We narrowed to 10,156 results for: ada

1. pAAV-EFS-TadA8e-Sauri-U6-Lmna sgRNA

   Plasmid

   #206979

   Purpose

   Expresses SauriABE8e by EFS promoter and sgRNA targeting murine Lmna c.1621T mutation by U6 promoter

   Depositor

   Yuxuan Guo

   Article

   Yang et al J Cell Mol Med. 2024 Feb;28(4):e18145. d

   Insert

   Lmna sgRNA
   

   Use

   AAV; Adenine base editor

   Promoter

   U6

   Available Since

   Feb. 13, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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2. pCSDest-ENTR-MCP-ADAR2-DD(E488Q/T490A)-V5

   Plasmid

   #192714

   Purpose

   Mammalian expression vector containing MS2 coat protein fused to ADAR2 catalytic domain (E488Q/T490A) with V5 tag

   Depositor

   Summer Thyme

   Insert

   MCP-ADAR2-DD(E488Q/T490A)-V5
   

   Tags

   V5

   Expression

   Mammalian

   Mutation

   E488Q/T490A

   Promoter

   CMV

   Available Since

   Nov. 14, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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3. pTwist-ENTR-MCP-ADAR2-DD(E488Q/T490A)-V5

   Plasmid

   #192713

   Purpose

   Gateway entry vector containing MS2 coat protein fused to ADAR2 catalytic domain (E488Q/T490A) with V5 tag

   Depositor

   Summer Thyme

   Insert

   MCP-ADAR2-DD(E488Q/T490A)-V5
   

   Use

   Gateway entry vector

   Tags

   V5

   Mutation

   E488Q/T490A

   Promoter

   None

   Available Since

   Nov. 14, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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4. Prham-M.XbaI-M.EcoRI-M.SalI-p15A-aadA

   Plasmid

   #170767

   Purpose

   Methylase expression vector for 5RM assembly: expresses M.XbaI, M.EcoRI and M.SalI DNA methyltransferases in E. coli

   Depositor

   Ichiro Matsumura

   Article

   Matsumura et al Biotechniques. 2022 May;72(5):185-193. d

   Inserts

   M.XbaI
   M.EcoRI
   M.SalI
   

   Expression

   Bacterial

   Promoter

   rhamnose

   Available Since

   Feb. 22, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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5. Prham-M.XhoI-M.MunI-M.Ocy1ORF8430P-p15A-aadA

   Plasmid

   #170768

   Purpose

   Methylase expression vector for 5RM assembly: expresses M.XhoI, M.MunI (MfeI) and M.Ocy1ORF8430P (SpeI) DNA methyltransferases in E. coli

   Depositor

   Ichiro Matsumura

   Article

   Matsumura et al Biotechniques. 2022 May;72(5):185-193. d

   Inserts

   M.XhoI
   M.MunI
   M.Ocy1ORF8430P
   

   Expression

   Bacterial

   Promoter

   rhamnose

   Available Since

   Feb. 22, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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6. MoClo adapted pUC57-Amp Level 1 position 2

   Plasmid

   #109221

   Purpose

   Non binary level 1 position 2 vector adapted for MoClo modular cloning useful for particle bombardment transformation of plants

   Depositor

   Elena Caro Bernat

   Type

   Empty backbone

   Use

   Synthetic Biology

   Available Since

   Feb. 8, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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7. MoClo adapted pUC57-Amp Level 1 position 6

   Plasmid

   #109225

   Purpose

   Non binary level 1 position 6 vector adapted for MoClo modular cloning useful for particle bombardment transformation of plants

   Depositor

   Elena Caro Bernat

   Type

   Empty backbone

   Use

   Synthetic Biology

   Available Since

   Nov. 16, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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8. MoClo adapted pUC57-Amp Level 1 position 4

   Plasmid

   #109223

   Purpose

   Non binary level 1 position 4 vector adapted for MoClo modular cloning useful for particle bombardment transformation of plants

   Depositor

   Elena Caro Bernat

   Type

   Empty backbone

   Use

   Synthetic Biology

   Available Since

   Oct. 3, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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9. MoClo adapted pUC57-Amp Level 1 position 1

   Plasmid

   #109220

   Purpose

   Non binary level 1 position 1 vector adapted for MoClo modular cloning useful for particle bombardment transformation of plants

   Depositor

   Elena Caro Bernat

   Type

   Empty backbone

   Use

   Synthetic Biology

   Available Since

   Sept. 26, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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10. MoClo adapted pUC57-Amp Level 1 position 5

    Plasmid

    #109224

    Purpose

    Non binary level 1 position 5 vector adapted for MoClo modular cloning useful for particle bombardment transformation of plants

    Depositor

    Elena Caro Bernat

    Type

    Empty backbone

    Use

    Synthetic Biology

    Available Since

    Sept. 26, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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11. MoClo adapted pUC57-Amp Level 1 position 7

    Plasmid

    #113044

    Purpose

    Non binary level 1 position 7 vector adapted for MoClo modular cloning useful for particle bombardment transformation of plants

    Depositor

    Elena Caro Bernat

    Type

    Empty backbone

    Use

    Synthetic Biology

    Available Since

    Sept. 26, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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12. MoClo adapted pUC57-Amp Level 1 position 3

    Plasmid

    #109222

    Purpose

    Non binary level 1 position 3 vector adapted for MoClo modular cloning useful for particle bombardment transformation of plants

    Depositor

    Elena Caro Bernat

    Type

    Empty backbone

    Use

    Synthetic Biology

    Available Since

    Sept. 26, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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13. pDV06_feedback_entry_TagBFP-2A-MCS-2A-mNeonGreen-2A-MCP-ADAR2dd(E488Q)-NES

    Plasmid

    #200402

    Purpose

    Entry vector for closed-loop ADAR-based RNA sensors (DART VADAR). Expresses TagBFP constitutively. Expresses mNeonGreen and MCP-ADAR upon target detection

    Depositor

    James Collins

    Article

    Gayet et al Nat Commun. 2023 Mar 11;14(1):1339. doi:

    Insert

    Closed-loop DART VADAR sensor entry cassette
    

    Use

    Synthetic Biology

    Expression

    Mammalian

    Available Since

    June 30, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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14. pC0054-CMV-dPspCas13b-longlinker-ADAR2DD(E488Q/T375G)

    Plasmid

    #103870

    Purpose

    High specificity version of dPspCas13b-ADAR2DD(E488Q) fusions. T375G mutation in the ADAR deaminase domain confers increased specificity with slightly reduced activity.

    Depositor

    Feng Zhang

    Article

    Cox et al Science. 2017 Oct 25. pii: eaaq0180. doi

    Inserts

    PspCas13b
    huADAR2DD (ADARB1 Human)
    

    Use

    CRISPR

    Tags

    GSGGGGS and HIV NES

    Expression

    Mammalian

    Mutation

    Changed histidne 133 to alanine and histidine 105…

    Available Since

    Dec. 13, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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15. LSM0254 (PB)EF1a-ADAR2-T2A-PuroR-P2A-BFP

    Plasmid

    #233445

    Purpose

    PiggyBac donor plasmid to overexpress a full length ADAR2

    Depositor

    Xiaojing Gao

    Article

    Zhang et al Nat Chem Biol. 2025 Mar 28. doi: 10.1038

    Insert

    ADAR2-T2A-PuroR-P2A-BFP
    

    Expression

    Mammalian

    Mutation

    WT

    Promoter

    EF1a

    Available Since

    April 1, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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16. pDV21_feedback_entry_TagBFP-2A-MCS-2A-NLuc-2A-MCP-ADAR2dd(E488Q)-NES

    Plasmid

    #200403

    Purpose

    Entry vector for closed-loop ADAR-based RNA sensors (DART VADAR). Expresses TagBFP constitutively. Expresses NanoLuc and MCP-ADAR upon target detection

    Depositor

    James Collins

    Article

    Gayet et al Nat Commun. 2023 Mar 11;14(1):1339. doi:

    Insert

    Closed-loop DART VADAR sensor entry cassette
    

    Use

    Synthetic Biology

    Expression

    Mammalian

    Available Since

    June 30, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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17. pAAV-hSyn-ADAR2-2a-Fezf2 sesRNA-2a-tTA2-WPRE

    Plasmid

    #239027

    Purpose

    Expression of ADAR2, sesRNA in mammalian cells with hSyn promoter, with tTA2 as efRNA and ADAR2 overexpression.

    Depositor

    Josh Huang

    Article

    Qian et al Nature. 2022 Oct;610(7933):713-721. doi:

    Insert

    sesRNA for mouse Fezf2 (Fezf2 Mouse)
    

    Use

    AAV

    Expression

    Mammalian

    Promoter

    hSyn

    Available Since

    May 14, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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18. YH001 CMV-TO-tm-GS+XTEN-ADAR2(DD-E396A)-RXR (FLP-IN)

    Plasmid

    #233383

    Purpose

    ER-retained catalytically inactive ADAR2dd (E396A mutation)

    Depositor

    Xiaojing Gao

    Article

    Zhang et al Nat Chem Biol. 2025 Mar 28. doi: 10.1038

    Insert

    TM-ADAR2dd
    

    Expression

    Mammalian

    Mutation

    E396A

    Promoter

    CMV

    Available Since

    April 1, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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19. CIRTS-8: bdefensin 3-TBP6.7-hADAR(299-701)E488Q

    Plasmid

    #132545

    Purpose

    Expresses CIRTS-8 (bdefensin 3-TBP6.7-hADAR(299-701)E488Q) in mammalian cells

    Depositor

    Bryan Dickinson

    Article

    Rauch et al Cell. 2019 Jun 27;178(1):122-134.e12. do

    Insert

    CIRTS-8: bdefensin 3-TBP6.7-hADAR(299-701)E488Q-NLS
    

    Tags

    FLAG tag

    Expression

    Mammalian

    Promoter

    cmv d0

    Available Since

    Sept. 30, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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20. LSM044-2 CMV-TO-CCR7-V2-ADAR2dd(E488Q, T501A) (FLP-IN)

    Plasmid

    #233396

    Purpose

    CCR7-V2-ADAR2dd(E488Q, T501A) with a short 4 amino acid linker and V2 tail

    Depositor

    Xiaojing Gao

    Article

    Zhang et al Nat Chem Biol. 2025 Mar 28. doi: 10.1038

    Insert

    CCR7-ADAR2dd
    

    Expression

    Mammalian

    Mutation

    E488Q, T501A on ADAR2dd

    Promoter

    CMV

    Available Since

    June 13, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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