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GFP-HP1alpha Citations (17)

Originally described in: Maintenance of stable heterochromatin domains by dynamic HP1 binding.
Cheutin T, McNairn AJ, Jenuwein T, Gilbert DM, Singh PB, Misteli T Science. 2003 Jan 31. 299(5607):721-5.
PubMed Journal

Articles Citing GFP-HP1alpha

DNA-damage response in chromatin of ribosomal genes and the surrounding genome. Foltankova V, Legartova S, Kozubek S, Hofer M, Bartova E. Gene. 2013 Jun 15;522(2):156-67. doi: 10.1016/j.gene.2013.03.108. Epub 2013 Apr 6. PubMed
A novel role of PRR14 in the regulation of skeletal myogenesis. Yang M, Yuan ZM. Cell Death Dis. 2015 Apr 23;6:e1734. doi: 10.1038/cddis.2015.103. PubMed
CCAR2/DBC1 is required for Chk2-dependent KAP1 phosphorylation and repair of DNA damage. Magni M, Ruscica V, Restelli M, Fontanella E, Buscemi G, Zannini L. Oncotarget. 2015 Jul 10;6(19):17817-31. PubMed
Spatiotemporal regulation of Heterochromatin Protein 1-alpha oligomerization and dynamics in live cells. Hinde E, Cardarelli F, Gratton E. Sci Rep. 2015 Aug 4;5:12001. doi: 10.1038/srep12001. PubMed
Actin cytoskeleton differentially alters the dynamics of lamin A, HP1alpha and H2B core histone proteins to remodel chromatin condensation state in living cells. Toh KC, Ramdas NM, Shivashankar GV. Integr Biol (Camb). 2015 Oct;7(10):1309-17. doi: 10.1039/c5ib00027k. Epub 2015 Sep 11. PubMed
Local enrichment of HP1alpha at telomeres alters their structure and regulation of telomere protection. Chow TT, Shi X, Wei JH, Guan J, Stadler G, Huang B, Blackburn EH. Nat Commun. 2018 Sep 4;9(1):3583. doi: 10.1038/s41467-018-05840-y. PubMed
CRISPR-Mediated Programmable 3D Genome Positioning and Nuclear Organization. Wang H, Xu X, Nguyen CM, Liu Y, Gao Y, Lin X, Daley T, Kipniss NH, La Russa M, Qi LS. Cell. 2018 Nov 15;175(5):1405-1417.e14. doi: 10.1016/j.cell.2018.09.013. Epub 2018 Oct 11. PubMed

Associated Plasmids

Liquid Nuclear Condensates Mechanically Sense and Restructure the Genome. Shin Y, Chang YC, Lee DSW, Berry J, Sanders DW, Ronceray P, Wingreen NS, Haataja M, Brangwynne CP. Cell. 2018 Nov 29;175(6):1481-1491.e13. doi: 10.1016/j.cell.2018.10.057. PubMed

Associated Plasmids

DNA Damage Changes Distribution Pattern and Levels of HP1 Protein Isoforms in the Nucleolus and Increases Phosphorylation of HP1beta-Ser88. Legartova S, Lochmanova G, Zdrahal Z, Kozubek S, Sponer J, Krepl M, Pokorna P, Bartova E. Cells. 2019 Sep 17;8(9). pii: cells8091097. doi: 10.3390/cells8091097. PubMed
Unphosphorylated STAT3 in heterochromatin formation and tumor suppression in lung cancer. Dutta P, Zhang L, Zhang H, Peng Q, Montgrain PR, Wang Y, Song Y, Li J, Li WX. BMC Cancer. 2020 Feb 22;20(1):145. doi: 10.1186/s12885-020-6649-2. PubMed
TALEN outperforms Cas9 in editing heterochromatin target sites. Jain S, Shukla S, Yang C, Zhang M, Fatma Z, Lingamaneni M, Abesteh S, Lane ST, Xiong X, Wang Y, Schroeder CM, Selvin PR, Zhao H. Nat Commun. 2021 Jan 27;12(1):606. doi: 10.1038/s41467-020-20672-5. PubMed
HP1alpha is a chromatin crosslinker that controls nuclear and mitotic chromosome mechanics. Strom AR, Biggs RJ, Banigan EJ, Wang X, Chiu K, Herman C, Collado J, Yue F, Ritland Politz JC, Tait LJ, Scalzo D, Telling A, Groudine M, Brangwynne CP, Marko JF, Stephens AD. Elife. 2021 Jun 9;10. pii: 63972. doi: 10.7554/eLife.63972. PubMed

Associated Plasmids

Interrogation of the dynamic properties of higher-order heterochromatin using CRISPR-dCas9. Gao Y, Han M, Shang S, Wang H, Qi LS. Mol Cell. 2021 Aug 13. pii: S1097-2765(21)00612-2. doi: 10.1016/j.molcel.2021.07.034. PubMed

Associated Plasmids

Heterochromatic repeat clustering imposes a physical barrier on homologous recombination to prevent chromosomal translocations. Mitrentsi I, Lou J, Kerjouan A, Verigos J, Reina-San-Martin B, Hinde E, Soutoglou E. Mol Cell. 2022 Jun 2;82(11):2132-2147.e6. doi: 10.1016/j.molcel.2022.03.033. Epub 2022 Apr 20. PubMed
Wiskott-Aldrich syndrome protein forms nuclear condensates and regulates alternative splicing. Yuan B, Zhou X, Suzuki K, Ramos-Mandujano G, Wang M, Tehseen M, Cortes-Medina LV, Moresco JJ, Dunn S, Hernandez-Benitez R, Hishida T, Kim NY, Andijani MM, Bi C, Ku M, Takahashi Y, Xu J, Qiu J, Huang L, Benner C, Aizawa E, Qu J, Liu GH, Li Z, Yi F, Ghosheh Y, Shao C, Shokhirev M, Comoli P, Frassoni F, Yates JR 3rd, Fu XD, Esteban CR, Hamdan S, Izpisua Belmonte JC, Li M. Nat Commun. 2022 Jun 25;13(1):3646. doi: 10.1038/s41467-022-31220-8. PubMed
Dynamic Heterochromatin States in Anisotropic Nuclei of Cells on Aligned Nanofibers. Liu W, Padhi A, Zhang X, Narendran J, Anastasio MA, Nain AS, Irudayaraj J. ACS Nano. 2022 Jul 8. doi: 10.1021/acsnano.2c02660. PubMed
Mechanomemory in protein diffusivity of chromatin and nucleoplasm after force cessation. Rashid F, Liu W, Wang Q, Ji B, Irudayaraj J, Wang N. Proc Natl Acad Sci U S A. 2023 Mar 28;120(13):e2221432120. doi: 10.1073/pnas.2221432120. Epub 2023 Mar 21. PubMed

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