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Showing: 541 - 560 of 26843 results

  2. pTwist-SARS-CoV-2 Spike-deltaC18 VOC-501Y.V2 (B.1.351) - McGuire Mutations

    Plasmid
    #212388
    Purpose
    Encodes SARS-CoV-2 spike D80A,D215G,K417N,E484K,N501Y,D614G for pseudovirus production
    Depositor
    Alejandro Balazs
    Article
    Roederer et al medRxiv [Preprint]. 2024 Mar 7:2024.03.0
    Insert
    SARS-CoV-2 Spike D80A,D215G,K417N,E484K,N501Y,D614G (S Severe acute respiratory syndrome coronavirus 2)
    Use
    Tags
    Expression
    Mammalian
    Mutation
    D80A,D215G,K417N,E484K,N501Y,D614G
    Promoter
    CAG
    Available since
    Sept. 13, 2024
    Availability
    Academic Institutions and Nonprofits only
    212388-plasmid-map-sequence-id-431627

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  3. pTwist-SARS-CoV-2 Spike-deltaC18 VOC-501Y.V2 (B.1.351) - All Mutations

    Plasmid
    #212381
    Purpose
    Encodes SARS-CoV-2 spike L18F,D80A,D215G,L242H,A243I,Q414N,E484K,N501Y,D614G,A701V for pseudovirus production
    Depositor
    Alejandro Balazs
    Article
    Roederer et al medRxiv [Preprint]. 2024 Mar 7:2024.03.0
    Insert
    SARS-CoV-2 Spike L18F,D80A,D215G,L242H,A243I,Q414N,E484K,N501Y,D614G,A701V (S Severe acute respiratory syndrome coronavirus 2)
    Use
    Tags
    Expression
    Mammalian
    Mutation
    L18F,D80A,D215G,L242H,A243I,Q414N,E484K,N501Y,D61…
    Promoter
    CAG
    Available since
    Sept. 13, 2024
    Availability
    Academic Institutions and Nonprofits only
    212381-plasmid-map-sequence-id-431621

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  5. pTwist-SARS-CoV-2 Spike-deltaC18 D614G (GGT) Q677H (CAT) D936Y (TAT)

    Plasmid
    #212379
    Purpose
    Encodes SARS-CoV-2 spike D614G, Q677H, D936Y for pseudovirus production
    Depositor
    Alejandro Balazs
    Article
    Roederer et al medRxiv [Preprint]. 2024 Mar 7:2024.03.0
    Insert
    SARS-CoV-2 Spike D614G, Q677H, D936Y (S Severe acute respiratory syndrome coronavirus 2)
    Use
    Tags
    Expression
    Mammalian
    Mutation
    D614G, Q677H, D936Y
    Promoter
    CAG
    Available since
    Sept. 13, 2024
    Availability
    Academic Institutions and Nonprofits only
    212379-plasmid-map-sequence-id-431620

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  6. pTwist-SARS-CoV-2 Spike-deltaC18 SAK006840 VOC-501Y.V2 (B.1.351v3) - No RBD Mutations

    Plasmid
    #212380
    Purpose
    Encodes SARS-CoV-2 spike D80A, deltaL242-L244, R246I, D614G, A701V for pseudovirus production
    Depositor
    Alejandro Balazs
    Article
    Roederer et al medRxiv [Preprint]. 2024 Mar 7:2024.03.0
    Insert
    SARS-CoV-2 Spike D80A, G215D, deltaL242-L244, R246I, D614G, A701V (S Severe acute respiratory syndrome coronavirus 2)
    Use
    Tags
    Expression
    Mammalian
    Mutation
    D80A, G215D, deltaL242-L244, R246I, D614G, A701V
    Promoter
    CAG
    Available since
    Sept. 13, 2024
    Availability
    Academic Institutions and Nonprofits only
    212380-plasmid-map-sequence-id-433143

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  7. pCL051 AAVS1-9xTetO-nTATAchr21-IGKleader-Cas9site-hIgG1_FC-Myc-PDGFRb-T2A-Citrine-PolyA

    Plasmid
    #188745
    Purpose
    Donor vector for integrating nonTATAchr21 promoter-driven dual surface marker/mCitrine fluorescent reporter at AAVS1 locus
    Depositor
    Lacra Bintu, Michael Bassik
    Article
    Tycko et al Nat Biotechnol. 2024 Nov 1. doi: 10.1038
    Insert
    Surface marker and mCitrine reporter
    Use
    Synthetic Biology
    Tags
    Expression
    Mammalian
    Mutation
    Promoter
    nonTATAchr21
    Available since
    May 7, 2024
    Availability
    Academic Institutions and Nonprofits only
    188745-plasmid-map-sequence-id-371435

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  8. pCL053 AAVS1-9xTetO-nTATAchrX-IGKleader-Cas9site-hIgG1_FC-Myc-PDGFRb-T2A-Citrine-PolyA

    Plasmid
    #188746
    Purpose
    Donor vector for integrating nonTATAchrX promoter-driven dual surface marker/mCitrine fluorescent reporter at AAVS1 locus
    Depositor
    Lacra Bintu, Michael Bassik
    Article
    Tycko et al Nat Biotechnol. 2024 Nov 1. doi: 10.1038
    Insert
    Surface marker and mCitrine reporter
    Use
    Synthetic Biology
    Tags
    Expression
    Mammalian
    Mutation
    Promoter
    nonTATAchrX
    Available since
    May 7, 2024
    Availability
    Academic Institutions and Nonprofits only
    188746-plasmid-map-sequence-id-373413

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  9. pSLQ8629 pHR-HREYBTATA-RR12EE345L-C term (406) dLbCpf1-2XNLS-miniVPR-mCherry-EFS-Puro-WPRE

    Plasmid
    #140227
    Purpose
    Hypoxia-inducible expression of leucine zipper with C terminal dCpf1 (Cas12a) 406-split half fused to miniVPR. Constitutive EFS-driven puromycin resistance.
    Depositor
    Stanley Qi
    Article
    Kempton et al Mol Cell. 2020 Jan 30. pii: S1097-2765(2
    Insert
    zipper with dLbCpf1 (Cas12a) C terminal half (406) fused to miniVPR
    Use
    Lentiviral
    Tags
    Expression
    Mammalian
    Mutation
    Promoter
    HRE (Hypoxia inducible)
    Available since
    April 21, 2020
    Availability
    Academic Institutions and Nonprofits only
    140227-plasmid-map-sequence-id-291996

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  10. WNV strain-NY99 NS2B-NS3 protease fusion with non cleavable linker with mutation K to A to reduce autoproteolysis

    Plasmid
    #228660
    Purpose
    Bacterial expression of the fusion of the NS2B-NS3 protease from West Nile virus with an H163A - catalytically inactive mutation for xxxxx
    Depositor
    ASAP Discovery, Frank von Delft
    Insert
    West Nile portion of NS2B protease fused to NS3
    Use
    Tags
    His-Twin Strep-Tev
    Expression
    Bacterial
    Mutation
    H163A - catalytically inactive/West Nile Virus NS…
    Promoter
    Available since
    Feb. 18, 2025
    Availability
    Industry, Academic Institutions, and Nonprofits
    228660-plasmid-map-sequence-id-461601

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  11. pTwist-SARS-CoV-2 Spike-deltaC18 Q493R (CGA) Q498R (CGA) N501Y (TAT) Y505H (CAT)

    Plasmid
    #212498
    Purpose
    Encodes SARS-CoV-2 spike Q493R, Q498R, N501Y, Y505H for pseudovirus production
    Depositor
    Alejandro Balazs
    Article
    Roederer et al medRxiv [Preprint]. 2024 Mar 7:2024.03.0
    Insert
    SARS-CoV-2 Spike Q493R, Q498R, N501Y, Y505H (S Severe acute respiratory syndrome coronavirus 2)
    Use
    Tags
    Expression
    Mammalian
    Mutation
    Q493R, Q498R, N501Y, Y505H
    Promoter
    CAG
    Available since
    Sept. 13, 2024
    Availability
    Academic Institutions and Nonprofits only
    212498-plasmid-map-sequence-id-432816

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  12. pTwist-SARS-CoV-2 Spike-deltaC18 Q493R (CGA) G496S (TCA) Q498R (CGA) N501Y (TAT) Y505H (CAT)

    Plasmid
    #212477
    Purpose
    Encodes SARS-CoV-2 spike Q493R, G496S, Q498R, N501Y, Y505H for pseudovirus production
    Depositor
    Alejandro Balazs
    Article
    Roederer et al medRxiv [Preprint]. 2024 Mar 7:2024.03.0
    Insert
    SARS-CoV-2 Spike Q493R, G496S, Q498R, N501Y, Y505H (S Severe acute respiratory syndrome coronavirus 2)
    Use
    Tags
    Expression
    Mammalian
    Mutation
    Q493R, G496S, Q498R, N501Y, Y505H
    Promoter
    CAG
    Available since
    Sept. 13, 2024
    Availability
    Academic Institutions and Nonprofits only
    212477-plasmid-map-sequence-id-432802

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  13. pACAGW-ChR2-Venus-AAV (AAV1)

    Viral Prep
    #20071-AAV1
    Purpose
    Ready-to-use AAV1 particles produced from pACAGW-ChR2-Venus-AAV (#20071). In addition to the viral particles, you will also receive purified pACAGW-ChR2-Venus-AAV plasmid DNA. CAG-driven, channelrhodopsin fused to Venus for optogenetic activation. These AAV preparations are suitable purity for injection into animals.
    Depositor
    Karel Svoboda
    Article
    Leopoldo et al Nature. 2009 Jan 18.
    Promoter
    CAGG
    Tags
    Venus
    Available since
    Feb. 21, 2018
    Availability
    Academic Institutions and Nonprofits only

  14. pACAGW-ChR2-Venus-AAV (AAV9)

    Viral Prep
    #20071-AAV9
    Purpose
    Ready-to-use AAV9 particles produced from pACAGW-ChR2-Venus-AAV (#20071). In addition to the viral particles, you will also receive purified pACAGW-ChR2-Venus-AAV plasmid DNA. CAG-driven, channelrhodopsin fused to Venus for optogenetic activation. These AAV preparations are suitable purity for injection into animals.
    Depositor
    Karel Svoboda
    Article
    Leopoldo et al Nature. 2009 Jan 18.
    Promoter
    CAGG
    Tags
    Venus
    Available since
    March 15, 2018
    Availability
    Academic Institutions and Nonprofits only

  15. pAAV-CAG-emiRFP670 (AAV1)

    Viral Prep
    #197200-AAV1
    Purpose
    Ready-to-use AAV1 particles produced from pAAV-CAG-emiRFP670 (#197200). In addition to the viral particles, you will also receive purified pAAV-CAG-emiRFP670 plasmid DNA. CAG-driven expression of emiRFP670. These AAV preparations are suitable purity for injection into animals.
    Depositor
    Kiryl Piatkevich
    Article
    Zhang et al Nat Methods. 2023 Sep 4. doi: 10.1038/s4
    Promoter
    Tags
    None
    Available since
    Feb. 7, 2025
    Availability
    Academic Institutions and Nonprofits only

  16. pAAV-EF1α-F-FLEX-mNaChBac-T2A-tdTomato (AAV8)

    Viral Prep
    #60658-AAV8
    Purpose
    Ready-to-use AAV8 particles produced from pAAV-EF1α-F-FLEX-mNaChBac-T2A-tdTomato (#60658). In addition to the viral particles, you will also receive purified pAAV-EF1α-F-FLEX-mNaChBac-T2A-tdTomato plasmid DNA. CAG-driven, Flp-dependent expression of the voltage-gated Na+ channel mNaChBac-T2A-tdTomato. These AAV preparations are suitable purity for injection into animals.
    Depositor
    Massimo Scanziani
    Article
    Xue et al Nature. 2014 Jul 31;511(7511):596-600. d
    Promoter
    EF1α
    Tags
    None
    Available since
    Oct. 21, 2024
    Availability
    Academic Institutions and Nonprofits only

  17. pAAV-Ef1a-DIO C1V1 (t/t)-TS-EYFP (AAV9)

    Viral Prep
    #35497-AAV9
    Purpose
    Ready-to-use AAV9 particles produced from pAAV-Ef1a-DIO C1V1 (t/t)-TS-EYFP (#35497). In addition to the viral particles, you will also receive purified pAAV-Ef1a-DIO C1V1 (t/t)-TS-EYFP plasmid DNA. EFIa-driven, Cre-dependent, C1V1 (t/t) fused to EYFP for optogenetic activation. These AAV preparations are suitable purity for injection into animals.
    Depositor
    Karl Deisseroth
    Article
    Yizhar et al Nature. 2011 Jul 27;477(7363):171-8. doi
    Promoter
    EF1a
    Tags
    EYFP (Cre-dependent)
    Available since
    March 30, 2018
    Availability
    Academic Institutions and Nonprofits only

  18. pAAV-Syn-ChrimsonR-tdT (AAV9)

    Viral Prep
    #59171-AAV9
    Purpose
    Ready-to-use AAV9 particles produced from pAAV-Syn-ChrimsonR-tdT (#59171). In addition to the viral particles, you will also receive purified pAAV-Syn-ChrimsonR-tdT plasmid DNA. Syn-driven ChrimsonR-tdTomato expression for optogenetic neural activation. These AAV preparations are suitable purity for injection into animals.
    Depositor
    Edward Boyden
    Article
    Klapoetke et al Nat Methods. 2014 Mar;11(3):338-46. doi:
    Promoter
    Syn
    Tags
    tdTomato
    Available since
    Feb. 7, 2018
    Availability
    Academic Institutions and Nonprofits only

  19. pAAV-Syn-ChrimsonR-tdT (AAV1)

    Viral Prep
    #59171-AAV1
    Purpose
    Ready-to-use AAV1 particles produced from pAAV-Syn-ChrimsonR-tdT (#59171). In addition to the viral particles, you will also receive purified pAAV-Syn-ChrimsonR-tdT plasmid DNA. Syn-driven ChrimsonR-tdTomato expression for optogenetic neural activation. These AAV preparations are suitable purity for injection into animals.
    Depositor
    Edward Boyden
    Article
    Klapoetke et al Nat Methods. 2014 Mar;11(3):338-46. doi:
    Promoter
    Syn
    Tags
    tdTomato
    Available since
    Feb. 7, 2018
    Availability
    Academic Institutions and Nonprofits only

  20. pAAV-Syn-ChrimsonR-tdT (AAV5)

    Viral Prep
    #59171-AAV5
    Purpose
    Ready-to-use AAV5 particles produced from pAAV-Syn-ChrimsonR-tdT (#59171). In addition to the viral particles, you will also receive purified pAAV-Syn-ChrimsonR-tdT plasmid DNA. Syn-driven ChrimsonR-tdTomato expression for optogenetic neural activation. These AAV preparations are suitable purity for injection into animals.
    Depositor
    Edward Boyden
    Article
    Klapoetke et al Nat Methods. 2014 Mar;11(3):338-46. doi:
    Promoter
    Syn
    Tags
    tdTomato
    Available since
    Feb. 7, 2018
    Availability
    Academic Institutions and Nonprofits only
Showing: 541 - 560 of 26843 results