Skip to main content
Addgene
Showing: 41 - 60 of 75 results
  1. Ras Pathway

    Type
    Collection
    ...regulating the growth of the cell, however when mutations occur in the Ras gene it can be stuck in a constitutively...PubMed PMID: 17428555 . RAS signaling pathways, mutations and their role in colorectal cancer. Zenonos K...
  2. Tetracycline Inducible Expression

    Type
    Collection
    ...On System In 1995, Gossen et al. used random mutagenesis to identify which amino acid residues of tetR...important for tetracycline-dependent repression. Mutating these residues led to the development of a reverse...
  3. CRISPR Plasmids - Tagging

    Type
    Collection
    ...systematic and scalable method to create marker-free mutations, insertions, and deletions at any locus in C. ... 10-day protocol, generates “clean” homozygous mutants with no co-integrated markers or footprints, and...
  4. Retrograde AAV viral preps

    Type
    Collection
    ...Norepinephrine sensor Li 123310 pAAV-hSyn-GRAB_NEmut Syn GRAB-NEmut control norepinephrine sensor (does not...
  5. CRISPR Pooled gRNA Libraries

    Type
    Collection
    ...with the pooled library to create a population of mutant cells that are then screened for a phenotype of...Human Wei 3rd Varies 12,472 pairs HR700_TP53 Exon Mutation Libraries 229137–229140 Donor Vector Human Stiewe...
  6. CRISPR Plasmids - Empty gRNA Vectors

    Type
    Collection
    ...sgUPRT 54467 Other/Toxoplasma gondii none, Q5 mutagenesis yes, cut S. pyogenes Sibley pU6-Universal 52694...Gateway recombination. Qi Multiplex Conditional Mutagenesis Using Transgenic Expression of Cas9 and sgRNAs...
  7. Immunology Research Plasmids and Resources

    Type
    Collection
    ...arginine-rich, mutated in early stage tumors ARP, MANF, MGC142148, MGC142150 ARMETL1 arginine-rich, mutated in early..., DC-SIGN, DC-SIGN1, MGC129965 CD4 CD4 molecule CD4mut CD74 CD74 molecule, major histocompatibility complex...FLJ79544, FLJ94613, MGC138597, T3G CD4 CD4 molecule CD4mut CD40LG CD40 ligand CD154, CD40L, HIGM1, IGM, IMD3...consists of 182 wild-type and 19 well-characterized mutant ORFs that represent over 25 cellular signaling ...
  8. Browse

    Type
    Collection
    ...Plasmids Plasmid Gene/Insert Vector Type Backbone Mutations Tags Industry PI...
  9. CRISPR Plasmids - RNA Editing

    Type
    Collection
    ...making it a very flexible editing system. The T375G mutation reduces off-target effects of ADAR2 by destabilizing...
  10. CRISPR Plasmids and Resources

    Type
    Collection
    ...enzymes generate double strand breaks (DSBs). Nick Mutated Cas nickase enzymes generate single-strand DNA ...
  11. FlyCRISPR

    Type
    Collection
    ... chiRNA plasmid can be coinjected to generate mutations via imperfectly repaired DSBs. Coinjection of ...
  12. Resolute Plasmid Collection

    Type
    Collection
    ...approximately 450 identified members. Many SLCs have mutations associated with disease and could become targets...
  13. Mammalian RNAi Tools

    Type
    Collection
    ...or to knockdown genes with potentially harmful mutations in therapeutic settings. As a tool in mammalian...
Showing: 41 - 60 of 75 results