...writer at the non-profit Fred Hutchinson Cancer Research Center. Susan Keown’s science communication journey...Eye Institute (NEI), where she wrote about NEI research for a general audience. She then got a full time...it.” Science writing at Fred Hutchinson Cancer Research Center Work as a Science Writer at the Hutch ...meetings and Susan is assigned to cover the Clinical Research Division at Fred Hutch, so she attends that division...writing: plain-language stories about Fred Hutch research, pieces for donors such as fundraising materials...did for the Northwest Association of Biomedical Research. She does, however, recommend using Twitter as...

...your own company, work in a bench research career or a non-bench research career such as law, medical/technical...nonprofit entity, or nonprofit research organizations or governmental research organizations. Since there ...Law has seen that research institutions are willing to sponsor postdoctoral researchers for the EB-1B using...part of career development for foreign national researchers and entrepreneurs who are looking to continue...first 3 quarters of 2017. As an international researcher and aspiring entrepreneur, you have many career...complete your Ph.D. or postdoc. Foreign national researchers who require visas, permanent residence or citizenship...aligned with their education/experience, i.e. a research role, for a Ph.D. trained scientist. If the candidate...

...plasmid pET21a-BirA.   DNA / protein database search and analysis tools Addgene's analyze sequence ...

...different labs and experimental systems in their own research. Cyanobacteria, a phylum of photosynthetic bacteria...

...with Seeding Labs to provide plasmid grants to researchers in developing countries. Today we’re proud to... to use plasmids from Addgene to advance their research. Louis Bengyella Dr. Bengyella’s work has focused... As previously, these awards will be open to researchers who have received equipment through Seeding Labs... Addgene Blog Learn about Plasmid Awards to Researchers Working on Rare Diseases Read About Some of Our... search...

...Researchers in developing countries often find themselves on the front lines of emerging global challenges...challenges. However, these same researchers face significant barriers to scientific discovery and career ... see it as part of our mission to enable all researchers and are proud to announce that we are teaming...opportunities and scientific resources available to researchers in developing countries--because scientific talent...supply surplus lab equipment to carefully-screened research and teaching departments at universities around...working with Seeding Labs to award plasmids to research labs that have received Instrumental Access equipment... these plasmids will effectively advance their research. The map below shows all the countries that have...

...further contribute to our mission to “accelerate research and discovery.” Here are the details. Plasmids...include 10 plasmids that can be directly used in the research on the SARS-CoV-2. Nine of the overall plasmid...

... team identified Archon1, a novel opsin-based fluorescent voltage indicator. Archon1 can embed itself ...compatible with optogenetic control. The researchers also showed that Archon1 is functional in a wide range of...activity using the fluorescent voltage indicator Archon Article contributed by Shreya Vedantam  Listen ...membrane where cell voltage can then be measured. Archon1 is  bright, exhibits good localization, has high...models such as mice, C.elegans, and Zebrafish. Find Archon1 plasmids at Addgene! Piatkevich KD et al, Nat Chem...

...inhibition of action potential generation. Archaerhodopsin (Arch) is activated at a similar spectrum as HR...through hydrogen ion efflux; evidence suggests that Arch may more effectively silence neurons than HR. Delivering... the first time in the history of neuroscience research we have a technology that allows us to show causality...discarded but clearly we are in an era of neuroscience research where optogenetics will be a standard tool used...the National Institutes of Drug Abuse Intramural Research Program (NIH-NIDA IRP), with the stated goal of...they can be used is to consult the many primary research papers that have been published at this point....construct using stereotaxic surgery is a neuroscience research technique often used beyond just optogenetics....

...actuator. In 2012, Adam Cohen's lab presented Archaerhodopsin 3 (Arch) as a new rhodopsin based voltage indicator...potentials. The Cohen lab wished to improve on the Arch indicator and their collaborators in Robert Campbell...five rounds of random mutagenesis on a library of Arch mutants screening for improved brightness. The brightest...indicators: QuasAr1 and QuasAr2 (quality superior to Arch). Both QuasAr1 and QuasAr2 possess mutations for... electrodes. The Cohen lab has made the original Arch indicator (pJMK004), as well as the CheRiff, QuasAr...domain. Feng Zhang's group utilized the bi-lobed architecture of Cas9 to engineer a series of "split" cas9...Chao, Robert Singer, and Anne Ephrussi allows researchers to observe when and where translation occurs ...

...these constructs available at Addgene. These include Arch(D95N) and QuasAr, as well as the eFRET sensors, ...systems for mammalian screens, which enables researchers to maximize the chance of transducing a only ...downstream of the apoB gene. Using this reporter, the researchers explore many aspects of ApoB-LP biology, including...

...concentration gradient, and of activation inhibitory (ArCH) proton pump passing ions against the concentration...blue light-activated cation channel, from the archaebacteria Chlamydomonas reinhardtii. When exposed to ...combination with retinal) variations designed to give researchers flexibility in using optogenetic tools in their...proteins activate their signaling pathways allowing researchers greater control over when and where to activate...

...Kralj Voltage Voltage sensors for use in C. elegans (Arch(D95N), MacQ-mCitrine, QuasAr and QuasAr-mOrange)...Lin Voltage Fluorescent voltage reporters Archon 1 and Archon 2 (Constitutive or Cre-dependent) A robotic...extracellular vs. organelle-localized). Browse or search the tables below highlighting a few popular categories...Genetically Encoded Calcium Indicators. Janelia Research Campus. Online resource. 2020 GENIE Project Calcium...Nat Methods. 2023 Sep;20(9):1426-1436. Tommaso Patriarchi Norepinephrine GRAB_NE family of GPCR activation-based... Nat Methods. 2022 Feb;19(2):231-241. Tommaso Patriarchi Serotonin Red and green serotonin sensors GRAB...expression constructs? Browse the table below or search for a biosensor by name, target, publication title...

...Methanogenic archaeon Bacterial Ahmed Badran 209739 pAB228i24 G1 PylRS Methanogenic archaeon Bacterial Ahmed...implementing, or troubleshooting GCE experiments in your research, you can get advice from GCE experts by subscribing...service was set up in 2022 by the NIH-funded GCE4All Research Center . Browse Synthetase Plasmids The table ...Elsaesser 154763 pAS_FLAG-G1 PylRS G1 PylRS M. archaeon Mammalian TAG Simon Elsaesser 154764 pAS_FLAG-...154768 pAS_4xG1 PylT FLAG-G1 PylRS G1 PylRS M. archaeon Mammalian TAG Simon Elsaesser 154769 pAS_4xG1 ...4xG1 PylT FLAG-G1 PylRS Y125A G1 PylRS Y125A M. archaeon Mammalian TAG Simon Elsaesser 154773 pAS_4xhybPylT...A41AA C55A FLAG-G1 PylRS Y125A G1 PylRS Y125A M. archaeon Mammalian TAG Simon Elsaesser 154774 pAS_4xU6-...

...protein mutations. Research Articles : A list of free access articles on COVID-19 research. Protocols : Protocols...can be found here: ASM COVID-19 Research Registry COVID-19 Open Research Dataset (CORD-19) LitCovid (NCBI...plasmids and resources available for Coronavirus research. Collections...and Coronavirus Plasmids & Resources The global research community is moving quickly to expand the knowledge...available that may be useful for COVID-19 related research. Additionally, we have linked to collections of...Protocols that may be useful for COVID-19 research. Antibodies Anti-SARS-CoV-2 Nucleocapsid Protein [mBG17...available as soon as possible. For a full list of searchable plasmids, see the table below. SARS-CoV-2 Viral...

...different types of viruses that are commonly used in research, and to find plasmids that can be used to engineer...engineer viruses for a wide array of research purposes. Ready-to-use viral preparations for select plasmids...virus-mediated delivery has many advantages for research. Viruses facilitate the delivery of genetic information... (left). B) Viral plasmids can be modified for research purposes such that, when delivered to a host, ...but instead encode for a specific gene or other research interest. To produce viruses with alternate (non-virus-producing...giving rise to more virus (as happens in nature), researchers can introduce plasmids to a host to generate ...harbor a wide array of viral genomes, enabling researchers to direct a wide array of genetic functions in...

...window) encourages researchers to assemble and share tools for Parkinson's Disease research. This collection...Neurodegeneration Research Collection , which includes other areas of this research topic. Michael J. ...Shared Research Tools Labs affiliated with MJFF have also generated a number of Shared Research Tools ... Disease Plasmid Resource MJFF Plasmids Shared Research Tools (Link opens in a new window) The Michael...SNCA , and other proteins of interest. Browse or search the table below. ID Plasmid Gene/Insert Mutations...editing tools deposited with Addgene. Browse or search the table below. ID Plasmid Description Gene/Insert...

...Broswe plasmids and other research tools for use in Rett Syndrome research....The (Link opens in a new window) Rett Syndrome Research Trust (RSRT) was launched in 2008 to drive the...Rett Syndrome plasmid resource for the scientific research community. Background Rett Syndrome Rett syndrome...account for almost 46% of all Rett syndrome cases. Research Milestones 1992 - MECP2 is discovered by Adrian...syndrome and restore functional MECP2 in cells. Search (Link opens in a new window) JAX Mice for mouse...plasmids, please see Addgene's Plasmids for Stem Cell Research page. CRISPR Tools CRISPR technology is a promising... that express or target the MECP2 gene. Use the search bar or sort buttons to find plasmids based on: ...

...mutant clones for your course-based undergraduate research experience (CURE) projects....Collection Blog post: Course-Based Undergraduate Research Experiences (CUREs) (Link opens in a new window...develops protein-centric Course-based Undergraduate Research Experiences (CUREs) centered on a single enzyme...national group of educational leaders providing research opportunities to their students and other members...educators interested in integrating MDH-related research into their teaching laboratories. They encourage...and mutants provides a shared experience for the research community and facilitates scientific collaborations...available to download from each plasmid page. Use the search bar or sort buttons to find plasmids based on: ...

...AAV5 pAAV-CAG-FLEX-Archon1-KGC-EGFP-ER2 AAV production plasmid encoding for Archon1 fluorescent voltage...Li 115892-AAV8 pAAV-Syn-Archon1-KGC-GFP-ER2 AAV-mediated expression of Archon1-KGC-GFP-ER2 under the Syn...AAV8 pAAV-Syn-FLEX-rc [Archon1-KGC-GFP-ER2] AAV-mediated expression of Archon1-KGC-GFP-ER2 under the Syn...development of biomolecular tools for neuroscience research. Browse the BRAIN Initiative collection of plasmids...Initiative BRAIN Initiative Collection The Brain Research through Advancing Innovative Neurotechnologies...and circuits during behavior. Long desired by researchers, the revolutionary dynamic picture of the brain...emphasizes their rapid and broad dissemination to the research community. Browse plasmids , viral preps , and...