We narrowed to 419 results for: RAP
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TypeBlog PostPublishedFeb. 4, 2015, 3:58 p.m....the dramatic spread of the Cas9 technology: "The rapid adoption of the Cas9 technology was also greatly...advancing this field and how we are able to support rapid progress in all areas of research. We welcome your...
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Using AAV for Neuronal Tracing
TypeBlog PostPublishedAug. 9, 2018, 1:04 p.m....memory, a special type of memory which includes autobiographical events (see Jin & Maren, 2015). Directional...could also be powerful tools for the field of gene therapy if they can reach the affected part of the brain...Labeling in the Phrenic Motor System of Adult Rats: Intrapleural Injection versus Intradiaphragmatic Injection... -
Depositor Week 2020 is Happening Now. Join us!
TypeBlog PostPublishedNov. 16, 2020, 2:15 p.m.... (Blue Flame awards and Addgene history) Friday: Wrap up! To show the magnitude of plasmid sharing over...and become available into 2021. Check out the infographic below for some Addgene depositor fun facts for... -
Grad School Advice Part 2: Building Community
TypeBlog PostPublishedOct. 6, 2016, 2:30 p.m....students. As part of this discussion, we mention graphs such as the one shown to the right that illustrate...but many students discuss the third year dip (see graph). Niroshi and Ben give their insights as to what... -
Our Most Popular Blog Posts from 2019
TypeBlog PostPublishedDec. 31, 2019, 2:26 p.m....Scientific Graphics by Beth Kenkel Find a round-up of tools you can use for making scientific graphics. PS:... -
Editor's Choice, September 2016
TypeBlog PostPublishedOct. 7, 2016, 4 p.m....and has huge potential for the development of therapeutics. It also represents a first for Addgene - while...That’s it for now. As I indicated in the opening paragraph, I’m currently on my way back from a very successful... -
London Calling - Addgene’s New Europe Office in London
TypeBlog PostPublishedJune 10, 2014, 3:20 p.m....and shared by others to develop an anti-tumour therapy using antibodies targeting dendritic cells. These...Or look at our "10 Years of Plasmid Sharing" Infographic! ... -
Chemogenetics vs. Optogenetics: Which Method Should I Choose?
TypeBlog PostPublishedJune 11, 2020, 1:34 p.m....sustained activation period is beneficial for use in therapeutic or behavioral applications where drawn out effects... by Designer Drugs): Chemogenetic Tools with Therapeutic Utility. Annual Review of Pharmacology and Toxicology... -
Fostering communication in remote collaborations
TypeBlog PostPublishedApril 21, 2020, 1:14 p.m....various tools, this may happen over email or using rapid communication tools such as Slack. Share data and...exchange project at the International Cancer Immunotherapy Conference in Frankfurt, Germany When funding... -
Addgene-Seeding Labs Plasmid Grant: Accelerating Science Globally - 5 Scientists, 4 Countries & 3 Continents!
TypeBlog PostPublishedJuly 18, 2017, 12:41 p.m.... improving expression of nutritionally and therapeutically significant proteins. In this project she aims...working in a wide range of research fields and geographical locations. We are excited to see how all of ... -
Antibodies 101: Affinity Tags
TypeBlog PostPublishedSept. 19, 2023, 1 p.m....applications. Also, purifying GST by affinity chromatography requires proper folding of the tag, which prevents...to be purified by single step metal affinity chromatography. Purification of His fusion proteins from E... -
Antibodies 101: Fc Effector Functions
TypeBlog PostPublishedMay 18, 2023, 1:15 p.m.... induce? Fc receptors are intriguing from a therapeutic standpoint. Engineered monoclonal antibodies ...phagocytosis for effective macrophage-based cancer immunotherapy.Sci. Adv.8,eabl9171(2022).DOI:10.1126/sciadv.abl9171... -
CRISPR 101: Drug discovery and CRISPR
TypeBlog PostPublishedMay 4, 2023, 1 p.m....determine if a patient would respond to an existing therapy. In theory, CRISPR could even be used to generate...Cornerstones of CRISPR-Cas in drug development and therapy. Nat Rev Drug Discov (2017) 16(2):89-100. DOI: ... -
Running for Rare Disease, Running for FOP, Running for AJ
TypeBlog PostPublishedSept. 15, 2016, 2:30 p.m....including Activin A. A commercially developed therapeutic antibody that binds Activin A and interferes ...experience is in both vaccine subunit design and therapeutic biologic design (ADCs) along with pre-clinical... -
Scientists Map the SARS-CoV-2-Human Interaction Network
TypeBlog PostPublishedApril 9, 2020, 1:15 p.m.... that can be targeted (hopefully by existing therapeutics that are safe, effective, and already FDA-approved...druggable) is a key step in our strategy to throw a therapeutic monkeywrench into the virus’ hijacking of human... -
Celebrate National Book Month with Addgene
TypeBlog PostPublishedOct. 3, 2019, 12:47 p.m...., why it affects our emotions, and even what therapeutic properties it has. As with other works of Dr.... psychology major and a musician, I found myself rapt by this book! Far from a work of glib pop psychology... -
The Importance of High Titer for AAV Transductions
TypeBlog PostPublishedMarch 1, 2018, 2:11 p.m....Integration. Molecular therapy : the journal of the American Society of Gene Therapy. 2008;16(7):1189-1199... -
DAP arrays for multiplex gene editing
TypeBlog PostPublishedJuly 7, 2022, 1:15 p.m....for a higher number of MPE. Therapeutic potential To explore the therapeutic potential of the DAP array... -
Addgene Depositors Get More Citations
TypeBlog PostPublishedApril 20, 2017, 2:30 p.m....highly cited, we went to one of the largest bibliographic databases available, Web of Science. For each... publication, Web of Science provides basic bibliographic information and uses its vast network of articles... -
Cultivating Community Science at BosLab
TypeBlog PostPublishedNov. 2, 2017, 1:35 p.m....proof-of-concept experiments for discovering novel therapeutics. Dave is a chemical biologist with a Ph.D. from... first yeast transformations! Dennis Oleksyuk, Raphael Laurenceau, and Tami Pudina have initiated a soil...