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We narrowed to 94,716 results for: lias

Showing: 1111 - 1140 of 94716 results

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PBbtCRISPRko.v1

Pooled Library

#213928

Purpose

Uses the PiggyBac transposon system to deliver the library into hard to transduce cells

Depositor

Wenfang Spring Tan

Article

Tan et al PLoS Pathog. 2023 Dec 6;19(12):e1011822.

Expression

Mammalian

Use

CRISPR and Lentiviral

Available since

April 9, 2024

Availability

Academic Institutions and Nonprofits only
pRG01-MCAP_MET

Pooled Library

#123361

Purpose

pRG01 with barcoded MCAP_Met crRNA array library cloned in, targeting combinations of metastasis drivers.

Depositor

Sidi Chen

Article

Chow et al Nat Methods. 2019 May;16(5):405-408. doi

Expression

Mammalian

Species

Synthetic

Use

CRISPR and Lentiviral

Available since

June 10, 2019

Availability

Academic Institutions and Nonprofits only
Lenti-human-TF-gRNA-puromycin

Pooled Library

#162275

Purpose

This is a gRNA library targeting on ~1600 human transcription factors for genetic screening.

Depositor

Chunliang Li

Article

Zhang et al Elife. 2020 Oct 1;9. pii: 57858. doi: 10

Species

Homo sapiens

Use

Lentiviral

Available since

Dec. 15, 2020

Availability

Academic Institutions and Nonprofits only
MORF library without GFP and mCherry controls

Pooled Library

#192821

Purpose

Barcoded transcription factor ORF library for high throughput screening

Depositor

Feng Zhang

Article

Joung et al Cell. 2023 Jan 5;186(1):209-229.e26. doi

Expression

Mammalian

Species

Homo sapiens

Use

Lentiviral

Available since

Jan. 11, 2023

Availability

Academic Institutions and Nonprofits only
Human Kinase Domain-Focused CRISPR Knockout Library

Pooled Library

#117725

Purpose

gRNAs targeting the kinase domain of human protein kinases

Depositor

Christopher Vakoc

Article

Tarumoto et al Mol Cell. 2018 Feb 28. pii: S1097-2765(1

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Jan. 4, 2019

Availability

Academic Institutions and Nonprofits only
Pan-cancer CasRx lncRNA Albarossa library

Pooled Library

#212966

Purpose

The human CasRx CRISPR lentiviral library encodes 75,725 gRNA arrays (two gRNAs per array) targeting 24,171 lncRNAs.

Depositor

Roland Rad

Article

Montero et al Nat Methods. 2024 Feb 26. doi: 10.1038/s

Expression

Mammalian

Use

CRISPR and Lentiviral

Available since

Feb. 21, 2024

Availability

Academic Institutions and Nonprofits only
Mini-human AsCpf1-based human genome-wide knockout library

Pooled Library

#130630

Purpose

Expresses crRNAs for genome-wide knockout pooled library screening

Depositor

Giulio Draetta

Article

Liu et al Nat Commun. 2019 Jul 17;10(1):3144. doi:

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Sept. 9, 2019

Availability

Academic Institutions and Nonprofits only
Human messenger-RBP sgRNA library

Pooled Library

#168791

Purpose

CRISPR library targets sub-pool of human mRNA binding proteins

Depositor

Martin Turner

Article

Turner et al CRISPR J. 2021 Jun;4(3):427-437. doi: 10

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

July 30, 2021

Availability

Academic Institutions and Nonprofits only
Human Paralog Knockout Library (pgPEN)

Pooled Library

#171172

Purpose

CRISPR library targets human duplicate paralog gene pairs

Depositor

Alice Berger

Article

Parrish et al Cell Rep. 2021 Aug 31;36(9):109597. doi:

Expression

Mammalian

Species

Homo sapiens and Synthetic

Use

CRISPR and Lentiviral

Available since

Sept. 28, 2021

Availability

Academic Institutions and Nonprofits only
Self-targeting epegRNA library, Tiled edits (lRM001)

Pooled Library

#227708

Purpose

CRISPR guide RNA library for prime editing

Depositor

Brittany Adamson

Article

Cirincione et al Nat Methods. 2024 Nov 19. doi: 10.1038/s

Expression

Mammalian

Use

Lentiviral

Available since

Jan. 23, 2025

Availability

Academic Institutions and Nonprofits only
Mouse metabolism knockout library

Pooled Library

#160129

Purpose

CRISPR library targets mouse metabolic genes

Depositor

Kivanc Birsoy

Article

Zhu et al Cell Metab. 2020 Oct 28. pii: S1550-4131

Expression

Mammalian

Species

Mus musculus

Use

CRISPR and Lentiviral

Available since

Nov. 10, 2020

Availability

Academic Institutions and Nonprofits only
Watermelon

Pooled Library

#155257

Purpose

Lineage tracing library

Depositor

Joan Brugge, Aviv Regev

Article

Oren et al Nature. 2021 Aug 11. pii: 10.1038/s41586

Expression

Mammalian

Use

Lentiviral

Available since

Oct. 15, 2021

Availability

Academic Institutions and Nonprofits only
FNLCR CRISPRa Cell Surface

Pooled Library

#207471

Purpose

CRISPR-based activation library with guide RNAs targeting all cell surface proteins.

Depositor

Raj Chari

Article

Yang et al Sci Adv. 2024 Feb 16;10(7):eadj2445. doi

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Jan. 24, 2024

Availability

Academic Institutions and Nonprofits only
Human Metabolic Gene CRISPRa sgRNA library

Pooled Library

#187080

Purpose

Lentiviral CRISPRa library targeting human metabolic genes for activation of gene expression

Depositor

Kivanc Birsoy

Article

Unlu et al Mol Cell. 2022 Aug 4;82(15):2832-2843.e7

Expression

Mammalian

Species

Homo sapiens

Use

Lentiviral

Available since

Oct. 26, 2022

Availability

Academic Institutions and Nonprofits only
Human Lipid Droplet and Metabolism Library

Pooled Library

#191535

Purpose

Lentiviral CRISPR library targeting 1,196 genes related to lipid droplet biology and cell metabolism.

Depositor

James Olzmann

Article

Roberts et al Dev Cell. 2023 Jul 18:S1534-5807(23)0033

Expression

Mammalian

Use

CRISPR and Lentiviral

Available since

March 1, 2023

Availability

Academic Institutions and Nonprofits only
RNA-binding protein pooled CRISPR knockout library

Pooled Library

#141438

Purpose

CRISPR knockout library targets RBPs with 10 sgRNAs/gene

Depositor

Eugene Yeo

Article

Wheeler et al Nat Methods. 2020 May 11. pii: 10.1038/s

Expression

Mammalian

Use

CRISPR and Lentiviral

Available since

May 28, 2020

Availability

Academic Institutions and Nonprofits only
TBG-mTSG

Pooled Library

#113585

Purpose

AAV-CRISPR library for pool mutagenesis of top tumor suppressor genes in mouse liver

Depositor

Sidi Chen

Article

Wang et al Sci Adv. 2018 Feb 28;4(2):eaao5508. doi:

Expression

Mammalian

Use

AAV, CRISPR, Lentiviral, and Luciferase

Available since

July 23, 2019

Availability

Academic Institutions and Nonprofits only
Mouse Metabolic Gene CRISPRa sgRNA library

Pooled Library

#187081

Purpose

Lentiviral CRISPRa library targeting mouse metabolic genes for activation of gene expression

Depositor

Kivanc Birsoy

Article

Unlu et al Mol Cell. 2022 Aug 4;82(15):2832-2843.e7

Expression

Mammalian

Species

Mus musculus

Use

Lentiviral

Available since

Oct. 26, 2022

Availability

Academic Institutions and Nonprofits only
Mouse messenger-RBP sgRNA library

Pooled Library

#169082

Purpose

CRISPR library targeting mouse genes

Depositor

Martin Turner

Article

Turner et al eLife. 2022 Apr 22;11. pii: 72313. doi:

Expression

Mammalian

Species

Mus musculus

Use

CRISPR and Lentiviral

Available since

Sept. 10, 2021

Availability

Academic Institutions and Nonprofits only
Perturb-seq GBC library

Pooled Library

#85968

Purpose

Perturb-seq GBC library

Depositor

Jonathan Weissman

Article

Adamson et al Cell. 2016 Dec 15;167(7):1867-1882.e21.

Expression

Mammalian

Use

CRISPR and Lentiviral

Available since

Feb. 14, 2017

Availability

Academic Institutions and Nonprofits only
pRep-Cap Scanning Saturation Mutagenesis (SSM) pooled library

Pooled Library

#199601

Purpose

pRep-Cap SSM library enables VP1, VP2, and VP3 expression under the control of the endogenous p40 promoter

Depositor

George Church

Article

Ogden et al Science. 2019 Nov 29;366(6469):1139-1143

Expression

Mammalian

Species

Aav2

Use

AAV

Available since

June 13, 2023

Availability

Academic Institutions and Nonprofits only
Human lentiviral CRISPR library_v1

Pooled Library

#69763

Purpose

Genome-scale sgRNA screening library in lentiviral vector pLB, targeting 20,121 human protein-coding genes

Depositor

Haoquan Wu

Article

Ma et al Cell Rep. 2015 Jul 28;12(4):673-83. doi:

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Feb. 9, 2016

Availability

Academic Institutions and Nonprofits only
mTF-CRISPRai

Pooled Library

#122131

Purpose

Expresses gRNAs for mouse transcription factor-CRISPR activation

Depositor

Stanley Qi

Article

Liu et al Cell Stem Cell. 2018 Sep 28. pii: S1934-

Expression

Mammalian

Species

Mus musculus

Use

CRISPR and Lentiviral

Available since

April 25, 2019

Availability

Academic Institutions and Nonprofits only
BARBEKO sgRNA library

Pooled Library

#174163

Purpose

iBARed cytosine Base Editing-mediated gene KnockOut (BARBEKO) sgRNA library; This library leverages CRISPR cytosine base editors for genome-scale knockout screens.

Depositor

Wensheng Wei

Article

Xu et al Nat Biotechnol. 2021 Jun 21. pii: 10.103

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Aug. 31, 2021

Availability

Academic Institutions and Nonprofits only
lentiGuide-Puro-pKO-library

Pooled Library

#190744

Purpose

CRISPR/Cas9 paired-guide RNA library to delete proximal poly(A) sites in mouse melanoma.

Depositor

Robert Bradley

Article

Gabel et al Nat Commun. 2024 Feb 1;15(1):959. doi: 1

Expression

Mammalian

Species

Mus musculus

Use

CRISPR, Lentiviral, and Mouse Targeting

Available since

Feb. 2, 2024

Availability

Academic Institutions and Nonprofits only
Human Genome-wide Intron Tagging Library, Frame 1

Pooled Library

#216134

Purpose

Library of intron-targeting sgRNAs for pooled tagging of proteins with GFP or other protein tags at their endogenous genomic locus using an intron tagging approach.

Depositor

Stefan Kubicek

Article

Reicher et al Nat Cell Biol. 2024 May;26(5):745-756. d

Expression

Mammalian

Use

CRISPR and Lentiviral

Available since

April 19, 2024

Availability

Academic Institutions and Nonprofits only
KSHV Tiling Library

Pooled Library

#180272

Purpose

sgRNA library tiling entire ~154 kb of the BAC16 Kaposi’s Sarcoma-associated Herpes viral genome. A guide every ~8 bp allows pooled screening of viral genome.

Depositor

Britt Glaunsinger

Article

Morgens et al PLoS Pathog. 2022 Jan 18;18(1):e1010236.

Expression

Mammalian

Species

Kaposi’s sarcoma-associated herpes virus

Use

Lentiviral

Available since

Feb. 11, 2022

Availability

Academic Institutions and Nonprofits only
EFS-mTSG

Pooled Library

#113584

Purpose

AAV-CRISPR library for pool mutagenesis of top tumor suppressor genes

Depositor

Sidi Chen

Article

Wang et al Sci Adv. 2018 Feb 28;4(2):eaao5508. doi:

Expression

Mammalian

Use

AAV, CRISPR, Lentiviral, and Luciferase

Available since

July 23, 2019

Availability

Academic Institutions and Nonprofits only
mTORC1 Focused library

Pooled Library

#164084

Purpose

Lentiviral CRISPR library targets human mTORC1 signaling pathway

Depositor

David Sabatini

Article

Condon et al Proc Natl Acad Sci U S A. 2021 Jan 26;11

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Jan. 11, 2021

Availability

Academic Institutions and Nonprofits only
Human sgRNA library Brunello in lentiGuide-Puro

Pooled Library

#73178

Purpose

Human sgRNA library in backbone lentiGuide-Puro targeting 19,114 genes and containing 76,441 unique sgRNAs along with 1000 non-targeting controls

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Has Service

Lentiviral Prep

Expression

Mammalian

Use

CRISPR and Lentiviral

Available since

Feb. 9, 2016

Availability

Academic Institutions and Nonprofits only

Showing: 1111 - 1140 of 94716 results

Results per page:

Sort results by:

PBbtCRISPRko.v1

pRG01-MCAP_MET

Lenti-human-TF-gRNA-puromycin

MORF library without GFP and mCherry controls

Human Kinase Domain-Focused CRISPR Knockout Library

Pan-cancer CasRx lncRNA Albarossa library

Mini-human AsCpf1-based human genome-wide knockout library

Human messenger-RBP sgRNA library

Human Paralog Knockout Library (pgPEN)

Self-targeting epegRNA library, Tiled edits (lRM001)

Mouse metabolism knockout library

Watermelon

FNLCR CRISPRa Cell Surface

Human Metabolic Gene CRISPRa sgRNA library

Human Lipid Droplet and Metabolism Library

RNA-binding protein pooled CRISPR knockout library

TBG-mTSG

Mouse Metabolic Gene CRISPRa sgRNA library

Mouse messenger-RBP sgRNA library

Perturb-seq GBC library

pRep-Cap Scanning Saturation Mutagenesis (SSM) pooled library

Human lentiviral CRISPR library_v1

mTF-CRISPRai

BARBEKO sgRNA library

lentiGuide-Puro-pKO-library

Human Genome-wide Intron Tagging Library, Frame 1

KSHV Tiling Library

EFS-mTSG

mTORC1 Focused library

Human sgRNA library Brunello in lentiGuide-Puro

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