We narrowed to 737 results for: Tcta

1. LRRK2 gRNA (BRDN0001148003)

   Plasmid

   #77332

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human LRRK2

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   LRRK2 (LRRK2 Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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2. BRD2 gRNA (BRDN0001148966)

   Plasmid

   #77985

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human BRD2

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   BRD2 (BRD2 Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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3. LYN gRNA (BRDN0001148376)

   Plasmid

   #77026

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human LYN

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   LYN (LYN Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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4. pSpdCas9-huTET1CD-T2A-mCherry(PX458)-SgmouseTSDR-1

   Plasmid

   #129053

   Purpose

   targeted DNA demethylation_mouse_TSDR, expression of dCas9-huTET1CD-T2A-mCherry and sgRNA1 targeting mouse TSDR

   Depositor

   Julia K Polansky

   Article

   Kressler et al Front Immunol. 2021 Jan 7;11:609891. doi

   Insert

   dCas9-huTET1CD, SgRNA1 (mouseTSDR)
   

   Tags

   HA-Tag, NLS and T2A-mCherry

   Expression

   Mammalian

   Mutation

   dCas9 (D10A;H840A)

   Promoter

   CbH (for dCas9-huTET1CD-T2A-EGFP) U6 (for sgRNA)

   Available Since

   Jan. 25, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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5. TRCN0000297275

   Plasmid

   #78152

   Purpose

   shCDK4 targeting 3UTR

   Depositor

   William Hahn

   Article

   Hong et al Nat Commun. 2016 Jun 22;7:11987. doi: 10

   Insert

   CDK4 (CDK4 Human)
   

   Use

   RNAi

   Promoter

   hU6

   Available Since

   June 22, 2016

   Availability

   Academic Institutions and Nonprofits only

6. DYRK1A gRNA (BRDN0001148321)

   Plasmid

   #76754

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human DYRK1A

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   DYRK1A (DYRK1A Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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7. pLKO.1-shDnd1-No7

   Plasmid

   #70068

   Purpose

   TRC lentiviral vector for shRNA against mouse Dnd1 #7

   Depositor

   Thomas Tuschl

   Article

   Yamaji et al Nature. 2017 Mar 23;543(7646):568-572. d

   Insert

   Dnd1 (Dnd1 Mouse)
   

   Use

   Lentiviral

   Expression

   Mammalian

   Promoter

   EF1alpha

   Available Since

   Nov. 22, 2017

   Availability

   Academic Institutions and Nonprofits only

8. BAZ1B gRNA (BRDN0001144929)

   Plasmid

   #76132

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human BAZ1B

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   BAZ1B (BAZ1B Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

9. MAP4K3 gRNA (BRDN0001145020)

   Plasmid

   #76405

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human MAP4K3

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   MAP4K3 (MAP4K3 Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. MAP2K3 gRNA (BRDN0001147239)

    Plasmid

    #76381

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human MAP2K3

    Depositor

    David Root, John Doench

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    MAP2K3 (MAP2K3 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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11. CSNK1D gRNA (BRDN0001149348)

    Plasmid

    #76716

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human CSNK1D

    Depositor

    David Root, John Doench

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    CSNK1D (CSNK1D Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. LentiCRISPR-B_sgRNA_DIS3 (pP18(T)_A5-AVA4073)

    Plasmid

    #239308

    Purpose

    Lentiviral vector expressing Cas9-P2A-Blasticidin and an sgRNA targeting DIS3

    Depositor

    Andrei Alexandrov

    Article

    Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

    Insert

    U6-driven sgRNA targeting DIS3 (DIS3 Human)
    

    Use

    CRISPR and Lentiviral

    Available Since

    Aug. 4, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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13. LentiCRISPR-B_2xsgRNAs_ZCRB1 (pAVA3300)

    Plasmid

    #239325

    Purpose

    Lentiviral vector expressing Cas9-P2A-Blasticidin and two sgRNA stargeting ZCRB1

    Depositor

    Andrei Alexandrov

    Article

    Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

    Insert

    U6-driven sgRNA1 and 7SK-driven sgRNA2 targeting ZCRB1 (ZCRB1 Human)
    

    Use

    CRISPR and Lentiviral

    Available Since

    Aug. 4, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. LentiCRISPR-B_sgRNA_EXOSC4 (pP18(T)_C11-AVA4065)

    Plasmid

    #239302

    Purpose

    Lentiviral vector expressing Cas9-P2A-Blasticidin and an sgRNA targeting EXOSC4

    Depositor

    Andrei Alexandrov

    Article

    Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

    Insert

    U6-driven sgRNA targeting EXOSC4 (EXOSC4 Human)
    

    Use

    CRISPR and Lentiviral

    Available Since

    Aug. 4, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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15. pKLV2-U6gRNA5(hPTPN11_1k)-PGKpuro2ABFP-W

    Plasmid

    #208427

    Purpose

    Lentiviral gRNA plasmid targeting human PTPN11 gene, co-expression of BFP tag

    Depositor

    Sok Ching Cheong

    Article

    Chai et al Heliyon. 2024 Oct 22;10(21):e39677. doi:

    Insert

    PTPN11 (PTPN11 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Mutation

    N/A

    Promoter

    human U6

    Available Since

    July 1, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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16. pAAV-hSyn-mCherry-Rorb sesRNA-2a-msFlag-2a-tTA2-WPRE

    Plasmid

    #239029

    Purpose

    Expression of mCherry, sesRNA in mammalian cells, with msFlag and tTA2 as efRNA.

    Depositor

    Josh Huang

    Article

    Qian et al Nature. 2022 Oct;610(7933):713-721. doi:

    Insert

    sesRNA for mouse Rorb (Rorb Mouse)
    

    Use

    AAV

    Expression

    Mammalian

    Promoter

    hSyn

    Available Since

    May 14, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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17. pXPR_BRD051d_sgCiPELO #1

    Plasmid

    #229017

    Purpose

    Expression of CRISPRi PELO sgRNA #1

    Depositor

    Francisca Vazquez

    Article

    Borck et al Nature. 2025 Feb 5. doi: 10.1038/s41586-

    Insert

    PELO (PELO Human)
    

    Use

    CRISPR

    Expression

    Mammalian

    Available Since

    March 20, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. pLCHKOv3-mClover-intergenic-As

    Plasmid

    #209036

    Purpose

    Lentiviral vector expressing mClover3 along with U6 driven hybrid guide (hgRNA) targeting two intergenic sites in the human genome using SpCas9 and AsCas12a nucleases (CHyMErA system), respectively

    Depositor

    Thomas Gonatopoulos-Pournatzis

    Article

    Xiao et al Mol Cell. 2024 Jul 11;84(13):2553-2572.e

    Insert

    intergenic hgRNA with SpCas9 tracrRNAv1 & AsCas12a DR
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    U6

    Available Since

    June 20, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. pLCHKOv3-mClover-intergenic_2-As

    Plasmid

    #218814

    Purpose

    Lentiviral vector expressing mClover3 along with U6 driven hybrid guide (hgRNA) targeting two intergenic sites in the human genome using SpCas9 and AsCas12a nucleases (CHyMErA system), respectively

    Depositor

    Thomas Gonatopoulos-Pournatzis

    Article

    Xiao et al Mol Cell. 2024 Jul 11;84(13):2553-2572.e

    Insert

    intergenic hgRNA with SpCas9 tracrRNAv1 & AsCas12a DR
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    U6

    Available Since

    June 20, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. pLCHKOv3-mClover-intergenic_3-As

    Plasmid

    #218815

    Purpose

    Lentiviral vector expressing mClover3 along with U6 driven hybrid guide (hgRNA) targeting two intergenic sites in the human genome using SpCas9 and AsCas12a nucleases (CHyMErA system), respectively

    Depositor

    Thomas Gonatopoulos-Pournatzis

    Article

    Xiao et al Mol Cell. 2024 Jul 11;84(13):2553-2572.e

    Insert

    intergenic hgRNA with SpCas9 tracrRNAv1 & AsCas12a DR
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    U6

    Available Since

    June 20, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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