We narrowed to 6,115 results for: arl

1. MKC91_tEPOR(UbC-GFP-BGH)

   Plasmid

   #232406

   Purpose

   AAV production plasmid for tEPOR-UbC-GFP-BGH vector from Fig. 1 that mediates HDR at EPOR locus using EPOR-sg1 gRNA. Repair vector introduces premature stop codon into EPOR locus.

   Depositor

   Kyle Cromer, Matthew Porteus

   Article

   Luna et al Nat Biomed Eng. 2024 Dec;8(12):1540-1552

   Insert

   Truncated Erythropoietin Receptor (EPOR Human)
   

   Use

   AAV

   Expression

   Mammalian

   Available Since

   Feb. 26, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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2. HEK4-53bp-tag-insertion-pegRNA

   Plasmid

   #227673

   Purpose

   PegRNA for 53 bp insertion

   Depositor

   Scot Wolfe

   Article

   Liu et al Nat Biotechnol. 2024 Sep 25. doi: 10.103

   Insert

   SpCas9 sgRNA scaffold (EPHA3 Human)
   

   Use

   CRISPR

   Expression

   Mammalian

   Promoter

   U6

   Available Since

   Oct. 22, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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3. Tet-O-FUW-CSRNP2-P2A-mCherry

   Plasmid

   #203867

   Purpose

   Tet-inducible lentiviral plasmid expressing CSRNP2-P2A-mCherry, with ORF specific barcode close to 3'LTR site

   Depositor

   Andrea Califano

   Article

   Obradovic et al Cancer Cell. 2023 May 8;41(5):933-949.e1

   Insert

   CSRNP2 (CSRNP2 Human)
   

   Expression

   Mammalian

   Available Since

   Aug. 2, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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4. pLKO.1-puro-shRPS6

   Plasmid

   #125780

   Purpose

   constitutive expression of a short-hairpin RNA targeting human RPS6 (RNAi positive control)

   Depositor

   Francisca Vazquez

   Article

   Chan et al Nature. 2019 Apr 10. pii: 10.1038/s41586

   Insert

   shRPS6 (RPS6 Human)
   

   Use

   RNAi

   Available Since

   June 4, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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5. pXPR_BRD003-sgCh2-2

   Plasmid

   #125767

   Purpose

   constitutive expression of a guide RNA targeting an intergenic region of human chromosome 2 (CRISPR cutting control)

   Depositor

   Francisca Vazquez

   Article

   Chan et al Nature. 2019 Apr 10. pii: 10.1038/s41586

   Insert

   sgCh2-2
   

   Use

   CRISPR

   Available Since

   June 4, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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6. pXPR_BRD003-sgCh2-4

   Plasmid

   #125768

   Purpose

   constitutive expression of a guide RNA targeting an intergenic region of human chromosome 2 (CRISPR cutting control)

   Depositor

   Francisca Vazquez

   Article

   Chan et al Nature. 2019 Apr 10. pii: 10.1038/s41586

   Insert

   sgCh2-4
   

   Use

   CRISPR

   Available Since

   June 4, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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7. pLVE-FH-Dnd1-IN

   Plasmid

   #70072

   Purpose

   2nd gen lentiviral vector. Cre-removable and tet/dox-controllable expression of FLAG-HA-tagged murine Dnd1 in mammalian cells.

   Depositor

   Thomas Tuschl

   Article

   Yamaji et al Nature. 2017 Mar 23;543(7646):568-572. d

   Insert

   Dnd1 (Dnd1 Mouse)
   

   Use

   Cre/Lox and Lentiviral

   Tags

   FLAG and HA

   Expression

   Mammalian

   Promoter

   EF1alpha

   Available Since

   Nov. 22, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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8. pAav-TP53-PQS1-3xFLAG

   Plasmid

   #84884

   Purpose

   rAAV-based template for genome engineering of the p53 C-terminus containing PQS1 and 3xFLAG tags and a selection cassette

   Depositor

   Sven Eyckerman

   Article

   Vandemoortele et al Sci Rep. 2016 Jun 6;6:27220. doi: 10.103

   Inserts

   TP53 genomic region HR1 (TP53 Human)
   TP53 genomic region HR2
   

   Use

   AAV

   Tags

   PQS1 3xFLAG

   Promoter

   no and no

   Available Since

   Nov. 28, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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9. im:7163548_L (OZ571)

   Plasmid

   #35211

   Depositor

   Keith Joung

   Article

   Maeder et al Mol Cell. 2008 Jul 25. 31(2):294-301.

   Insert

   Zinc finger array targeting im:7163548 (im:7163548 Zebrafish)
   

   Use

   Zebrafish targeting

   Available Since

   March 16, 2012

   Availability

   Academic Institutions and Nonprofits only

10. zgc:162148_L (OZ579)

    Plasmid

    #35219

    Depositor

    Keith Joung

    Article

    Maeder et al Mol Cell. 2008 Jul 25. 31(2):294-301.

    Insert

    Zinc finger array targeting zgc:162148 (micu1 Zebrafish)
    

    Use

    Zebrafish targeting

    Available Since

    March 15, 2012

    Availability

    Academic Institutions and Nonprofits only

11. im:7163548_R (OZ572)

    Plasmid

    #35212

    Depositor

    Keith Joung

    Article

    Maeder et al Mol Cell. 2008 Jul 25. 31(2):294-301.

    Insert

    Zinc finger array targeting im:7163548 (im:7163548 Zebrafish)
    

    Use

    Zebrafish targeting

    Available Since

    March 15, 2012

    Availability

    Academic Institutions and Nonprofits only

12. pLX209-neo-active WRN

    Plasmid

    #125788

    Purpose

    constitutive, ectopic expression of human active WRN

    Depositor

    Francisca Vazquez

    Article

    Chan et al Nature. 2019 Apr 10. pii: 10.1038/s41586

    Insert

    myc-active WRN (WRN Human)
    

    Tags

    5x myc

    Expression

    Mammalian

    Available Since

    June 4, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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13. pAAV_CaMKIIa(0.4)-PdCO-EGFP-WPRE

    Plasmid

    #198514

    Purpose

    Expresses optimized PdCO in frame with EGFP under control of minimal CamKIIa promotor.

    Depositor

    Ofer Yizhar

    Article

    Wietek et al Nat Methods. 2024 May 29. doi: 10.1038/s

    Insert

    PdCO
    

    Use

    AAV

    Tags

    EGFP and Rho1D4

    Expression

    Mammalian

    Promoter

    CaMKIIα minimal promotor (0.4kb)

    Available Since

    July 5, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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14. pRK5-EGFP-Tau E14

    Plasmid

    #46907

    Purpose

    expresses EGFP tagged Tau E14 in mammalian cells

    Depositor

    Karen Ashe

    Article

    Hoover et al Neuron. 2010 Dec 22;68(6):1067-81. doi:

    Insert

    Tau E14 (MAPT Human)
    

    Tags

    EGFP

    Expression

    Mammalian

    Mutation

    all 14 S/P or T/P amino acid residues (T111, T153…

    Promoter

    CMV

    Available Since

    July 24, 2013

    Availability

    Academic Institutions and Nonprofits only

    

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15. pGEX-4T1 human PP2A Aα full length

    Plasmid

    #132634

    Purpose

    expresses human PP2A Aα full length in E. coli

    Depositor

    Wenqing Xu

    Article

    Sangodkar et al J Clin Invest. 2017 Jun 1;127(6):2081-20

    Insert

    PP2A Aα (PPP2R1A Human)
    

    Expression

    Bacterial

    Available Since

    Oct. 17, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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16. pRK5-EGFP-Tau E14 P301L

    Plasmid

    #46909

    Purpose

    expresses EGFP tagged Tau E14 P301L in mammalian cells

    Depositor

    Karen Ashe

    Article

    Hoover et al Neuron. 2010 Dec 22;68(6):1067-81. doi:

    Insert

    Tau E14 P301L (MAPT Human)
    

    Tags

    EGFP

    Expression

    Mammalian

    Mutation

    P301L AND all 14 S/P or T/P amino acid residues (…

    Promoter

    CMV

    Available Since

    July 24, 2013

    Availability

    Academic Institutions and Nonprofits only

    

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17. pRK5-EGFP-Tau AP P301L

    Plasmid

    #46906

    Purpose

    expresses EGFP tagged Tau AP P301L in mammalian cells

    Depositor

    Karen Ashe

    Article

    Hoover et al Neuron. 2010 Dec 22;68(6):1067-81. doi:

    Insert

    Tau AP P301L (MAPT Human)
    

    Tags

    EGFP

    Expression

    Mammalian

    Mutation

    P301L AND all 14 S/P or T/P amino acid residues (…

    Promoter

    CMV

    Available Since

    July 24, 2013

    Availability

    Academic Institutions and Nonprofits only

    

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18. pLX209-neo-WRN K577M

    Plasmid

    #125790

    Purpose

    constitutive, ectopic expression of a helicase-dead mutant of human WRN (K577M)

    Depositor

    Francisca Vazquez

    Article

    Chan et al Nature. 2019 Apr 10. pii: 10.1038/s41586

    Insert

    myc-WRN K577M (WRN Human)
    

    Tags

    5x myc

    Expression

    Mammalian

    Mutation

    K577M (helicase-dead)

    Available Since

    June 27, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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19. pET_His6-SUMO-TEV-TtCsm6

    Plasmid

    #172486

    Purpose

    Bacterial expression of codon-optimized His-SUMO-TtCsm6 with a TEV protease cleavage site.

    Depositor

    Jennifer Doudna

    Article

    Liu et al Nat Chem Biol. 2021 Sep;17(9):982-988. d

    Insert

    T. thermophilus Csm6 (codon optimized) (csm6 Synthetic)
    

    Tags

    His-SUMO-TEV

    Expression

    Bacterial

    Promoter

    T7 promoter and lac operator

    Available Since

    Aug. 17, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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20. pLX209-neo-WRN E84A

    Plasmid

    #125789

    Purpose

    constitutive, ectopic expression of an exonuclease-dead mutant of human WRN (E84A)

    Depositor

    Francisca Vazquez

    Article

    Chan et al Nature. 2019 Apr 10. pii: 10.1038/s41586

    Insert

    myc-WRN E84A (WRN Human)
    

    Tags

    5x myc

    Expression

    Mammalian

    Mutation

    E84A (exonuclease-dead)

    Available Since

    June 4, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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