pCW57-MCS1-P2A-MCS2 (Blast) Citations (24)
Originally described in: Pan-Cancer Analyses Reveal Genomic Features of FOXM1 Overexpression in Cancer.Barger CJ, Branick C, Chee L, Karpf AR Cancers (Basel). 2019 Feb 21;11(2). pii: cancers11020251. doi: 10.3390/cancers11020251. PubMed Journal
Articles Citing pCW57-MCS1-P2A-MCS2 (Blast)
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| DDK Has a Primary Role in Processing Stalled Replication Forks to Initiate Downstream Checkpoint Signaling. Sasi NK, Coquel F, Lin YL, MacKeigan JP, Pasero P, Weinreich M. Neoplasia. 2018 Oct;20(10):985-995. doi: 10.1016/j.neo.2018.08.001. Epub 2018 Aug 26. PubMed |
| Transmembrane insertases and N-glycosylation critically determine synthesis, trafficking and activity of the nonselective cation channel TRPC6. Talbot BE, Vandorpe DH, Stotter BR, Alper SL, Schlondorff JS. J Biol Chem. 2019 Jul 2. pii: RA119.008299. doi: 10.1074/jbc.RA119.008299. PubMed |
| Phosphorylated Lamin A/C in the Nuclear Interior Binds Active Enhancers Associated with Abnormal Transcription in Progeria. Ikegami K, Secchia S, Almakki O, Lieb JD, Moskowitz IP. Dev Cell. 2020 Mar 23;52(6):699-713.e11. doi: 10.1016/j.devcel.2020.02.011. PubMed |
| NOTCH1 activation compensates BRCA1 deficiency and promotes triple-negative breast cancer formation. Miao K, Lei JH, Valecha MV, Zhang A, Xu J, Wang L, Lyu X, Chen S, Miao Z, Zhang X, Su SM, Shao F, Rajendran BK, Bao J, Zeng J, Sun H, Chen P, Tan K, Chen Q, Wong KH, Xu X, Deng CX. Nat Commun. 2020 Jun 26;11(1):3256. doi: 10.1038/s41467-020-16936-9. PubMed |
| CCAAT/Enhancer-Binding Protein Delta (C/EBPdelta): A Previously Unrecognized Tumor Suppressor that Limits the Oncogenic Potential of Pancreatic Ductal Adenocarcinoma Cells. Hartl L, Duitman J, Aberson HL, Chen K, Dijk F, Roelofs JJTH, Dings MPG, Hooijer GKJ, Hernanda PY, Pan Q, Busch OR, Besselink MGH, Boerman T, Peppelenbosch MP, Bijlsma MF, Spek CA. Cancers (Basel). 2020 Sep 7;12(9). pii: cancers12092546. doi: 10.3390/cancers12092546. PubMed |
| KRAS-regulated glutamine metabolism requires UCP2-mediated aspartate transport to support pancreatic cancer growth. Raho S, Capobianco L, Malivindi R, Vozza A, Piazzolla C, De Leonardis F, Gorgoglione R, Scarcia P, Pezzuto F, Agrimi G, Barile SN, Pisano I, Reshkin SJ, Greco MR, Cardone RA, Rago V, Li Y, Marobbio CMT, Sommergruber W, Riley CL, Lasorsa FM, Mills E, Vegliante MC, De Benedetto GE, Fratantonio D, Palmieri L, Dolce V, Fiermonte G. Nat Metab. 2020 Dec;2(12):1373-1381. doi: 10.1038/s42255-020-00315-1. Epub 2020 Nov 23. PubMed |
| xCT/SLC7A11 antiporter function inhibits HIV-1 infection. Rabinowitz J, Sharifi HJ, Martin H, Marchese A, Robek M, Shi B, Mongin AA, de Noronha CMC. Virology. 2021 Apr;556:149-160. doi: 10.1016/j.virol.2021.01.008. Epub 2021 Jan 20. PubMed |
Co-regulation and function of FOXM1/RHNO1 bidirectional genes in cancer.
Barger CJ, Chee L, Albahrani M, Munoz-Trujillo C, Boghean L, Branick C, Odunsi K, Drapkin R, Zou L, Karpf AR.
Elife. 2021 Apr 23;10. pii: 55070. doi: 10.7554/eLife.55070.
PubMed
Associated Plasmids |
| RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy. Radaszkiewicz T, Noskova M, Gomoryova K, Vondalova Blanarova O, Radaszkiewicz KA, Pickova M, Vichova R, Gybel T, Kaiser K, Demkova L, Kucerova L, Barta T, Potesil D, Zdrahal Z, Soucek K, Bryja V. Elife. 2021 Oct 27;10. pii: 65759. doi: 10.7554/eLife.65759. PubMed |
| Folliculin impairs breast tumor growth by repressing TFE3-dependent induction of the Warburg effect and angiogenesis. El-Houjeiri L, Biondini M, Paquette M, Kuasne H, Pacis A, Park M, Siegel PM, Pause A. J Clin Invest. 2021 Nov 15;131(22). pii: 144871. doi: 10.1172/JCI144871. PubMed |
| Follicular lymphoma-associated mutations in the V-ATPase chaperone VMA21 activate autophagy creating a targetable dependency. Wang F, Yang Y, Boudagh G, Eskelinen EL, Klionsky DJ, Malek SN. Autophagy. 2022 Aug;18(8):1982-2000. doi: 10.1080/15548627.2022.2050663. Epub 2022 Mar 24. PubMed |
| Mislocalization of protein kinase A drives pathology in Cushing's syndrome. Omar MH, Byrne DP, Jones KN, Lakey TM, Collins KB, Lee KS, Daly LA, Forbush KA, Lau HT, Golkowski M, McKnight GS, Breault DT, Lefrancois-Martinez AM, Martinez A, Eyers CE, Baird GS, Ong SE, Smith FD, Eyers PA, Scott JD. Cell Rep. 2022 Jul 12;40(2):111073. doi: 10.1016/j.celrep.2022.111073. PubMed |
| Altered-Self MHC Class I Sensing via Functionally Disparate Paired NK Cell Receptors Counters Murine Cytomegalovirus gp34-Mediated Immune Evasion. Cronk JM, Dziewulska KH, Puchalski P, Crittenden RB, Hammarskjold ML, Brown MG. J Immunol. 2022 Oct 15;209(8):1545-1554. doi: 10.4049/jimmunol.2200441. Epub 2022 Sep 7. PubMed |
| Proximity biotinylation to define the local environment of the protein kinase A catalytic subunit in adrenal cells. Omar MH, Lauer SM, Lau HT, Golkowski M, Ong SE, Scott JD. STAR Protoc. 2023 Jan 4;4(1):101992. doi: 10.1016/j.xpro.2022.101992. PubMed |
Compromised nonsense-mediated RNA decay results in truncated RNA-binding protein production upon DUX4 expression.
Campbell AE, Dyle MC, Albanese R, Matheny T, Sudheendran K, Cortazar MA, Forman T, Fu R, Gillen AE, Caruthers MH, Floor SN, Calviello L, Jagannathan S.
Cell Rep. 2023 Jun 13;42(6):112642. doi: 10.1016/j.celrep.2023.112642.
PubMed
Associated Plasmids |
| Hierarchical phosphorylation of HOXB13 by mTOR dictates its activity and oncogenic function in prostate cancer. Chen Y, Dufour CR, Han L, Li T, Xia H, Giguere V. Mol Cancer Res. 2023 Jul 6:MCR-23-0086. doi: 10.1158/1541-7786.MCR-23-0086. PubMed |
| Iron-responsive element of Divalent metal transporter 1 (Dmt1) controls Notch-mediated cell fates. Hounjet J, Groot AJ, Piepers JP, Kranenburg O, Zwijnenburg DA, Rapino FA, Koster JB, Kampen KR, Vooijs MA. FEBS J. 2023 Dec;290(24):5811-5834. doi: 10.1111/febs.16946. Epub 2023 Sep 7. PubMed |
| Recruitment of BAG2 to DNAJ-PKAc scaffolds promotes cell survival and resistance to drug-induced apoptosis in fibrolamellar carcinoma. Lauer SM, Omar MH, Golkowski MG, Kenerson HL, Lee KS, Pascual BC, Lim HC, Forbush K, Smith FD, Gordan JD, Ong SE, Yeung RS, Scott JD. Cell Rep. 2024 Feb 27;43(2):113678. doi: 10.1016/j.celrep.2024.113678. Epub 2024 Jan 17. PubMed |
| Stalled translation by mitochondrial stress upregulates a CNOT4-ZNF598 ribosomal quality control pathway important for tissue homeostasis. Geng J, Li S, Li Y, Wu Z, Bhurtel S, Rimal S, Khan D, Ohja R, Brandman O, Lu B. Nat Commun. 2024 Feb 22;15(1):1637. doi: 10.1038/s41467-024-45525-3. PubMed |
| Inhibition of ULK1/2 and KRAS(G12C) controls tumor growth in preclinical models of lung cancer. Ghazi PC, O'Toole KT, Srinivas Boggaram S, Scherzer MT, Silvis MR, Zhang Y, Bogdan M, Smith BD, Lozano G, Flynn DL, Snyder EL, Kinsey CG, McMahon M. Elife. 2024 Aug 30;13:RP96992. doi: 10.7554/eLife.96992. PubMed |
| Hypoxia Abrogates Tumor-Suppressive Activities of C/EBPdelta in Pancreatic Cancer. Hartl L, Ten Brink MS, Aberson HL, Koster J, Zwijnenburg DA, Duitman J, Bijlsma MF, Spek CA. Int J Mol Sci. 2024 Aug 30;25(17):9449. doi: 10.3390/ijms25179449. PubMed |
| High protection and transmission-blocking immunity elicited by single-cycle SARS-CoV-2 vaccine in hamsters. Lett MJ, Otte F, Hauser D, Schon J, Kipfer ET, Hoffmann D, Halwe NJ, Breithaupt A, Ulrich L, Britzke T, Kochmann J, Corleis B, Zhang Y, Urda L, Cmiljanovic V, Lang C, Beer M, Mittelholzer C, Klimkait T. NPJ Vaccines. 2024 Oct 30;9(1):206. doi: 10.1038/s41541-024-00992-z. PubMed |
Glucose limitation protects cancer cells from apoptosis induced by pyrimidine restriction and replication inhibition.
Nam M, Xia W, Mir AH, Jerrett A, Spinelli JB, Huang TT, Possemato R.
Nat Metab. 2024 Dec;6(12):2338-2353. doi: 10.1038/s42255-024-01166-w. Epub 2024 Nov 26.
PubMed
Associated Plasmids |
| SPT5 regulates RNA polymerase II stability via Cullin 3-ARMC5 recognition. Aoi Y, Iravani L, Mroczek IC, Gold S, Howard BC, Shilatifard A. Sci Adv. 2025 Jan 24;11(4):eadt5885. doi: 10.1126/sciadv.adt5885. Epub 2025 Jan 24. PubMed |
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