We narrowed to 40 results for: Cit

...non-coding RNA elements capable of programming the specificity of the CRISPR-mediated nucleic acid cleavage....10.1126/science.1231143. PubMed . DNA targeting specificity of RNA-guided Cas9 nucleases. Hsu PD, Scott DA...RNA-guided CRISPR Cas9 for enhanced genome editing specificity. Ran FA, Hsu PD, Lin CY, Gootenberg JS, Konermann...

...in the 2009 Joung Nature Protocols paper . How to Cite this Kit These plasmids were created by your colleagues.... Please acknowledge the Principal Investigator, cite the article in which they were created, and include...

...hybridoma-derived equivalent to ensure that potency and specificity have been retained. If the target antigen is ...pattern is compared to the mRNA expression pattern cited in the Tissue Atlas (Link opens in a new window)...

...behavior and emotion, uncontrolled movements, memory deficits, as well as difficulty speaking and swallowing...cause of dementia. Symptoms include memory loss, deficits in decision-making, and language abilities. The...

...Sciences has screened thousands of enhancers for specificity and brightness of fluorescent labeling across...collection includes the top vectors with the highest specificity and brightness, assessed using ssRNAseq or high-resolution...

... VP16 transcriptional activation domain). For simplicity, other promoter elements and transcription machinery...and tTA. Dox has good tissue distribution, low toxicity, a known half-life (24 hours), and is relatively...

...including that it is easy to implement due to the simplicity of gRNA design, programmable for different genomic...

...CRISPR-associated transposases (CASTs) combine the large-scale capacity of transposases (Tns) with the precise DNA-targeting...

... your colleagues, sequence-verified, and widely cited in publications. All pricing includes DNA amplification...

...experiments, both in vitro and in vivo. It has low immunogenicity, is easy to use, and can be safely handled ...

...below for the optogenetics plasmids for neuronal excitation and inhibition. For example, search for "ChR ...

...generates light that activates the opsin to either excite or inhibit the target neuron. LMO can be activated...

...plasmids with a cargo that may reduce titer due to toxicity or other reasons For these cases, Addgene will...

... for gene delivery due to their high packaging capacity, high efficiency in driving strong transient gene...

... WPRE has been removed to increase the cloning capacity. pCDH-CB-IRES-copGFP-T2A-Puro 72299 Express gene...

...DUSP DUSP1 DUSP2 DUSP3 DUSP4 DUSP5 DUSP6 Dual specificity phosphatase E2F E2F1 E2F2 E2F3 E2F transcription...

...TALENs bind and cleave DNA in pairs. Binding specificity is determined by customizable arrays of polymorphic...

...plasmids available in Addgene's collection. Opsin Excitatory Wild-type ChR2 ChR2/H134R soCoChR ChR2/other ...

...DREADD Bryan Roth 65417 pAAV-hSyn-dF-HA-KORD-IRES-mCitrine Syn Inhibitor DREADD Bryan Roth 154867 pAAV-hSyn-fDIO-hM4D...

...Description PI 65417-AAV8 pAAV-hSyn-dF-HA-KORD-IRES-mCitrine AAV packaging vector for hSyn driven KOR DREADD...