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Addgene

Enter a sequence to perform a BLAST-based search of Addgene plasmid sequence databases.

In Category

We narrowed to 9 results for: ada

Showing: 1 - 9 of 9 results

  1. CRISPR Guide

    Type
    Guide
    ...Escherichia coli TadA, a tRNA adenosine deaminase. Like cytosine base editors, the evolved TadA domain is fused...on a second ADAR variant that displays improved specificity, and editors carrying an ADAR truncation that...break, Cas3 initiates single-strand DNA degradation. This degradation can continue for many kilobases in one...Publications CRISPR Overview Bacteria have an interesting adaptive immune response that detects and eliminates foreign...target. Due to its comparative simplicity and adaptability, CRISPR rapidly became the most popular genome...inhibiting Cas9’s endonuclease domain; or inducing degradation of the Cas9 protein. Most Acr proteins are specific... or dCas9 to create the adenine base editor. The TadA domain has also been further evolved to catalyze...

  2. Chemogenetics Guide

    Type
    Guide
    ... 25587888 (Link opens in a new window) Coward P, Wada HG, Falk MS, Chan SD, Meng F, et al. (1998). Controlling...opens in a new window) Farrell MS, Pei Y, Wan Y, Yadav PN, Daigle TL, Urban DJ, Lee H-M, Sciaky N, Simmons...Shimojo M, Zhang M-R, Tomita Y, Nakahara J, Suhara T, Takada M, Higuchi M, Jin J, Roth BL, Minamimoto T (2020...

  3. Plan Your Experiment

    Type
    Guide
    ...different Cas proteins available, and researchers can adapt these experiments for different organisms. This .... D., Dionne, D., Burks, T., Raychowdhury, R., Adamson, B., Norman, T. M., Lander, E. S., Weissman, J....PMID: 35941224 Gilbert, L. A., Horlbeck, M. A., Adamson, B., Villalta, J. E., Chen, Y., Whitehead, E. H...

  4. Adenovirus Guide

    Type
    Guide
    ...immunogenic because they activate both innate and adaptive immune responses in the host. More than 80% of...structural capsid proteins. Glossary Term Definition Adaptive immunity Specific and long-lasting immune response...

  5. Science Guides

    Type
    Guide
    ...alindromic R epeat (CRISPR) systems, which form an adaptive immune system in bacteria, have been modified ...

  6. Promoters

    Type
    Guide
    ...transcribes genes encoding transfer RNAs (tRNA), the adaptor molecules that are responsible for bringing amino...

  7. Cloning

    Type
    Guide
    ... website. Ligation Independent Cloning (Figure adapted from LIC protocol ) Back to Top Yeast-mediated ...

  8. Modular Cloning Guide

    Type
    Guide
    ... 2.0 Genome Engineering, TALEN Daniel Voytas and Adam Bogdanove Plasmid toolkit to efficiently assemble...
Showing: 1 - 9 of 9 results