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Enter a sequence to perform a BLAST-based search of Addgene plasmid sequence databases.

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We narrowed to 18 results for: SOX

Showing: 1 - 18 of 18 results

  3. CRISPR 101: Cytosine Transversion Editors

    Type
    Blog Post
    ...binding to DNA. However, ABEs were improved by adding SOX, and GBE editing was increased even in chromatin ...to the base editor, they added the pioneer factor SOX2, which is capable of binding to and remodeling inaccessible...et al., 2022). Specifically, they found that the SOX2 activation domain (SAD), which recruits histone ...

  4. 15 Hot Plasmids from 2017

    Type
    Blog Post
    ...By replacing wild type SOX2 with either a SOX2-VP16 (strong activator) or SOX2-HP1 (strong repressor) ... the expression of transcription factors OCT3/4, SOX2, KLF4, and c-MYC is the established model for reprogramming...classic technique to elucidate the mechanism by which SOX2 acts to reprogram human fibroblasts into induced...These results argue that transcription activation by SOX2 leads to its reprogramming effects. Plasmids from... at Addgene and include a variety of cMYC, KLF4, SOX2 and OCT4 DNA binding domain and transcription activation...

  5. Donations from Addgene to Yield Answers for Rare Disease Researchers

    Type
    Blog Post
    ...Wattanasirichaigoon carried different mutations in a gene called SOX10. To understand the functional role of those mutations...cell lines and/or mouse models carrying different SOX10 mutations. More specifically, they’ve proposed to...big progress in elucidating association between SOX10 and WS4 and also several other rare genetic diseases...

  7. Delivery Methods for Generating iPSCs

    Type
    Blog Post
    ...peptide polycistronic cassette comprised of OCT4, SOX2, LIN28, NANOG, and a GFP reporter. Minicircles are...including reporters and RNAi) for:  NANOG  OCT4 SOX2 MYC KLF4 LIN28 Check out these plasmids if you...

  13. Plasmids for Stem Cell Research

    Type
    Collection
    ...pluripotent state using a cocktail of factors (Oct3/4, Sox2, c-Myc, and Klf4) that are known to maintain pluripotency...Article PI Lentivirus Human Expression of human Oct4, Sox2, Klf4, Myc, and Brd3R from five separate lentiviral.... Otonkoski Lentivirus Human Expression of human Sox2, Nanog, Oct4, and Lin28 from four separate lentiviral... Doxycycline-inducible expression of human Oct4, Sox2, Klf4, and c-Myc from four separate lentiviral plasmids...lentiviral vector for the expression of human Oct4, Sox2, and Klf4 Polycistronic lentiviral vector for "hit...lentiviral vector for the expression of human Oct4, Klf4, Sox2, and c-Myc Human Induced Pluripotent Stem Cells ...for the expression of human Oct4, Klf4, c-Myc, and Sox2 Integrative Analyses of Human Reprogramming Reveal...

  14. Validated gRNA Sequences

    Type
    Collection
    ...23918387 Chen SOX17 H. sapiens GCCCAGCCCGGCCATCACCG 59725 cut S. pyogenes 25543152 Hanna Sox17 H. sapiens...24346702 Wolfe Sox17 H. sapiens GGAGGGGCAAGGGGCGGGCG 50924 activate S. pyogenes 24346702 Wolfe Sox17 H. sapiens...GGGCAAGTACGTCGATTCCA 50926 activate S. pyogenes 24346702 Wolfe Sox17 H. sapiens GGGCGTGGGCCTAACGACGC 50923 activate S...

  15. TALENs for Endogenous Zebrafish Genes

    Type
    Collection
    ...TTGTGTGTGTGTGTGTGTgtcagtgagcagcagcTCGCCACAGTGTTGGAGA sox1a TAL3366 & TAL3367 TATAGCATGATGATGGAAacggaccttcattcccCGGGACCCCAAACCAACA sox2 (site #1) ...TGGAAACCGAGCTGAAGCccccggcgccccagcccaACACCGGGGGCACGGGGA Sox2 (site #2) TAL3368 & TAL3369 TGGTGGGGTAGACTTTCGagaaaatcggtttaaaTGTATAACATGATGGAAA sox9b TAL3180...

  16. CRISPR Plasmids - Tagging

    Type
    Collection
    ... PX458_SAP130_1 PX458_SAP130_2 SOX5 Human FLAG pFETCh_SOX5 PX458_SOX5_1 SP5 Human FLAG pFETCh_SP5 PX458...

  17. Tetracycline Inducible Expression

    Type
    Collection
    ...-OSKM Tet-On inducible expression of mouse Oct4, Sox2, Klf4, and Myc for iPS cell generation Rudolf Jaenisch...FUW-tetO-hOKMS Tet-On inducible expression of human Oct4, Sox2, Klf4, and Myc for iPS cell generation Tarjei Mikkelsen...
Showing: 1 - 18 of 18 results