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pHAGE TRE dCas9-KRAB Citations (15)

Plasmid Article: Cas9 effector-mediated regulation of transcription and differentiation in human pluripotent stem cells.
Kearns NA, Genga RM, Enuameh MS, Garber M, Wolfe SA, Maehr R Development. 2014 Jan;141(1):219-23. doi: 10.1242/dev.103341.
PubMed Journal

Articles Citing pHAGE TRE dCas9-KRAB

Transcriptional Regulation with CRISPR/Cas9 Effectors in Mammalian Cells. Pham H, Kearns NA, Maehr R. Methods Mol Biol. 2016;1358:43-57. doi: 10.1007/978-1-4939-3067-8_3. PubMed

Associated Plasmids

Controlling transcription in human pluripotent stem cells using CRISPR-effectors. Genga RM, Kearns NA, Maehr R. Methods. 2015 Oct 23. pii: S1046-2023(15)30132-8. doi: 10.1016/j.ymeth.2015.10.014. PubMed
Novel Small-Molecule CX3CR1 Antagonist Impairs Metastatic Seeding and Colonization of Breast Cancer Cells. Shen F, Zhang Y, Jernigan DL, Feng X, Yan J, Garcia FU, Meucci O, Salvino JM, Fatatis A. Mol Cancer Res. 2016 Jun;14(6):518-27. doi: 10.1158/1541-7786.MCR-16-0013. Epub 2016 Mar 21. PubMed
Evaluating Synthetic Activation and Repression of Neuropsychiatric-Related Genes in hiPSC-Derived NPCs, Neurons, and Astrocytes. Ho SM, Hartley BJ, Flaherty E, Rajarajan P, Abdelaal R, Obiorah I, Barretto N, Muhammad H, Phatnani HP, Akbarian S, Brennand KJ. Stem Cell Reports. 2017 Aug 8;9(2):615-628. doi: 10.1016/j.stemcr.2017.06.012. Epub 2017 Jul 27. PubMed

Associated Plasmids

The p53-inducible long noncoding RNA TRINGS protects cancer cells from necrosis under glucose starvation. Khan MR, Xiang S, Song Z, Wu M. EMBO J. 2017 Dec 1;36(23):3483-3500. doi: 10.15252/embj.201696239. Epub 2017 Oct 18. PubMed
Dismissal of RNA Polymerase II Underlies a Large Ligand-Induced Enhancer Decommissioning Program. Tan Y, Jin C, Ma W, Hu Y, Tanasa B, Oh S, Gamliel A, Ma Q, Yao L, Zhang J, Ohgi K, Liu W, Aggarwal AK, Rosenfeld MG. Mol Cell. 2018 Aug 16;71(4):526-539.e8. doi: 10.1016/j.molcel.2018.07.039. PubMed
The lncRNA TP73-AS1 is linked to aggressiveness in glioblastoma and promotes temozolomide resistance in glioblastoma cancer stem cells. Mazor G, Levin L, Picard D, Ahmadov U, Caren H, Borkhardt A, Reifenberger G, Leprivier G, Remke M, Rotblat B. Cell Death Dis. 2019 Mar 13;10(3):246. doi: 10.1038/s41419-019-1477-5. PubMed
SIGMAR1/Sigma-1 receptor ablation impairs autophagosome clearance. Yang H, Shen H, Li J, Guo LW. Autophagy. 2019 Sep;15(9):1539-1557. doi: 10.1080/15548627.2019.1586248. Epub 2019 Mar 14. PubMed
A piggyBac-based toolkit for inducible genome editing in mammalian cells. Schertzer MD, Thulson E, Braceros KCA, Lee DM, Hinkle ER, Murphy RM, Kim SO, Vitucci EM, Calabrese JM. RNA. 2019 May 17. pii: rna.068932.118. doi: 10.1261/rna.068932.118. PubMed

Associated Plasmids

A Yeast Suppressor Screen Used To Identify Mammalian SIRT1 as a Proviral Factor for Middle East Respiratory Syndrome Coronavirus Replication. Weston S, Matthews KL, Lent R, Vlk A, Haupt R, Kingsbury T, Frieman MB. J Virol. 2019 Jul 30;93(16). pii: JVI.00197-19. doi: 10.1128/JVI.00197-19. Print 2019 Aug 15. PubMed
Chromatin Remodeling in Response to BRCA2-Crisis. Gruber JJ, Chen J, Geller B, Jager N, Lipchik AM, Wang G, Kurian AW, Ford JM, Snyder MP. Cell Rep. 2019 Aug 20;28(8):2182-2193.e6. doi: 10.1016/j.celrep.2019.07.057. PubMed
Cooperation of cancer drivers with regulatory germline variants shapes clinical outcomes. Musa J, Cidre-Aranaz F, Aynaud MM, Orth MF, Knott MML, Mirabeau O, Mazor G, Varon M, Holting TLB, Grossetete S, Gartlgruber M, Surdez D, Gerke JS, Ohmura S, Marchetto A, Dallmayer M, Baldauf MC, Stein S, Sannino G, Li J, Romero-Perez L, Westermann F, Hartmann W, Dirksen U, Gymrek M, Anderson ND, Shlien A, Rotblat B, Kirchner T, Delattre O, Grunewald TGP. Nat Commun. 2019 Sep 11;10(1):4128. doi: 10.1038/s41467-019-12071-2. PubMed
Functional Enhancers Shape Extrachromosomal Oncogene Amplifications. Morton AR, Dogan-Artun N, Faber ZJ, MacLeod G, Bartels CF, Piazza MS, Allan KC, Mack SC, Wang X, Gimple RC, Wu Q, Rubin BP, Shetty S, Angers S, Dirks PB, Sallari RC, Lupien M, Rich JN, Scacheri PC. Cell. 2019 Nov 27;179(6):1330-1341.e13. doi: 10.1016/j.cell.2019.10.039. Epub 2019 Nov 21. PubMed
Integrin alpha-5 subunit is critical for the early stages of human pluripotent stem cell cardiac differentiation. Neiman G, Scarafia MA, La Greca A, Santin Velazque NL, Garate X, Waisman A, Mobbs AM, Kasai-Brunswick TH, Mesquita F, Martire-Greco D, Moro LN, Luzzani C, Bastos Carvalho A, Sevlever GE, Campos de Carvalho A, Guberman AS, Miriuka SG. Sci Rep. 2019 Dec 2;9(1):18077. doi: 10.1038/s41598-019-54352-2. PubMed
The PAX-SIX-EYA-DACH network modulates GATA-FOG function in fly hematopoiesis and human erythropoiesis. Creed TM, Baldeosingh R, Eberly CL, Schlee CS, Kim M, Cutler JA, Pandey A, Civin CI, Fossett NG, Kingsbury TJ. Development. 2020 Jan 3;147(1). pii: dev.177022. doi: 10.1242/dev.177022. PubMed

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