We narrowed to 22,001 results for: Sis

1. pFS_0350_pET30-RT-CRISPR_Cellulomonas_bogoriensis_69B4_ARRAY_1_RC

   Plasmid

   #116962

   Purpose

   Expresses CbRT-Cas1-Cas2 under pT7lac promoter, encodes CbCRISPR array 1 RC, compatible with SENECA acquisition readout

   Depositor

   Randall Platt

   Article

   Schmidt et al Nature. 2018 Oct;562(7727):380-385. doi:

   Insert

   Cellulomonas bogoriensis 69B4 RT-Cas1-Cas2
   

   Use

   Tags

   Expression

   Bacterial

   Mutation

   Promoter

   T7

   Available since

   Nov. 2, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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2. pmCherry_C1 I3(resist)

   Plasmid

   #61399

   Purpose

   Expresses mCherry tagged Inhibitor-3 resistant to I3 S2 siRNA in mammalian cells

   Depositor

   Hemmo Meyer

   Article

   Eiteneuer et al EMBO J. 2014 Oct 8. pii: e201489054.

   Insert

   Inhibitor-3 (PPP1R11 Human)
   

   Use

   Tags

   mCherry

   Expression

   Mammalian

   Mutation

   silent mutations of bases C183T T192C T189C

   Promoter

   CMV

   Available since

   Sept. 25, 2015

   Availability

   Academic Institutions and Nonprofits only

3. DHFR Saturation Mutagenesis Library - WT TYMS

   Pooled Library

   #1000000194

   Depositor

   Kimberly Reynolds

   Available since

   May 8, 2024

   Availability

   Academic Institutions and Nonprofits only

4. hCRISPRa-v2, Cancer and Apoptosis (h2), top 5 sgRNAs/gene

   Pooled Library

   #83981

   Purpose

   Human CRISPRa Pooled Library targeting cancer and apoptosis genes

   Depositor

   Jonathan Weissman

   Article

   Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

   Available since

   Jan. 12, 2017

   Availability

   Academic Institutions and Nonprofits only

5. mCRISPRi-v2, Stress and Proteostasis (m3), top 5 sgRNAs/gene

   Pooled Library

   #83991

   Purpose

   Mouse CRISPRi Pooled Library targeting stress and proteostasis genes

   Depositor

   Jonathan Weissman

   Article

   Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

   Available since

   Jan. 12, 2017

   Availability

   Academic Institutions and Nonprofits only

6. mCRISPRi-v2, Cancer and Apoptosis (m2), top 5 sgRNAs/gene

   Pooled Library

   #83990

   Purpose

   Mouse CRISPRi Pooled Library targeting cancer and apoptosis genes

   Depositor

   Jonathan Weissman

   Article

   Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

   Available since

   Jan. 12, 2017

   Availability

   Academic Institutions and Nonprofits only

7. mCRISPRa-v2, Cancer and Apoptosis (m2), top 5 sgRNAs/gene

   Pooled Library

   #83999

   Purpose

   Mouse CRISPRa Pooled Library targeting cancer and apoptosis genes

   Depositor

   Jonathan Weissman

   Article

   Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

   Available since

   Jan. 12, 2017

   Availability

   Academic Institutions and Nonprofits only

8. hCRISPRa-v2, Stress and Proteostasis (h3), top 5 sgRNAs/gene

   Pooled Library

   #83982

   Purpose

   Human CRISPRa Pooled Library targeting stress and proteostasis genes

   Depositor

   Jonathan Weissman

   Article

   Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

   Available since

   Jan. 12, 2017

   Availability

   Academic Institutions and Nonprofits only

9. mCRISPRa-v2, Stress and Proteostasis (m3), top 5 sgRNAs/gene

   Pooled Library

   #84000

   Purpose

   Mouse CRISPRi Pooled Library targeting stress and proteostasis genes

   Depositor

   Jonathan Weissman

   Article

   Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

   Available since

   Jan. 12, 2017

   Availability

   Academic Institutions and Nonprofits only

10. hCRISPRi-v2, Cancer and Apoptosis (h2), top 5 sgRNAs/gene

    Pooled Library

    #83972

    Purpose

    Human CRISPRi Pooled Library targeting cancer and apoptosis genes

    Depositor

    Jonathan Weissman

    Article

    Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

    Available since

    Dec. 14, 2016

    Availability

    Academic Institutions and Nonprofits only

11. pCMV-Rep78/68 Scanning Saturation Mutagenesis (SSM)

    Pooled Library

    #198050

    Purpose

    By supplying an AAV cap gene of interest in trans, researchers can use this library to investigate the effects of rep mutations on production of a wide range of AAV capsid serotypes

    Depositor

    George Church

    Article

    Jain et al bioRxiv 2023.01.31.526541

    Expression

    Mammalian

    Use

    AAV

    Available since

    May 4, 2023

    Availability

    Academic Institutions and Nonprofits only

12. hCRISPRi-v2, Stress and Proteostasis (h3), top 5 sgRNAs/gene

    Pooled Library

    #83973

    Purpose

    Human CRISPRi Pooled Library targeting stress and proteostasis genes

    Depositor

    Jonathan Weissman

    Article

    Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

    Available since

    Dec. 14, 2016

    Availability

    Academic Institutions and Nonprofits only

13. DHFR Saturation Mutagenesis Library - Q33S TYMS

    Pooled Library

    #1000000196

    Depositor

    Kimberly Reynolds

    Available since

    May 8, 2024

    Availability

    Academic Institutions and Nonprofits only

14. DHFR Saturation Mutagenesis Library - R166Q TYMS

    Pooled Library

    #1000000195

    Depositor

    Kimberly Reynolds

    Available since

    May 8, 2024

    Availability

    Academic Institutions and Nonprofits only

15. pEXSISERS_mGreenLantern_FRT-PuroR-HSV-TK

    Plasmid

    #177868

    Purpose

    Cloning Backbone for mGreenLantern-based EXSISERS containing FRT-sites flanked PuroR-HSV-TK cassette; clone homology arms via BbsI (or BpiI).

    Depositor

    Gil Westmeyer

    Article

    Truong et al Nat Cell Biol. 2021 Jun;23(6):652-663. d

    Insert

    mGreenLantern-based EXSISERS
    

    Use

    CRISPR, Synthetic Biology, and Unspecified

    Tags

    OLLAS

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    April 8, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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16. hHSF1 RNAi resistant

    Plasmid

    #118347

    Purpose

    This plasmid expresses RNAi resistance version of hHSF1 to use for rescue experiments with HSF1 shRNA vector (plasmid #118345).

    Depositor

    Lea Sistonen

    Article

    Ostling et al J Biol Chem. 2007 Mar 9;282(10):7077-86.

    Insert

    hHSF1 (HSF1 Human)
    

    Use

    Tags

    myc and 6xHIS

    Expression

    Mammalian

    Mutation

    RNAi resistance mutations (does not change amino …

    Promoter

    Available since

    Nov. 8, 2018

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. pET-SisTnpB1–ωRNA

    Plasmid

    #228365

    Purpose

    Expresses SisTnpB1 and RNP complex in E. coli Rosetta (DE3) cells

    Depositor

    Tao Liu

    Article

    Xu et al Commun Biol. 2024 Nov 20;7(1):1541. doi:

    Insert

    SisTnpB1
    

    Use

    Tags

    Expression

    Bacterial

    Mutation

    Promoter

    T7

    Available since

    Feb. 7, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. BAP1-wt (siRNA resistant)

    Plasmid

    #108439

    Purpose

    Stable expression of BAP1-wt in mammalian cells, gene has an introduced siRNA-resistance against siBAP1.

    Depositor

    Rolf Stahel, Emanuela Felley-Bosco

    Article

    Okonska et al Mol Cancer Ther. 2019 Oct 16. pii: 1535-

    Insert

    BAP1 (BAP1 Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    c.1641C>T, c.1644T>A, c.1647T>C, c.1650C…

    Promoter

    CMV

    Available since

    Nov. 22, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. pRG705_lexO-AsiSI_LexA-TF_LEU2MX

    Plasmid

    #154817

    Purpose

    Inducible expression of AsiSI endonuclease in S. cerevisiae

    Depositor

    Lorraine Symington

    Article

    Gnugge et al Nucleic Acids Res. 2020 Oct 14. pii: 592

    Inserts

    AsiSI endonuclease
    LexA-ER-B112
    

    Use

    Tags

    FLAG and NLS

    Expression

    Yeast

    Mutation

    Promoter

    ACT1 and lexO_4-CYC1_core

    Available since

    Oct. 26, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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20. pcDNA3.2-Cx43-siResist

    Plasmid

    #49852

    Purpose

    Encodes human connexin 43 with wobble mutations conferring resistance against an siRNA

    Depositor

    Robin Shaw

    Article

    Smyth et al Cell Rep. 2013 Nov 5. pii: S2211-1247(13

    Insert

    Connexin 43 (GJA1 Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Contains several wobble mutations to confer resis…

    Promoter

    CMV

    Available since

    Jan. 17, 2014

    Availability

    Academic Institutions and Nonprofits only