...membrane channels and pores derived from algae and archaebacteria, that can be opened and closed in response ...microbial opsins, such as the Halorhodopsins, Archaerhodopsins and Leptosphaeria rhodopsins, are pumps that...Guide . Interested in more news about optogenetics research? Find related posts on Addgene's blog. Microbial...Microbial Opsin Plasmids Browse, sort, or search the table below for the optogenetics plasmids for neuronal...neuronal excitation and inhibition. For example, search for "ChR mCherry", "Cre inhibition", "Boyden 2014", ...to top Optical Switch Plasmids Browse, sort, or search the table below for plasmids that use light to ...control a protein or cellular activity. For example, search "Cdc42", "transcription", "Hahn", or other terms...

...highest-possible quality of research output, RESOLUTE expects to accelerate the pace of research in the field of ...global benefit of basic academic research as well as applied research in small biotech and pharmaceutical...mission is to develop data and reagents to boost the research focused on Solute carrier proteins (SLCs). Browse...mission is to develop data and reagents to boost the research focused on SLCs. Through the coupling of an inclusive...support from the European Union's Horizon 2020 research and innovation programme and EFPIA. Figure 1: ...

...Addgene Parkinson's Research from The Michael J Fox Foundation Search Use Addgene's Search to find plasmids... Distribution to Industry Featured Collections Search Plasmids Browse Plasmids Browse Antibodies Ordering...Protein Labeling from New England Biolabs Cancer Research from Sinai Health System Plasmids from the Structural... Library Screening Messer and MJFF Created for research in Parkinson's Disease; For target validation ...open, efficient and affordable access to plasmid research tools. Pricing will be indicated on the product...

...possible function of a protein of interest. Browse or search the table below to find markers of general cellular... Cooper *Fusions to other FPs can be found by searching the complete Michael Davidson Fluorescent Protein...necessary for movement and cell division. Browse or search the table below to find markers of cytoskeletal... Bement *Fusions to other FPs can be found by searching the complete Michael Davidson Fluorescent Protein...junctions, tight junctions, and desmosomes. Browse or search the table below to find markers for cellular junctions...Fanning *Fusions to other FPs can be found by searching the complete Michael Davidson Fluorescent Protein...post-translational modification to function properly. Browse or search the table below to find markers of secretory pathway...

...Laboratory Gowan Tervo Janelia Research Campus Sarada Viswanathan Janelia Research Campus Kenton Woodard Penn...techonology in the lab (main issues/factors that researchers should consider when planning experiments). What...application? What are some current obstacles that researchers face right now (e.g., not enough protocols, cost...Experimental protocols or schematics. Examples of research materials to share: In vivo data: Retrograde hSyn1...Laboratory Gowan Tervo and Sarada Viswanathan, Janelia Research Campus Kenton Woodard, Penn Vector Core Intended...

...synthetic biology collections) for use in C. elegan research....been developed and characterized which allow researchers to express desired constructs in precise cell...highlights plasmids that contain tools for use in worm research. This includes CRISPR, RNAi, empty backbones, ...complete list of plasmids that can be used in worms, search Addgene's entire collection. ID Plasmid Description...Andrew Fire Lab. A set of vectors for C. elegans research, including lacZ and GFP fusion vectors. C. elegans...computer scientists dedicated to providing the research community with accurate, current, accessible information...

...While our repository serves the needs of many researchers, scientists sometimes require preps beyond our...Packaged on Request service is recommended for research-grade use. Many chemogenetic, optogenetic, recombinase... methods to troubleshooting insights, you make research more reproducible for scientists everywhere and...opens in a new window) for producing high-quality research-grade viral vector preps. Data Hub Access Addgene...vectors. Our community-driven Data Hub connects researchers with troubleshooting and results that complement...Help Center Check out Addgene’s Help Center, a searchable database of information to help you every step...

...use in plants. These resources include tools for research using plant systems such as Arabidopsis, wheat...MoClo Plant Parts II and Infrastructure Kit for hierarchical assembly of plant multigene constructs - Johannes...gene of interest for expression in plants. You can search the table for features you are looking for, such...luminescent proteins for expression in plants. You can search the table for features you are looking for, such...molecular biology data for Arabidopsis thaliana research. BAR The Bio-Analytic Resource for Plant Biology...expression in the grasses. OpenPlant Synthetic Biology Research Centre (Link opens in a new window) - The initiative...

...Laboratory for Cancer Research . Frederick National Laboratory for Cancer Research Color is used for clarity...Laboratory for Cancer Research . Frederick National Laboratory for Cancer Research Return to top Ras Pathway... Cancer Research Ras Pathway Ras Pathway You May Also Like: Ras...gene expression vectors for in vitro and in vivo research. The RAS Initiative - at the National Cancer Institute...

...used for research, it is the lentiviral genome that encodes genetic material that the researcher wants delivered...most common and useful types of viruses used in research. Lentivirus can transduce both dividing and non-dividing...available at Addgene have been designed for increased researcher safety. Read our Lentiviral Guide for more information...Plasmids One safety feature of lentivirus used in research is that the components necessary to produce an...Please see our CRISPR Empty gRNA plasmids table and search "lenti". ID Plasmid Generation Description PI 8453...

...Plasmid Collection (Link opens in a new window) Researchers developing novel diagnostics, therapeutics, and...important experiments. In an effort to speed up research of SARS-CoV-2, Ginkgo Bioworks (Link opens in ...synthesis capabilities, in collaboration with researchers at Stanford University’s Department of Bioengineering...Bioengineering, to build DNA that will enable researchers to express SARS-CoV-2 viral proteins in several ...validated by Ginkgo or Addgene. Plasmids Use the search bar or sort buttons to find SARS-CoV-2 and common...

...Disease Research Find deposited plasmids for specific disease research areas. Cancer Research Plasmids...Collection Neuroendocrine Tumor Research Foundation Neurodegeneration Research Collection Rett Syndrome Plasmid...

...intruders, antibodies are also extremely useful to researchers in a lab. When an antibody binds tightly to a...name a few. Traditional sources of antibodies for research purposes include animals or hybridoma cells, but...antibodies extensively validated for neuroscience research applications from the NeuroMab/Trimmer Lab Recombinant...expression of antibodies, nanobodies or ScFvs. Use the search bar or sort buttons to find antibody plasmids for...Nanobodies, Sybodies, or ScFVs Secondary antibodies (search for "anti-mouse" or "anti-rabbit") ID Plasmid Description...

...with fairly high specificity. Fifteen years of research has shown that when fused to a nuclease or activation...interview with Adam Bogdanove ), progress on TALe research has been swift. The incentives are high. Since...potential targetable sites approximately every 35bp. Researchers are still determining the importance of context...matter of days. In an open access Nucleic Acids Research article that came out in the spring of 2011, the...labs that continue to hone these tools and the researchers who are learning to wield them. Learn more about...

...Protein Tagging Plasmids for Stem Cell Research Neurodegeneration Research Collection The iPSC Neurodegenerative...from this effort will be broadly shared with the research community. To this end, all plasmids that result...the project efforts will be made available for research purposes in the iNDI plasmid collection at Addgene...

...replicate plasmids of all types, but beyond that, researchers also use bacteria like E. coli and their relatively...to help you harness bacterial genomes for your research. Plasmid ID Technique PI Purpose pCas9 42876 CRISPR...Purpose pRU Series Various Plasmids Cloned by researcher Fluorescent protein, GUS, and LacZ Derivatives... One-Hybrid Series Various Plasmids Cloned by researcher Growth of strain USO hisB- pyrF- rpoZ- on plates...Reagents Kit Various Plasmids Sequence chosen by researcher Beta-galactosidase Keith Joung Transcription ...

...Find prime editor plasmids for (search and replace) genome editing....Design Tools CRISPR Blog Posts Prime editing is a “search and replace” gene editing method in which a reverse...tool from Hyongbum Kim's lab . Browse, sort, or search the tables below for CRISPR prime editing plasmids...editing are highlighted in the table below. Use the search bar to find a gRNA vector based on expression system...

...alleles. To introduce specific genomic changes, researchers use ssDNA or dsDNA repair templates with homology...Epigenetics To make targeted epigenetic modifications, researchers have fused catalytically dead dCas9 to epigenetic... tables on Addgene's Empty gRNA Vectors page to search based on factors such as selectable marker or cloning...mammalian vectors, simply type "Mammalian" into the search bar. When using CRISPR, you will need to express...

...recombinant antibodies to help facilitate scientific research. We are building a collection of affinity reagents...Addgene values transparency and accessibility in research and therefore makes the sequences of these affinity...of antibodies developed and validated for many research applications. Browse Antibodies Production Interested...

...Addgene values transparency and accessibility in research. For each antibody, we provide important details...their use, visit our Antibody Guide . Browse or search the table below or visit the following pages to...Antibodies targeting proteins for neuroscience research. Institute for Protein Innovation Collection :...