We narrowed to 680 results for: RON
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TypeBlog Post...virtue of liberating data from paper into an electronic environment and hence making it searchable and shareable...founder of Research Space. There are many types of electronic lab notebooks (ELNs), each with its own pros ... of Research Space, which provides the RSpace electronic lab notebook. Rory is based in Cambridge, Massachusetts...on the Addgene blog Find tips on choosing an electronic lab notebook Watch a livestream of the Minisymposium...
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Rett Syndrome: A History of Research and Therapeutic Outlooks
TypeBlog Post...CpG dinucleotides and CAC trinucleotides during neuronal maturation (Tillotson & Bird, 2019) and is a global...of symptoms in animal models, Rett syndrome is a strong translational candidate for gene replacement therapy...therapy. In 2014, RSRT brought together a strong collaboration between two gene therapy labs (Brian Kaspar... half of the mutant MECP2 RNA in each of three neuronal subtypes of the hippocampus. This technology has...Modifications in Human-Induced Pluripotent Stem Cells. Front Genet 10: . https://doi.org/10.3389/fgene.2019.00625... -
An Integrin Antibody Toolkit from IPI
TypeBlog Post... and the linkage of intra- and extracellular environments. Found on nearly every cell in the human body...membrane, physically connecting the extracellular environment and the cytoskeleton. Most integrins have three...responses to mechanical forces in the cell’s microenvironment. The actin cytoskeleton exerts tensile force... by the ligand embedded in the extracellular environment. This further stabilizes the extended open integrin...integrin inhibitors and natural ligands, such as fibronectin, to block receptor function, e.g., cell adhesion... -
March for Science
TypeBlog Post...aspects of research at National Aeronautics and Space Agency, the Environmental Protection Agency, and the ...Additionally, interest groups are often pandered to when strong or overlooked when small, but data is not going...Science face deep cuts in Trump’s first budget Environmental Science and Technology: Crossing The Imaginary...having evidence’ on Trump’s wiretap claim The Chronicle of Higher Education: “March for Science” Organizer... -
Transferable Skills Guide: Conflict Resolution
TypeBlog Post...reviewer’s concerns, you are making your hypothesis stronger. When you share data at a conference poster session.... It can be extremely toxic in a lab or work environment if left unchecked. Substantive conflict occurs...handy: Empathy: If you often find yourself in confrontational situations with others because you simply cannot...Empathizing with people, especially people with whom you strongly disagree, is a critical component of conflict ...will be considered in the right, and one in the wrong. If you arbitrate, one party might get exactly what... -
Thoughts on the Future of Research 2015 Boston Symposium
TypeBlog Post... increase diversity in the academic research environment. The “how many?” question lies at the base of... fact that training in the academic research environment is setup to prepare trainees for further work...receive as postdocs is not transferrable to other environments. Slide from Paula Stephan’s Talk (All slides...succeed in publishing in the current academic environment. Some great tips from this panel included: ... the structural problems within the research environment itself. At Addgene we hope that all parties involved... -
Building Global Connections with the International Mentorship Program USA-EUROPE
TypeBlog Post... the midst of a rapidly changing, globalized environment re-emerging from international financial struggle...but also nurture a supportive and protective environment where individuals are empowered to productively...opportunities that truly exist outside their immediate frontiers. Moreover, sharing a culture/country of origin...work? IMP Pilot Program 2015-2015 Scholars need strong proactive mentors who have relevant expertise and...and entrepreneurial visions thereby opening new frontiers for young talent around the world. The wealth ... -
A Guide to Getting Started in Undergrad Research
TypeBlog Post...climate change to study plant and marine biology, environmental microbiology, or biofuel production. There’s...Research requires dedication and effort, so building a strong understanding of what you’re getting yourself into...all just people. I’ve found that in the right environment and with supportive mentors, being open and vulnerable... what I don’t know yet has helped me cultivate stronger relationships with my labmates. Sometimes what...the vital things to look for is a supportive environment—it makes all the difference in a lab experience... -
Let There Be LITE Plasmids
TypeBlog Post...now available in Addgene’s repository for use in neurons, both in culture and in living brain tissue. “The...explained. “It helps us adapt to influences in our environments. We are able to react and learn. All of this... the LITEs to control gene expression in mouse neurons and in the brains of living mice both quickly and... want to apply LITEs for the transformation of neurons, she offers a tip: save yourself some time by making... -
What's New in CRISPR - December 2019
TypeBlog Post...fluorescent tags in neurons. Their toolkit named ORANGE (Open Resource for the Application of Neuronal Genome Editing...CRISPR/Cas9-based toolkit for epitope tagging in neurons Harold MacGillavry’s lab developed a CRISPR-based...targeted genomic integration of fluorescent tags in neurons. Read the paper in bioRxiv Find the ORANGE toolkit...