(12):1629-1636.

    Promoter

    Tags

    EYFP

    Available since

    Aug. 27, 2021

    Availability

    Academic Institutions and Nonprofits only

15. pGP-AAV-syn-FLEX-jGCaMP7s-WPRE (AAV Retrograde)

    Viral Prep

    #104491-AAVrg

    Purpose

    Ready-to-use AAV Retrograde particles produced from pGP-AAV-syn-FLEX-jGCaMP7s-WPRE (#104491). In addition to the viral particles, you will also receive purified pGP-AAV-syn-FLEX-jGCaMP7s-WPRE plasmid DNA. Synapsin-driven, Cre-dependent, GCaMP7s calcium sensor. These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.

    Depositor

    GENIE Project, Douglas Kim

    Article

    Dana et al Nat Methods. 2019 Jul;16(7):649-657. doi

    Promoter

    Syn

    Tags

    None

    Available since

    June 14, 2018

    Availability

    Academic Institutions and Nonprofits only

16. pAAV.GFA104.PI.eGFP.WPRE.bGH (AAV5)

    Viral Prep

    #100896-AAV5

    Purpose

    Ready-to-use AAV5 particles produced from pAAV.GFA104.PI.eGFP.WPRE.bGH (#100896). In addition to the viral particles, you will also receive purified pAAV.GFA104.PI.eGFP.WPRE.bGH plasmid DNA. GFA104-driven eGFP expression. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Philip Haydon

    Article

    Ortinski et al Nat Neurosci. 2010 May;13(5):584-91. doi

    Promoter

    GFA104 (GFAP promoter)

    Tags

    EGFP

    Available since

    April 6, 2018

    Availability

    Academic Institutions and Nonprofits only

17. pGP-AAV-CAG-FLEX-jGCaMP7s-WPRE (AAV Retrograde)

    Viral Prep

    #104495-AAVrg

    Purpose

    Ready-to-use AAV Retrograde particles produced from pGP-AAV-CAG-FLEX-jGCaMP7s-WPRE (#104495). In addition to the viral particles, you will also receive purified pGP-AAV-CAG-FLEX-jGCaMP7s-WPRE plasmid DNA. CAG-driven, Cre-dependent GCaMP7s calcium sensor. These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.

    Depositor

    GENIE Project, Douglas Kim

    Article

    Dana et al Nat Methods. 2019 Jul;16(7):649-657. doi

    Promoter

    CAG

    Tags

    None

    Available since

    Oct. 3, 2019

    Availability

    Academic Institutions and Nonprofits only

18. pAAV-Ef1a-mCherry (AAV9)

    Viral Prep

    #114470-AAV9

    Purpose

    Ready-to-use AAV9 particles produced from pAAV-Ef1a-mCherry (#114470). In addition to the viral particles, you will also receive purified pAAV-Ef1a-mCherry plasmid DNA. EF1a-driven mCherry expression. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Karl Deisseroth

    Promoter

    EF1a

    Tags

    mCherry

    Available since

    Jan. 6, 2022

    Availability

    Academic Institutions and Nonprofits only

19. pTR-UF11 (AAV.A01.T)

    Viral Prep

    #157970-AAV.A01.T

    Purpose

    Ready-to-use AAV2 in TMN200 particles produced from pTR-UF11 (#157970). In addition to the viral particles, you will also receive purified pTR-UF11 plasmid DNA. 'Humanized' GFP driven by Chimeric CMV/Chicken Beta Actin promoter

    Depositor

    Sergei Zolotukhin

    Article

    Burger et al Mol Ther. 2004 Aug;10(2):302-17. doi: 10

    Promoter

    chimeric CMV/Chicken Beta actin (CBA)

    Tags

    GFP

    Available since

    Dec. 21, 2020

    Availability

    Academic Institutions and Nonprofits only

20. pAAV_hsyn_NES-his-CaMPARI2-F391W-WPRE-SV40 (AAV1)

    Viral Prep

    #101061-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV_hsyn_NES-his-CaMPARI2-F391W-WPRE-SV40 (#101061). In addition to the viral particles, you will also receive purified pAAV_hsyn_NES-his-CaMPARI2-F391W-WPRE-SV40 plasmid DNA. Synapsin-driven, photoconvertible (irreversible green-to-red) calcium integrator his-tagged CaMPARI2-F391W. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Eric Schreiter

    Article

    Moeyaert et al Nat Commun. 2018 Oct 25;9(1):4440. doi:

    Promoter

    Syn

    Tags

    None

    Available since

    July 23, 2018

    Availability

    Academic Institutions and Nonprofits only