New Viral Vectors - Summer 2024
Type
Blog Post
...viral service with multiple serotypes
pAAV-hSyn-GRAB_OTmut
AAV9
Biosensors (Control)
Li
New viral service...
We narrowed to 402 results for: Mut
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What's New in CRISPR - May 2019
TypeBlog Post.... Thus, they engineered two CBE variants with mutations in the rat APOBEC1 that decreases the number of... -
What's New in CRISPR - Spring 2019
TypeBlog Post...DNA strand. The lab then found gain-of-function mutations that allows it to be repurposed for double strand... -
CRISPR-Cas14: a family of small DNA-targeting enzymes enabling high-fidelity SNP genotyping
TypeBlog Post...infectious organisms (ex: SARS-CoV-2) and genetic mutations. By providing a gRNA specific of a viral sequences... -
Fluorescent Proteins 101: History of Fluorescent Proteins
TypeBlog Post... protein’s structure and also discovered many mutations that alter and improve its function and shift ... -
What's New in CRISPR - December 2019
TypeBlog Post...Single base editor that induces C-to-T and A-to-G mutations Nozomu Yachie’s lab recently developed a base ... -
Modulate the Activity of 17 Signaling Pathways with One Kit!
TypeBlog Post...pathways, they identified a set of one to three mutant complementary DNAs (cDNAs) representing core nodes... -
Six Spooky Science Stories and Halloween at Addgene
TypeBlog Post...discovered in Drosophila melanogaster (Gilbert, 2004). Mutations in these genes are lethal, associated with defective... -
What's New in CRISPR - September 2019
TypeBlog Post...activation and genome editing by fusing Cas9 to a mutated human estrogen receptor. This protein fusion stays... -
New Norepinephrine Indicators: nLightG and nLightR
TypeBlog Post...adrenergic receptor; nLightG contains circularly permuted green fluorescent protein (GFP), and nLightR uses... -
Working 9-5: an Addgene Co-op
TypeBlog Post...useful to me as some days it was not as easy to commute as others. I know some fear that remote work would... -
6 Steps to Submitting a Resume That Gets Seen
TypeBlog Post...manager on paper or as an email send directly from a mutual connection. If the organization is small, any person... -
Plasmids 101: Walkthrough of Addgene’s Snapgene-Powered Quality Control Process
TypeBlog Post...confirm the identity of the gene and check for any mutations. Once we identify the gene, we can easily annotate... -
Build Your CRISPR Vocabulary
TypeBlog Post...other hand, viruses can evolve to evade CRISPR by mutating these sequences. Pro tip! Various labs have created... -
Hot Plasmids - October 2022
TypeBlog Post...high-throughput screening platform to apply saturating mutagenesis on 21 positions in the protein sequence of the... -
Plasmids 101: Gene, enhancer, and promoter trapping
TypeBlog Post...to generate a collection of monitored genes and mutants - viral integration, transposon, and many more!... -
Hot Plasmids and Viral Preps - July 2021
TypeBlog Post...control and a SL-sensitive fluorophore (circularly permuted green fluorescent protein or cpGFP) to the petunia... -
Chemogenetics vs. Optogenetics: Which Method Should I Choose?
TypeBlog Post... The opsin ChETA, for example, is a ChR2 opsin mutated to have faster off kinetics and allow neurons to... -
Sleeping Beauty Awakens for Genome Engineering
TypeBlog Post... exciting tool for producing specific genetic mutations and gene disruptions without the use of viral ... -
History of CRISPR Cas - A tale of survival and evolution
TypeBlog Post...CRISPR/Cas defense by generating a single point mutation in the PAM sequence, preventing the Cas nucleases...