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Plasmid#98355PurposeLentiviral expression of MAP2K3DepositorInsertMAP2K3 (MAP2K3 Human)
UseLentiviralTagsV5ExpressionMammalianMutationQ85KPromoterE1FaAvailable sinceAug. 24, 2017AvailabilityAcademic Institutions and Nonprofits only -
LIC4B-His-TEV-TAK1-TAB1
Plasmid#154874PurposeInsect cell optimized TAK1-TAB1 construct used to solve structure and deposit PDB ID: 4O91DepositorInsertTAK1-TAB1 (TAB1 Human)
UseTagsLIC TEV HisExpressionInsectMutationCodon optimizedPromoterpolyhedrinAvailable sinceOct. 13, 2020AvailabilityAcademic Institutions and Nonprofits only -
MAPK11 gRNA (BRDN0001147606)
Plasmid#77482Purpose3rd generation lentiviral gRNA plasmid targeting human MAPK11DepositorInsertMAPK11 (MAPK11 Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
MAPK11 gRNA (BRDN0001146070)
Plasmid#77483Purpose3rd generation lentiviral gRNA plasmid targeting human MAPK11DepositorInsertMAPK11 (MAPK11 Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
MK08_HUMAN_D0
Plasmid#79695PurposeThis plasmid encodes the kinase domain of MK08. Intended for co-expression with Lambda Phosphatase that accompanies this set to enhance bacterial kinase expression.DepositorInsertMK08 (MAPK8 Human)
UseTagsHis10-TEVExpressionBacterialMutationPromoterT7Available sinceNov. 21, 2016AvailabilityAcademic Institutions and Nonprofits only -
MAPK12 gRNA (BRDN0001146907)
Plasmid#77485Purpose3rd generation lentiviral gRNA plasmid targeting human MAPK12DepositorInsertMAPK12 (MAPK12 Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
MAPK12 gRNA (BRDN0001148543)
Plasmid#77486Purpose3rd generation lentiviral gRNA plasmid targeting human MAPK12DepositorInsertMAPK12 (MAPK12 Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
MAPK12 gRNA (BRDN0001147863)
Plasmid#77487Purpose3rd generation lentiviral gRNA plasmid targeting human MAPK12DepositorInsertMAPK12 (MAPK12 Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
MAP2K3 gRNA (BRDN0001147239)
Plasmid#76381Purpose3rd generation lentiviral gRNA plasmid targeting human MAP2K3DepositorInsertMAP2K3 (MAP2K3 Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
MAPK10 gRNA (BRDN0001148192)
Plasmid#75981Purpose3rd generation lentiviral gRNA plasmid targeting human MAPK10DepositorInsertMAPK10 (MAPK10 Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
MAP2K7 gRNA (BRDN0001149362)
Plasmid#77820Purpose3rd generation lentiviral gRNA plasmid targeting human MAP2K7DepositorInsertMAP2K7 (MAP2K7 Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
MAP2K7 gRNA (BRDN0001162319)
Plasmid#77821Purpose3rd generation lentiviral gRNA plasmid targeting human MAP2K7DepositorInsertMAP2K7 (MAP2K7 Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
MAP2K7 gRNA (BRDN0001149491)
Plasmid#77822Purpose3rd generation lentiviral gRNA plasmid targeting human MAP2K7DepositorInsertMAP2K7 (MAP2K7 Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
MAP2K7 gRNA (BRDN0001162371)
Plasmid#77823Purpose3rd generation lentiviral gRNA plasmid targeting human MAP2K7DepositorInsertMAP2K7 (MAP2K7 Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
pCSmEn2n4ERT(#234)
Plasmid#184082Purposecyclofen-inducible chicken EN2 (mut) activation via mammalian cell transfection or mRNA synthesisDepositorInsert6his-myc-chkEn2(n4)-ERT2
UseSynthetic BiologyTags6his-MycExpressionMammalianMutationchkEn2: G238S; ERT2: G400V, M543A, L544A, deleted…PromotersCMV+SP6Available sinceJune 28, 2022AvailabilityAcademic Institutions and Nonprofits only -
pCSmEn2SRERT(#231)
Plasmid#184080Purposecyclofen-inducible chicken EN2 (mut) activation via mammalian cell transfection or mRNA synthesisDepositorInsert6his-myc-chkEn2(SR)-ERT2
UseSynthetic BiologyTags6his-MycExpressionMammalianMutationchkEn2: W247S, F248R; ERT2: G400V, M543A, L544A, …PromotersCMV+SP6Available sinceJune 28, 2022AvailabilityAcademic Institutions and Nonprofits only -
pT22gCfpUbm5En2E4PCh(#251)
Plasmid#184083Purposecyclofen-inducible chicken EN2 (wt) activation in zebrafish permanent transgenicDepositorInsert5myc-chkEn2-ERT2-P2A-mCherry
UseZebrafish transgenesis (blue eyes)Tags5xMycExpressionMutationERT2: G400V, M543A, L544A, deleted 1-281;PromoterZf-UbiAvailable sinceJune 9, 2022AvailabilityAcademic Institutions and Nonprofits only -
pT22Ubm5Eng2bE4PCh(#284)
Plasmid#184088Purposecyclofen-inducible fish Eng2b (wt) activation in zebrafish permanent transgenicDepositorInsert5myc-ZfEng2b-ERT2-P2A-mCherry
UseZebrafish transgenesis (blue eyes)Tags5xMycExpressionMutationERT2: G400V, M543A, L544A, deleted 1-281;PromoterZf-UbiAvailable sinceJune 9, 2022AvailabilityAcademic Institutions and Nonprofits only -
pT22Ubm5Eng2aE4PCh(#283)
Plasmid#184087Purposecyclofen-inducible fish Eng2a (wt) activation in zebrafish permanent transgenicDepositorInsert5myc-ZfEng2a-ERT2-P2A-mCherry
UseZebrafish transgenesis (blue eyes)Tags5xMycExpressionMutationERT2: G400V, M543A, L544A, deleted 1-281;PromoterZf-UbiAvailable sinceJune 9, 2022AvailabilityAcademic Institutions and Nonprofits only -
pCSmEn25EERT(#232)
Plasmid#184081Purposecyclofen-inducible chicken EN2 (mut) activation via mammalian cell transfection or mRNA synthesisDepositorInsert6his-myc-chkEn2(5E)-ERT2
UseSynthetic BiologyTags6his-MycExpressionMammalianMutationchkEn2: S150E, S151E, S153E, S155E, S156E; ERT2: …PromotersCMV+SP6Available sinceJune 9, 2022AvailabilityAcademic Institutions and Nonprofits only -
MAPK11 gRNA (BRDN0001147839)
Plasmid#77484Purpose3rd generation lentiviral gRNA plasmid targeting human MAPK11DepositorInsertMAPK11 (MAPK11 Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
DLG1 gRNA (BRDN0001148200)
Plasmid#76617Purpose3rd generation lentiviral gRNA plasmid targeting human DLG1DepositorInsertDLG1 (DLG1 Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
DLG1 gRNA (BRDN0001148018)
Plasmid#76618Purpose3rd generation lentiviral gRNA plasmid targeting human DLG1DepositorInsertDLG1 (DLG1 Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
DLG1 gRNA (BRDN0001145356)
Plasmid#76619Purpose3rd generation lentiviral gRNA plasmid targeting human DLG1DepositorInsertDLG1 (DLG1 Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
MAP2K6 gRNA (BRDN0001145878)
Plasmid#76039Purpose3rd generation lentiviral gRNA plasmid targeting human MAP2K6DepositorInsertMAP2K6 (MAP2K6 Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
MAP2K6 gRNA (BRDN0001145312)
Plasmid#76040Purpose3rd generation lentiviral gRNA plasmid targeting human MAP2K6DepositorInsertMAP2K6 (MAP2K6 Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
MAP2K6 gRNA (BRDN0001147036)
Plasmid#76041Purpose3rd generation lentiviral gRNA plasmid targeting human MAP2K6DepositorInsertMAP2K6 (MAP2K6 Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
MAPK10 gRNA (BRDN0001146535)
Plasmid#75982Purpose3rd generation lentiviral gRNA plasmid targeting human MAPK10DepositorInsertMAPK10 (MAPK10 Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
MAPK10 gRNA (BRDN0001148098)
Plasmid#75983Purpose3rd generation lentiviral gRNA plasmid targeting human MAPK10DepositorInsertMAPK10 (MAPK10 Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
DLG1 gRNA (BRDN0001147622)
Plasmid#76620Purpose3rd generation lentiviral gRNA plasmid targeting human DLG1DepositorInsertDLG1 (DLG1 Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJune 27, 2016AvailabilityAcademic Institutions and Nonprofits only -
pCDFDuet-MKK6-EE p38alpha
Plasmid#82719PurposeExpresses constitutively active human MKK6 and murine p38 alpha.DepositorUseTagsExpressionBacterialMutationSer207 to Glu, Thr211 to GluPromoterAvailable sinceFeb. 28, 2019AvailabilityAcademic Institutions and Nonprofits only -
pCDNA3 Flag MKK7B2Jnk1a1
Plasmid#19726DepositorUseTagsFlagExpressionMammalianMutationPromoterAvailable sinceMarch 24, 2009AvailabilityAcademic Institutions and Nonprofits only -
pDEST-Tol2-PA2-CMV-AB-mCh
Plasmid#160435PurposeExpresses human Amyloid Beta-mCherry in ZebrafishDepositorInsertHuman Amyloid Beta peptide (1-42) (APP Zebrafish, Human)
UseZebrafish expressionTagsmCherryExpressionMutationPromoterCMVAvailable sinceOct. 6, 2021AvailabilityAcademic Institutions and Nonprofits only -
tetO-HEY2
Plasmid#170691Purposedoxycycline-inducible overexpression of HEY2DepositorInsertHEY2 – hes related family bHLH transcription factor with YRPW motif 2 (HEY2 Human)
UseLentiviral; Doxycycline inducibleTagsExpressionMammalianMutationPromoterTRE promoter, Tet-ONAvailable sinceJuly 12, 2023AvailabilityAcademic Institutions and Nonprofits only -
pCDNA3 Flag MKK7B2Jnk3a2
Plasmid#19729DepositorUseTagsFlagExpressionMammalianMutationPromoterAvailable sinceMarch 31, 2009AvailabilityAcademic Institutions and Nonprofits only -
MAP2K4 gRNA (BRDN0001145028)
Plasmid#76650Purpose3rd generation lentiviral gRNA plasmid targeting human MAP2K4DepositorInsertMAP2K4 (MAP2K4 Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
pGBdest-GST-PI3Kc1
Plasmid#187992PurposePlasmid for the protein expression of GST-3C-ATG14/Vps34/Vps15/BECN1 in a bacterial and insect expression system. Internal_Reference: SMC1326DepositorUseTagsGSTExpressionBacterial and InsectMutationPromoterAvailable sinceFeb. 7, 2023AvailabilityAcademic Institutions and Nonprofits only -
pCDNA3 Flag Jnk1a1MKK7B2
Plasmid#19731DepositorUseTagsFlagExpressionMammalianMutationPromoterAvailable sinceMarch 24, 2009AvailabilityAcademic Institutions and Nonprofits only -
MIGR1-Cdc42-1
Plasmid#179517PurposeRetroviral expression of Cdc42 splice variant 1DepositorInsertCdc42 splice variant 1 cDNA (CDC42 Human)
UseRetroviralTagsIRES-EGFPExpressionMutationPromoterLTRAvailable sinceApril 29, 2022AvailabilityAcademic Institutions and Nonprofits only -
pHAGE-MAP2K4
Plasmid#116758PurposeLentiviral expression of MAP2K4DepositorInsertMAP2K4 (MAP2K4 Human)
UseLentiviralTagsExpressionMutationWTPromoterAvailable sinceMarch 14, 2019AvailabilityAcademic Institutions and Nonprofits only