We narrowed to 955 results for: ARC;
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TypeCollection...) Zhang Pooled Barcoding Libraries ID Name Description PI 115643 Morris CellTag Barcode Library Version... the CellTag barcoding library. Version 1 of the Celltag library contains 19973 barcodes to combinatorially...of the CellTag barcoding library. Version 2 of the Celltag library contains 4934 barcodes to combinatorially...of the CellTag barcoding library. Version 3 of the Celltag library contains 5737 barcodes to combinatorially...Lentivirus Pooled CRISPR Libraries Cas9 Pooled Barcoding Libraries Control Addgene's lentiviruses are made...direct fluorescence. Morris 115644 Morris CellTag Barcode Library Version 2 Ready-to-use lentiviral particles...direct fluorescence. Morris 115645 Morris CellTag Barcode Library Version 3 Ready-to-use lentiviral particles...
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Penn Vector Core Partnership with Addgene
TypeCollection...-AAV1 AAV-FLEX-Arch-GFP Optogenetics Ed Boyden AV-1-PV2527 99039-AAV1 pAAV-CamKII-ArchT-GFP (PV2527) Optogenetics...AAV5 pAAV-FLEX-ArchT-tdTomato Optogenetics Ed Boyden AV-5-PV2527 99039-AAV5 pAAV-CamKII-ArchT-GFP (PV2527...-AAV9 AAV-FLEX-Arch-GFP Optogenetics Ed Boyden AV-9-PV2527 99039-AAV9 pAAV-CamKII-ArchT-GFP (PV2527) Optogenetics...PV2509 29777-AAV5 pAAV-CAG-ArchT-GFP Ed Boyden AV-9-PV2509 29777-AAV9 pAAV-CAG-ArchT-GFP Ed Boyden AV-9-PV3446...provide high-quality AAV vectors to the academic research community. The Penn Vector Core will produce viral-based...Deisseroth AV-1-36857M 100038-AAV1 pENN.AAV.hSynap.Flex.ArcLightDco.WPRE.SV40 Vincent Pieribone AV-1-36857P...36857P 100037-AAV1 pAAV.hSynap.ArcLightD.WPRE.SV40 Vincent Pieribone AV-1-51473 51473-AAV1 pAAV-hSyn1-mRuby2... -
Michael J Fox Foundation (MJFF) Plasmid Collection
TypeCollection...window) encourages researchers to assemble and share tools for Parkinson's Disease research. This collection...Neurodegeneration Research Collection , which includes other areas of this research topic. Michael J. ...Shared Research Tools Labs affiliated with MJFF have also generated a number of Shared Research Tools ... Disease Plasmid Resource MJFF Plasmids Shared Research Tools (Link opens in a new window) The Michael...SNCA , and other proteins of interest. Browse or search the table below. ID Plasmid Gene/Insert Mutations...editing tools deposited with Addgene. Browse or search the table below. ID Plasmid Description Gene/Insert... -
Rett Syndrome
TypeCollection...Broswe plasmids and other research tools for use in Rett Syndrome research....The (Link opens in a new window) Rett Syndrome Research Trust (RSRT) was launched in 2008 to drive the...Rett Syndrome plasmid resource for the scientific research community. Background Rett Syndrome Rett syndrome...account for almost 46% of all Rett syndrome cases. Research Milestones 1992 - MECP2 is discovered by Adrian...syndrome and restore functional MECP2 in cells. Search (Link opens in a new window) JAX Mice for mouse...plasmids, please see Addgene's Plasmids for Stem Cell Research page. CRISPR Tools CRISPR technology is a promising... that express or target the MECP2 gene. Use the search bar or sort buttons to find plasmids based on: ... -
Zebrafish Plasmid Collection
TypeCollection...promotes and advocates for zebrafish research in the international research community. The Latin American Zebrafish...based gene editing make the zebrafish a stalwart research model. With more than 70% of human disease genes...model system for human disease and translational research, including the study of cancer, inflammation and...plasmids containing your zebrafish gene of interest? Search Addgene's collection for plasmids that contain ...plasmids that contain tools for use in zebrafish research. This includes plasmids for genome editing, empty...Periklis Pantazis Lab Multibow: digital spectral barcodes for cell tracing - Sean Megason Lab Zebrabow -...Bimolecular fluorescence complementation (BiFC) tools - Marco Morsch Lab. A vertebrate model to study ALS-linked... -
CRISPR Guide
TypeCollection... help you get started using CRISPR in your own research. CRISPR Basics In this section, we will introduce...same chromosome. Most multiplex systems enable researchers to target anywhere from 2–7 genetic loci by cloning...later in the guide. Increasing fidelity of Cas9 Researchers have also enhanced specificity by engineering... overcome the CRISPR systems that bacteria and archaea use to protect against these foreign nucleic acids...Base Editing To overcome low HDR efficiency, researchers have developed base editors to specifically convert...Figure 5: Overview of base editing More recently, researchers have developed base editors that can catalyze...Base Edit CRISPR Prime Editing Prime editing is a “search and replace” gene editing method in which Moloney... -
Malate Dehydrogenase CUREs Community Collection
TypeCollection...mutant clones for your course-based undergraduate research experience (CURE) projects....Collection Blog post: Course-Based Undergraduate Research Experiences (CUREs) (Link opens in a new window...develops protein-centric Course-based Undergraduate Research Experiences (CUREs) centered on a single enzyme...national group of educational leaders providing research opportunities to their students and other members...educators interested in integrating MDH-related research into their teaching laboratories. They encourage...and mutants provides a shared experience for the research community and facilitates scientific collaborations...available to download from each plasmid page. Use the search bar or sort buttons to find plasmids based on: ... -
CRISPR History and Development for Genome Engineering
TypeCollection...proving to be just as useful (if not more so) for research applications, eclipsing past genome engineering...-strand break. CRISPR systems, found in 95% of archaeal and 48% of bacterial genomes, are highly diverse...proteins to the CRISPR-Cas complex. Recently, researchers have begun to use anti-CRISPRs as off-switches...activity due to rationally designed mutations. Researchers have expanded the CRISPR field beyond SpCas9,...allowing multiple Cas9s to be used together. Researchers have engineered mutant Cas enzymes with alternative...Despite the ethical controversies surrounding non-research applications, it’s clear that CRISPR is a truly...truly disruptive technology for basic research. The beauty of CRISPR is that it’s adaptable to almost any... -
Brain Initiative Collection
TypeCollection...AAV5 pAAV-CAG-FLEX-Archon1-KGC-EGFP-ER2 AAV production plasmid encoding for Archon1 fluorescent voltage...Li 115892-AAV8 pAAV-Syn-Archon1-KGC-GFP-ER2 AAV-mediated expression of Archon1-KGC-GFP-ER2 under the Syn...AAV8 pAAV-Syn-FLEX-rc [Archon1-KGC-GFP-ER2] AAV-mediated expression of Archon1-KGC-GFP-ER2 under the Syn...development of biomolecular tools for neuroscience research. Browse the BRAIN Initiative collection of plasmids...Initiative BRAIN Initiative Collection The Brain Research through Advancing Innovative Neurotechnologies...and circuits during behavior. Long desired by researchers, the revolutionary dynamic picture of the brain...emphasizes their rapid and broad dissemination to the research community. Browse plasmids , viral preps , and... -
Resolute Plasmid Collection
TypeCollection...highest-possible quality of research output, RESOLUTE expects to accelerate the pace of research in the field of ...global benefit of basic academic research as well as applied research in small biotech and pharmaceutical...mission is to develop data and reagents to boost the research focused on Solute carrier proteins (SLCs). Browse...mission is to develop data and reagents to boost the research focused on SLCs. Through the coupling of an inclusive...support from the European Union's Horizon 2020 research and innovation programme and EFPIA. Figure 1: ...Overexpression Library 213694 Superti-Furga Inducible barcoded overexpression library of human SLC proteins. ... -
Biosensor AAV Preps
TypeCollection...Li Voltage Reporter: Archon 108422 pAAV-CAG-FLEX-Archon1-KGC-EGFP-ER2 CAG Archon1 EGFP Cre dependent 5...-Syn-Archon1-KGC-GFP-ER2 Syn Archon1 EGFP Constitutive 8 Boyden 115893 pAAV-Syn-FLEX-rc [Archon1-KGC-GFP-ER2...Constitutive 9 Patriarchi 187180 pAAV_hSyn1_nLightR Syn nLightR none Constitutive 9 Patriarchi Oxytocin (OT...nLight Oxytocin (OT) Sensors GRAB_OT Voltage Sensors Archon Voltron JEDI-2P ATP Sensors iATPSnFR2 5-HT Sensors...-GFP-ER2] Syn Archon1 EGFP Cre dependent 8 Boyden Voltage Reporter: Voltron 119036 pAAV-hsyn-flex-Voltron-ST... -
Allen Institute for Cell Science Plasmid Collection
TypeCollection... for distribution to the research community. With these plasmids researchers will be able to generate ...skeletal type Sarcomeric thin filaments 114412 TTN-mEGFP AICSDP-45 mEGFP Titin Sarcomeres (M-line tag) ...mEGFP MLC-2a Sarcomeric thick filaments 114414 MYL2-mEGFP AICSDP-49 mEGFP MLC-2v Sarcomeric thick filaments...Cytoplasm 114405 ATP2A2-mEGFP AICSDP-41 mEGFP SERCA2 Sarcoplasmic reticulum/endoplasmic reticulum 114406 SMC1A-mEGFP...124607 ACTN2-mEGFP AICSDP-63 mEGFP Alpha-actinin-2 Sarcomeric z-disks 124608 NPM1-mTagRFP-T AICSDP-69 mTagRFP-T... -
Ras Pathway
TypeCollection...Laboratory for Cancer Research . Frederick National Laboratory for Cancer Research Color is used for clarity...Laboratory for Cancer Research . Frederick National Laboratory for Cancer Research Return to top Ras Pathway... Cancer Research Ras Pathway Ras Pathway You May Also Like: Ras...Farnesyltransferase, CAAX box FOS FBJ murine osteosarcoma viral oncogene homolog GRB2 Growth factor receptor...exchange factor RAS KRAS MRAS NRAS Kirsten rat sarcoma viral oncogene homolog Muscle RAS oncogene homolog...gene expression vectors for in vitro and in vivo research. The RAS Initiative - at the National Cancer Institute... -
Optogenetics Plasmid Collection
TypeCollection...membrane channels and pores derived from algae and archaebacteria, that can be opened and closed in response ...microbial opsins, such as the Halorhodopsins, Archaerhodopsins and Leptosphaeria rhodopsins, are pumps that...Guide . Interested in more news about optogenetics research? Find related posts on Addgene's blog. Microbial...Microbial Opsin Plasmids Browse, sort, or search the table below for the optogenetics plasmids for neuronal...neuronal excitation and inhibition. For example, search for "ChR mCherry", "Cre inhibition", "Boyden 2014", ...to top Optical Switch Plasmids Browse, sort, or search the table below for plasmids that use light to ...control a protein or cellular activity. For example, search "Cdc42", "transcription", "Hahn", or other terms... -
Distribution to Industry
TypeCollection...Addgene Parkinson's Research from The Michael J Fox Foundation Search Use Addgene's Search to find plasmids... Distribution to Industry Featured Collections Search Plasmids Browse Plasmids Browse Antibodies Ordering...Protein Labeling from New England Biolabs Cancer Research from Sinai Health System Plasmids from the Structural... Library Screening Messer and MJFF Created for research in Parkinson's Disease; For target validation ...open, efficient and affordable access to plasmid research tools. Pricing will be indicated on the product... -
Worm Expression Resources
TypeCollection...synthetic biology collections) for use in C. elegan research....been developed and characterized which allow researchers to express desired constructs in precise cell...highlights plasmids that contain tools for use in worm research. This includes CRISPR, RNAi, empty backbones, ...complete list of plasmids that can be used in worms, search Addgene's entire collection. ID Plasmid Description...C. elegans strains. CRISPR plasmids from John Calarco's lab as described in Heritable genome editing in...Andrew Fire Lab. A set of vectors for C. elegans research, including lacZ and GFP fusion vectors. C. elegans...computer scientists dedicated to providing the research community with accurate, current, accessible information... -
Fluorescent Protein Guide: Biosensors
TypeCollection...Lin Voltage Fluorescent voltage reporters Archon 1 and Archon 2 (Constitutive or Cre-dependent) A robotic...extracellular vs. organelle-localized). Browse or search the tables below highlighting a few popular categories...Genetically Encoded Calcium Indicators. Janelia Research Campus. Online resource. 2020 GENIE Project Calcium...: S2451-9456(16)30163-5. Teresa Alonso , Javier García-Sancho Calcium Genetically encoded calcium indicators...Nat Methods. 2023 Sep;20(9):1426-1436. Tommaso Patriarchi Norepinephrine GRAB_NE family of GPCR activation-based... Nat Methods. 2022 Feb;19(2):231-241. Tommaso Patriarchi Serotonin Red and green serotonin sensors GRAB...potentials in individual neurons and dendrites (ArcLight) Single action potentials and subthreshold electrical... -
AAVED
TypeCollection...Laboratory Gowan Tervo Janelia Research Campus Sarada Viswanathan Janelia Research Campus Kenton Woodard Penn...techonology in the lab (main issues/factors that researchers should consider when planning experiments). What...application? What are some current obstacles that researchers face right now (e.g., not enough protocols, cost...Experimental protocols or schematics. Examples of research materials to share: In vivo data: Retrograde hSyn1...Laboratory Gowan Tervo and Sarada Viswanathan, Janelia Research Campus Kenton Woodard, Penn Vector Core Intended... -
AAV Packaged on Request
TypeCollection...While our repository serves the needs of many researchers, scientists sometimes require preps beyond our...Packaged on Request service is recommended for research-grade use. Many chemogenetic, optogenetic, recombinase... methods to troubleshooting insights, you make research more reproducible for scientists everywhere and...opens in a new window) for producing high-quality research-grade viral vector preps. Data Hub Access Addgene...vectors. Our community-driven Data Hub connects researchers with troubleshooting and results that complement...Help Center Check out Addgene’s Help Center, a searchable database of information to help you every step... -
Plant Plasmids and Resources
TypeCollection...use in plants. These resources include tools for research using plant systems such as Arabidopsis, wheat...MoClo Plant Parts II and Infrastructure Kit for hierarchical assembly of plant multigene constructs - Johannes...gene of interest for expression in plants. You can search the table for features you are looking for, such...luminescent proteins for expression in plants. You can search the table for features you are looking for, such...molecular biology data for Arabidopsis thaliana research. BAR The Bio-Analytic Resource for Plant Biology...expression in the grasses. OpenPlant Synthetic Biology Research Centre (Link opens in a new window) - The initiative...