We narrowed to 10,414 results for: 158

1. pAAV.CAG-NLS-EGFP-WPRE-SV40pA-T7-T3-BC(p1-14)

   Plasmid

   #231345

   Purpose

   Single stranded AAV genome with components for tracking AAV genome via AAV-Zombie. Also expresses a nuclear localized EGFP from CAG promoter.

   Depositor

   Viviana Gradinaru

   Article

   Coughlin et al Nat Biotechnol. 2025 Mar 20. doi: 10.103

   Insert

   T7/T3-BC(p1-14)
   

   Use

   AAV

   Tags

   Expression

   Mutation

   Promoter

   Available since

   March 20, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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2. pAAV.BC(p1-10)-CAG-EGFP-W3SL-BC(p1-10)

   Plasmid

   #231347

   Purpose

   Single stranded AAV genome with concatemerization-dependent barcodes, for tracking AAV concatemers via SpECTr. Also expresses EGFP from CAG promoter.

   Depositor

   Viviana Gradinaru

   Article

   Coughlin et al Nat Biotechnol. 2025 Mar 20. doi: 10.103

   Insert

   BC(p1-10)
   

   Use

   AAV

   Tags

   Expression

   Mutation

   Promoter

   Available since

   March 20, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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3. p27.pA.NGFR.mCMV.hPGK.Rab35(S22N).wpre[sequenced]

   Plasmid

   #226766

   Purpose

   Rab35(S22N)

   Depositor

   Ferdinando Pucci

   Article

   Ziglari et al Cancer Res. 2025 Mar 3;85(5):859-874. do

   Insert

   rab35-mutant S22N (RAB35 )
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   March 12, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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4. p26.pA.NGFR.mCMV.hPGK.Rab35(Q67L).wpre[sequenced]

   Plasmid

   #226765

   Purpose

   Rab35(Q67L)

   Depositor

   Ferdinando Pucci

   Article

   Ziglari et al Cancer Res. 2025 Mar 3;85(5):859-874. do

   Insert

   rab35-mutant Q67L (RAB35 )
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   March 12, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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5. CA-0216 CMVTO-hIL6Ra_M4-rens-hIL6-rens-IL6Rb

   Plasmid

   #231194

   Purpose

   Multi-cageIL-6

   Depositor

   Xiaojing Gao

   Article

   Aldrete et al Nat Chem Biol. 2025 Jan 15. doi: 10.1038

   Insert

   hIL6Ra_M4-rens-hIL6-rens-IL6Rb (IL6 Human)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   A228D, N230D, H280S, D281V

   Promoter

   Available since

   Jan. 28, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

6. CA-0248 EF1a_mRens-cageIL-2-c-myc_T2A_ERret-H2M-Renin_T2A-mCherry_Gen2

   Plasmid

   #231208

   Purpose

   Single transcript cageIL-2 (mRens) + ER-renin (H2M) (Lenti)

   Depositor

   Xiaojing Gao

   Article

   Aldrete et al Nat Chem Biol. 2025 Jan 15. doi: 10.1038

   Insert

   mRens-cageIL-2-c-myc_T2A_ERret-H2M-Renin_T2A-mCherry (IL2 Human)
   

   Use

   Lentiviral

   Tags

   Expression

   Mutation

   L80F, R81D, L85V, I86V, I92F

   Promoter

   Available since

   Jan. 28, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

7. CA-0251 CMVTO-c-myc-mono-hIL10 (R5A11M)-rens

   Plasmid

   #231216

   Purpose

   myc-CleaveIL-10

   Depositor

   Xiaojing Gao

   Article

   Aldrete et al Nat Chem Biol. 2025 Jan 15. doi: 10.1038

   Insert

   c-myc-mono-hIL10 (R5A11M)-rens (IL10 Human)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   N36I, N110I, K117N, F129L

   Promoter

   Available since

   Jan. 27, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

8. CA244 CMVTO_ERret-H2M-Renin_T2A_mRens-cageIL-10-c-myc_T2A-mCherry

   Plasmid

   #231205

   Purpose

   Single transcript cageIL-10 (mRens) + ER-renin (H2M)

   Depositor

   Xiaojing Gao

   Article

   Aldrete et al Nat Chem Biol. 2025 Jan 15. doi: 10.1038

   Insert

   ERret-H2M-Renin_T2A_mRens-cageIL-10-c-myc_T2A-mCherry (IL10 Human)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   L147I, R148H, I203V, L290V

   Promoter

   Available since

   Jan. 27, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

9. CA-0091 CMVTO-mono-hIL10-R5A11M-rens-3GS-IL10Ra

   Plasmid

   #231191

   Purpose

   CageIL-10-monomer

   Depositor

   Xiaojing Gao

   Article

   Aldrete et al Nat Chem Biol. 2025 Jan 15. doi: 10.1038

   Insert

   mono-hIL10-R5A11M-rens-3GS-IL10Ra (IL10 Human)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   N36I, N110I, K117N, F129L

   Promoter

   Available since

   Jan. 27, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. CA-0252 CMVTO-c-myc-mono-hIL10 (R5A11M)-rens-cleaved

    Plasmid

    #231215

    Purpose

    Cleaved-myc-IL-10

    Depositor

    Xiaojing Gao

    Article

    Aldrete et al Nat Chem Biol. 2025 Jan 15. doi: 10.1038

    Insert

    c-myc-mono-hIL10 (R5A11M)-rens-cleaved (IL10 Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    N36I, N110I, K117N, F129L

    Promoter

    Available since

    Jan. 24, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

11. CA173 CMVTO-mono-hIL10-R5A11M-rens-3GS-IL10Ra-c-myc

    Plasmid

    #231214

    Purpose

    CageIL-10-myc

    Depositor

    Xiaojing Gao

    Article

    Aldrete et al Nat Chem Biol. 2025 Jan 15. doi: 10.1038

    Insert

    mono-hIL10-R5A11M-rens-3GS-IL10Ra-c-myc (IL10 Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    N36I, N110I, K117N, F129L

    Promoter

    Available since

    Jan. 24, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. CA-0230 EF1a_Puro_ERret-H2M-Renin_T2A_mRens-cageIL-10-c-myc_T2A-mCherry_Gen2

    Plasmid

    #231207

    Purpose

    Single transcript cageIL-10 (mRens) + ER-renin (H2M) (Lenti)

    Depositor

    Xiaojing Gao

    Article

    Aldrete et al Nat Chem Biol. 2025 Jan 15. doi: 10.1038

    Insert

    Puro_ERret-H2M-Renin_T2A_mRens-cageIL-10-c-myc_T2A-mCherry (IL10 Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    L147I, R148H, I203V, L290V

    Promoter

    Available since

    Jan. 16, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

13. CROP-seq-copGFP-v2-no-scaffold

    Plasmid

    #228520

    Purpose

    CROP-seq-puro-v2 with scaffold sequence removed for the insertion of CRISPRmap Opool with guide, scaffold and barcode sequences, using copGFP as selection marker

    Depositor

    Jellert Gaublomme

    Article

    Gu et al Nat Biotechnol. 2024 Oct 7. doi: 10.1038

    Type

    Empty backbone

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Jan. 9, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. pLIX401 APE1 CI

    Plasmid

    #227191

    Purpose

    Inducible lentiviral expression of CI (Catalytically Inactive) APE1

    Depositor

    David Pellman

    Article

    Tang et al Nature. 2022 Jun;606(7916):930-936. doi:

    Insert

    apurinic/apyrimidinic endonuclease APE1 (APEX1 Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Bacterial and Mammalian

    Mutation

    H309N

    Promoter

    Available since

    Nov. 7, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. SpCas9-NRCH-CGBE1

    Plasmid

    #198557

    Purpose

    Expresses human codon-optimized SpCas9-NRCH-CGBE1 and blasticidin resistance: EFS promoter-SpCas9-NRCH-CGBE1-NLS-FLAG-P2A-BSD

    Depositor

    Hyongbum Kim

    Article

    Kim et al Nat Biotechnol. 2024 Mar;42(3):484-497.

    Insert

    SpCas9-NRCH-CGBE1
    

    Use

    CRISPR and Lentiviral

    Tags

    BSD, FLAG, and NLS

    Expression

    Mammalian

    Mutation

    Promoter

    EFS

    Available since

    Nov. 5, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. SpCas9-NG-ABE8.17-m+V106W

    Plasmid

    #198534

    Purpose

    Expresses human codon-optimized SpCas9-NG-ABE8.17-m+V106W and blasticidin resistance: EFS promoter-SpCas9-NG-ABE8.17-m+V106W-NLS-FLAG-P2A-BSD

    Depositor

    Hyongbum Kim

    Article

    Kim et al Nat Biotechnol. 2024 Mar;42(3):484-497.

    Insert

    SpCas9-NG-ABE8.17-m+V106W
    

    Use

    CRISPR and Lentiviral

    Tags

    BSD, FLAG, and NLS

    Expression

    Mammalian

    Mutation

    Promoter

    EFS

    Available since

    Nov. 5, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. pFB-D3-ASK1

    Plasmid

    #226619

    Purpose

    Co-expression of D3 and ASK1 complex in insect cells

    Depositor

    Ning Zheng

    Article

    Shabek et al Nature. 2018 Nov;563(7733):652-656. doi:

    Inserts

    D3
    ASK1 (SKP1 Mustard Weed)
    

    Use

    Tags

    His tag followed with three copies of Msyb

    Expression

    Insect

    Mutation

    The flexible loop in D3 (Q478-D515) can be remove…

    Promoter

    Polyhedrin

    Available since

    Oct. 15, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. Control-Control-LRG-GFP

    Plasmid

    #225873

    Purpose

    Two copies of guide RNA targeting a control sequence

    Depositor

    Janai Carr-Ascher

    Article

    Freeland et al Clin Cancer Res. 2024 Aug 23. doi: 10.11

    Insert

    Control
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Oct. 15, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. RNF149 shRNA-TRE

    Plasmid

    #225337

    Purpose

    shRNAmir backbone under tet-operator for RNA interference, with YFP

    Depositor

    Huda Zoghbi

    Article

    Kim et al Neuron. 2023 Mar 15;111(6):824-838.e7. d

    Insert

    RNF149 shRNA (Rnf149 Mouse)
    

    Use

    AAV and RNAi

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    TRE (tetracycline-responsive element)

    Available since

    Sept. 11, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. pLenti-IRAK4-mScarlet-P2A-Puro

    Plasmid

    #221237

    Purpose

    Stable expression of mouse IRAK4-mScarlet after Lentiviral transduction

    Depositor

    Jonathan Kagan

    Article

    Fisch et al Nature. 2024 Jul;631(8021):635-644. doi:

    Insert

    IRAK4 (Irak4 Mouse)
    

    Use

    Lentiviral

    Tags

    mScarlet

    Expression

    Mutation

    Promoter

    Available since

    July 10, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

21. pCMV-NKp46-Fc

    Plasmid

    #221857

    Purpose

    Express human NKp46 (full-length) with C-terminal human IgG1Fc tag in mammalian cell.

    Depositor

    Judy Lieberman

    Article

    Sen Santara et al Nature. 2023 Apr;616(7956):348-356. doi:

    Insert

    NKp46 (NCR1 Human)
    

    Use

    Tags

    Human IgG1Fc tag

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    July 3, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

22. pJT309 RapInducible1-ActivatorCloneSite-Citrine

    Plasmid

    #187321

    Purpose

    Rapamycin inducible genetic circuit with cloning site for activator domains

    Depositor

    Michael Bassik, Lacra Bintu

    Article

    Tycko et al Nat Biotechnol. 2024 Nov 1. doi: 10.1038

    Type

    Empty backbone

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    May 6, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

23. pAAV-cFOS-FRB-VP16-P2A-EGFP

    Plasmid

    #210510

    Purpose

    expresses cFOS-FRB-VP16 and EGFP component in rat hippocampal neuron cells

    Depositor

    Dongmin Lee

    Article

    Cui et al Nat Chem Biol. 2024 Mar;20(3):353-364. d

    Insert

    FRB-VP16-P2A-EGFP
    

    Use

    AAV

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    cFos

    Available since

    Jan. 26, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

24. DRD2-V2tail-TevN-BLITz-TetR-FKBP

    Plasmid

    #210514

    Purpose

    expresses DRD2-V2tail-TevN-BLITz-TetR-FKBP component in mammalian cells

    Depositor

    Dongmin Lee

    Article

    Cui et al Nat Chem Biol. 2024 Mar;20(3):353-364. d

    Insert

    DRD2-V2tail-TevN-BLITz-TetR-FKBP
    

    Use

    Tags

    HA signal FALG

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    Jan. 26, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

25. Qt-FLAG-TGA-rt9us-antiGFP

    Plasmid

    #206954

    Purpose

    Mammalian expression of Qt EMcapsulins targeting GFP with stoichiometry control (~8% surface decoration)

    Depositor

    Gil Westmeyer

    Article

    Sigmund et al Nat Biotechnol. 2023 Apr 17. doi: 10.103

    Insert

    QtEnc, antiGFP-intrabody
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Jan. 2, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

26. Qt-FLAG-TAA-rt20s-antiGFP

    Plasmid

    #206955

    Purpose

    Mammalian expression of Qt EMcapsulins targeting GFP with stoichiometry control (~6% surface decoration)

    Depositor

    Gil Westmeyer

    Article

    Sigmund et al Nat Biotechnol. 2023 Apr 17. doi: 10.103

    Insert

    QtEnc, antiGFP-intrabody
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Sept. 29, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

27. 1M-Qt-FLAG-TGA-rt20s-antiGFP

    Plasmid

    #206953

    Purpose

    Mammalian expression of 1M-Qt EMcapsulins targeting GFP with stoichiometry control (~20% surface decoration)

    Depositor

    Gil Westmeyer

    Article

    Sigmund et al Nat Biotechnol. 2023 Apr 17. doi: 10.103

    Insert

    MmMT3, QtEnc, antiGFP-intrabody
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Sept. 29, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

28. mEos3.2trLAT-P

    Plasmid

    #203747

    Purpose

    Encodes the transmembrane domain from mouse LAT with mEos3.2 fused on the N terminus. The palmitoylation site at C27 is mutated to A. Used as a fluorescent plasma membrane probe.

    Depositor

    Sarah Veatch

    Article

    Shelby et al Nat Chem Biol. 2023 Jun;19(6):750-758. d

    Insert

    trLAToC27A (Lat Mouse)
    

    Use

    Tags

    ER translocation signal - mEos3.2

    Expression

    Mammalian

    Mutation

    C27A

    Promoter

    Available since

    Aug. 7, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

29. trLATm1PtoLmEos3.2

    Plasmid

    #203749

    Purpose

    Encodes the transmembrane domain from human LAT with mEos3.2 fused on the C terminus. Prolines P8 and P17 in the LAT transmembrane domain mutated to L. Used as a fluorescent plasma membrane probe.

    Depositor

    Sarah Veatch

    Article

    Shelby et al Nat Chem Biol. 2023 Jun;19(6):750-758. d

    Insert

    trLATm1 (PtoL) (LAT Human)
    

    Use

    Tags

    mEos3.2

    Expression

    Mammalian

    Mutation

    P8L, P17L

    Promoter

    Available since

    Aug. 7, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

30. B*46:01:01

    Plasmid

    #203250

    Purpose

    Overexpress HLA allele

    Depositor

    Catherine Wu, Derin Keskin

    Article

    Sarkizova et al Nat Biotechnol. 2020 Feb;38(2):199-209.

    Insert

    B*46:01:01 (HLA-B Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    July 10, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge