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We narrowed to 497 results for: RAP

Showing: 281 - 300 of 497 results

  6. CRISPR 101: Cytosine and Adenine Base Editors

    Type
    Blog Post
    ...T cells, making them a promising tool for cell therapy applications. Dual base editors What about combining...adenine base editors with increased activity and therapeutic application. Nature Biotechnology, 38(7), 892...

  7. Adeno-associated virus (AAV) Guide

    Type
    Guide
    ...ideal for gene therapy, neuroscience research, and other biomedical fields. Gene Therapy One of the major...AAV) as novel vectors for human gene therapy . Current Gene Therapy, 3 (4), 281–304. https://doi.org/10.2174...serotypes: vector toolkit for human gene therapy . Molecular Therapy, 14 (3), 316–327. https://doi.org/10.1016...preferred choice to be used as viral vectors for gene therapy applications. This guide contains many viral vector-specific...applications of rAAV vectors is in the field of gene therapy to treat genetic disorders. rAAV vectors are favored...insertional mutagenesis. Several AAV-based gene therapies have been approved by the US Food and Drug Administration...dystrophy. Many clinical trials of AAV-based gene therapies are underway and are promising for the treatment...

  8. Lentiviral Vector Guide

    Type
    Guide
    ...order to facilitate immunotherapy and gene therapy. Biomedicine & Pharmacotherapy , 128 , 110276. https...predict. In therapeutic applications, like chimeric antigen receptor T cell (CAR-T) therapy, the location...delivery of gene therapies. Lentiviral vectors are particularly effective for stem cell therapies, which rely...are common in clinical applications, like gene therapy, as you can more specifically dictate the target...oncogenes and other disease-associated genes. Gene Therapy Due to their relative safety and ability to transduce...transduce by other means. A concern with gene therapies is the possibility of transducing healthy tissues... of nonspecific transduction, lentiviral gene therapies have been shown to be relatively safe and effective...

  9. Adenovirus Guide

    Type
    Guide
    ...platforms within the gene therapy landscape . Signal Transduction and Targeted Therapy, 6 (1), 53. https://...The immune system recognizes adenoviral elements rapidly and can mount a strong immune response quickly,...quickly, which has limited their use in therapeutic applications. However, this has also made them the most ...disadvantage for the use of rAdV vectors in gene therapy but has, however, proven to be very useful for ...adenoviral vectors are also being used in cancer therapy to stimulate anti-tumor immune response in different...implications and circumvention strategies . Current Gene Therapy, 11 (4), 307–320. https://doi.org/10.2174/156652311796150372...for outbreak pathogens . Human Vaccines & Immunotherapeutics, 13 (12), 3020–3032. https://doi.org/10.1080...

  10. We’re Going Viral This Week!

    Type
    Blog Post
    ... we’ll cover a different topic as shown in the graphic below. Follow the hashtag #AddgeneGoesViral to ...

  12. Gamma-Retroviral Vector Guide

    Type
    Guide
    ...used in gene therapy applications to more specifically direct delivery of gene therapies. Common Uses ...gamma-retroviral vectors. Gene Therapy Gamma-retroviral vectors are a popular choice in gene therapy applications. There...There are many approved gamma-retroviral gene therapies to treat disease like cancer or immunodeficiency...Delivery of chimeric antigen receptor T cell (CAR-T) therapy is a particularly popular application of gamma-...and provide stable integration of the intended therapeutic. While similar to lentiviral vectors, they offer...centrifugation for CAR T cell manufacturing. Molecular Therapy — Methods & Clinical Development , 28 , 116–128...

  14. Trimmer Lab NeuroMab Collection

    Type
    Collection
    ...opens in a new window) Crosnier C, et al. 2010. A rapid and scalable method for selecting recombinant mouse...

  15. Deck the Lab 2022!

    Type
    Blog Post
    ... pic.twitter.com/rExV3b8Q8u— Michael Früh (@Michelderapfel) December 19, 2022   Congratulations to all...
Showing: 281 - 300 of 497 results