We narrowed to 15,020 results for: invs

1. pLentiCRISPR V2 Neo sgAGAP1_2

   Plasmid

   #233247

   Purpose

   Knock out of murine AGAP1

   Depositor

   David Bryant

   Article

   Nikolatou et al EMBO J. 2023 Sep 18;42(18):e113987. doi:

   Insert

   AGAP1 (Agap1 Mouse)
   

   Use

   Lentiviral

   Tags

   Expression

   Mutation

   Promoter

   Available since

   March 11, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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2. pWZL-Blast FAP S624A

   Plasmid

   #207402

   Purpose

   Expresses the S624A mutant of FAP (Fibroblast Activation Protein), which shows no protease activity.

   Depositor

   Jing Yang

   Article

   Bukhari et al Cell Rep. 2023 Oct 31;42(10):113302. doi

   Insert

   Fibroblast Activation Protein Alpha (FAP Human)
   

   Use

   Retroviral

   Tags

   Expression

   Mutation

   changed Serine 624 to Alanine. It's a protea…

   Promoter

   Available since

   Dec. 12, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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3. pWZL-Blast FAP A657S

   Plasmid

   #207403

   Purpose

   Expresses the A657S mutant of FAP (Fibroblast Activation Protein), which shows partial protease activity.

   Depositor

   Jing Yang

   Article

   Bukhari et al Cell Rep. 2023 Oct 31;42(10):113302. doi

   Insert

   Fibroblast Activation Protein Alpha (FAP Human)
   

   Use

   Retroviral

   Tags

   Expression

   Mutation

   changed Alanine 657 to Serine. It's an endop…

   Promoter

   Available since

   Dec. 12, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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4. pUC-hU6-shBACH1_BFP

   Plasmid

   #199217

   Purpose

   Expression plasmid with shRNAmiR targeting BACH1, with a BFP reporter on the backbone. 

   Depositor

   Gabor Balazsi

   Article

   Wan et al Nat Chem Biol. 2023 Jul;19(7):887-899. d

   Insert

   shBACH1 (BACH1 Synthetic)
   

   Use

   RNAi

   Tags

   Expression

   Mutation

   Promoter

   human U6

   Available since

   Aug. 2, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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5. pUC_hU6-shRKIP_BFP

   Plasmid

   #199216

   Purpose

   Expression plasmid with shRNAmiR targeting RKIP (PEBP1), with a BFP reporter on the backbone.

   Depositor

   Gabor Balazsi

   Article

   Wan et al Nat Chem Biol. 2023 Jul;19(7):887-899. d

   Insert

   shBACH1 (BACH1 Synthetic)
   

   Use

   RNAi

   Tags

   Expression

   Mutation

   Promoter

   human U6

   Available since

   June 28, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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6. pCS2plus-TDP-43

   Plasmid

   #162608

   Purpose

   Allows for transcription of TDP-43 mRNA for injection into zebrafish embryos for BiFC assays

   Depositor

   Marco Morsch

   Article

   Don et al Mol Neurobiol. 2021 May;58(5):2061-2074.

   Insert

   TARDBP (TARDBP Human)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   June 10, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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7. MSCV-HA-Nr4a1-Zf2

   Plasmid

   #160944

   Purpose

   Generation of retrovirus for the overexpression of Nr4a1 mutant (zinc finger 2 deletion)

   Depositor

   Matthew Steinhauser

   Article

   Zhang et al J Clin Invest. 2018 Nov 1;128(11):4898-4

   Insert

   Nr4a1 (Nr4a1 Mouse)
   

   Use

   Retroviral

   Tags

   HA tag

   Expression

   Mammalian

   Mutation

   Deletion of Zinc finger 2 (C306 to C330)

   Promoter

   MSCV-LTR

   Available since

   Dec. 11, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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8. MSCV-HA-Nr4a1-Zf1

   Plasmid

   #160943

   Purpose

   Generation of retrovirus for the overexpression of Nr4a1 mutant (zinc finger 1 deletion)

   Depositor

   Matthew Steinhauser

   Article

   Zhang et al J Clin Invest. 2018 Nov 1;128(11):4898-4

   Insert

   Nr4a1 (Nr4a1 Mouse)
   

   Use

   Retroviral

   Tags

   HA tag

   Expression

   Mammalian

   Mutation

   Deletion of Zinc finger 1 (C270 to C290)

   Promoter

   MSCV-LTR

   Available since

   Dec. 10, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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9. pLEX303-GFP-IQSEC1 v2N/v4C-WT

   Plasmid

   #162022

   Purpose

   Expression of IQSEC1 chimera

   Depositor

   David Bryant

   Article

   Nacke et al Nat Commun. 2021 Mar 12;12(1):1623. doi:

   Insert

   IQSEC1 (IQSEC1 Human)
   

   Use

   Lentiviral

   Tags

   Expression

   Mutation

   v2N/v4C

   Promoter

   Available since

   Dec. 7, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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10. pLEX303-GFP-IQSEC1 v4N/v1C-WT

    Plasmid

    #162024

    Purpose

    Expression of IQSEC1 chimera

    Depositor

    David Bryant

    Article

    Nacke et al Nat Commun. 2021 Mar 12;12(1):1623. doi:

    Insert

    IQSEC1 (IQSEC1 Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    v4N/v1C

    Promoter

    Available since

    Dec. 7, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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11. pLEX303-GFP-IQSEC1 v2N/v1C-WT

    Plasmid

    #162023

    Purpose

    Expression of IQSEC1 chimera

    Depositor

    David Bryant

    Article

    Nacke et al Nat Commun. 2021 Mar 12;12(1):1623. doi:

    Insert

    IQSEC1 (IQSEC1 Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    v2N/v1C

    Promoter

    Available since

    Dec. 7, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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12. pCDF1-MCS2-EF1-Puro-RGS7-R44C+V56C

    Plasmid

    #113730

    Purpose

    Express double mutant RGS7- R44C+V65C in mamalian cells

    Depositor

    Yardena Samuels

    Article

    Qutob et al Sci Rep. 2018 Jan 12;8(1):653. doi: 10.1

    Insert

    RGS7 (RGS7 Human)
    

    Use

    Lentiviral

    Tags

    Flag

    Expression

    Mammalian

    Mutation

    R44C and V56C

    Promoter

    CMV

    Available since

    Oct. 10, 2018

    Availability

    Academic Institutions and Nonprofits only

13. pcDNA3-CARD14-L156P

    Plasmid

    #69918

    Purpose

    Expresses mutant FLAG-CARD14 in mammalian cells

    Depositor

    Francesca Capon

    Article

    Berki et al J Invest Dermatol. 2015 Jul 23. doi: 10.

    Insert

    CARD14 isoform 3 (CARD14 Human)
    

    Use

    Tags

    FLAG

    Expression

    Bacterial and Mammalian

    Mutation

    L156P

    Promoter

    CMV

    Available since

    Feb. 2, 2016

    Availability

    Academic Institutions and Nonprofits only

14. pLXSN p200 CUX1

    Plasmid

    #90470

    Purpose

    Retroviral vector expressing human p200 CUX1 with a Myc and HA tag at the N- and C-terminus, respectively

    Depositor

    Alain Nepveu

    Article

    Kedinger et al J Biol Chem. 2009 Oct 2;284(40):27701-11

    Insert

    CUX1 (CUX1 Human)
    

    Use

    Retroviral

    Tags

    Ha and myc

    Expression

    Mammalian

    Mutation

    Promoter

    Moloney murine leukemia virus long terminal repeat

    Available since

    March 29, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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15. pAAV-CAG-FLEX-rc [Jaws-KGC-tdTomato-ER2]

    Plasmid

    #84446

    Purpose

    AAV-mediated expression of Jaws-KGC-tdTomato-ER2 under the CAG promoter, in floxed/reversed (Cre-dependent) manner.

    Depositor

    Edward Boyden

    Article

    Chuong et al Nat Neurosci. 2014 Aug;17(8):1123-9. doi

    Has Service

    AAV1, AAV5, and AAV8

    Insert

    Jaws-KGC-tdTomato-ER2
    

    Use

    AAV

    Tags

    ER2, KGC, and tdTomato

    Expression

    Mammalian

    Mutation

    K200R W214F

    Promoter

    CAG

    Available since

    April 27, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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16. pCS2plus-TDP-43 M337V

    Plasmid

    #162609

    Purpose

    Allows for transcription of mutant TDP-43-M337V mRNA for injection into zebrafish embryos for BiFC assays

    Depositor

    Marco Morsch

    Article

    Don et al Mol Neurobiol. 2021 May;58(5):2061-2074.

    Insert

    TARDBP (TARDBP Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    M337V

    Promoter

    Available since

    June 10, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. AAV-CAG-FLPX-rc [Jaws-KGC-tdTomato-ER2]

    Plasmid

    #195488

    Purpose

    AAV-mediated expression of Jaws-KGC-tdTomato-ER2 under the CAG promoter, in FLPX/reversed (Frt-dependent) manner.

    Depositor

    Edward Boyden

    Article

    Chuong et al Nat Neurosci. 2014 Aug;17(8):1123-9. doi

    Insert

    Jaws-KGC-tdTomato-ER2
    

    Use

    AAV

    Tags

    ER2, KGC, and tdTomato

    Expression

    Mammalian

    Mutation

    K200R W214F

    Promoter

    CAG

    Available since

    June 30, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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18. pcDNA3-MKK1

    Plasmid

    #107973

    Purpose

    expression of MAP Kinase Kinase

    Depositor

    Edwin Krebs

    Article

    Seger et al J Biol Chem. 1994 Oct 14;269(41):25699-7

    Insert

    MKK1 (MAP2K1 Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    See depositor comments below.

    Promoter

    CMV

    Available since

    Feb. 20, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. pAAV-Syn-FLEX-rc [Jaws-KGC-tdTomato-ER2]

    Plasmid

    #153536

    Purpose

    AAV-mediated expression of Jaws-KGC-tdTomato-ER2 under the Syn promoter, in floxed/reversed (Cre-dependent) manner.

    Depositor

    Edward Boyden

    Article

    Chuong et al Nat Neurosci. 2014 Aug;17(8):1123-9. doi

    Insert

    Jaws-KGC-tdTomato-ER2
    

    Use

    AAV

    Tags

    ER2, KGC, and tdTomato

    Expression

    Mammalian

    Mutation

    K200R W214F

    Promoter

    Syn

    Available since

    Feb. 1, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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20. pcDNA3-MKK1K97A

    Plasmid

    #107974

    Purpose

    expression of a dominant negative MAP Kinase Kinase

    Depositor

    Edwin Krebs

    Article

    Seger et al J Biol Chem. 1994 Oct 14;269(41):25699-7

    Insert

    MKK1 K97A (MAP2K1 Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    dominant negative; see Depositor Comments below

    Promoter

    CMV

    Available since

    Jan. 7, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge