We narrowed to 3,403 results for: aaas

1. LCV2_AAVS1_sgRNA_4

   Plasmid

   #155090

   Purpose

   lentiviral plasmid expressing Cas9 and gRNA targeting AAVS1 safe harbor locus

   Depositor

   Jason Moffat

   Article

   Aregger et al Nat Metab. 2020 Jun;2(6):499-513. doi: 1

   Insert

   AAVS1_sgRNA_4
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   U6 promoter

   Available Since

   Aug. 7, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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2. pLV-Hyg-Snrnp40-skywarp-CRISPR-resistant

   Plasmid

   #134252

   Purpose

   Lentivector encoding CRISPR-resistant skywarp form of Snrnp40 (missing exon 5)

   Depositor

   Bruce Beutler

   Article

   Zhang et al Nat Immunol. 2019 Oct;20(10):1322-1334.

   Insert

   Snrp40 (Snrnp40 Mouse)
   

   Use

   Lentiviral

   Expression

   Mammalian

   Mutation

   deleted amino acids 179-219, and mutated coding s…

   Promoter

   EF1a

   Available Since

   March 19, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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3. pKLV2-U6(gDmap1 v4)-PGK-Puro-BFP

   Plasmid

   #117143

   Purpose

   Express gRNA vs Dmap1

   Depositor

   Kosuke Yusa

   Article

   Yu et al Stem Cells. 2019 Apr 1. doi: 10.1002/ste

   Insert

   gDmap1 v4 (Dmap1 Synthetic)
   

   Use

   CRISPR and Lentiviral

   Mutation

   Deleted BbsI site within WPRE, modified BFP

   Promoter

   human U6 promoter, mouse PGK promoter

   Available Since

   April 26, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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4. pKLV2-U6(gDmap1 v2)-PGK-Puro-BFP

   Plasmid

   #117141

   Purpose

   Express gRNA vs Dmap1

   Depositor

   Kosuke Yusa

   Article

   Yu et al Stem Cells. 2019 Apr 1. doi: 10.1002/ste

   Insert

   gDmap1 v2 (Dmap1 Synthetic)
   

   Use

   CRISPR and Lentiviral

   Mutation

   Deleted BbsI site within WPRE, modified BFP

   Promoter

   human U6 promoter, mouse PGK promoter

   Available Since

   April 26, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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5. pJEP324-pAAV-FullH1TO-SaCa9sgRNAi(emx1sg1)-CMV-TetR-2A-EGFP-KASH-WPRE-shortPA

   Plasmid

   #113701

   Purpose

   Dox-inducible H1 driven SaCas9 gRNA expression cassette with a gRNA targeting EMX1. Followed by an EFS driven GFP-KASH in a separate reading frame.

   Depositor

   Jonathan Ploski

   Article

   Kumar et al Front Mol Neurosci. 2018 Nov 13;11:413.

   Inserts

   SaCas9 gRNA Cassete
   GFP
   

   Use

   AAV and CRISPR

   Tags

   KASH

   Available Since

   Feb. 14, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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6. pJEP322-pAAV-FullU6TO-SaCa9sgRNAi(emx1-sg1)-CMV-TetR-2A-EGFP-KASH-WPRE-shortPA

   Plasmid

   #113699

   Purpose

   Dox-inducible U6 driven SaCas9 gRNA expression cassette with a gRNA targeting EMX1. Followed by an EFS driven GFP-KASH in a separate reading frame.

   Depositor

   Jonathan Ploski

   Article

   Kumar et al Front Mol Neurosci. 2018 Nov 13;11:413.

   Inserts

   SaCas9 gRNA Cassete
   GFP
   

   Use

   AAV and CRISPR

   Tags

   KASH

   Available Since

   Dec. 11, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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7. pLKO.1-shDnd1-No3

   Plasmid

   #70060

   Purpose

   TRC lentiviral vector for shRNA against mouse Dnd1 #3

   Depositor

   Thomas Tuschl

   Article

   Yamaji et al Nature. 2017 Mar 23;543(7646):568-572. d

   Insert

   Dnd1 (Dnd1 Mouse)
   

   Use

   Lentiviral

   Expression

   Mammalian

   Promoter

   EF1alpha

   Available Since

   Nov. 22, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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8. pLKO.1-shDnd1-No4

   Plasmid

   #70065

   Purpose

   TRC lentiviral vector for shRNA against mouse Dnd1 #4

   Depositor

   Thomas Tuschl

   Article

   Yamaji et al Nature. 2017 Mar 23;543(7646):568-572. d

   Insert

   Dnd1 (Dnd1 Mouse)
   

   Use

   Lentiviral

   Expression

   Mammalian

   Promoter

   EF1alpha

   Available Since

   Nov. 22, 2017

   Availability

   Academic Institutions and Nonprofits only

9. pLKO.1-shDnd1-No6

   Plasmid

   #70067

   Purpose

   TRC lentiviral vector for shRNA against mouse Dnd1 #6

   Depositor

   Thomas Tuschl

   Article

   Yamaji et al Nature. 2017 Mar 23;543(7646):568-572. d

   Insert

   Dnd1 (Dnd1 Mouse)
   

   Use

   Lentiviral

   Expression

   Mammalian

   Promoter

   EF1alpha

   Available Since

   Nov. 22, 2017

   Availability

   Academic Institutions and Nonprofits only

10. pDONR223_PPP2R1A_p.W140C

    Plasmid

    #82784

    Purpose

    Gateway Donor vector containing PPP2R1A , part of the Target Accelerator Plasmid Collection.

    Depositor

    Jesse Boehm, Matthew Meyerson, David Root

    Article

    Berger et al Cancer Cell. 2016 Aug 8;30(2):214-28. do

    Insert

    PPP2R1A (PPP2R1A Human)
    

    Use

    Gateway entry vector

    Mutation

    W140C

    Promoter

    None

    Available Since

    April 24, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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11. pDONR223_PPP2R1A_p.A541G

    Plasmid

    #82771

    Purpose

    Gateway Donor vector containing PPP2R1A , part of the Target Accelerator Plasmid Collection.

    Depositor

    Jesse Boehm, Matthew Meyerson, David Root

    Article

    Berger et al Cancer Cell. 2016 Aug 8;30(2):214-28. do

    Insert

    PPP2R1A (PPP2R1A Human)
    

    Use

    Gateway entry vector

    Mutation

    A541G

    Promoter

    None

    Available Since

    April 24, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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12. pDONR223_PPP2R1A_p.S143F

    Plasmid

    #81440

    Purpose

    Gateway Donor vector containing PPP2R1A , part of the Target Accelerator Plasmid Collection.

    Depositor

    Jesse Boehm, William Hahn, David Root

    Article

    Kim et al Cancer Discov. 2016 Jul;6(7):714-26. doi

    Insert

    PPP2R1A (PPP2R1A Human)
    

    Use

    Gateway entry vector

    Mutation

    S143F

    Promoter

    None

    Available Since

    April 24, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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13. pSico shMAP3K2 mouse

    Plasmid

    #85657

    Purpose

    expression of shRNA targeting mouse MAP3K2

    Depositor

    Julien Sage

    Article

    Mazur et al Nature. 2014 Jun 12;510(7504):283-7. doi

    Insert

    shRNA targeting 3'UTR of Map3k2 (Map3k2 Mouse)
    

    Use

    Lentiviral and RNAi

    Expression

    Mammalian

    Promoter

    U6

    Available Since

    Feb. 2, 2017

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. pSico shMAP3K2 human

    Plasmid

    #85656

    Purpose

    expression of shRNA targeting human MAP3K2

    Depositor

    Julien Sage

    Article

    Mazur et al Nature. 2014 Jun 12;510(7504):283-7. doi

    Insert

    shRNA targeting 3'UTR of MAP3K2 (MAP3K2 Human)
    

    Use

    Lentiviral and RNAi

    Expression

    Mammalian

    Promoter

    U6

    Available Since

    Jan. 27, 2017

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. CAMK2B gRNA (BRDN0001148102)

    Plasmid

    #77742

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human CAMK2B

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    CAMK2B (CAMK2B Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 14, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. AURKA gRNA (BRDN0001145351)

    Plasmid

    #77728

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human AURKA

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    AURKA (AURKA Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 13, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. C17orf75 gRNA (BRDN0001145175)

    Plasmid

    #78077

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human C17orf75

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    C17orf75 (C17orf75 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. FASTKD3 gRNA (BRDN0001146235)

    Plasmid

    #78064

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human FASTKD3

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    FASTKD3 (FASTKD3 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. TRIO gRNA (BRDN0001148044)

    Plasmid

    #78032

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human TRIO

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    TRIO (TRIO Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. DGKH gRNA (BRDN0001487100)

    Plasmid

    #78044

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human DGKH

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    DGKH (DGKH Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge