1,051 results

1. pAAV.CAG.iAChSnFR (AAV1)

   Viral Prep

   #137955-AAV1

   Purpose

   Ready-to-use AAV1 particles produced from pAAV.CAG.iAChSnFR (#137955). In addition to the viral particles, you will also receive purified pAAV.CAG.iAChSnFR plasmid DNA. CAG-driven iAChSnFR acetylcholine sensor. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Loren Looger

   Article

   Borden et al bioRxiv 2020

   Promoter

   CAG

   Available Since

   Oct. 28, 2021

   Availability

   Academic Institutions and Nonprofits only

2. pOTTC1032 - pAAV EF1a Nuc-flox(mCherry)-EGFP (AAV8)

   Viral Prep

   #112677-AAV8

   Purpose

   Ready-to-use AAV8 particles produced from pOTTC1032 - pAAV EF1a Nuc-flox(mCherry)-EGFP (#112677). In addition to the viral particles, you will also receive purified pOTTC1032 - pAAV EF1a Nuc-flox(mCherry)-EGFP plasmid DNA. EF1a-driven, Cre-dependent color switch. This AAV directs expression of nuclear mCherry in the absence of Cre. In the presence of Cre, nuclear EGFP (and not mCherry) will be expressed. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Brandon Harvey

   Article

   Back et al Neuron. 2019 Feb 8. pii: S0896-6273(19)3

   Promoter

   EF1a

   Tags

   mCherry (Cre-negative cells), EGFP (Cre-positive cells)

   Available Since

   Sept. 8, 2020

   Availability

   Academic Institutions and Nonprofits only

3. pAAV-CaMKIIa-hChR2(E123A)-EYFP (AAV9)

   Viral Prep

   #35505-AAV9

   Purpose

   Ready-to-use AAV9 particles produced from pAAV-CaMKIIa-hChR2(E123A)-EYFP (#35505). In addition to the viral particles, you will also receive purified pAAV-CaMKIIa-hChR2(E123A)-EYFP plasmid DNA. CaMKIIa-driven hChR2(E123A)-EYFP expression for optogenetic activation. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Karl Deisseroth

   Article

   Mattis et al Nat Methods. 2011 Dec 18;9(2):159-72. do

   Promoter

   CaMKII

   Tags

   EYFP

   Available Since

   May 24, 2018

   Availability

   Academic Institutions and Nonprofits only

4. pGP-AAV-CAG-FLEX-jGCaMP7f-WPRE (AAV PHP.eB)

   Viral Prep

   #104496-PHPeB

   Purpose

   Ready-to-use AAV PHP.eB particles produced from pGP-AAV-CAG-FLEX-jGCaMP7f-WPRE (#104496). In addition to the viral particles, you will also receive purified pGP-AAV-CAG-FLEX-jGCaMP7f-WPRE plasmid DNA. CAG-driven, Cre-dependent jGCaMP7f calcium sensor. These AAV were produced with the PHPeB serotype, which permits efficient transduction of the central nervous system. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Douglas Kim, GENIE Project

   Article

   Dana et al Nat Methods. 2019 Jul;16(7):649-657. doi

   Promoter

   CAG

   Available Since

   Sept. 27, 2023

   Availability

   Academic Institutions and Nonprofits only

5. pAAV-nEF-Con/Fon-ChR2(ET/TC)-EYFP (AAV8)

   Viral Prep

   #137139-AAV8

   Purpose

   Ready-to-use AAV8 particles produced from pAAV-nEF-Con/Fon-ChR2(ET/TC)-EYFP (#137139). In addition to the viral particles, you will also receive purified pAAV-nEF-Con/Fon-ChR2(ET/TC)-EYFP plasmid DNA. nEF-driven, Cre and Flp-dependent expression of ChR2(E123T/T159C)-EYFP for optogenetic activation. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Karl Deisseroth, INTRSECT 2.0 Project

   Article

   Fenno et al Neuron. 2020 Jun 20. pii: S0896-6273(20)

   Promoter

   nEF

   Tags

   EYFP (Cre and Flp-dependent)

   Available Since

   May 19, 2021

   Availability

   Academic Institutions and Nonprofits only

6. pAAV.hSynapsin.SF-iGluSnFR.S72A (AAV1)

   Viral Prep

   #106176-AAV1

   Purpose

   Ready-to-use AAV1 particles produced from pAAV.hSynapsin.SF-iGluSnFR.S72A (#106176). In addition to the viral particles, you will also receive purified pAAV.hSynapsin.SF-iGluSnFR.S72A plasmid DNA. hSynapsin driven SF-iGluSnFR.S72A, glutamate sensor. The S72A mutant has lower affinity for glutamate. Slower on-rate and faster off-rate. Enhanced temporal resolution and spatial resolution. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Loren Looger

   Article

   Marvin et al Nat Methods. 2018 Nov;15(11):936-939. do

   Promoter

   Syn

   Available Since

   Feb. 25, 2019

   Availability

   Academic Institutions and Nonprofits only

7. pAAV-hSyn1-Flex-mRuby2-GSG-P2A-GCaMP6s-WPRE-pA (AAV1)

   Viral Prep

   #68720-AAV1

   Purpose

   Ready-to-use AAV1 particles produced from pAAV-hSyn1-Flex-mRuby2-GSG-P2A-GCaMP6s-WPRE-pA (#68720). In addition to the viral particles, you will also receive purified pAAV-hSyn1-Flex-mRuby2-GSG-P2A-GCaMP6s-WPRE-pA plasmid DNA. Cre-dependent GCaMP6s calcium sensor and bicistronic, physically separate mRuby2 expression under a human synapsin1 promoter. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Mark Huebener, Tobias Rose, Tobias Bonhoeffer

   Article

   Rose et al Science. 2016 Jun 10;352(6291):1319-22.

   Promoter

   hSyn1-FLEX

   Tags

   mRuby2 (Cre-dependent)

   Available Since

   March 7, 2018

   Availability

   Academic Institutions and Nonprofits only

8. pOTTC1484 - pAAV SYN1 HA-hM4D(Gi) (AAV2)

   Viral Prep

   #121538-AAV2

   Purpose

   Ready-to-use AAV2 particles produced from pOTTC1484 - pAAV SYN1 HA-hM4D(Gi) (#121538). In addition to the viral particles, you will also receive purified pOTTC1484 - pAAV SYN1 HA-hM4D(Gi) plasmid DNA. Synapsin-driven, HA-tagged hM4D(Gi) for neuronal inhibition. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Christopher Richie

   Article

   Galvan et al Eur J Neurosci. 2019 May 7. doi: 10.1111

   Promoter

   Syn

   Tags

   HA

   Available Since

   Sept. 25, 2019

   Availability

   Academic Institutions and Nonprofits only

9. pAAV-CAG-dLight1.2 (AAV1)

   Viral Prep

   #111069-AAV1

   Purpose

   Ready-to-use AAV1 particles produced from pAAV-CAG-dLight1.2 (#111069). In addition to the viral particles, you will also receive purified pAAV-CAG-dLight1.2 plasmid DNA. CAG-driven expression of dLight1.2 dopamine sensor. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Lin Tian

   Article

   Patriarchi et al Science. 2018 Jun 29;360(6396). pii: sci

   Available Since

   Feb. 14, 2022

   Availability

   Academic Institutions and Nonprofits only

10. pZac2.1-GfaABC1D-lck-jGCaMP8m (AAV1)

    Viral Prep

    #176760-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pZac2.1-GfaABC1D-lck-jGCaMP8m (#176760). In addition to the viral particles, you will also receive purified pZac2.1-GfaABC1D-lck-jGCaMP8m plasmid DNA. GfaABC1D-driven expression of membrane-bound calcium sensor GCaMP8m. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Loren Looger

    Promoter

    GfaABC1D

    Available Since

    Feb. 24, 2023

    Availability

    Academic Institutions and Nonprofits only